Hub : Traits :

Forced vital capacity (FVC)

2917 significantly associated models · 605 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 16142960 18461490 16 8 3.1e-32 3.1e-32 1.0e+00 100 ATP13A2 CROCC ESPNP MST1L MST1P2 RP11-108M9.5
2 1 22197336 22718991 1 1 3.7e-14 1.5e-11 2.4e-04 70 WNT4
3 1 25475418 27971502 10 4 2.9e-13 1.6e-12 6.2e-01 100 DHDDS NUDC RPS6KA1 TRIM63
4 1 37764586 39186794 2 1 1.3e-07 1.1e-07 1.0e+00 100 FHL3
5 1 40748755 42542658 5 1 2.0e-29 3.1e-24 7.7e-01 100 SCMH1
6 1 67814420 69212053 1 1 4.0e-08 3.7e-08 5.2e-02 88 DIRAS3
7 1 87083322 87628173 1 1 2.7e-07 8.0e-07 5.4e-01 98 SEP15
8 2 23453834 25889403 8 11 9.9e-23 2.8e-21 NaN NaN ADCY3 NCOA1 PTRHD1 RP11-443B20.1 UBXN2A
9 2 35883253 37567226 5 1 1.8e-12 1.3e-11 5.1e-01 99 FEZ2
10 2 46117914 47538477 1 1 1.5e-08 5.2e-10 9.7e-03 83 PIGF
11 2 55079242 56843605 2 2 4.8e-53 3.1e-69 1.5e-09 88 EFEMP1
12 2 69678079 71228388 4 1 6.5e-12 6.9e-10 1.5e-03 74 FAM136A
13 2 100029106 101629737 2 1 3.2e-08 2.7e-08 1.1e-03 66 AC092667.2
14 2 134794256 137435625 7 1 3.7e-12 2.4e-11 1.5e-04 68 DARS
15 2 171478402 173114238 2 1 5.4e-12 2.8e-08 1.2e-02 80 CYBRD1
16 2 177559549 179672547 4 1 4.9e-12 1.2e-10 1.5e-01 95 AC073834.3
17 2 202434393 204433184 3 1 8.5e-08 3.6e-08 6.0e-03 75 NOP58
18 2 218300530 220374137 11 2 1.4e-14 7.0e-10 1.2e-08 14 CXCR2 PNKD
19 2 231628878 233349588 4 2 2.6e-10 1.7e-09 3.5e-02 88 C2orf52 RP11-690I21.1
20 2 241332207 243048760 6 6 3.1e-23 9.4e-19 NaN NaN BOK C2orf54 MTERFD2 PASK SEPT2
21 3 8294862 8858201 1 1 3.4e-09 3.7e-10 7.2e-04 71 LMCD1
22 3 32497274 33950934 1 1 1.2e-10 3.9e-11 1.2e-09 15 SUSD5
23 3 48702606 50448632 2 1 7.5e-08 5.8e-07 5.5e-04 52 RNF123
24 3 52166147 53560321 1 1 1.4e-07 2.0e-06 1.0e+00 100 RP5-966M1.6
25 3 70757099 71880670 1 1 1.9e-10 8.7e-13 2.5e-05 65 FOXP1
26 3 128276332 129714372 2 1 3.4e-14 4.0e-14 5.0e-04 79 H1FX
27 3 140250247 141867638 2 3 6.2e-24 1.5e-24 1.0e+00 100 ACPL2 ZBTB38
28 3 157125828 159106064 5 1 4.6e-22 4.5e-19 4.3e-03 90 RP11-538P18.2
29 3 171513388 172924003 2 2 7.5e-09 3.7e-14 5.9e-05 72 FNDC3B TNFSF10
30 3 196072442 197724684 1 2 3.4e-09 3.0e-10 1.6e-01 95 DLG1
31 4 673778 2058475 2 1 3.4e-09 1.7e-06 4.3e-01 97 CRIPAK
32 4 2233366 4219590 4 6 3.0e-09 2.9e-11 NaN NaN DOK7 LRPAP1 MFSD10
33 4 17104059 18507692 2 7 4.9e-46 5.4e-41 NaN NaN DCAF16 NCAPG
34 4 57080198 58531645 4 1 2.2e-10 3.4e-10 1.9e-01 96 NOA1
35 4 76660500 78402379 1 1 8.9e-09 3.2e-12 5.3e-05 66 SHROOM3
36 4 100238413 100791805 1 1 4.8e-09 1.8e-07 9.3e-01 100 MTTP
37 4 105373669 107622327 5 2 7.4e-17 2.3e-19 3.7e-02 95 INTS12 PPA2
38 4 144882744 146788825 3 2 1.5e-31 2.6e-30 9.1e-01 100 ANAPC10 OTUD4
39 5 55862596 56435767 1 1 3.6e-08 9.9e-09 1.3e-05 42 MAP3K1
40 5 64196669 65022213 1 1 1.2e-08 1.8e-10 4.4e-03 80 ADAMTS6
41 5 77052232 78753539 2 1 5.4e-20 7.9e-23 1.1e-04 85 AP3B1
42 5 107390303 109224099 1 1 3.7e-11 7.2e-13 2.4e-05 65 FER
43 5 114443019 115851911 1 1 1.2e-08 2.8e-09 5.1e-02 89 CDO1
44 5 121480516 123002130 2 2 7.6e-10 4.5e-13 1.0e-03 79 CEP120 CTB-36H16.2
45 5 126587995 128220643 4 1 8.0e-10 3.3e-09 3.3e-03 75 CTC-228N24.3
46 5 133164490 134935530 4 5 1.4e-12 1.6e-09 7.0e-07 32 CAMLG SAR1B
47 5 139348915 141214127 8 1 9.5e-09 2.8e-07 8.3e-01 100 ZMAT2
48 5 147825590 149338157 1 1 6.4e-08 9.9e-08 1.0e+00 100 ABLIM3
49 5 175662866 177260129 4 2 3.6e-13 1.0e-12 3.2e-02 91 RAB24 UIMC1
50 6 25285943 26689223 1 1 1.7e-13 3.4e-13 1.2e-05 64 U91328.21
51 6 33662667 36158878 13 10 9.3e-22 3.4e-32 NaN NaN NUDT3 PACSIN1 RPL10A TCP11 TEAD3 ZNF76
52 6 75319716 77324522 3 1 1.7e-10 1.3e-08 2.4e-01 96 FILIP1
53 6 80120201 81763771 2 1 1.6e-11 1.2e-11 2.5e-03 80 BCKDHB
54 6 108994161 110844259 9 1 3.8e-14 3.4e-14 1.0e+00 100 RP11-425D10.10
55 6 115880851 117481404 3 1 3.5e-09 7.5e-10 1.0e-02 83 FAM26F
56 6 125970401 127355237 1 1 8.9e-31 4.6e-33 5.2e-04 92 CENPW
57 6 129638583 132080991 4 2 6.3e-26 4.5e-27 7.3e-15 48 LOC285733 RP11-73O6.3
58 6 134905567 136516257 3 1 8.9e-09 2.7e-09 4.1e-03 77 AHI1
59 6 141924760 143855272 3 3 8.9e-30 1.5e-31 1.0e+00 100 GPR126 NMBR
60 6 158041511 159632250 1 1 3.3e-14 2.3e-11 4.8e-04 73 TULP4
61 7 2032803 3581391 2 1 1.0e-12 3.2e-12 2.3e-02 89 GNA12
62 7 22449883 24382726 4 3 3.9e-12 1.9e-21 9.7e-07 74 CCDC126 KLHL7 TRA2A
63 7 45255940 46658015 1 1 1.9e-08 3.8e-13 1.6e-11 14 IGFBP3
64 7 91380845 93160671 3 1 3.8e-13 3.8e-12 2.4e-01 97 CDK6
65 7 139700516 141316834 4 2 1.1e-10 9.4e-11 1.0e+00 100 BRAF NDUFB2
66 7 149847287 151252618 2 1 1.2e-09 7.8e-13 2.0e-05 65 AOC1
67 8 56269387 57683880 2 1 2.1e-13 5.7e-23 2.3e-11 54 RPS20
68 8 119737284 121136001 1 1 1.5e-10 2.2e-10 3.5e-09 14 NOV
69 8 123101743 124679448 1 1 6.8e-10 1.6e-10 6.3e-03 82 ZHX2
70 8 130517157 131045893 1 1 2.1e-20 5.9e-18 8.4e-04 85 GSDMC
71 9 14857740 16758776 1 1 1.9e-13 9.4e-14 6.4e-02 94 CCDC171
72 9 96326127 100114913 11 8 5.0e-22 1.7e-28 1.1e-03 91 C9orf3 ERCC6L2 HABP4 PTCH1 RP11-435O5.4 RP11-435O5.5 ZNF169
73 9 100871717 102304304 1 1 2.7e-08 1.4e-08 3.0e-06 32 GALNT12
74 9 127218258 128610269 1 1 6.5e-08 5.9e-07 4.4e-02 84 PRPS1P2
75 9 135521303 137034272 3 3 2.1e-08 2.2e-11 8.9e-03 85 ABO CACFD1 SURF1
76 9 138403706 139836362 1 1 6.1e-22 8.0e-20 3.0e-01 99 QSOX2
77 10 11515875 12989666 2 1 2.3e-10 1.8e-10 1.3e-03 75 CDC123
78 10 28113533 29610861 2 1 7.4e-08 3.1e-10 9.9e-11 -6 WAC-AS1
79 10 30887952 31565621 1 1 1.6e-07 3.8e-08 1.8e-02 81 ZNF438
80 10 74317852 76266883 3 2 9.9e-08 9.5e-08 1.0e+00 100 DNAJC9-AS1 NDST2
81 10 76664253 80383574 3 2 4.3e-09 8.5e-11 4.2e-04 70 C10orf11 DLG5
82 10 80443273 81901722 1 1 2.6e-11 2.3e-07 1.1e-02 76 ZCCHC24
83 10 88156839 89647154 1 1 3.1e-07 6.3e-06 8.2e-01 100 FAM35A
84 10 101975269 103362569 2 1 7.1e-09 1.3e-08 1.0e+00 100 RP11-179B2.2
85 10 103527782 105275242 4 1 3.1e-10 2.3e-07 9.4e-01 100 TMEM180
86 10 123438113 124889817 2 2 2.3e-09 2.8e-24 1.6e-15 39 ARMS2 PLEKHA1
87 11 18170688 18673155 1 1 7.7e-08 5.0e-08 2.8e-02 84 LDHA
88 11 32365430 33799671 3 1 1.2e-10 1.2e-08 7.7e-02 90 TCP11L1
89 11 46064974 48783497 18 1 2.5e-12 3.9e-11 3.6e-01 98 C1QTNF4
90 11 61678576 63078986 3 1 1.3e-08 2.8e-08 1.7e-07 11 EML3
91 11 64663227 69549801 23 10 1.3e-38 2.5e-35 1.0e+00 100 CCDC87 CTD-3074O7.12 CTD-3074O7.5 KCNK7 MRGPRF RAD9A RPS6KB2 SF3B2 TPCN2
92 11 76827992 78216992 2 1 1.8e-08 5.0e-06 3.0e-01 95 AP000580.1
93 11 116022447 117662909 1 1 1.9e-08 1.9e-10 4.9e-06 48 SIK3
94 11 118268613 119659753 1 1 6.8e-09 2.2e-08 5.0e-06 33 HMBS
95 12 403545 2299048 1 1 2.3e-08 5.1e-11 1.3e-06 46 ERC1
96 12 14713793 15223230 1 1 2.6e-07 2.2e-06 2.6e-01 94 C12orf60
97 12 20151739 21604108 1 1 7.5e-08 2.4e-09 9.9e-06 45 SLCO1C1
98 12 27616589 29042392 1 1 9.1e-14 4.1e-11 3.7e-01 98 RP11-967K21.1
99 12 30084002 31526510 1 1 1.2e-13 4.9e-14 1.0e+00 100 IPO8
100 12 46077695 47465082 1 1 4.5e-08 3.9e-10 2.4e-03 76 SLC38A2
101 12 55633142 57452308 11 1 7.3e-09 3.9e-08 8.7e-01 100 RP11-977G19.11
102 12 64519806 66337026 2 1 1.4e-11 3.4e-20 7.4e-24 -20 LEMD3
103 12 93165619 94589220 1 1 8.7e-11 2.9e-24 7.8e-16 37 MRPL42
104 12 101575652 103101412 3 2 2.8e-08 2.7e-10 8.0e-02 92 C12orf48 DRAM1
105 13 49375072 51390447 4 7 3.9e-18 4.2e-18 1.0e+00 100 DLEU2 EBPL
106 13 77787826 79188028 1 1 8.6e-08 1.5e-07 7.9e-02 89 EDNRB
107 14 36900126 37890433 1 1 3.7e-09 8.9e-10 3.3e-03 77 SLC25A21
