Hub : Traits :

Forced vital capacity (FVC)

2917 significantly associated models · 605 unique genes.

Significant Loci

#	chr	p0	p1	# assoc genes	# joint genes	best TWAS P	best SNP P	cond SNP P	% var exp	joint genes
1	1	16142960	18461490	16	8	3.1e-32	3.1e-32	1.0e+00	100	ATP13A2 CROCC ESPNP MST1L MST1P2 RP11-108M9.5
2	1	22197336	22718991	1	1	3.7e-14	1.5e-11	2.4e-04	70	WNT4
3	1	25475418	27971502	10	4	2.9e-13	1.6e-12	6.2e-01	100	DHDDS NUDC RPS6KA1 TRIM63
4	1	37764586	39186794	2	1	1.3e-07	1.1e-07	1.0e+00	100	FHL3
5	1	40748755	42542658	5	1	2.0e-29	3.1e-24	7.7e-01	100	SCMH1
6	1	67814420	69212053	1	1	4.0e-08	3.7e-08	5.2e-02	88	DIRAS3
7	1	87083322	87628173	1	1	2.7e-07	8.0e-07	5.4e-01	98	SEP15
8	2	23453834	25889403	8	11	9.9e-23	2.8e-21	NaN	NaN	ADCY3 NCOA1 PTRHD1 RP11-443B20.1 UBXN2A
9	2	35883253	37567226	5	1	1.8e-12	1.3e-11	5.1e-01	99	FEZ2
10	2	46117914	47538477	1	1	1.5e-08	5.2e-10	9.7e-03	83	PIGF
11	2	55079242	56843605	2	2	4.8e-53	3.1e-69	1.5e-09	88	EFEMP1
12	2	69678079	71228388	4	1	6.5e-12	6.9e-10	1.5e-03	74	FAM136A
13	2	100029106	101629737	2	1	3.2e-08	2.7e-08	1.1e-03	66	AC092667.2
14	2	134794256	137435625	7	1	3.7e-12	2.4e-11	1.5e-04	68	DARS
15	2	171478402	173114238	2	1	5.4e-12	2.8e-08	1.2e-02	80	CYBRD1
16	2	177559549	179672547	4	1	4.9e-12	1.2e-10	1.5e-01	95	AC073834.3
17	2	202434393	204433184	3	1	8.5e-08	3.6e-08	6.0e-03	75	NOP58
18	2	218300530	220374137	11	2	1.4e-14	7.0e-10	1.2e-08	14	CXCR2 PNKD
19	2	231628878	233349588	4	2	2.6e-10	1.7e-09	3.5e-02	88	C2orf52 RP11-690I21.1
20	2	241332207	243048760	6	6	3.1e-23	9.4e-19	NaN	NaN	BOK C2orf54 MTERFD2 PASK SEPT2
21	3	8294862	8858201	1	1	3.4e-09	3.7e-10	7.2e-04	71	LMCD1
22	3	32497274	33950934	1	1	1.2e-10	3.9e-11	1.2e-09	15	SUSD5
23	3	48702606	50448632	2	1	7.5e-08	5.8e-07	5.5e-04	52	RNF123
24	3	52166147	53560321	1	1	1.4e-07	2.0e-06	1.0e+00	100	RP5-966M1.6
25	3	70757099	71880670	1	1	1.9e-10	8.7e-13	2.5e-05	65	FOXP1
26	3	128276332	129714372	2	1	3.4e-14	4.0e-14	5.0e-04	79	H1FX
27	3	140250247	141867638	2	3	6.2e-24	1.5e-24	1.0e+00	100	ACPL2 ZBTB38
28	3	157125828	159106064	5	1	4.6e-22	4.5e-19	4.3e-03	90	RP11-538P18.2
29	3	171513388	172924003	2	2	7.5e-09	3.7e-14	5.9e-05	72	FNDC3B TNFSF10
30	3	196072442	197724684	1	2	3.4e-09	3.0e-10	1.6e-01	95	DLG1
31	4	673778	2058475	2	1	3.4e-09	1.7e-06	4.3e-01	97	CRIPAK
