[Hub]/) : Traits : Birth weight of first child : ← →

chr1:11,181,327-12,600,396

Best TWAS P=3.9e-10 · Best GWAS P=2.37e-11 conditioned to 0.0879

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Skin Not Sun Exposed Suprapubic CLCN6 0.12 0.03 lasso 3 0.04 3.3e-03 4.2 6.1 1.0e-09 0.83 0.01 0.96 FALSE
2 GTEx Skin Sun Exposed Lower leg CLCN6 0.08 0.00 lasso 3 0.01 7.9e-02 3.3 5.5 4.2e-08 0.67 0.03 0.67 FALSE
3 GTEx Spleen CLCN6 0.21 0.10 lasso 3 0.06 1.3e-02 4.9 5.2 1.7e-07 0.86 0.04 0.72 FALSE
4 METSIM Adipose CLCN6 0.09 0.04 blup 480 0.06 1.6e-09 5.4 5.8 6.9e-09 0.64 0.06 0.94 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma CLCN6 0.06 0.06 blup 104 0.06 5.0e-12 4.7 5.8 5.3e-09 0.76 0.26 0.74 FALSE
6 The Cancer Genome Atlas Colon Adenocarcinoma CLCN6 0.14 0.05 blup 104 0.09 1.2e-05 6.6 6.2 4.8e-10 0.81 0.01 0.98 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CLCN6 0.04 0.06 lasso 2 0.05 1.1e-06 4.7 5.3 1.1e-07 0.70 0.10 0.89 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma CLCN6 0.06 0.04 blup 104 0.04 5.2e-06 6.5 6.2 5.0e-10 0.91 0.01 0.99 FALSE
9 The Cancer Genome Atlas Stomach Adenocarcinoma CLCN6 0.07 0.04 blup 104 0.05 2.4e-04 6.6 5.8 7.8e-09 0.93 0.01 0.98 TRUE
10 The Cancer Genome Atlas Thyroid Carcinoma CLCN6 0.08 0.02 blup 104 0.05 2.5e-05 5.4 6.3 3.9e-10 0.63 0.12 0.87 TRUE