108 14 72734342 74120838 1 1 2.5e-07 1.1e-07 8.1e-03 75 RP11-109N23.6
109 14 92286262 93847625 1 1 3.6e-16 3.8e-17 1.0e+00 100 RIN3
110 14 102288663 103675360 1 1 2.6e-08 7.6e-07 6.8e-01 99 ANKRD9
111 15 39530508 41012695 1 1 1.1e-09 4.4e-08 2.7e-06 27 EIF2AK4
112 15 50649361 52091785 1 1 7.7e-08 1.5e-09 3.2e-03 76 TNFAIP8L3
113 15 66797492 68492262 2 1 4.6e-09 1.3e-10 7.1e-04 72 AAGAB
114 15 71418503 73087366 2 1 4.1e-11 2.2e-09 8.6e-01 100 MYO9A
115 15 73524629 78022087 13 5 7.5e-21 6.9e-27 9.2e-19 32 CLK3 LOXL1-AS1 MAN2C1 RCN2
116 15 78135979 79537269 1 1 2.4e-07 3.9e-08 6.0e-02 88 PSMA4
117 15 83167559 85883064 11 3 1.5e-12 8.5e-20 4.0e-05 80 AC103965.1 RP11-182J1.14 WHAMM
118 15 89171135 89701439 2 2 1.2e-08 3.9e-14 1.2e-08 43 HAPLN3 MFGE8
119 15 99816860 101209341 1 1 3.0e-08 4.4e-14 1.3e-11 20 CTD-3076O17.1
120 16 86671 1488646 3 1 3.6e-08 5.8e-08 1.0e+00 100 NARFL
121 16 2510603 5510848 12 3 1.2e-15 3.9e-14 3.9e-03 85 CLUAP1 ZNF213 ZNF500
122 16 13697975 14759768 1 1 2.6e-08 9.0e-09 1.2e-03 68 RP11-65J21.3
123 16 29580611 31833122 14 9 3.7e-14 2.3e-12 1.0e+00 100 BCKDK BCL7C HSD3B7 MIR4519 RNF40 STX1B STX4 TBX6 VKORC1
124 16 68523336 71093625 14 9 4.7e-16 2.2e-25 NaN NaN CLEC18A COG4 NFAT5 NOB1 PDXDC2 TMED6
125 16 71848959 72342280 1 1 9.0e-08 2.2e-07 5.3e-02 86 HP
126 16 80779331 82901701 2 2 1.7e-08 1.2e-07 4.2e-01 98 CMIP MPHOSPH6
127 16 88030355 90172696 6 2 2.8e-10 1.9e-08 2.1e-05 43 CHMP1A SNAI3-AS1
128 17 970413 2420934 2 1 8.3e-08 5.6e-07 7.8e-01 100 SERPINF1
129 17 27200734 28952286 7 1 5.0e-10 2.7e-09 2.3e-01 96 ANKRD13B
130 17 36244358 37644854 1 1 1.7e-08 1.6e-07 1.3e-05 30 PIP4K2B
131 17 41946180 47688526 40 11 8.6e-42 5.6e-33 NaN NaN ARL17B ATP5G1 CDK5RAP3 KANSL1 LOC644172 LRRC37A LRRC37A2 LRRC37A4 MGC57346 PLCD3
132 17 60821100 64251733 20 9 9.3e-31 3.9e-28 NaN NaN AXIN2 CCDC47 CD79B CYB561 DDX42 PLEKHM1P SMARCD2
133 17 78665405 80866427 11 2 1.3e-16 1.8e-12 9.8e-05 69 DCXR RP11-1055B8.4
134 18 69836 907710 1 1 2.7e-07 3.0e-06 5.4e-03 64 USP14
135 18 59159599 60668346 1 1 2.1e-09 1.5e-05 7.7e-01 100 KIAA1468
136 19 3309021 4732167 1 1 1.1e-07 1.0e-09 6.3e-04 69 PIAS4
137 19 8367158 8848856 1 1 3.4e-09 6.5e-13 2.2e-08 39 MYO1F
138 19 10068513 11459260 2 1 5.8e-09 2.1e-08 7.4e-02 90 ILF3-AS1
139 19 40403029 43237764 6 2 1.9e-11 2.1e-11 1.0e+00 100 GSK3A SHKBP1
140 19 45496303 46981943 3 3 5.5e-09 4.3e-09 7.6e-02 91 DMPK RSPH6A SNRPD2
141 20 9925555 11347455 1 1 2.3e-09 5.2e-09 5.7e-03 78 JAG1
142 20 20857022 21474355 1 1 1.8e-07 6.9e-07 1.6e-01 92 PLK1S1
143 20 31382860 34697305 9 3 1.6e-11 5.4e-11 4.3e-01 98 E2F1 GDF5 TP53INP2
144 20 44824099 46516716 1 1 1.1e-07 8.4e-16 1.4e-09 43 EYA2
145 20 46551079 48603940 9 7 6.3e-22 7.2e-24 1.0e+00 100 ARFGEF2 C20orf199 CSE1L DDX27 ZFAS1
146 20 61522825 62912463 12 1 3.4e-16 4.3e-16 1.0e+00 100 LIME1
147 22 29707908 31171274 3 4 4.1e-13 3.0e-13 8.5e-01 100 CTA-85E5.10 HORMAD2 MTMR3

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Bipolar Disorder (2018) 1.1 1 0 0.0 0.00 1.0e+00 AC103965.1
Bipolar Disorder or Schizophrenia 1.1 9 4 8.9 -0.18 6.5e-01 AC103965.1 BRAF CTD-3074O7.12 CTD-3074O7.5 PACSIN1 PSMA4 RP5-966M1.6 U91328.21 ZMAT2
Depressed Affect (Nagel 2018) 1.7 7 4 8.9 -0.69 5.6e-02 ARL17B BCL7C HORMAD2 KANSL1 LRRC37A LRRC37A2 STX1B
Intelligence (Savage-Jansen 2018) 1.8 18 12 26.7 0.82 1.4e-06 ARFGEF2 C1QTNF4 CENPW CSE1L DCAF16 DDX27 FOXP1 HABP4 LRRC37A2 NCAPG PPA2 RNF123 RP11-435O5.5 RP5-966M1.6 TULP4 UBXN2A ZFAS1 ZMAT2
Neuroticism (Nagel 2018) 1.9 13 10 22.2 -0.29 2.9e-01 ARL17B BCKDK BCL7C CENPW HORMAD2 HSD3B7 KANSL1 LRRC37A LRRC37A2 MGC57346 PTCH1 STX1B STX4
Schizophrenia (2018) 1.1 4 2 4.4 0.67 3.3e-01 AC103965.1 PSMA4 U91328.21 ZMAT2
Schizophrenia vs Biploar Disorder 1.1 1 1 2.2 0.00 1.0e+00 CSE1L
Worry (Nagel 2018) 1.7 12 3 6.7 -0.02 9.5e-01 BCKDK BCL7C CENPW CTA-85E5.10 HORMAD2 HSD3B7 LRRC37A LRRC37A2 MTMR3 PTCH1 RP5-966M1.6 STX1B
Alzheimer’s Disease (including proxy) 1.3 2 1 2.2 0.00 1.0e+00 BCKDK RSPH6A
Crohns Disease (2017) 1.4 7 6 13.3 -0.45 1.9e-01 ADCY3 HORMAD2 LIME1 MTMR3 NDST2 RP11-443B20.1 ZBTB38
Irritable Bowel Disease (IBD) 1.6 9 4 8.9 -0.75 4.8e-03 ADCY3 CXCR2 DOK7 HORMAD2 LIME1 MTMR3 NCOA1 PTRHD1 RP11-443B20.1
Ulcerative Colitis (UC) 1.5 3 1 2.2 0.00 1.0e+00 DOK7 LIME1 RNF123
Major Depression (MDD) 1.2 1 0 0.0 0.00 1.0e+00 PTCH1
Reaction Time 1.3 4 0 0.0 0.12 8.8e-01 ADCY3 CSE1L PIAS4 TMEM180
Verbal and Numeric Reasoning (VNR) 2.0 17 10 22.2 0.71 7.0e-04 ADCY3 ARFGEF2 C1QTNF4 CENPW CSE1L DCAF16 DDX27 FOXP1 HABP4 NCAPG PPA2 RNF123 TULP4 U91328.21 UBXN2A ZFAS1 ZMAT2
Breast Cancer 1.8 8 8 17.8 -0.41 1.9e-01 ADCY3 LRRC37A LRRC37A2 MAP3K1 RIN3 RP11-443B20.1 RP11-73O6.3 ZBTB38
Ovarian Cancer 1.7 4 3 6.7 0.95 1.5e-02 KANSL1 LOC644172 LRRC37A LRRC37A2
Prostate Cancer 1.1 2 0 0.0 0.00 1.0e+00 LIME1 TMEM180
Bipolar Disorder (2011) 1.8 1 0 0.0 0.00 1.0e+00 RP5-966M1.6
Body Mass Index (BMI) (2010) 1.6 3 1 2.2 -0.99 1.1e-03 ADCY3 C1QTNF4 RP11-443B20.1
Coronary Artery Disease (CAD) 1.4 1 0 0.0 0.00 1.0e+00 DCAF16
Crohns Disease (2012) 1.4 4 1 2.2 -0.46 4.3e-01 ADCY3 HORMAD2 LIME1 MTMR3
HbA1C 1.1 1 0 0.0 0.00 1.0e+00 ABO
HDL Cholesterol 1.3 3 3 6.7 0.00 1.0e+00 C1QTNF4 MYO1F SIK3
LDL Cholesterol 1.5 2 2 4.4 0.00 1.0e+00 ABO CACFD1
Neuroticism (2016) 1.3 2 0 0.0 0.00 1.0e+00 LRRC37A LRRC37A2
Primary Biliary Cirrhosis 1.3 1 0 0.0 0.00 1.0e+00 LRRC37A2
Schizophrenia (2014) 1.1 1 1 2.2 0.00 1.0e+00 AC103965.1
Triglycerides 1.2 1 0 0.0 0.00 1.0e+00 BCKDK
Ulcerative Colitis 1.5 1 1 2.2 0.00 1.0e+00 LIME1
Blood Eosinophil Count 1.5 42 29 64.4 -0.29 3.5e-02 AAGAB ABO ADCY3 AHI1 ARL17B ATP5G1 CACFD1 CDK6 CTC-228N24.3 DLEU2 EBPL FAM136A FAM26F GNA12 GSK3A KANSL1 LRRC37A LRRC37A2 MGC57346 MRGPRF MYO1F NARFL NOA1 NOB1 NUDT3 PACSIN1 PDXDC2 RIN3 RNF40 RP11-109N23.6 RP11-425D10.10 RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 RPL10A SEPT2 TBX6 TCP11 TEAD3 TRIM63 WAC-AS1 ZNF169
Blood Platelet Count 1.2 53 43 95.6 -0.73 5.1e-11 ABO ANKRD13B ANKRD9 AP000580.1 ARL17B C1QTNF4 CACFD1 CDK6 CEP120 CTA-85E5.10 CXCR2 DCAF16 DDX42 DMPK E2F1 EDNRB FAM136A FER GNA12 HABP4 KANSL1 LIME1 LMCD1 LOC644172 LRRC37A LRRC37A4 MAN2C1 MGC57346 MIR4519 NARFL NCAPG NOA1 NUDT3 OTUD4 PACSIN1 PNKD RIN3 RNF40 RP11-109N23.6 RP11-425D10.10 RP5-966M1.6 SCMH1 SIK3 SMARCD2 SURF1 TBX6 TCP11 TEAD3 TMEM180 TULP4 ZCCHC24 ZHX2 ZNF500
Blood Red Count 2.6 63 45 100.0 -0.06 6.0e-01 ABO AC103965.1 ANKRD13B AOC1 ARL17B ATP13A2 BCKDK BCL7C C20orf199 CACFD1 CCDC87 CD79B CDK5RAP3 CENPW CLEC18A CSE1L CTD-3074O7.12 CTD-3074O7.5 CXCR2 DARS DDX27 DDX42 EIF2AK4 FAM136A GPR126 HSD3B7 KANSL1 KCNK7 LIME1 LOC644172 LRRC37A LRRC37A2 LRRC37A4 MAN2C1 MGC57346 MIR4519 MST1L MST1P2 MYO9A NCOA1 NFAT5 NOB1 NOV PIAS4 RAB24 RAD9A RCN2 RP11-109N23.6 RP11-435O5.5 RP11-73O6.3 RP11-977G19.11 RP5-966M1.6 RPS6KA1 SEPT2 SHKBP1 SLC25A21 SNAI3-AS1 STX1B STX4 SURF1 TBX6 VKORC1 ZBTB38
Blood White Count 1.6 59 36 80.0 -0.59 7.1e-08 ABO ADCY3 AHI1 ANKRD13B ARL17B C1QTNF4 CACFD1 CCDC126 CCDC47 CDK5RAP3 CDK6 CENPW CEP120 CLEC18A CTB-36H16.2 CXCR2 CYB561 DCAF16 DDX42 DLG5 EBPL EDNRB FER FNDC3B GNA12 GSK3A HABP4 HORMAD2 HSD3B7 KANSL1 LIME1 LOC644172 LRRC37A LRRC37A4 MAN2C1 NOA1 NOB1 PACSIN1 PDXDC2 PNKD PTRHD1 RCN2 RIN3 RP11-435O5.5 RP11-443B20.1 RP11-73O6.3 RPL10A SCMH1 SIK3 SMARCD2 TMEM180 TPCN2 TRA2A TULP4 UBXN2A WAC-AS1 ZHX2 ZNF169 ZNF76