32	4	2233366	4219590	4	6	3.0e-09	2.9e-11	NaN	NaN	DOK7 LRPAP1 MFSD10
33	4	17104059	18507692	2	7	4.9e-46	5.4e-41	NaN	NaN	DCAF16 NCAPG
34	4	57080198	58531645	4	1	2.2e-10	3.4e-10	1.9e-01	96	NOA1
35	4	76660500	78402379	1	1	8.9e-09	3.2e-12	5.3e-05	66	SHROOM3
36	4	100238413	100791805	1	1	4.8e-09	1.8e-07	9.3e-01	100	MTTP
37	4	105373669	107622327	5	2	7.4e-17	2.3e-19	3.7e-02	95	INTS12 PPA2
38	4	144882744	146788825	3	2	1.5e-31	2.6e-30	9.1e-01	100	ANAPC10 OTUD4
39	5	55862596	56435767	1	1	3.6e-08	9.9e-09	1.3e-05	42	MAP3K1
40	5	64196669	65022213	1	1	1.2e-08	1.8e-10	4.4e-03	80	ADAMTS6
41	5	77052232	78753539	2	1	5.4e-20	7.9e-23	1.1e-04	85	AP3B1
42	5	107390303	109224099	1	1	3.7e-11	7.2e-13	2.4e-05	65	FER
43	5	114443019	115851911	1	1	1.2e-08	2.8e-09	5.1e-02	89	CDO1
44	5	121480516	123002130	2	2	7.6e-10	4.5e-13	1.0e-03	79	CEP120 CTB-36H16.2
45	5	126587995	128220643	4	1	8.0e-10	3.3e-09	3.3e-03	75	CTC-228N24.3
46	5	133164490	134935530	4	5	1.4e-12	1.6e-09	7.0e-07	32	CAMLG SAR1B
47	5	139348915	141214127	8	1	9.5e-09	2.8e-07	8.3e-01	100	ZMAT2
48	5	147825590	149338157	1	1	6.4e-08	9.9e-08	1.0e+00	100	ABLIM3
49	5	175662866	177260129	4	2	3.6e-13	1.0e-12	3.2e-02	91	RAB24 UIMC1
50	6	25285943	26689223	1	1	1.7e-13	3.4e-13	1.2e-05	64	U91328.21
51	6	33662667	36158878	13	10	9.3e-22	3.4e-32	NaN	NaN	NUDT3 PACSIN1 RPL10A TCP11 TEAD3 ZNF76
52	6	75319716	77324522	3	1	1.7e-10	1.3e-08	2.4e-01	96	FILIP1
53	6	80120201	81763771	2	1	1.6e-11	1.2e-11	2.5e-03	80	BCKDHB
54	6	108994161	110844259	9	1	3.8e-14	3.4e-14	1.0e+00	100	RP11-425D10.10
55	6	115880851	117481404	3	1	3.5e-09	7.5e-10	1.0e-02	83	FAM26F
56	6	125970401	127355237	1	1	8.9e-31	4.6e-33	5.2e-04	92	CENPW
57	6	129638583	132080991	4	2	6.3e-26	4.5e-27	7.3e-15	48	LOC285733 RP11-73O6.3
58	6	134905567	136516257	3	1	8.9e-09	2.7e-09	4.1e-03	77	AHI1
59	6	141924760	143855272	3	3	8.9e-30	1.5e-31	1.0e+00	100	GPR126 NMBR
60	6	158041511	159632250	1	1	3.3e-14	2.3e-11	4.8e-04	73	TULP4
61	7	2032803	3581391	2	1	1.0e-12	3.2e-12	2.3e-02	89	GNA12
62	7	22449883	24382726	4	3	3.9e-12	1.9e-21	9.7e-07	74	CCDC126 KLHL7 TRA2A
63	7	45255940	46658015	1	1	1.9e-08	3.8e-13	1.6e-11	14	IGFBP3
64	7	91380845	93160671	3	1	3.8e-13	3.8e-12	2.4e-01	97	CDK6
65	7	139700516	141316834	4	2	1.1e-10	9.4e-11	1.0e+00	100	BRAF NDUFB2
