[Hub]/) : Traits : Diabetes diagnosed by doctor : ← →

chr2:26,655,745-28,402,863

Best TWAS P=2.29e-12 · Best GWAS P=7.61e-13 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	GTF3C2	0.06	0.09	lasso	8	0.08	7.2e-10	4.4	-5.2	2.2e-07	0.72	0.35	0.65	FALSE
2	CommonMind	Brain Pre-frontal Cortex	IFT172	0.06	0.09	enet	16	0.09	3.9e-11	4.3	5.5	3.9e-08	-0.75	0.44	0.56	FALSE
3	GTEx	Adipose Subcutaneous	AC074117.10	0.06	0.04	lasso	5	0.02	4.8e-03	5.2	-5.7	1.2e-08	0.65	0.49	0.22	FALSE
4	GTEx	Cells Transformed fibroblasts	AC074117.10	0.21	0.19	enet	23	0.18	1.6e-13	5.2	-5.6	2.1e-08	0.66	0.90	0.10	FALSE
5	GTEx	Esophagus Gastroesophageal Junction	AC074117.10	0.12	0.13	enet	9	0.09	4.9e-04	4.2	-5.2	2.0e-07	0.64	0.46	0.26	FALSE
6	GTEx	Esophagus Mucosa	AC074117.10	0.12	0.14	lasso	8	0.14	2.1e-09	5.2	-5.6	2.1e-08	0.74	0.93	0.07	FALSE
7	GTEx	Esophagus Muscularis	NRBP1	0.07	0.04	lasso	6	0.04	1.3e-03	5.2	-5.6	1.7e-08	0.82	0.02	0.96	FALSE
8	GTEx	Esophagus Muscularis	AC074117.10	0.17	0.14	enet	5	0.09	6.6e-06	5.2	-5.4	7.2e-08	0.65	0.78	0.20	FALSE
9	GTEx	Nerve Tibial	NRBP1	0.06	0.00	enet	9	0.02	2.0e-02	5.2	-5.5	3.6e-08	0.61	0.34	0.53	FALSE
10	GTEx	Ovary	AC074117.10	0.16	0.04	enet	9	0.05	2.0e-02	4.5	-5.5	2.9e-08	0.77	0.05	0.77	FALSE
11	GTEx	Testis	NRBP1	0.16	0.09	lasso	3	0.06	1.8e-03	5.2	-6.1	1.2e-09	0.80	0.03	0.96	FALSE
12	GTEx	Testis	AC074117.10	0.14	0.08	lasso	6	0.12	4.5e-06	4.6	-6.2	4.2e-10	0.85	0.04	0.96	FALSE
13	METSIM	Adipose	NRBP1	0.06	0.09	lasso	3	0.08	1.6e-12	5.2	-5.4	5.7e-08	0.67	1.00	0.00	FALSE
14	METSIM	Adipose	PREB	0.04	0.01	bslmm	302	0.02	5.6e-04	2.3	5.2	2.2e-07	-0.36	0.08	0.29	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	FTH1P3	0.04	0.01	bslmm	280	0.02	2.8e-03	5.2	-5.2	2.5e-07	0.65	0.04	0.71	FALSE
16	YFS	Blood	NRBP1	0.01	0.01	lasso	6	0.01	9.1e-06	4.6	-5.1	3.0e-07	0.61	0.99	0.01	FALSE
17	The Cancer Genome Atlas	Glioblastoma Multiforme	NRBP1	0.15	0.10	lasso	2	0.10	5.8e-04	5.2	-5.2	1.6e-07	0.67	0.00	0.64	FALSE
18	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FNDC4	0.13	0.06	lasso	2	0.05	1.1e-03	-7.2	7.0	2.3e-12	-0.99	0.00	0.95	TRUE