Heel T-Score 2.8 74 57 126.7 -0.36 5.3e-04 AAGAB ABO ADAMTS6 ADCY3 ANAPC10 ANKRD13B AP000580.1 ARL17B ARMS2 AXIN2 BCKDK C12orf48 CACFD1 CDK5RAP3 CDK6 CEP120 CHMP1A CRIPAK CTA-85E5.10 CTB-36H16.2 CYBRD1 DCAF16 DCXR DDX42 DIRAS3 DLEU2 DLG1 E2F1 EBPL EML3 EYA2 FHL3 GNA12 GPR126 GSDMC H1FX HSD3B7 IPO8 JAG1 KANSL1 LIME1 LOC644172 LRRC37A LRRC37A2 MRGPRF NCAPG NCOA1 NDST2 NOA1 NOV PIP4K2B PLCD3 PLEKHM1P RP11-435O5.4 RP11-435O5.5 RP11-73O6.3 RP11-967K21.1 RP5-966M1.6 RPL10A RPS20 SCMH1 SMARCD2 SNAI3-AS1 TBX6 TNFAIP8L3 TPCN2 TULP4 WHAMM WNT4 ZBTB38 ZCCHC24 ZNF169 ZNF438 ZNF76
BMI 2.6 55 34 75.6 -0.61 6.2e-08 AAGAB AC092667.2 ADCY3 ANKRD13B AP3B1 ARFGEF2 ATP13A2 BCKDK C1QTNF4 CCDC171 CCDC47 CDK5RAP3 CEP120 CLEC18A CMIP CXCR2 DCAF16 DDX27 DDX42 DLG1 EDNRB EIF2AK4 FOXP1 GSK3A HABP4 HSD3B7 LOXL1-AS1 MFSD10 MST1L MST1P2 MYO9A NFAT5 NOB1 NOP58 NUDC NUDT3 OTUD4 PACSIN1 PDXDC2 PIAS4 PIGF PTRHD1 RNF123 RP11-179B2.2 RP11-443B20.1 RP11-538P18.2 RP11-73O6.3 RP5-966M1.6 RPL10A SAR1B SMARCD2 TBX6 TMED6 VKORC1 ZFAS1
Height 10.9 218 206 457.8 0.92 9.9e-105 AAGAB ABO AC103965.1 ACPL2 ADAMTS6 ADCY3 AHI1 ANAPC10 ANKRD13B ANKRD9 AOC1 AP000580.1 AP3B1 ARFGEF2 ARMS2 ATP13A2 ATP5G1 AXIN2 BCKDHB BOK BRAF C10orf11 C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 C2orf54 C9orf3 CACFD1 CAMLG CCDC126 CCDC47 CCDC87 CD79B CDC123 CDK6 CDO1 CENPW CEP120 CHMP1A CLEC18A CLK3 CLUAP1 CMIP COG4 CRIPAK CROCC CSE1L CTA-85E5.10 CTC-228N24.3 CTD-3074O7.12 CTD-3074O7.5 CTD-3076O17.1 CXCR2 CYB561 CYBRD1 DCAF16 DCXR DDX27 DDX42 DHDDS DIRAS3 DLEU2 DLG5 DNAJC9-AS1 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 ERC1 ERCC6L2 ESPNP FAM136A FAM26F FER FEZ2 FHL3 FILIP1 FNDC3B GDF5 GNA12 GPR126 GSDMC GSK3A H1FX HABP4 HAPLN3 HORMAD2 HP IGFBP3 ILF3-AS1 IPO8 JAG1 KANSL1 KCNK7 KLHL7 LDHA LEMD3 LIME1 LMCD1 LOC285733 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 MAP3K1 MFGE8 MFSD10 MGC57346 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTERFD2 MTMR3 MTTP MYO1F MYO9A NARFL NCAPG NCOA1 NDUFB2 NFAT5 NMBR NOA1 NOB1 NOP58 NOV NUDC NUDT3 OTUD4 PACSIN1 PASK PDXDC2 PIAS4 PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 PTRHD1 QSOX2 RAB24 RAD9A RCN2 RNF40 RP11-1055B8.4 RP11-108M9.5 RP11-109N23.6 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-538P18.2 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RP11-977G19.11 RP5-966M1.6 RPL10A RPS20 RPS6KA1 RPS6KB2 SAR1B SCMH1 SEP15 SEPT2 SERPINF1 SF3B2 SHKBP1 SIK3 SLC25A21 SLC38A2 SLCO1C1 SMARCD2 SNAI3-AS1 SNRPD2 SURF1 SUSD5 TBX6 TCP11 TEAD3 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 USP14 WAC-AS1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF169 ZNF213 ZNF500 ZNF76
Waist Hip Ratio (WHR) 2.3 45 24 53.3 -0.20 1.7e-01 AAGAB AC103965.1 ADCY3 ANAPC10 AP3B1 ARL17B ATP13A2 BCKDHB C12orf48 CD79B CENPW CLUAP1 CROCC DCXR EBPL EML3 EYA2 GDF5 KANSL1 LOC644172 LRRC37A LRRC37A2 LRRC37A4 MGC57346 MST1L MST1P2 MYO1F NCOA1 NFAT5 OTUD4 PIP4K2B PLK1S1 PRPS1P2 RAB24 RAD9A RP11-108M9.5 RP11-182J1.14 RP11-73O6.3 SF3B2 SNRPD2 TNFAIP8L3 TPCN2 UIMC1 WNT4 ZBTB38
Systolic Blood Pressure 1.7 32 24 53.3 -0.38 1.1e-02 ACPL2 ADCY3 ARFGEF2 ATP5G1 C12orf48 CDC123 CDK6 CEP120 CYBRD1 DCAF16 DOK7 EFEMP1 FER FHL3 GDF5 LOC285733 LRRC37A2 NCAPG NCOA1 NOV PLEKHM1P PTRHD1 RIN3 RP11-1055B8.4 RP11-179B2.2 RP11-443B20.1 RP11-538P18.2 RPL10A TEAD3 ZFAS1 ZMAT2 ZNF500
Smoking Status 1.4 7 3 6.7 -0.45 2.6e-01 FOXP1 LRRC37A2 NOB1 PDXDC2 PRPS1P2 RP5-966M1.6 TMEM180
Allergy or Eczema 1.3 7 4 8.9 -0.12 7.8e-01 AAGAB AHI1 CXCR2 LIME1 PACSIN1 TMEM180 ZBTB38
Cardiovascular Disease 1.6 16 6 13.3 -0.71 6.7e-04 AAGAB ADCY3 ATP5G1 BCKDK CDK6 DCAF16 DDX42 HSD3B7 MFSD10 NCAPG NCOA1 NOP58 RP11-1055B8.4 RP11-538P18.2 SMARCD2 VKORC1
Hypothyroidism (self reported) 1.3 7 5 11.1 -0.22 6.4e-01 AHI1 ARMS2 HORMAD2 MTMR3 PLEKHA1 SEPT2 SIK3
Respiratory disease 1.7 7 3 6.7 -0.67 6.7e-02 AAGAB AHI1 CTD-3074O7.12 LIME1 NOA1 ZNF169 ZNF76
Type 2 Diabetes (T2D) (2018) 1.5 5 1 2.2 -0.30 6.2e-01 CENPW CLEC18A DMPK MAN2C1 NOB1
Lung FEV1/FVC ratio 4.7 61 45 100.0 -0.44 9.3e-05 ABLIM3 AC103965.1 ADCY3 ANKRD13B ARMS2 ATP13A2 C10orf11 CCDC171 CDC123 CDK5RAP3 CENPW CEP120 CROCC CTA-85E5.10 CTC-228N24.3 DNAJC9-AS1 DRAM1 EFEMP1 EIF2AK4 ERC1 FEZ2 GDF5 GNA12 GPR126 HSD3B7 INTS12 LMCD1 LOXL1-AS1 LRRC37A MST1L MST1P2 MTERFD2 MYO1F NCOA1 NDST2 NMBR NOA1 NOV OTUD4 PIP4K2B PLEKHA1 PLEKHM1P PPA2 PSMA4 PTCH1 PTRHD1 RCN2 RP11-108M9.5 RP11-182J1.14 RP11-435O5.5 RP11-443B20.1 RPL10A RPS20 SEPT2 SHKBP1 TCP11 TEAD3 WHAMM ZBTB38 ZFAS1 ZNF76
Lung FVC 6.2 145 112 248.9 0.89 6.8e-60 AAGAB ABLIM3 ABO AC073834.3 AC092667.2 AHI1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARL17B ARMS2 ATP13A2 BCKDK BCL7C BOK BRAF C10orf11 C12orf48 C2orf54 C9orf3 CACFD1 CCDC126 CCDC171 CCDC87 CD79B CDC123 CDK5RAP3 CENPW CEP120 CLEC18A CLUAP1 COG4 CROCC CTA-85E5.10 CTB-36H16.2 CTC-228N24.3 DARS DCAF16 DCXR DDX27 DHDDS DIRAS3 DLG1 DOK7 EBPL EFEMP1 EIF2AK4 EML3 ERC1 EYA2 FAM136A FAM26F FEZ2 FOXP1 GALNT12 GDF5 GSDMC GSK3A HMBS HORMAD2 HSD3B7 INTS12 IPO8 JAG1 KANSL1 KCNK7 LIME1 LMCD1 LOC285733 LOC644172 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 LRRC37A4 MAN2C1 MFSD10 MGC57346 MIR4519 MST1L MST1P2 NCAPG NCOA1 NDST2 NDUFB2 NFAT5 NOA1 NOB1 NOP58 NOV PDXDC2 PLCD3 PLEKHM1P PLK1S1 PPA2 PSMA4 PTCH1 QSOX2 RAD9A RIN3 RNF123 RP11-1055B8.4 RP11-108M9.5 RP11-425D10.10 RP11-435O5.5 RP11-538P18.2 RP11-73O6.3 RP11-967K21.1 RP11-977G19.11 RPL10A RPS20 RPS6KA1 RPS6KB2 SAR1B SCMH1 SEP15 SEPT2 SF3B2 SHKBP1 SHROOM3 SIK3 SLC25A21 SLC38A2 SNAI3-AS1 STX1B STX4 SURF1 SUSD5 TCP11 TCP11L1 TEAD3 TRIM63 TULP4 UBXN2A USP14 VKORC1 WHAMM WNT4 ZBTB38 ZFAS1 ZMAT2 ZNF213 ZNF438 ZNF500
Neuroticism 1.9 14 9 20.0 -0.39 1.3e-01 AAGAB ARL17B BCL7C CENPW HORMAD2 HSD3B7 KANSL1 LRRC37A LRRC37A2 MGC57346 PRPS1P2 PTCH1 STX1B STX4
Chronotype (morning person) 1.2 1 1 2.2 0.00 1.0e+00 CYB561
Hair Pigment 1.8 24 22 48.9 -0.12 5.5e-01 ADCY3 ARL17B BRAF CCDC87 CHMP1A DCXR E2F1 EDNRB FAM136A GDF5 HMBS KANSL1 LRRC37A MRGPRF NOA1 RP11-73O6.3 RPS6KB2 SLC38A2 SNAI3-AS1 TP53INP2 TPCN2 TULP4 ZBTB38 ZNF76
Tanning 1.3 8 7 15.6 0.58 8.0e-02 ADCY3 CHMP1A E2F1 GDF5 RP11-443B20.1 RP5-966M1.6 SNAI3-AS1 TP53INP2
Hand grip strength (left) 4.6 46 26 57.8 0.97 3.3e-39 ADCY3 AOC1 AP000580.1 ARFGEF2 AXIN2 BRAF C12orf48 C1QTNF4 CCDC87 CD79B CHMP1A CLEC18A CTD-3074O7.12 CYB561 DARS DCAF16 DLG5 FER FOXP1 GDF5 H1FX JAG1 KANSL1 LOXL1-AS1 LRRC37A LRRC37A2 NCAPG NCOA1 NOB1 PDXDC2 PIGF PIP4K2B PRPS1P2 PTRHD1 RAD9A RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 SLC38A2 TBX6 TCP11 TMEM180 TRA2A ZBTB38 ZCCHC24 ZNF500
Number of treatments/medications taken 1.6 2 0 0.0 0.00 1.0e+00 DCAF16 NCAPG
Sensitivity / hurt feelings 1.9 6 5 11.1 -0.68 6.3e-02 ARL17B KANSL1 LRRC37A LRRC37A2 MGC57346 PTCH1
Frequency of depressed mood in last 2 weeks 1.4 2 0 0.0 0.00 1.0e+00 LRRC37A2 ZFAS1
Hearing difficulty/problems: Yes 1.5 1 1 2.2 0.00 1.0e+00 ABLIM3
Relative age of first facial hair 2.0 9 5 11.1 -0.48 1.3e-01 ARL17B CHMP1A KANSL1 LEMD3 LRRC37A LRRC37A2 RP11-179B2.2 RP11-65J21.3 ZBTB38
Systolic blood pressure, automated reading 1.8 15 5 11.1 -0.44 5.3e-02 ADCY3 ATP5G1 CDK6 DCAF16 DOK7 EFEMP1 FER FHL3 LRRC37A2 NCAPG NOV PPA2 RP11-1055B8.4 RP11-538P18.2 ZNF500
Diabetes (mother) 1.6 1 0 0.0 0.00 1.0e+00 SNRPD2
Pack years adult smoking proportion 2.2 3 1 2.2 0.00 1.0e+00 CYB561 PIAS4 PSMA4