66	7	149847287	151252618	2	1	1.2e-09	7.8e-13	2.0e-05	65	AOC1
67	8	56269387	57683880	2	1	2.1e-13	5.7e-23	2.3e-11	54	RPS20
68	8	119737284	121136001	1	1	1.5e-10	2.2e-10	3.5e-09	14	NOV
69	8	123101743	124679448	1	1	6.8e-10	1.6e-10	6.3e-03	82	ZHX2
70	8	130517157	131045893	1	1	2.1e-20	5.9e-18	8.4e-04	85	GSDMC
71	9	14857740	16758776	1	1	1.9e-13	9.4e-14	6.4e-02	94	CCDC171
72	9	96326127	100114913	11	8	5.0e-22	1.7e-28	1.1e-03	91	C9orf3 ERCC6L2 HABP4 PTCH1 RP11-435O5.4 RP11-435O5.5 ZNF169
73	9	100871717	102304304	1	1	2.7e-08	1.4e-08	3.0e-06	32	GALNT12
74	9	127218258	128610269	1	1	6.5e-08	5.9e-07	4.4e-02	84	PRPS1P2
75	9	135521303	137034272	3	3	2.1e-08	2.2e-11	8.9e-03	85	ABO CACFD1 SURF1
76	9	138403706	139836362	1	1	6.1e-22	8.0e-20	3.0e-01	99	QSOX2
77	10	11515875	12989666	2	1	2.3e-10	1.8e-10	1.3e-03	75	CDC123
78	10	28113533	29610861	2	1	7.4e-08	3.1e-10	9.9e-11	-6	WAC-AS1
79	10	30887952	31565621	1	1	1.6e-07	3.8e-08	1.8e-02	81	ZNF438
80	10	74317852	76266883	3	2	9.9e-08	9.5e-08	1.0e+00	100	DNAJC9-AS1 NDST2
81	10	76664253	80383574	3	2	4.3e-09	8.5e-11	4.2e-04	70	C10orf11 DLG5
82	10	80443273	81901722	1	1	2.6e-11	2.3e-07	1.1e-02	76	ZCCHC24
83	10	88156839	89647154	1	1	3.1e-07	6.3e-06	8.2e-01	100	FAM35A
84	10	101975269	103362569	2	1	7.1e-09	1.3e-08	1.0e+00	100	RP11-179B2.2
85	10	103527782	105275242	4	1	3.1e-10	2.3e-07	9.4e-01	100	TMEM180
86	10	123438113	124889817	2	2	2.3e-09	2.8e-24	1.6e-15	39	ARMS2 PLEKHA1
87	11	18170688	18673155	1	1	7.7e-08	5.0e-08	2.8e-02	84	LDHA
88	11	32365430	33799671	3	1	1.2e-10	1.2e-08	7.7e-02	90	TCP11L1
89	11	46064974	48783497	18	1	2.5e-12	3.9e-11	3.6e-01	98	C1QTNF4
90	11	61678576	63078986	3	1	1.3e-08	2.8e-08	1.7e-07	11	EML3
91	11	64663227	69549801	23	10	1.3e-38	2.5e-35	1.0e+00	100	CCDC87 CTD-3074O7.12 CTD-3074O7.5 KCNK7 MRGPRF RAD9A RPS6KB2 SF3B2 TPCN2
92	11	76827992	78216992	2	1	1.8e-08	5.0e-06	3.0e-01	95	AP000580.1
93	11	116022447	117662909	1	1	1.9e-08	1.9e-10	4.9e-06	48	SIK3
94	11	118268613	119659753	1	1	6.8e-09	2.2e-08	5.0e-06	33	HMBS
95	12	403545	2299048	1	1	2.3e-08	5.1e-11	1.3e-06	46	ERC1
96	12	14713793	15223230	1	1	2.6e-07	2.2e-06	2.6e-01	94	C12orf60
97	12	20151739	21604108	1	1	7.5e-08	2.4e-09	9.9e-06	45	SLCO1C1
98	12	27616589	29042392	1	1	9.1e-14	4.1e-11	3.7e-01	98	RP11-967K21.1
99	12	30084002	31526510	1	1	1.2e-13	4.9e-14	1.0e+00	100	IPO8
