Best TWAS P=2.69e-07 · Best GWAS P=2.54e-07 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | AKAP8 | 0.32 | 0.39 | lasso | 5 | 0.39 | 5.5e-51 | -5 | -5.1 | 2.7e-07 | 0.99 | 0.03 | 0.97 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | AKAP8 | 0.27 | 0.32 | bslmm | 553 | 0.33 | 2.0e-43 | -5 | -5.1 | 2.7e-07 | 0.98 | 0.03 | 0.97 | FALSE |