Impedance of leg (right) 2.4 46 28 62.2 -0.05 7.2e-01 ABO AC103965.1 ADCY3 AOC1 AP3B1 ATP13A2 CD79B CDK6 CDO1 CEP120 CRIPAK CROCC CTC-228N24.3 CTD-3074O7.5 CTD-3076O17.1 CYBRD1 EDNRB GDF5 H1FX LOXL1-AS1 MAP3K1 MRGPRF MST1L MST1P2 MTERFD2 NDST2 NUDT3 OTUD4 PACSIN1 PASK PTCH1 RAD9A RIN3 RP11-108M9.5 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 RPS20 SLC38A2 SNAI3-AS1 TBX6 TCP11L1 WNT4
Leg fat-free mass (left) 5.2 98 73 162.2 0.92 2.4e-48 ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DDX42 DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LOXL1-AS1 MFGE8 MPHOSPH6 MRGPRF MRPL42 MYO1F NARFL NCAPG NMBR NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.5 RP11-73O6.3 RPL10A RPS20 SCMH1 SEPT2 SLC38A2 SMARCD2 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF500 ZNF76
Trunk fat percentage 2.5 35 27 60.0 -0.24 1.4e-01 AAGAB AC103965.1 ADCY3 AP3B1 ARFGEF2 BCKDK C1QTNF4 CCDC171 CENPW CLEC18A CTD-3076O17.1 DARS DLG1 EFEMP1 EML3 FEZ2 FOXP1 GNA12 HSD3B7 LIME1 LRRC37A2 NOB1 OTUD4 PACSIN1 PASK PIAS4 PTRHD1 RAD9A RIN3 RP11-182J1.14 RP11-443B20.1 STX1B TEAD3 VKORC1 ZBTB38
Hand grip strength (right) 4.7 43 26 57.8 0.96 1.2e-33 ACPL2 ADCY3 AOC1 AP000580.1 ARFGEF2 AXIN2 C12orf48 C1QTNF4 CD79B CLEC18A CRIPAK CYB561 CYBRD1 DARS DCAF16 DLG5 GDF5 H1FX HABP4 JAG1 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 NCAPG NCOA1 NOB1 PDXDC2 PIP4K2B PLCD3 PRPS1P2 PTRHD1 RAD9A RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 SCMH1 TBX6 TMEM180 TRA2A TULP4 ZBTB38 ZCCHC24
Townsend deprivation index at recruitment 1.2 2 0 0.0 0.00 1.0e+00 BCKDK GPR126
Current tobacco smoking 1.2 2 2 4.4 0.00 1.0e+00 LIME1 PRPS1P2
Fed-up feelings 1.4 4 3 6.7 -0.94 1.8e-02 HORMAD2 KANSL1 LRRC37A LRRC37A2
Relative age voice broke 1.8 6 4 8.9 -0.86 1.2e-02 ARL17B KANSL1 LRRC37A LRRC37A2 RP11-65J21.3 SCMH1
Taking other prescription medications 1.3 1 0 0.0 0.00 1.0e+00 AHI1
Age when periods started (menarche) 2.0 12 8 17.8 0.51 4.3e-02 ADCY3 C1QTNF4 CAMLG CENPW CLEC18A NFAT5 NOB1 PDXDC2 RP11-179B2.2 RP11-65J21.3 SAR1B SCMH1
Bilateral oophorectomy (both ovaries removed) 1.2 1 1 2.2 0.00 1.0e+00 WNT4
Heel bone mineral density (BMD) T-score, automated (left) 2.0 12 7 15.6 -0.48 5.8e-02 CDK6 CRIPAK DLEU2 EBPL FHL3 JAG1 MRGPRF RP11-435O5.5 TPCN2 WNT4 ZNF169 ZNF438
Qualifications: CSEs or equivalent 1.2 1 0 0.0 0.00 1.0e+00 KANSL1
High blood pressure 1.5 8 4 8.9 -0.32 3.4e-01 ADCY3 BCKDK DCAF16 LRRC37A2 NCAPG NCOA1 PIAS4 RP11-538P18.2
Hayfever, allergic rhinitis or eczema 1.1 4 3 6.7 -0.30 6.2e-01 AHI1 LIME1 TMEM180 ZBTB38
Medication: Levothyroxine sodium 1.1 2 1 2.2 0.00 1.0e+00 HORMAD2 SEPT2
Sitting height 9.6 174 150 333.3 0.93 1.2e-88 ABO AC073834.3 AC103965.1 ACPL2 ADCY3 ANAPC10 AOC1 AP3B1 ARFGEF2 ARL17B ATP13A2 ATP5G1 AXIN2 BCKDHB BOK C12orf60 C1QTNF4 C20orf199 C2orf52 C9orf3 CAMLG CCDC126 CCDC171 CCDC47 CD79B CDK6 CDO1 CENPW CEP120 CHMP1A CLEC18A CLK3 CMIP COG4 CRIPAK CROCC CSE1L CTD-3076O17.1 CXCR2 CYBRD1 DCAF16 DCXR DDX27 DDX42 DHDDS DLEU2 DLG5 DMPK DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 ERC1 ERCC6L2 ESPNP EYA2 FAM136A FAM26F FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC GSK3A H1FX HABP4 HAPLN3 HORMAD2 IGFBP3 ILF3-AS1 JAG1 KANSL1 KCNK7 KLHL7 LEMD3 LOC644172 LOXL1-AS1 LRRC37A LRRC37A2 LRRC37A4 MAN2C1 MAP3K1 MFGE8 MGC57346 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTERFD2 MTMR3 MTTP MYO1F MYO9A NARFL NCAPG NCOA1 NFAT5 NMBR NOB1 NOV NUDC NUDT3 OTUD4 PACSIN1 PASK PDXDC2 PIGF PIP4K2B PLCD3 PLEKHA1 PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 PTRHD1 QSOX2 RAB24 RAD9A RCN2 RP11-1055B8.4 RP11-108M9.5 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-538P18.2 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RP11-967K21.1 RP5-966M1.6 RPL10A RPS20 RPS6KA1 RSPH6A SAR1B SCMH1 SEPT2 SERPINF1 SLC25A21 SLC38A2 SMARCD2 SNAI3-AS1 SNRPD2 SURF1 TBX6 TEAD3 TMED6 TMEM180 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 TULP4 UBXN2A WAC-AS1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF169 ZNF76
Chronic bronchitis/emphysema (father) 1.5 1 1 2.2 0.00 1.0e+00 PSMA4
Body mass index (BMI) 2.5 34 19 42.2 -0.60 3.9e-05 AC092667.2 ADCY3 AP3B1 ARFGEF2 ATP13A2 BCKDK C1QTNF4 CCDC171 CCDC87 CDK5RAP3 CEP120 CLEC18A CXCR2 DCAF16 FOXP1 HSD3B7 NOB1 NUDC NUDT3 OTUD4 PACSIN1 PDXDC2 PIAS4 PIGF PTRHD1 RP11-179B2.2 RP11-443B20.1 RP5-966M1.6 RPL10A SAR1B TBX6 TMED6 VKORC1 ZFAS1
Impedance of leg (left) 2.4 49 28 62.2 0.07 5.9e-01 ABO AC103965.1 ADCY3 AOC1 AP3B1 ATP13A2 CD79B CDO1 CEP120 CHMP1A CROCC CTC-228N24.3 CTD-3074O7.12 CTD-3074O7.5 CTD-3076O17.1 CXCR2 CYBRD1 EDNRB GDF5 GPR126 H1FX KANSL1 LOXL1-AS1 LRRC37A2 MAP3K1 MRGPRF MST1L MST1P2 MTERFD2 NDST2 NUDT3 OTUD4 PACSIN1 PASK PPA2 PTCH1 RAD9A RIN3 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 RPS20 SEPT2 SLC38A2 TBX6 WNT4
Leg predicted mass (left) 5.2 98 73 162.2 0.92 6.1e-49 ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DDX42 DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LOXL1-AS1 MFGE8 MPHOSPH6 MRGPRF MRPL42 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.5 RP11-73O6.3 RPL10A RPS20 SCMH1 SEPT2 SLC38A2 SMARCD2 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF500 ZNF76
Trunk fat mass 2.6 43 33 73.3 0.35 1.4e-02 AAGAB AC103965.1 ADCY3 ANAPC10 AP3B1 BCKDK C1QTNF4 CCDC171 CDK6 CEP120 CLEC18A CTD-3076O17.1 DLG1 E2F1 EFEMP1 EIF2AK4 FEZ2 FOXP1 GDF5 GNA12 GPR126 H1FX HAPLN3 HSD3B7 LIME1 LRRC37A2 NOB1 OTUD4 PACSIN1 PIAS4 PLEKHA1 RAD9A RP11-179B2.2 RP11-182J1.14 RP11-443B20.1 RP11-73O6.3 RPL10A STX1B TBX6 TP53INP2 VKORC1 ZBTB38 ZNF500
Waist circumference 2.1 27 22 48.9 -0.11 5.6e-01 AAGAB AC092667.2 ADCY3 AP3B1 BCKDK C1QTNF4 CCDC171 CDK5RAP3 CDK6 CEP120 CLEC18A HSD3B7 LIME1 NOB1 NUDT3 OTUD4 PACSIN1 PIAS4 RAD9A RP11-179B2.2 RP11-443B20.1 RPL10A SAR1B STX1B TBX6 VKORC1 ZBTB38
Number of incorrect matches in round 1.7 3 2 4.4 0.00 1.0e+00 BCKDK TBX6 VKORC1
Past tobacco smoking 1.4 5 1 2.2 0.52 3.7e-01 NOA1 NOB1 PRPS1P2 RP11-977G19.11 TMEM180
Alcohol usually taken with meals 1.3 1 1 2.2 0.00 1.0e+00 FOXP1
Nervous feelings 1.5 6 1 2.2 -0.82 2.4e-02 CENPW CTA-85E5.10 LRRC37A LRRC37A2 RP5-966M1.6 TBX6
Frequency of tenseness / restlessness in last 2 weeks 1.4 4 2 4.4 -1.00 2.1e-04 ARL17B KANSL1 LRRC37A LRRC37A2
Hearing difficulty/problems with background noise 1.4 1 0 0.0 0.00 1.0e+00 LRRC37A2
Hair/balding pattern: Pattern 2 1.3 2 2 4.4 0.00 1.0e+00 C10orf11 LRRC37A2
Had other major operations 1.2 1 0 0.0 0.00 1.0e+00 PPA2
Heel bone mineral density (BMD) T-score, automated (right) 2.0 16 8 17.8 -0.56 1.7e-02 CDK6 CRIPAK DCAF16 DLEU2 EBPL FHL3 MRGPRF NCAPG NOA1 RP11-435O5.5 TPCN2 WNT4 ZBTB38 ZNF169 ZNF438 ZNF76
Ever unenthusiastic/disinterested for a whole week 1.4 2 0 0.0 0.00 1.0e+00 KANSL1 ZMAT2
Qualifications: None of the above 1.3 4 0 0.0 -0.98 2.1e-02 ATP5G1 FOXP1 PPA2 RNF123
Allergy 1.3 9 6 13.3 0.29 4.2e-01 AAGAB ABO AHI1 AP000580.1 CTD-3074O7.12 CTD-3074O7.5 LIME1 TMEM180 ZBTB38
Diabetes (self-reported) 1.6 2 0 0.0 0.00 1.0e+00 CLUAP1 MAN2C1
Medication: Simvastatin 1.6 2 1 2.2 0.00 1.0e+00 ABO DCAF16
Fluid intelligence score 1.8 8 2 4.4 0.89 2.9e-04 C1QTNF4 CSE1L DCAF16 FOXP1 NCAPG PPA2 RNF123 U91328.21
Illnesses of siblings 1.6 2 0 0.0 0.00 1.0e+00 BCKDK VKORC1
