[Hub]/) : Traits : Diabetes diagnosed by doctor :

chr2:26,655,745-28,402,863

Best TWAS P=2.29e-12 · Best GWAS P=7.61e-13 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GTF3C2 0.06 0.09 lasso 8 0.08 7.2e-10 4.4 -5.2 2.2e-07 0.72 0.35 0.65 FALSE
2 CommonMind Brain Pre-frontal Cortex IFT172 0.06 0.09 enet 16 0.09 3.9e-11 4.3 5.5 3.9e-08 -0.75 0.44 0.56 FALSE
3 GTEx Adipose Subcutaneous AC074117.10 0.06 0.04 lasso 5 0.02 4.8e-03 5.2 -5.7 1.2e-08 0.65 0.49 0.22 FALSE
4 GTEx Cells Transformed fibroblasts AC074117.10 0.21 0.19 enet 23 0.18 1.6e-13 5.2 -5.6 2.1e-08 0.66 0.90 0.10 FALSE
5 GTEx Esophagus Gastroesophageal Junction AC074117.10 0.12 0.13 enet 9 0.09 4.9e-04 4.2 -5.2 2.0e-07 0.64 0.46 0.26 FALSE
6 GTEx Esophagus Mucosa AC074117.10 0.12 0.14 lasso 8 0.14 2.1e-09 5.2 -5.6 2.1e-08 0.74 0.93 0.07 FALSE
7 GTEx Esophagus Muscularis NRBP1 0.07 0.04 lasso 6 0.04 1.3e-03 5.2 -5.6 1.7e-08 0.82 0.02 0.96 FALSE
8 GTEx Esophagus Muscularis AC074117.10 0.17 0.14 enet 5 0.09 6.6e-06 5.2 -5.4 7.2e-08 0.65 0.78 0.20 FALSE
9 GTEx Nerve Tibial NRBP1 0.06 0.00 enet 9 0.02 2.0e-02 5.2 -5.5 3.6e-08 0.61 0.34 0.53 FALSE
10 GTEx Ovary AC074117.10 0.16 0.04 enet 9 0.05 2.0e-02 4.5 -5.5 2.9e-08 0.77 0.05 0.77 FALSE
11 GTEx Testis NRBP1 0.16 0.09 lasso 3 0.06 1.8e-03 5.2 -6.1 1.2e-09 0.80 0.03 0.96 FALSE
12 GTEx Testis AC074117.10 0.14 0.08 lasso 6 0.12 4.5e-06 4.6 -6.2 4.2e-10 0.85 0.04 0.96 FALSE
13 METSIM Adipose NRBP1 0.06 0.09 lasso 3 0.08 1.6e-12 5.2 -5.4 5.7e-08 0.67 1.00 0.00 FALSE
14 METSIM Adipose PREB 0.04 0.01 bslmm 302 0.02 5.6e-04 2.3 5.2 2.2e-07 -0.36 0.08 0.29 FALSE
15 ROSMAP Brain Pre-frontal Cortex FTH1P3 0.04 0.01 bslmm 280 0.02 2.8e-03 5.2 -5.2 2.5e-07 0.65 0.04 0.71 FALSE
16 YFS Blood NRBP1 0.01 0.01 lasso 6 0.01 9.1e-06 4.6 -5.1 3.0e-07 0.61 0.99 0.01 FALSE
17 The Cancer Genome Atlas Glioblastoma Multiforme NRBP1 0.15 0.10 lasso 2 0.10 5.8e-04 5.2 -5.2 1.6e-07 0.67 0.00 0.64 FALSE
18 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma FNDC4 0.13 0.06 lasso 2 0.05 1.1e-03 -7.2 7.0 2.3e-12 -0.99 0.00 0.95 TRUE