100	12	46077695	47465082	1	1	4.5e-08	3.9e-10	2.4e-03	76	SLC38A2
101	12	55633142	57452308	11	1	7.3e-09	3.9e-08	8.7e-01	100	RP11-977G19.11
102	12	64519806	66337026	2	1	1.4e-11	3.4e-20	7.4e-24	-20	LEMD3
103	12	93165619	94589220	1	1	8.7e-11	2.9e-24	7.8e-16	37	MRPL42
104	12	101575652	103101412	3	2	2.8e-08	2.7e-10	8.0e-02	92	C12orf48 DRAM1
105	13	49375072	51390447	4	7	3.9e-18	4.2e-18	1.0e+00	100	DLEU2 EBPL
106	13	77787826	79188028	1	1	8.6e-08	1.5e-07	7.9e-02	89	EDNRB
107	14	36900126	37890433	1	1	3.7e-09	8.9e-10	3.3e-03	77	SLC25A21
108	14	72734342	74120838	1	1	2.5e-07	1.1e-07	8.1e-03	75	RP11-109N23.6
109	14	92286262	93847625	1	1	3.6e-16	3.8e-17	1.0e+00	100	RIN3
110	14	102288663	103675360	1	1	2.6e-08	7.6e-07	6.8e-01	99	ANKRD9
111	15	39530508	41012695	1	1	1.1e-09	4.4e-08	2.7e-06	27	EIF2AK4
112	15	50649361	52091785	1	1	7.7e-08	1.5e-09	3.2e-03	76	TNFAIP8L3
113	15	66797492	68492262	2	1	4.6e-09	1.3e-10	7.1e-04	72	AAGAB
114	15	71418503	73087366	2	1	4.1e-11	2.2e-09	8.6e-01	100	MYO9A
115	15	73524629	78022087	13	5	7.5e-21	6.9e-27	9.2e-19	32	CLK3 LOXL1-AS1 MAN2C1 RCN2
116	15	78135979	79537269	1	1	2.4e-07	3.9e-08	6.0e-02	88	PSMA4
117	15	83167559	85883064	11	3	1.5e-12	8.5e-20	4.0e-05	80	AC103965.1 RP11-182J1.14 WHAMM
118	15	89171135	89701439	2	2	1.2e-08	3.9e-14	1.2e-08	43	HAPLN3 MFGE8
119	15	99816860	101209341	1	1	3.0e-08	4.4e-14	1.3e-11	20	CTD-3076O17.1
120	16	86671	1488646	3	1	3.6e-08	5.8e-08	1.0e+00	100	NARFL
121	16	2510603	5510848	12	3	1.2e-15	3.9e-14	3.9e-03	85	CLUAP1 ZNF213 ZNF500
122	16	13697975	14759768	1	1	2.6e-08	9.0e-09	1.2e-03	68	RP11-65J21.3
123	16	29580611	31833122	14	9	3.7e-14	2.3e-12	1.0e+00	100	BCKDK BCL7C HSD3B7 MIR4519 RNF40 STX1B STX4 TBX6 VKORC1
124	16	68523336	71093625	14	9	4.7e-16	2.2e-25	NaN	NaN	CLEC18A COG4 NFAT5 NOB1 PDXDC2 TMED6
125	16	71848959	72342280	1	1	9.0e-08	2.2e-07	5.3e-02	86	HP
126	16	80779331	82901701	2	2	1.7e-08	1.2e-07	4.2e-01	98	CMIP MPHOSPH6
127	16	88030355	90172696	6	2	2.8e-10	1.9e-08	2.1e-05	43	CHMP1A SNAI3-AS1
128	17	970413	2420934	2	1	8.3e-08	5.6e-07	7.8e-01	100	SERPINF1
129	17	27200734	28952286	7	1	5.0e-10	2.7e-09	2.3e-01	96	ANKRD13B
130	17	36244358	37644854	1	1	1.7e-08	1.6e-07	1.3e-05	30	PIP4K2B
131	17	41946180	47688526	40	11	8.6e-42	5.6e-33	NaN	NaN	ARL17B ATP5G1 CDK5RAP3 KANSL1 LOC644172 LRRC37A LRRC37A2 LRRC37A4 MGC57346 PLCD3
