Best TWAS P=3.51e-16 · Best GWAS P=1.3e-16 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CENPW | 0.04 | 0.06 | lasso | 10 | 0.06 | 2.4e-07 | -8.2 | 8.2 | 3.5e-16 | -1.00 | 0.02 | 0.98 | TRUE |
| 2 | GTEx | Heart Atrial Appendage | CENPW | 0.17 | 0.01 | enet | 15 | 0.06 | 1.8e-03 | -7.9 | 7.7 | 1.1e-14 | -0.70 | 0.03 | 0.48 | FALSE |
| 3 | METSIM | Adipose | CENPW | 0.02 | 0.02 | blup | 189 | 0.01 | 8.3e-03 | -7.9 | 6.9 | 5.7e-12 | -0.74 | 0.02 | 0.74 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CENPW | 0.04 | 0.05 | lasso | 5 | 0.05 | 2.6e-06 | -8.1 | 8.1 | 5.6e-16 | -0.97 | 0.02 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CENPW | 0.04 | 0.06 | blup | 35 | 0.05 | 9.2e-07 | -8.0 | 8.0 | 1.5e-15 | -0.98 | 0.02 | 0.98 | FALSE |