Best TWAS P=3.85e-12 · Best GWAS P=4.71e-12 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | AC010883.5 | 0.11 | 0.09 | lasso | 2 | 0.08 | 1.5e-06 | -6.9 | -6.9 | 3.8e-12 | 0.98 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZFP36L2 | 0.03 | 0.01 | blup | 38 | 0.01 | 1.1e-02 | -2.4 | 5.4 | 8.7e-08 | -0.79 | 0.02 | 0.51 | FALSE |