132	17	60821100	64251733	20	9	9.3e-31	3.9e-28	NaN	NaN	AXIN2 CCDC47 CD79B CYB561 DDX42 PLEKHM1P SMARCD2
133	17	78665405	80866427	11	2	1.3e-16	1.8e-12	9.8e-05	69	DCXR RP11-1055B8.4
134	18	69836	907710	1	1	2.7e-07	3.0e-06	5.4e-03	64	USP14
135	18	59159599	60668346	1	1	2.1e-09	1.5e-05	7.7e-01	100	KIAA1468
136	19	3309021	4732167	1	1	1.1e-07	1.0e-09	6.3e-04	69	PIAS4
137	19	8367158	8848856	1	1	3.4e-09	6.5e-13	2.2e-08	39	MYO1F
138	19	10068513	11459260	2	1	5.8e-09	2.1e-08	7.4e-02	90	ILF3-AS1
139	19	40403029	43237764	6	2	1.9e-11	2.1e-11	1.0e+00	100	GSK3A SHKBP1
140	19	45496303	46981943	3	3	5.5e-09	4.3e-09	7.6e-02	91	DMPK RSPH6A SNRPD2
141	20	9925555	11347455	1	1	2.3e-09	5.2e-09	5.7e-03	78	JAG1
142	20	20857022	21474355	1	1	1.8e-07	6.9e-07	1.6e-01	92	PLK1S1
143	20	31382860	34697305	9	3	1.6e-11	5.4e-11	4.3e-01	98	E2F1 GDF5 TP53INP2
144	20	44824099	46516716	1	1	1.1e-07	8.4e-16	1.4e-09	43	EYA2
145	20	46551079	48603940	9	7	6.3e-22	7.2e-24	1.0e+00	100	ARFGEF2 C20orf199 CSE1L DDX27 ZFAS1
146	20	61522825	62912463	12	1	3.4e-16	4.3e-16	1.0e+00	100	LIME1
147	22	29707908	31171274	3	4	4.1e-13	3.0e-13	8.5e-01	100	CTA-85E5.10 HORMAD2 MTMR3

Pleiotropic Associations

Trait	chisq ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	corr	corr P	genes
Bipolar Disorder (2018)	1.1	1	0	0.0	0.00	1.0e+00	AC103965.1
Bipolar Disorder or Schizophrenia	1.1	9	4	8.9	-0.18	6.5e-01	AC103965.1 BRAF CTD-3074O7.12 CTD-3074O7.5 PACSIN1 PSMA4 RP5-966M1.6 U91328.21 ZMAT2
Depressed Affect (Nagel 2018)	1.7	7	4	8.9	-0.69	5.6e-02	ARL17B BCL7C HORMAD2 KANSL1 LRRC37A LRRC37A2 STX1B
Intelligence (Savage-Jansen 2018)	1.8	18	12	26.7	0.82	1.4e-06	ARFGEF2 C1QTNF4 CENPW CSE1L DCAF16 DDX27 FOXP1 HABP4 LRRC37A2 NCAPG PPA2 RNF123 RP11-435O5.5 RP5-966M1.6 TULP4 UBXN2A ZFAS1 ZMAT2
Neuroticism (Nagel 2018)	1.9	13	10	22.2	-0.29	2.9e-01	ARL17B BCKDK BCL7C CENPW HORMAD2 HSD3B7 KANSL1 LRRC37A LRRC37A2 MGC57346 PTCH1 STX1B STX4
Schizophrenia (2018)	1.1	4	2	4.4	0.67	3.3e-01	AC103965.1 PSMA4 U91328.21 ZMAT2
Schizophrenia vs Biploar Disorder	1.1	1	1	2.2	0.00	1.0e+00	CSE1L
Worry (Nagel 2018)	1.7	12	3	6.7	-0.02	9.5e-01	BCKDK BCL7C CENPW CTA-85E5.10 HORMAD2 HSD3B7 LRRC37A LRRC37A2 MTMR3 PTCH1 RP5-966M1.6 STX1B
Alzheimer’s Disease (including proxy)	1.3	2	1	2.2	0.00	1.0e+00	BCKDK RSPH6A