Neuroticism score 1.7 11 9 20.0 -0.29 3.4e-01 ARL17B BCL7C HORMAD2 HSD3B7 KANSL1 LRRC37A LRRC37A2 MGC57346 PTCH1 STX1B STX4
Weight 3.7 73 52 115.6 0.75 8.0e-17 AAGAB AC103965.1 ADCY3 ANAPC10 AP3B1 ARMS2 BCKDHB BCKDK BOK C12orf60 CCDC171 CD79B CDK6 CENPW CEP120 CRIPAK CTD-3076O17.1 CYBRD1 DCAF16 DDX42 DLEU2 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 GDF5 GNA12 GPR126 H1FX HAPLN3 HORMAD2 HSD3B7 ILF3-AS1 LIME1 MPHOSPH6 MRGPRF MRPL42 MYO1F NARFL NCAPG NMBR NUDT3 OTUD4 PACSIN1 PLEKHA1 PPA2 RAD9A RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-435O5.5 RP11-443B20.1 RP11-73O6.3 RPL10A RPS20 SCMH1 SEPT2 SERPINF1 SLC38A2 TBX6 TCP11 TEAD3 TMEM180 TP53INP2 TRA2A VKORC1 WNT4 ZBTB38 ZCCHC24 ZNF500 ZNF76
Impedance of arm (right) 2.1 41 29 64.4 0.16 2.8e-01 AAGAB AC103965.1 AOC1 ATP13A2 BCKDK CD79B CENPW CEP120 CRIPAK CTD-3076O17.1 CYBRD1 EFEMP1 EML3 FER FEZ2 GPR126 LOXL1-AS1 LRPAP1 LRRC37A2 MFGE8 MRPL42 MST1L MST1P2 MTERFD2 NUDT3 PACSIN1 PASK PLK1S1 RIN3 RP11-108M9.5 RP11-179B2.2 RP11-182J1.14 RP11-73O6.3 RP5-966M1.6 RPL10A RPS20 SAR1B SCMH1 SLC38A2 TBX6 VKORC1
Arm fat percentage (right) 3.0 37 24 53.3 -0.80 3.9e-11 AAGAB ABO ADCY3 ANKRD13B AP3B1 ARFGEF2 BCKDK C1QTNF4 CCDC171 CCDC87 CD79B CDK5RAP3 CENPW CLEC18A CTD-3074O7.12 CTD-3074O7.5 DCAF16 DDX27 DLG1 FOXP1 HABP4 HSD3B7 LIME1 NCAPG NOB1 NOP58 NOV PDXDC2 PIAS4 PIGF PTRHD1 RP11-443B20.1 SAR1B TBX6 TEAD3 VKORC1 ZFAS1
Trunk fat-free mass 7.3 128 98 217.8 0.93 7.9e-67 ACPL2 ADCY3 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP13A2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 C9orf3 CCDC47 CD79B CDK6 CENPW CEP120 CHMP1A CRIPAK CSE1L CXCR2 CYB561 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FAM136A FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MST1L MTMR3 MYO1F MYO9A NARFL NCAPG NCOA1 NDUFB2 NMBR NOA1 NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 PTRHD1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SAR1B SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SNAI3-AS1 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF213 ZNF500 ZNF76
Hip circumference 3.0 53 35 77.8 0.44 5.3e-04 AC103965.1 ADCY3 ANAPC10 AP3B1 BCKDK BCL7C BOK C1QTNF4 C2orf54 CCDC171 CD79B CDK6 CEP120 CLEC18A CYBRD1 DLEU2 E2F1 EFEMP1 EIF2AK4 EYA2 FEZ2 GDF5 GNA12 GPR126 H1FX HSD3B7 LIME1 NARFL NOB1 NUDT3 OTUD4 PACSIN1 PLEKHA1 RAD9A RP11-179B2.2 RP11-182J1.14 RP11-435O5.5 RP11-443B20.1 RP11-73O6.3 RPL10A RPS20 SCMH1 SEPT2 SLC38A2 STX1B STX4 TBX6 TEAD3 TP53INP2 TPCN2 VKORC1 WNT4 ZBTB38
Father's age at death 1.2 1 1 2.2 0.00 1.0e+00 PSMA4
Worrier / anxious feelings 1.6 6 3 6.7 -0.12 8.0e-01 HSD3B7 LRRC37A2 PTCH1 RP5-966M1.6 STX1B TMEM180
Frequency of tiredness / lethargy in last 2 weeks 1.4 3 0 0.0 0.00 1.0e+00 ATP5G1 DDX27 ZFAS1
Hair/balding pattern: Pattern 3 2.1 6 5 11.1 0.71 7.2e-02 ARL17B CENPW KANSL1 LOC644172 LRRC37A LRRC37A2
Number of live births 1.2 2 1 2.2 0.00 1.0e+00 LRRC37A WNT4
Forced expiratory volume in 1-second (FEV1) 10.3 205 154 342.2 0.98 1.3e-181 ABLIM3 ABO AC073834.3 AC092667.2 AC103965.1 ADAMTS6 ADCY3 AHI1 ANAPC10 AOC1 AP000580.1 AP3B1 ARFGEF2 ARL17B ATP13A2 AXIN2 BCKDHB BCKDK BCL7C BOK BRAF C10orf11 C12orf48 C12orf60 C1QTNF4 C2orf52 CACFD1 CAMLG CCDC126 CCDC171 CCDC87 CD79B CDC123 CDK6 CDO1 CENPW CEP120 CHMP1A CLEC18A CLK3 CLUAP1 CMIP COG4 CRIPAK CTA-85E5.10 CTB-36H16.2 CTD-3074O7.12 CTD-3074O7.5 CTD-3076O17.1 CXCR2 CYB561 CYBRD1 DARS DCAF16 DCXR DDX27 DDX42 DHDDS DIRAS3 DLEU2 DLG1 DLG5 DNAJC9-AS1 DOK7 EBPL EFEMP1 EIF2AK4 EML3 ERCC6L2 EYA2 FAM136A FAM26F FAM35A FER FHL3 FILIP1 FNDC3B FOXP1 GALNT12 GDF5 GSDMC GSK3A H1FX HABP4 HAPLN3 HMBS HORMAD2 HP HSD3B7 IGFBP3 ILF3-AS1 INTS12 IPO8 JAG1 KANSL1 KIAA1468 LDHA LEMD3 LIME1 LOC285733 LOC644172 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 LRRC37A4 MAN2C1 MAP3K1 MFGE8 MFSD10 MGC57346 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTMR3 MTTP MYO9A NARFL NCAPG NCOA1 NDST2 NFAT5 NOA1 NOB1 NOV NUDC NUDT3 OTUD4 PACSIN1 PDXDC2 PIAS4 PLCD3 PLEKHM1P PNKD PPA2 PRPS1P2 PSMA4 PTCH1 QSOX2 RAB24 RAD9A RIN3 RNF123 RP11-1055B8.4 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-538P18.2 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RP11-967K21.1 RP5-966M1.6 RPL10A RPS20 RPS6KA1 RPS6KB2 RSPH6A SAR1B SCMH1 SERPINF1 SF3B2 SLC25A21 SLC38A2 SLCO1C1 SMARCD2 SNAI3-AS1 STX1B STX4 SURF1 SUSD5 TCP11 TCP11L1 TEAD3 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 TULP4 U91328.21 UBXN2A VKORC1 WAC-AS1 WHAMM WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF169 ZNF213 ZNF438 ZNF500 ZNF76
Pulse rate 1.2 2 2 4.4 0.00 1.0e+00 CEP120 ZBTB38
Happiness 1.2 1 0 0.0 0.00 1.0e+00 ZFAS1
Qualifications: A levels/AS levels or equivalent 1.4 4 0 0.0 0.94 6.2e-02 DCAF16 GDF5 LRRC37A2 RNF123
Mouth/teeth dental problems: Dentures 1.4 3 0 0.0 0.00 1.0e+00 ADCY3 PSMA4 RP11-1055B8.4
Asthma 1.7 5 3 6.7 -0.67 1.4e-01 AAGAB AHI1 CTD-3074O7.12 U91328.21 ZNF76
Medication: Ibuprofen (e.g. Nurofen) 1.3 1 0 0.0 0.00 1.0e+00 U91328.21
Medication: Cholesterol lowering 1.6 3 1 2.2 0.00 1.0e+00 ABO HP NOP58
Lung cancer (father) 1.3 1 1 2.2 0.00 1.0e+00 PSMA4
Illnesses of mother 1.3 1 0 0.0 0.00 1.0e+00 ATP5G1
Forced expiratory volume in 1-second (FEV1), Best measure 9.8 180 115 255.6 0.98 1.8e-154 ABLIM3 ABO AC073834.3 AC092667.2 AC103965.1 ADAMTS6 ADCY3 AHI1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARL17B ATP13A2 AXIN2 BCKDHB BCKDK BCL7C BOK BRAF C10orf11 C12orf48 C12orf60 C1QTNF4 C2orf52 C2orf54 CACFD1 CAMLG CCDC87 CD79B CDC123 CDK6 CDO1 CENPW CEP120 CLEC18A CLK3 CLUAP1 CMIP COG4 CRIPAK CTA-85E5.10 CTB-36H16.2 CTD-3074O7.12 CTD-3076O17.1 CXCR2 CYB561 CYBRD1 DARS DCAF16 DCXR DDX27 DDX42 DHDDS DIRAS3 DLEU2 DLG1 DLG5 DNAJC9-AS1 EBPL EFEMP1 EML3 ERCC6L2 FAM136A FAM26F FER FEZ2 FHL3 FILIP1 FNDC3B FOXP1 GALNT12 GDF5 GSDMC GSK3A H1FX HABP4 HAPLN3 HORMAD2 HSD3B7 ILF3-AS1 INTS12 IPO8 JAG1 KANSL1 KIAA1468 LEMD3 LIME1 LOC285733 LOC644172 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 LRRC37A4 MAN2C1 MGC57346 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTMR3 MTTP MYO1F MYO9A NCAPG NCOA1 NDST2 NFAT5 NOA1 NOB1 NUDC OTUD4 PACSIN1 PDXDC2 PIAS4 PLCD3 PLEKHM1P PNKD PPA2 PSMA4 QSOX2 RAB24 RAD9A RIN3 RNF123 RP11-1055B8.4 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-443B20.1 RP11-538P18.2 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RP11-967K21.1 RP11-977G19.11 RP5-966M1.6 RPL10A RPS20 RPS6KA1 SAR1B SCMH1 SERPINF1 SHKBP1 SLC25A21 SLC38A2 SMARCD2 SNAI3-AS1 STX1B STX4 TCP11 TCP11L1 TEAD3 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 U91328.21 UBXN2A VKORC1 WAC-AS1 WHAMM WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF169 ZNF213 ZNF438 ZNF500 ZNF76
Impedance of arm (left) 2.1 42 28 62.2 0.26 7.5e-02 AC103965.1 AOC1 ATP13A2 BCKDK CD79B CENPW CEP120 CTD-3076O17.1 EFEMP1 EML3 FER FEZ2 GNA12 GPR126 KANSL1 LOXL1-AS1 LRRC37A LRRC37A2 MAP3K1 MFGE8 MGC57346 MRPL42 MST1L MST1P2 MTERFD2 NUDT3 PACSIN1 PASK PLK1S1 RIN3 RP11-108M9.5 RP11-179B2.2 RP11-182J1.14 RP11-73O6.3 RP5-966M1.6 RPL10A RPS20 SAR1B SCMH1 SHKBP1 SLC38A2 TBX6
Arm fat mass (right) 2.2 30 22 48.9 -0.13 4.7e-01 AAGAB AC092667.2 ADCY3 AP3B1 BCKDK C1QTNF4 CCDC171 CCDC87 CDK6 CEP120 CLEC18A FEZ2 FOXP1 HSD3B7 LIME1 NOB1 NUDT3 OTUD4 PACSIN1 PDXDC2 PIAS4 PTRHD1 RP11-179B2.2 RP11-443B20.1 RP11-73O6.3 RPL10A TBX6 TP53INP2 VKORC1 ZBTB38
