Best TWAS P=7.68e-09 · Best GWAS P=5.93e-08 conditioned to 0.349
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | BARD1 | 0.13 | 0.04 | lasso | 3 | 0.07 | 4.6e-04 | 4.2 | 5.2 | 2.2e-07 | -0.76 | 0.05 | 0.71 | FALSE |
| 2 | GTEx | Heart Atrial Appendage | BARD1 | 0.15 | 0.04 | lasso | 3 | 0.09 | 8.5e-05 | -5.0 | 5.4 | 8.1e-08 | -0.86 | 0.03 | 0.96 | FALSE |
| 3 | GTEx | Pituitary | BARD1 | 0.29 | 0.25 | lasso | 3 | 0.26 | 2.3e-07 | -5.3 | 5.8 | 7.7e-09 | -0.85 | 0.01 | 0.98 | TRUE |
| 4 | YFS | Blood | BARD1 | 0.24 | 0.14 | enet | 40 | 0.27 | 5.8e-90 | -3.0 | 5.3 | 1.2e-07 | -0.80 | 0.87 | 0.03 | FALSE |