Crohns Disease (2017)	1.4	7	6	13.3	-0.45	1.9e-01	ADCY3 HORMAD2 LIME1 MTMR3 NDST2 RP11-443B20.1 ZBTB38
Irritable Bowel Disease (IBD)	1.6	9	4	8.9	-0.75	4.8e-03	ADCY3 CXCR2 DOK7 HORMAD2 LIME1 MTMR3 NCOA1 PTRHD1 RP11-443B20.1
Ulcerative Colitis (UC)	1.5	3	1	2.2	0.00	1.0e+00	DOK7 LIME1 RNF123
Major Depression (MDD)	1.2	1	0	0.0	0.00	1.0e+00	PTCH1
Reaction Time	1.3	4	0	0.0	0.12	8.8e-01	ADCY3 CSE1L PIAS4 TMEM180
Verbal and Numeric Reasoning (VNR)	2.0	17	10	22.2	0.71	7.0e-04	ADCY3 ARFGEF2 C1QTNF4 CENPW CSE1L DCAF16 DDX27 FOXP1 HABP4 NCAPG PPA2 RNF123 TULP4 U91328.21 UBXN2A ZFAS1 ZMAT2
Breast Cancer	1.8	8	8	17.8	-0.41	1.9e-01	ADCY3 LRRC37A LRRC37A2 MAP3K1 RIN3 RP11-443B20.1 RP11-73O6.3 ZBTB38
Ovarian Cancer	1.7	4	3	6.7	0.95	1.5e-02	KANSL1 LOC644172 LRRC37A LRRC37A2
Prostate Cancer	1.1	2	0	0.0	0.00	1.0e+00	LIME1 TMEM180
Bipolar Disorder (2011)	1.8	1	0	0.0	0.00	1.0e+00	RP5-966M1.6
Body Mass Index (BMI) (2010)	1.6	3	1	2.2	-0.99	1.1e-03	ADCY3 C1QTNF4 RP11-443B20.1
Coronary Artery Disease (CAD)	1.4	1	0	0.0	0.00	1.0e+00	DCAF16
Crohns Disease (2012)	1.4	4	1	2.2	-0.46	4.3e-01	ADCY3 HORMAD2 LIME1 MTMR3
HbA1C	1.1	1	0	0.0	0.00	1.0e+00	ABO
HDL Cholesterol	1.3	3	3	6.7	0.00	1.0e+00	C1QTNF4 MYO1F SIK3
LDL Cholesterol	1.5	2	2	4.4	0.00	1.0e+00	ABO CACFD1
Neuroticism (2016)	1.3	2	0	0.0	0.00	1.0e+00	LRRC37A LRRC37A2
Primary Biliary Cirrhosis	1.3	1	0	0.0	0.00	1.0e+00	LRRC37A2
Schizophrenia (2014)	1.1	1	1	2.2	0.00	1.0e+00	AC103965.1
Triglycerides	1.2	1	0	0.0	0.00	1.0e+00	BCKDK
Ulcerative Colitis	1.5	1	1	2.2	0.00	1.0e+00	LIME1
Blood Eosinophil Count	1.5	42	29	64.4	-0.29	3.5e-02	AAGAB ABO ADCY3 AHI1 ARL17B ATP5G1 CACFD1 CDK6 CTC-228N24.3 DLEU2 EBPL FAM136A FAM26F GNA12 GSK3A KANSL1 LRRC37A LRRC37A2 MGC57346 MRGPRF MYO1F NARFL NOA1 NOB1 NUDT3 PACSIN1 PDXDC2 RIN3 RNF40 RP11-109N23.6 RP11-425D10.10 RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 RPL10A SEPT2 TBX6 TCP11 TEAD3 TRIM63 WAC-AS1 ZNF169
Blood Platelet Count	1.2	53	43	95.6	-0.73	5.1e-11	ABO ANKRD13B ANKRD9 AP000580.1 ARL17B C1QTNF4 CACFD1 CDK6 CEP120 CTA-85E5.10 CXCR2 DCAF16 DDX42 DMPK E2F1 EDNRB FAM136A FER GNA12 HABP4 KANSL1 LIME1 LMCD1 LOC644172 LRRC37A LRRC37A4 MAN2C1 MGC57346 MIR4519 NARFL NCAPG NOA1 NUDT3 OTUD4 PACSIN1 PNKD RIN3 RNF40 RP11-109N23.6 RP11-425D10.10 RP5-966M1.6 SCMH1 SIK3 SMARCD2 SURF1 TBX6 TCP11 TEAD3 TMEM180 TULP4 ZCCHC24 ZHX2 ZNF500