Trunk predicted mass 7.3 126 99 220.0 0.94 2.5e-68 ACPL2 ADCY3 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP13A2 ATP5G1 AXIN2 BCKDHB BOK C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 C9orf3 CCDC47 CD79B CDK6 CENPW CEP120 CHMP1A CRIPAK CSE1L CXCR2 CYB561 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FAM136A FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MST1L MTMR3 MYO1F MYO9A NARFL NCAPG NCOA1 NDUFB2 NMBR NOA1 NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 PTRHD1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SNAI3-AS1 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF213 ZNF500 ZNF76
Standing height 10.7 197 173 384.4 0.94 8.2e-111 AAGAB AC103965.1 ACPL2 ADAMTS6 ADCY3 ANAPC10 ANKRD13B ANKRD9 AOC1 AP000580.1 AP3B1 ARFGEF2 ARMS2 ATP13A2 ATP5G1 AXIN2 BCKDHB BOK BRAF C12orf60 C1QTNF4 C20orf199 C2orf52 C9orf3 CAMLG CCDC126 CCDC47 CCDC87 CD79B CDK6 CDO1 CENPW CEP120 CHMP1A CLEC18A CLK3 CMIP COG4 CRIPAK CROCC CSE1L CTA-85E5.10 CTD-3074O7.12 CTD-3074O7.5 CTD-3076O17.1 CXCR2 CYB561 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DMPK DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 ERC1 ERCC6L2 ESPNP FAM136A FAM26F FAM35A FER FEZ2 FHL3 FILIP1 FNDC3B GDF5 GNA12 GPR126 GSDMC GSK3A H1FX HABP4 HAPLN3 HMBS HORMAD2 HP IGFBP3 ILF3-AS1 IPO8 JAG1 KCNK7 KIAA1468 KLHL7 LDHA LEMD3 LOC285733 LOXL1-AS1 LRRC37A2 MAN2C1 MAP3K1 MFGE8 MFSD10 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTERFD2 MTMR3 MTTP MYO1F MYO9A NARFL NCAPG NCOA1 NDUFB2 NFAT5 NMBR NOA1 NOB1 NOP58 NOV NUDC NUDT3 OTUD4 PACSIN1 PASK PDXDC2 PIAS4 PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 PTRHD1 QSOX2 RAB24 RAD9A RCN2 RNF40 RP11-1055B8.4 RP11-108M9.5 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-538P18.2 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RP11-977G19.11 RP5-966M1.6 RPL10A RPS20 RPS6KA1 RPS6KB2 SAR1B SCMH1 SEPT2 SERPINF1 SF3B2 SIK3 SLC25A21 SLC38A2 SLCO1C1 SMARCD2 SNAI3-AS1 SUSD5 TBX6 TCP11 TEAD3 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 WAC-AS1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZNF169 ZNF213 ZNF500 ZNF76
Breastfed as a baby 1.2 1 0 0.0 0.00 1.0e+00 RCN2
Tense / 'highly strung' 1.4 5 0 0.0 0.99 7.3e-04 BCKDK BCL7C HSD3B7 STX1B STX4
Seen doctor (GP) for nerves, anxiety, tension or depression 1.4 2 0 0.0 0.00 1.0e+00 CCDC87 U91328.21
Hair/balding pattern: Pattern 4 3.1 14 12 26.7 0.22 4.0e-01 ARL17B C10orf11 CENPW CTB-36H16.2 DLG5 FAM136A KANSL1 LOC285733 LOC644172 LRRC37A LRRC37A2 LRRC37A4 MGC57346 ZBTB38
Birth weight of first child 2.5 11 7 15.6 0.97 2.2e-09 ANAPC10 DCAF16 DCXR FEZ2 IPO8 OTUD4 PPA2 RPL10A TEAD3 WNT4 ZBTB38
Peak expiratory flow (PEF) 5.0 49 26 57.8 0.95 4.6e-29 ABO ANAPC10 ARFGEF2 ARL17B BOK C10orf11 C12orf48 CACFD1 CCDC87 CD79B CDC123 CLEC18A CTA-85E5.10 CTD-3074O7.12 DCAF16 DHDDS DLEU2 DLG1 EFEMP1 GDF5 GSDMC H1FX KANSL1 LRRC37A LRRC37A2 MPHOSPH6 MRGPRF NCAPG NOA1 OTUD4 PIAS4 PNKD PPA2 PRPS1P2 RAD9A RNF123 RP11-179B2.2 RP11-425D10.10 RP11-65J21.3 RPL10A RPS6KA1 SF3B2 TCP11 TCP11L1 TP53INP2 TRIM63 UBXN2A ZHX2 ZNF76
Qualifications: O levels/GCSEs or equivalent 1.3 1 0 0.0 0.00 1.0e+00 ZNF500
Blood clot in the leg (DVT) 1.5 2 2 4.4 0.00 1.0e+00 ABO CACFD1
Medication: Paracetamol 1.7 5 4 8.9 -0.64 1.7e-01 ARL17B KANSL1 LRRC37A LRRC37A2 U91328.21
Headache pain in last month 1.6 7 5 11.1 -0.75 3.3e-02 ARL17B KANSL1 LRRC37A LRRC37A2 MGC57346 NOA1 U91328.21
Hypothyroidism/myxoedema (self-reported) 1.2 6 3 6.7 -0.40 4.4e-01 AHI1 HORMAD2 MTMR3 PLEKHA1 SEPT2 SIK3
Medication: Ventolin 100micrograms inhaler 1.1 1 0 0.0 0.00 1.0e+00 AAGAB
Birth weight 2.8 19 7 15.6 0.90 2.4e-09 ANAPC10 C1QTNF4 CDK6 CENPW DCAF16 EDNRB GNA12 GPR126 HORMAD2 NCAPG PPA2 RP11-425D10.10 RP11-435O5.5 RP11-73O6.3 TEAD3 TRA2A TULP4 UBXN2A WNT4
Chronic bronchitis/emphysema (mother) 1.5 1 1 2.2 0.00 1.0e+00 PSMA4
High blood pressure (siblings) 1.5 1 1 2.2 0.00 1.0e+00 BCKDK
Forced vital capacity (FVC), Best measure 12.2 246 202 448.9 1.00 2.7e-321 AAGAB ABLIM3 ABO AC073834.3 AC092667.2 AC103965.1 ACPL2 ADAMTS6 ADCY3 AHI1 ANAPC10 ANKRD13B AOC1 AP000580.1 AP3B1 ARFGEF2 ARL17B ARMS2 ATP13A2 ATP5G1 AXIN2 BCKDHB BCKDK BCL7C BOK BRAF C10orf11 C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 C2orf54 C9orf3 CACFD1 CAMLG CCDC126 CCDC171 CCDC47 CCDC87 CD79B CDC123 CDK5RAP3 CDK6 CDO1 CENPW CEP120 CHMP1A CLEC18A CLK3 CLUAP1 CMIP COG4 CRIPAK CROCC CSE1L CTA-85E5.10 CTB-36H16.2 CTC-228N24.3 CTD-3074O7.12 CTD-3074O7.5 CTD-3076O17.1 CXCR2 CYB561 CYBRD1 DARS DCAF16 DCXR DDX27 DDX42 DHDDS DIRAS3 DLEU2 DLG1 DLG5 DMPK DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EML3 ERC1 ERCC6L2 ESPNP EYA2 FAM136A FAM26F FER FEZ2 FHL3 FILIP1 FNDC3B FOXP1 GALNT12 GDF5 GNA12 GPR126 GSDMC GSK3A H1FX HABP4 HAPLN3 HMBS HORMAD2 HP HSD3B7 ILF3-AS1 INTS12 IPO8 JAG1 KANSL1 KCNK7 KIAA1468 LDHA LEMD3 LIME1 LMCD1 LOC285733 LOC644172 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 LRRC37A4 MAN2C1 MFGE8 MGC57346 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTERFD2 MTMR3 MTTP MYO1F MYO9A NARFL NCAPG NCOA1 NDST2 NDUFB2 NFAT5 NMBR NOA1 NOB1 NOP58 NOV NUDC NUDT3 OTUD4 PACSIN1 PASK PDXDC2 PIAS4 PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PSMA4 PTCH1 PTRHD1 QSOX2 RAB24 RAD9A RCN2 RIN3 RNF123 RNF40 RP11-1055B8.4 RP11-108M9.5 RP11-109N23.6 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-538P18.2 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RP11-967K21.1 RP11-977G19.11 RP5-966M1.6 RPL10A RPS20 RPS6KA1 RPS6KB2 RSPH6A SAR1B SCMH1 SEPT2 SERPINF1 SF3B2 SHKBP1 SHROOM3 SIK3 SLC25A21 SLC38A2 SLCO1C1 SMARCD2 SNAI3-AS1 SNRPD2 STX1B STX4 SURF1 SUSD5 TBX6 TCP11 TCP11L1 TEAD3 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 U91328.21 UBXN2A UIMC1 USP14 VKORC1 WAC-AS1 WHAMM WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF169 ZNF213 ZNF438 ZNF500 ZNF76
Body fat percentage 2.7 38 23 51.1 -0.55 1.0e-04 AAGAB AC073834.3 AC103965.1 ADCY3 ANKRD13B AP3B1 ARFGEF2 BCKDK C1QTNF4 CCDC171 CD79B CENPW CLEC18A CTD-3076O17.1 DARS DCAF16 DLG1 EML3 FEZ2 FOXP1 HABP4 HMBS HSD3B7 LIME1 LRRC37A2 NOB1 NOV PIAS4 PTRHD1 RIN3 RP11-182J1.14 RP11-443B20.1 SAR1B STX1B TEAD3 VKORC1 ZBTB38 ZFAS1
Leg fat percentage (right) 3.0 46 26 57.8 -0.88 4.1e-18 AAGAB AC073834.3 ADCY3 ANKRD13B ARFGEF2 BCKDK BCL7C C1QTNF4 CCDC171 CD79B CDK5RAP3 CENPW CLEC18A CTC-228N24.3 DARS DCAF16 DDX27 DDX42 DLG1 FOXP1 GDF5 GSK3A HABP4 HMBS HSD3B7 LIME1 NCAPG NOB1 NOP58 NOV PIAS4 PIGF PLEKHM1P PTRHD1 RIN3 RP11-182J1.14 RP11-435O5.5 RP11-443B20.1 SAR1B SMARCD2 SNAI3-AS1 STX1B STX4 TEAD3 VKORC1 ZFAS1
Arm fat-free mass (right) 6.0 104 84 186.7 0.93 3.4e-54 ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 CD79B CDK6 CENPW CEP120 CHMP1A CRIPAK CXCR2 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F NARFL NCAPG NCOA1 NDUFB2 NMBR NOV NUDT3 OTUD4 PACSIN1 PLEKHA1 PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 UBXN2A UIMC1 VKORC1 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF76
Comparative body size at age 10 4.0 16 6 13.3 -0.78 1.7e-05 ADCY3 AP3B1 BCKDK C1QTNF4 CMIP DMPK ERCC6L2 HSD3B7 KANSL1 NCOA1 PTRHD1 RP11-443B20.1 STX1B U91328.21 UIMC1 VKORC1
Number of full brothers 1.2 1 0 0.0 0.00 1.0e+00 LRRC37A2
Worry too long after embarrassment 1.6 3 0 0.0 0.00 1.0e+00 AHI1 LRRC37A2 PPA2
Wheeze or whistling in the chest in last year 1.7 3 1 2.2 0.00 1.0e+00 CCDC171 LIME1 NDST2
