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Forced vital capacity (FVC)
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chr14:92,286,262-93,847,625
Best TWAS P=3.59e-16 · Best GWAS P=3.8e-17 conditioned to 1
92.2M
92.4M
92.6M
92.8M
93M
93.2M
93.4M
93.6M
93.8M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Colon Sigmoid
RIN3
0.24
0.17
lasso
6
0.11
9.3e-05
8.2
-8.2
3.6e-16
-0.98
0.00
0.99
TRUE
2
GTEx
Esophagus Muscularis
RIN3
0.17
0.05
lasso
6
0.06
1.6e-04
6.0
-5.3
1.1e-07
-0.48
0.11
0.57
FALSE