Blood Red Count	2.6	63	45	100.0	-0.06	6.0e-01	ABO AC103965.1 ANKRD13B AOC1 ARL17B ATP13A2 BCKDK BCL7C C20orf199 CACFD1 CCDC87 CD79B CDK5RAP3 CENPW CLEC18A CSE1L CTD-3074O7.12 CTD-3074O7.5 CXCR2 DARS DDX27 DDX42 EIF2AK4 FAM136A GPR126 HSD3B7 KANSL1 KCNK7 LIME1 LOC644172 LRRC37A LRRC37A2 LRRC37A4 MAN2C1 MGC57346 MIR4519 MST1L MST1P2 MYO9A NCOA1 NFAT5 NOB1 NOV PIAS4 RAB24 RAD9A RCN2 RP11-109N23.6 RP11-435O5.5 RP11-73O6.3 RP11-977G19.11 RP5-966M1.6 RPS6KA1 SEPT2 SHKBP1 SLC25A21 SNAI3-AS1 STX1B STX4 SURF1 TBX6 VKORC1 ZBTB38
Blood White Count	1.6	59	36	80.0	-0.59	7.1e-08	ABO ADCY3 AHI1 ANKRD13B ARL17B C1QTNF4 CACFD1 CCDC126 CCDC47 CDK5RAP3 CDK6 CENPW CEP120 CLEC18A CTB-36H16.2 CXCR2 CYB561 DCAF16 DDX42 DLG5 EBPL EDNRB FER FNDC3B GNA12 GSK3A HABP4 HORMAD2 HSD3B7 KANSL1 LIME1 LOC644172 LRRC37A LRRC37A4 MAN2C1 NOA1 NOB1 PACSIN1 PDXDC2 PNKD PTRHD1 RCN2 RIN3 RP11-435O5.5 RP11-443B20.1 RP11-73O6.3 RPL10A SCMH1 SIK3 SMARCD2 TMEM180 TPCN2 TRA2A TULP4 UBXN2A WAC-AS1 ZHX2 ZNF169 ZNF76
Heel T-Score	2.8	74	57	126.7	-0.36	5.3e-04	AAGAB ABO ADAMTS6 ADCY3 ANAPC10 ANKRD13B AP000580.1 ARL17B ARMS2 AXIN2 BCKDK C12orf48 CACFD1 CDK5RAP3 CDK6 CEP120 CHMP1A CRIPAK CTA-85E5.10 CTB-36H16.2 CYBRD1 DCAF16 DCXR DDX42 DIRAS3 DLEU2 DLG1 E2F1 EBPL EML3 EYA2 FHL3 GNA12 GPR126 GSDMC H1FX HSD3B7 IPO8 JAG1 KANSL1 LIME1 LOC644172 LRRC37A LRRC37A2 MRGPRF NCAPG NCOA1 NDST2 NOA1 NOV PIP4K2B PLCD3 PLEKHM1P RP11-435O5.4 RP11-435O5.5 RP11-73O6.3 RP11-967K21.1 RP5-966M1.6 RPL10A RPS20 SCMH1 SMARCD2 SNAI3-AS1 TBX6 TNFAIP8L3 TPCN2 TULP4 WHAMM WNT4 ZBTB38 ZCCHC24 ZNF169 ZNF438 ZNF76
BMI	2.6	55	34	75.6	-0.61	6.2e-08	AAGAB AC092667.2 ADCY3 ANKRD13B AP3B1 ARFGEF2 ATP13A2 BCKDK C1QTNF4 CCDC171 CCDC47 CDK5RAP3 CEP120 CLEC18A CMIP CXCR2 DCAF16 DDX27 DDX42 DLG1 EDNRB EIF2AK4 FOXP1 GSK3A HABP4 HSD3B7 LOXL1-AS1 MFSD10 MST1L MST1P2 MYO9A NFAT5 NOB1 NOP58 NUDC NUDT3 OTUD4 PACSIN1 PDXDC2 PIAS4 PIGF PTRHD1 RNF123 RP11-179B2.2 RP11-443B20.1 RP11-538P18.2 RP11-73O6.3 RP5-966M1.6 RPL10A SAR1B SMARCD2 TBX6 TMED6 VKORC1 ZFAS1