Health satisfaction 1.1 1 0 0.0 0.00 1.0e+00 CCDC87
Qualifications: College or University degree 1.5 16 7 15.6 0.88 3.0e-06 DCAF16 DDX42 EML3 FOXP1 GDF5 HABP4 KANSL1 LOC644172 LRRC37A LRRC37A2 LRRC37A4 MFSD10 PPA2 RNF123 RP11-1055B8.4 SMARCD2
Medication for pain relief, constipation, heartburn 1.7 4 2 4.4 -0.56 3.3e-01 LRRC37A LRRC37A2 PLCD3 U91328.21
Medication: Blood pressure 1.4 1 0 0.0 0.00 1.0e+00 DCAF16
Mean time to correctly identify matches 1.4 4 0 0.0 0.66 3.4e-01 ARFGEF2 CSE1L DDX27 PIAS4
Whole body fat mass 2.4 40 28 62.2 0.23 1.3e-01 AAGAB AC103965.1 ADCY3 ANAPC10 AP3B1 BCKDK C1QTNF4 CCDC171 CDK6 CEP120 CLEC18A CTD-3076O17.1 DLG1 E2F1 EFEMP1 FEZ2 FOXP1 GDF5 GNA12 GPR126 H1FX HSD3B7 LIME1 LRRC37A2 NOB1 NUDT3 OTUD4 PACSIN1 PIAS4 PTRHD1 RAD9A RP11-179B2.2 RP11-182J1.14 RP11-443B20.1 RP11-73O6.3 RPL10A TBX6 TP53INP2 VKORC1 ZBTB38
Leg fat mass (right) 2.2 28 22 48.9 -0.13 4.9e-01 AAGAB ADCY3 AP3B1 BCKDK C1QTNF4 CCDC171 CDK6 CLEC18A DARS FOXP1 HSD3B7 LIME1 NOB1 NUDT3 OTUD4 PACSIN1 PIAS4 PTRHD1 RAD9A RP11-179B2.2 RP11-182J1.14 RP11-443B20.1 RP11-73O6.3 RPL10A SAR1B TBX6 VKORC1 ZBTB38
Arm predicted mass (right) 6.0 101 86 191.1 0.93 2.1e-52 ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CXCR2 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PLEKHA1 PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF76
Pulse rate, automated reading 1.5 13 6 13.3 -0.29 3.1e-01 AC103965.1 CEP120 DARS EML3 FNDC3B HABP4 MYO9A NCOA1 RNF40 RP11-1055B8.4 TRIM63 ZBTB38 ZNF500
Alcohol intake frequency. 1.5 10 7 15.6 -0.79 3.9e-03 AC092667.2 C1QTNF4 FOXP1 KANSL1 LRRC37A LRRC37A2 PPA2 TBX6 TMED6 UBXN2A
Comparative height size at age 10 9.0 145 122 271.1 0.95 2.8e-89 AAGAB AC103965.1 ACPL2 ADAMTS6 ADCY3 ANAPC10 ANKRD13B ANKRD9 AOC1 AP3B1 ARFGEF2 ARMS2 ATP13A2 ATP5G1 AXIN2 BCKDHB BOK C12orf48 C12orf60 C1QTNF4 C20orf199 CCDC126 CCDC47 CD79B CDK6 CDO1 CENPW CEP120 CHMP1A CMIP CRIPAK CROCC CSE1L CTA-85E5.10 CTD-3074O7.12 CTD-3074O7.5 CTD-3076O17.1 CXCR2 CYB561 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DMPK DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 ERCC6L2 ESPNP FAM136A FAM26F FER FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 IGFBP3 ILF3-AS1 KLHL7 LOXL1-AS1 LRRC37A2 MAN2C1 MAP3K1 MFGE8 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTMR3 MTTP MYO1F MYO9A NARFL NCAPG NCOA1 NMBR NOV OTUD4 PACSIN1 PIAS4 PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PNKD PPA2 PTCH1 PTRHD1 QSOX2 RAB24 RAD9A RP11-108M9.5 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-435O5.5 RP11-443B20.1 RP11-690I21.1 RP11-73O6.3 RP5-966M1.6 RPL10A RPS20 RPS6KA1 RPS6KB2 RSPH6A SCMH1 SEPT2 SERPINF1 SLC25A21 SMARCD2 SUSD5 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 U91328.21 UBXN2A UIMC1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZNF169 ZNF500 ZNF76
Suffer from 'nerves' 1.2 1 1 2.2 0.00 1.0e+00 C1QTNF4
Overall health rating 1.6 12 4 8.9 -0.94 8.1e-06 AP000580.1 BCKDK CCDC87 CTD-3074O7.12 CTD-3074O7.5 DCAF16 FOXP1 MFSD10 PRPS1P2 RP11-1055B8.4 SNRPD2 VKORC1
Family relationship satisfaction 1.3 1 0 0.0 0.00 1.0e+00 ZFAS1
Knee pain experienced in last month 1.6 1 1 2.2 0.00 1.0e+00 GDF5
Hypertension (Self-reported) 1.5 9 4 8.9 -0.40 2.0e-01 ADCY3 BCKDK DCAF16 LRRC37A2 NCAPG NCOA1 PIAS4 RP11-1055B8.4 RP11-538P18.2
Forced expiratory volume in 1-second (FEV1), predicted 7.2 64 39 86.7 0.97 2.4e-48 AC103965.1 ADCY3 ANAPC10 ATP13A2 ATP5G1 BOK C1QTNF4 CD79B CDK6 CENPW CTD-3076O17.1 CYBRD1 DCAF16 DDX42 DLEU2 E2F1 EBPL EFEMP1 ERCC6L2 FER FHL3 GDF5 GNA12 GPR126 GSDMC H1FX ILF3-AS1 LEMD3 LOXL1-AS1 MAN2C1 MFGE8 MRPL42 MST1L MST1P2 MYO1F MYO9A NARFL NCAPG OTUD4 PACSIN1 PIP4K2B PTCH1 RAB24 RAD9A RP11-182J1.14 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-73O6.3 RP11-977G19.11 RP5-966M1.6 RPL10A SCMH1 SMARCD2 TCP11 TEAD3 TMEM180 TP53INP2 TRA2A UIMC1 ZBTB38 ZHX2 ZNF500 ZNF76
Whole body fat-free mass 6.5 116 94 208.9 0.93 1.4e-59 ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 CCDC47 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CXCR2 CYB561 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MTMR3 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SNAI3-AS1 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF213 ZNF500 ZNF76
Leg fat-free mass (right) 5.3 102 74 164.4 0.92 1.4e-50 ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DDX42 DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MTMR3 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-73O6.3 RPL10A RPS20 SCMH1 SEPT2 SLC38A2 SMARCD2 SNAI3-AS1 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF500 ZNF76
Arm fat percentage (left) 3.0 36 26 57.8 -0.79 1.4e-10 AAGAB ABO ADCY3 ANKRD13B AP3B1 ARFGEF2 BCKDK C1QTNF4 CCDC171 CCDC87 CD79B CENPW CLEC18A CTD-3074O7.5 DCAF16 DDX27 DLG1 FOXP1 HABP4 HSD3B7 LIME1 NCAPG NFAT5 NOB1 NOP58 NOV PDXDC2 PIAS4 PIGF PTRHD1 RP11-443B20.1 SAR1B TBX6 TEAD3 VKORC1 ZFAS1
Average weekly red wine intake 1.2 1 1 2.2 0.00 1.0e+00 FOXP1
Handedness (chirality/laterality): Left-handed 1.3 1 1 2.2 0.00 1.0e+00 LRRC37A2
Mood swings 1.6 7 3 6.7 -0.86 6.7e-03 AP000580.1 ARL17B GPR126 KANSL1 LRRC37A LRRC37A2 RP11-179B2.2
Loneliness, isolation 1.5 4 0 0.0 0.98 1.7e-02 ARFGEF2 C1QTNF4 CSE1L DDX27
Long-standing illness, disability or infirmity 1.6 1 1 2.2 0.00 1.0e+00 CCDC171
Diabetes diagnosed by doctor 1.6 2 0 0.0 0.00 1.0e+00 CENPW CLEC18A
Qualifications: nursing, teaching 1.2 1 0 0.0 0.00 1.0e+00 AXIN2
Mouth/teeth dental problems: Mouth ulcers 1.5 4 2 4.4 -0.97 7.3e-03 ARL17B KANSL1 LRRC37A LRRC37A2
Medication for cholesterol 1.6 1 0 0.0 0.00 1.0e+00 ZNF500
Back pain experienced in last month 1.4 1 1 2.2 0.00 1.0e+00 ARMS2
Breast cancer (self-reported) 1.2 1 0 0.0 0.00 1.0e+00 KLHL7
Asthma (self-reported) 1.7 5 3 6.7 -0.65 1.6e-01 AAGAB AHI1 CTD-3074O7.12 U91328.21 ZNF76
Osteoporosis (self-reported) 1.2 1 0 0.0 0.00 1.0e+00 MRGPRF
Smoking status: Current 1.3 2 1 2.2 0.00 1.0e+00 LIME1 PRPS1P2
Forced expiratory volume in 1-second (FEV1), predicted percentage 4.2 40 25 55.6 0.90 6.1e-16 AC073834.3 ARL17B BCKDK BCL7C BOK C10orf11 CDC123 CEP120 CLEC18A CLUAP1 CTA-85E5.10 DHDDS EML3 GPR126 HSD3B7 INTS12 JAG1 KANSL1 LIME1 LRRC37A LRRC37A2 MGC57346 NDST2 NOB1 PPA2 PSMA4 QSOX2 RIN3 RNF123 RP11-538P18.2 RP11-967K21.1 RPL10A STX1B STX4 TEAD3 TRIM63 U91328.21 VKORC1 WHAMM WNT4
Whole body water mass 6.5 116 95 211.1 0.93 2.4e-59 ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CXCR2 CYB561 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MTMR3 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SNAI3-AS1 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF213 ZNF500 ZNF76
Leg predicted mass (right) 5.3 102 74 164.4 0.92 1.1e-50 ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DDX42 DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MTMR3 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-73O6.3 RPL10A RPS20 SCMH1 SEPT2 SLC38A2 SMARCD2 SNAI3-AS1 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF500 ZNF76
Arm fat mass (left) 2.3 31 23 51.1 -0.07 6.9e-01 AAGAB ADCY3 AP3B1 BCKDK C1QTNF4 CCDC171 CCDC87 CDK6 CEP120 CLEC18A FEZ2 FOXP1 GDF5 GNA12 HSD3B7 LIME1 NOB1 NUDT3 OTUD4 PACSIN1 PDXDC2 PIAS4 PTRHD1 RP11-179B2.2 RP11-443B20.1 RP11-73O6.3 RPL10A TBX6 TP53INP2 VKORC1 ZBTB38
