Best TWAS P=1.79e-08 · Best GWAS P=7.16e-07 conditioned to 0.0656
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | PABPC4 | 0.10 | 0.10 | lasso | 4 | 0.10 | 3.4e-08 | 5.0 | -5.1 | 2.9e-07 | -0.99 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Breast Mammary Tissue | RP11-69E11.4 | 0.15 | 0.05 | enet | 32 | 0.05 | 8.8e-04 | 4.4 | 5.6 | 1.8e-08 | 0.63 | 0.05 | 0.90 | TRUE |
| 3 | GTEx | Nerve Tibial | RP11-69E11.8 | 0.05 | 0.00 | lasso | 3 | 0.01 | 6.9e-02 | 5.0 | -5.1 | 3.1e-07 | -0.99 | 0.04 | 0.77 | FALSE |