Number of self-reported non-cancer illnesses 1.7 3 1 2.2 0.00 1.0e+00 AAGAB CCDC87 CTA-85E5.10
Average weekly champagne plus white wine intake 1.4 3 0 0.0 0.97 3.4e-02 KANSL1 LRRC37A LRRC37A2
Miserableness 1.3 5 2 4.4 -0.98 6.0e-04 HORMAD2 KANSL1 LOXL1-AS1 LRRC37A LRRC37A2
Guilty feelings 1.4 3 0 0.0 0.00 1.0e+00 LRRC37A LRRC37A2 UBXN2A
Medication: Blood pressure 1.4 5 1 2.2 0.51 3.0e-01 ADCY3 CHMP1A LRRC37A2 RP11-1055B8.4 ZNF500
Supplements: Fish oil (including cod liver oil) 1.3 2 0 0.0 0.00 1.0e+00 CCDC87 NFAT5
High cholesterol (Self-reported) 1.9 4 2 4.4 -0.99 5.1e-03 ABO FAM136A NOP58 VKORC1
Medication: Paracetamol 1.6 4 3 6.7 -0.66 2.3e-01 KANSL1 LRRC37A LRRC37A2 U91328.21
Medication: Atorvastatin 1.3 1 0 0.0 0.00 1.0e+00 ABO
Illnesses of father: High blood pressure 1.4 1 0 0.0 0.00 1.0e+00 NCOA1
Ever smoked 1.4 3 1 2.2 0.00 1.0e+00 NOA1 PRPS1P2 PSMA4
Basal metabolic rate 5.8 108 86 191.1 0.92 4.5e-54 ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CXCR2 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MFGE8 MPHOSPH6 MRGPRF MRPL42 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF500 ZNF76
Leg fat percentage (left) 3.0 43 26 57.8 -0.87 6.6e-17 AAGAB AC073834.3 ADCY3 ANKRD13B ARFGEF2 BCKDK C1QTNF4 CCDC171 CD79B CDK5RAP3 CENPW CLEC18A CTC-228N24.3 DARS DCAF16 DDX27 DDX42 DLG1 FOXP1 GDF5 GSK3A HABP4 HMBS HSD3B7 LIME1 NCAPG NOB1 NOV PIAS4 PIGF PLEKHM1P PTRHD1 RIN3 RP11-182J1.14 RP11-435O5.5 RP11-443B20.1 SAR1B SMARCD2 STX1B STX4 TEAD3 VKORC1 ZFAS1
Arm fat-free mass (left) 5.7 100 80 177.8 0.92 1.2e-50 ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C20orf199 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CXCR2 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MTMR3 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PLEKHA1 PLK1S1 PNKD PPA2 PTCH1 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 UBXN2A UIMC1 VKORC1 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF76
Number of operations (self-reported) 1.5 2 1 2.2 0.00 1.0e+00 MTMR3 PPA2
Average weekly beer plus cider intake 1.1 1 0 0.0 0.00 1.0e+00 RNF123
Irritability 1.6 8 5 11.1 -0.30 4.3e-01 ARL17B BCL7C HSD3B7 KANSL1 LRRC37A LRRC37A2 STX1B STX4
Ever had prostate specific antigen (PSA) test 1.4 1 0 0.0 0.00 1.0e+00 ZBTB38
Fractured/broken bones in last 5 years 1.5 3 0 0.0 0.00 1.0e+00 CRIPAK LRRC37A2 VKORC1
Diastolic blood pressure, automated reading 1.6 15 8 17.8 -0.42 8.6e-02 AAGAB ABO ACPL2 BCKDHB CEP120 DARS DCAF16 HSD3B7 JAG1 MYO9A NCAPG NOV RP11-538P18.2 SCMH1 U91328.21
Myopia 1.6 1 1 2.2 0.00 1.0e+00 QSOX2
Vascular/heart problems diagnosed by doctor 1.5 10 2 4.4 0.68 1.0e-02 ADCY3 BCKDK DCAF16 NCAPG NCOA1 NFAT5 PIAS4 RP11-538P18.2 TEAD3 VKORC1
Cholesterol lowering medication 1.8 3 0 0.0 0.00 1.0e+00 ABO ANKRD13B VKORC1
Pain experienced in last month 1.4 2 0 0.0 0.00 1.0e+00 CENPW PRPS1P2
Deep venous thrombosis (DVT) (self-reported) 1.5 2 2 4.4 0.00 1.0e+00 ABO CACFD1
Pack years of smoking 2.3 3 1 2.2 0.00 1.0e+00 CYB561 PIAS4 PSMA4
Impedance of whole body 2.2 50 38 84.4 0.08 5.6e-01 AC103965.1 ADCY3 AOC1 ATP13A2 BCKDK CD79B CDO1 CENPW CEP120 CRIPAK CROCC CTC-228N24.3 CTD-3076O17.1 CYBRD1 EDNRB EFEMP1 EML3 GDF5 GPR126 KANSL1 LOXL1-AS1 LRRC37A LRRC37A2 MAP3K1 MRGPRF MRPL42 MST1L MST1P2 MTERFD2 NUDT3 OTUD4 PACSIN1 PASK PLK1S1 PPA2 RAD9A RIN3 RP11-108M9.5 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 RPL10A RPS20 SCMH1 SLC38A2 TBX6 VKORC1
Leg fat mass (left) 2.2 30 22 48.9 -0.16 3.6e-01 AAGAB ADCY3 AP3B1 BCKDK C1QTNF4 CCDC171 CDK6 CLEC18A DARS DLG1 FOXP1 HSD3B7 LIME1 NOB1 NUDT3 OTUD4 PACSIN1 PIAS4 PTRHD1 RAD9A RP11-179B2.2 RP11-182J1.14 RP11-443B20.1 RP11-73O6.3 RPL10A SAR1B STX4 TBX6 VKORC1 ZBTB38
Arm predicted mass (left) 5.7 101 80 177.8 0.92 9.4e-51 ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C2orf52 CD79B CDK6 CENPW CEP120 CHMP1A CRIPAK CXCR2 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PLEKHA1 PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 UBXN2A UIMC1 VKORC1 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF76

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 65 1.9 4.1
GTEx Adipose Visceral Omentum 48 2.4 4.4
GTEx Adrenal Gland 29 2.0 3.9
GTEx Artery Aorta 62 2.1 4.3
GTEx Artery Coronary 32 2.7 4.6
GTEx Artery Tibial 75 2.0 4.1
GTEx Brain Caudate basal ganglia 15 1.6 3.8
GTEx Brain Cerebellar Hemisphere 34 2.3 4.3
GTEx Brain Cerebellum 43 2.2 4.3
GTEx Brain Cortex 28 2.7 4.4
GTEx Brain Frontal Cortex BA9 19 2.1 4.2
GTEx Brain Hippocampus 15 2.9 4.5
GTEx Brain Hypothalamus 19 3.2 4.5
GTEx Brain Nucleus accumbens basal ganglia 22 2.5 4.5
GTEx Brain Putamen basal ganglia 11 1.8 4.1
GTEx Breast Mammary Tissue 44 2.2 4.4
GTEx Breast Mammary Tissue (Male) 33 2.8 4.8
GTEx Breast Mammary Tissue (Female) 31 1.9 4.1
GTEx Cells EBV-transformed lymphocytes 40 2.8 4.7
GTEx Cells Transformed fibroblasts 81 1.9 3.9
GTEx Colon Sigmoid 29 2.0 4.3
GTEx Colon Transverse 47 2.3 4.2
GTEx Esophagus Gastroesophageal Junction 33 2.3 4.3
GTEx Esophagus Mucosa 69 2.1 4.1
GTEx Esophagus Muscularis 75 2.3 4.4
GTEx Heart Atrial Appendage 39 2.5 4.6
GTEx Heart Left Ventricle 31 2.0 4.1
GTEx Liver 18 2.5 4.3
GTEx Lung 72 2.5 4.2
GTEx Muscle Skeletal 46 1.6 3.9
GTEx Nerve Tibial 90 2.1 4.1
GTEx Ovary 27 3.0 5.2
GTEx Pancreas 34 2.1 4.2
GTEx Pituitary 37 3.3 4.8
GTEx Prostate 14 1.7 4.0
GTEx Skin Not Sun Exposed Suprapubic 53 2.2 4.2
GTEx Skin Sun Exposed Lower leg 73 2.0 4.2
GTEx Small Intestine Terminal Ileum 14 3.0 5.0
GTEx Spleen 27 1.9 4.4
GTEx Stomach 35 2.4 4.3
GTEx Testis 69 2.2 4.3
GTEx Thyroid 77 1.9 4.1
GTEx Uterus 19 3.4 5.1
GTEx Vagina 15 2.4 4.2
GTEx Whole Blood 40 2.0 3.9
METSIM Adipose 60 1.3 3.4
NTR Blood 39 1.6 3.5
ROSMAP Brain Pre-frontal Cortex 61 1.4 3.4
YFS Blood 61 1.3 3.3
CommonMind Brain Pre-frontal Cortex 68 1.3 3.3
The Cancer Genome Atlas Bladder Urothelial Carcinoma 27 1.6 3.5
The Cancer Genome Atlas Breast Invasive Carcinoma 66 1.5 3.5
The Cancer Genome Atlas Cervical Squamous Cell Carcinoma 18 1.6 3.7
The Cancer Genome Atlas Colon Adenocarcinoma 30 1.5 3.5
The Cancer Genome Atlas Esophageal Carcinoma 15 2.2 4.0
The Cancer Genome Atlas Glioblastoma Multiforme 24 2.3 4.0
The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma 47 1.7 3.6
The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma 65 1.6 3.5
The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma 27 1.3 3.4
The Cancer Genome Atlas Brain Lower Grade Glioma 74 1.7 3.5
The Cancer Genome Atlas Liver Hepatocellular Carcinoma 15 1.4 3.5
The Cancer Genome Atlas Lung Adenocarcinoma 47 1.6 3.5
The Cancer Genome Atlas Lung Squamous Cell Carcinoma 42 1.7 3.5
The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma 24 1.5 3.4
The Cancer Genome Atlas Pancreatic Adenocarcinoma 20 1.2 3.4
The Cancer Genome Atlas Pheochromocytoma and Paraganglioma 23 1.7 3.6
The Cancer Genome Atlas Prostate Adenocarcinoma 65 1.4 3.5
The Cancer Genome Atlas Rectum Adenocarcinoma 10 1.4 3.7
The Cancer Genome Atlas Soft Tissue Sarcoma 25 2.3 3.8
The Cancer Genome Atlas Skin Cutaneous Melanoma 10 1.9 3.7
The Cancer Genome Atlas Stomach Adenocarcinoma 23 1.4 3.4
The Cancer Genome Atlas Testicular Germ Cell Tumors 14 1.1 3.2
The Cancer Genome Atlas Thyroid Carcinoma 78 1.5 3.4
The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma 10 2.0 3.9