Height	10.9	218	206	457.8	0.92	9.9e-105	AAGAB ABO AC103965.1 ACPL2 ADAMTS6 ADCY3 AHI1 ANAPC10 ANKRD13B ANKRD9 AOC1 AP000580.1 AP3B1 ARFGEF2 ARMS2 ATP13A2 ATP5G1 AXIN2 BCKDHB BOK BRAF C10orf11 C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 C2orf54 C9orf3 CACFD1 CAMLG CCDC126 CCDC47 CCDC87 CD79B CDC123 CDK6 CDO1 CENPW CEP120 CHMP1A CLEC18A CLK3 CLUAP1 CMIP COG4 CRIPAK CROCC CSE1L CTA-85E5.10 CTC-228N24.3 CTD-3074O7.12 CTD-3074O7.5 CTD-3076O17.1 CXCR2 CYB561 CYBRD1 DCAF16 DCXR DDX27 DDX42 DHDDS DIRAS3 DLEU2 DLG5 DNAJC9-AS1 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 ERC1 ERCC6L2 ESPNP FAM136A FAM26F FER FEZ2 FHL3 FILIP1 FNDC3B GDF5 GNA12 GPR126 GSDMC GSK3A H1FX HABP4 HAPLN3 HORMAD2 HP IGFBP3 ILF3-AS1 IPO8 JAG1 KANSL1 KCNK7 KLHL7 LDHA LEMD3 LIME1 LMCD1 LOC285733 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 MAP3K1 MFGE8 MFSD10 MGC57346 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTERFD2 MTMR3 MTTP MYO1F MYO9A NARFL NCAPG NCOA1 NDUFB2 NFAT5 NMBR NOA1 NOB1 NOP58 NOV NUDC NUDT3 OTUD4 PACSIN1 PASK PDXDC2 PIAS4 PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 PTRHD1 QSOX2 RAB24 RAD9A RCN2 RNF40 RP11-1055B8.4 RP11-108M9.5 RP11-109N23.6 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-538P18.2 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RP11-977G19.11 RP5-966M1.6 RPL10A RPS20 RPS6KA1 RPS6KB2 SAR1B SCMH1 SEP15 SEPT2 SERPINF1 SF3B2 SHKBP1 SIK3 SLC25A21 SLC38A2 SLCO1C1 SMARCD2 SNAI3-AS1 SNRPD2 SURF1 SUSD5 TBX6 TCP11 TEAD3 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 USP14 WAC-AS1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF169 ZNF213 ZNF500 ZNF76
Waist Hip Ratio (WHR)	2.3	45	24	53.3	-0.20	1.7e-01	AAGAB AC103965.1 ADCY3 ANAPC10 AP3B1 ARL17B ATP13A2 BCKDHB C12orf48 CD79B CENPW CLUAP1 CROCC DCXR EBPL EML3 EYA2 GDF5 KANSL1 LOC644172 LRRC37A LRRC37A2 LRRC37A4 MGC57346 MST1L MST1P2 MYO1F NCOA1 NFAT5 OTUD4 PIP4K2B PLK1S1 PRPS1P2 RAB24 RAD9A RP11-108M9.5 RP11-182J1.14 RP11-73O6.3 SF3B2 SNRPD2 TNFAIP8L3 TPCN2 UIMC1 WNT4 ZBTB38
Systolic Blood Pressure	1.7	32	24	53.3	-0.38	1.1e-02	ACPL2 ADCY3 ARFGEF2 ATP5G1 C12orf48 CDC123 CDK6 CEP120 CYBRD1 DCAF16 DOK7 EFEMP1 FER FHL3 GDF5 LOC285733 LRRC37A2 NCAPG NCOA1 NOV PLEKHM1P PTRHD1 RIN3 RP11-1055B8.4 RP11-179B2.2 RP11-443B20.1 RP11-538P18.2 RPL10A TEAD3 ZFAS1 ZMAT2 ZNF500
Smoking Status	1.4	7	3	6.7	-0.45	2.6e-01	FOXP1 LRRC37A2 NOB1 PDXDC2 PRPS1P2 RP5-966M1.6 TMEM180
Allergy or Eczema	1.3	7	4	8.9	-0.12	7.8e-01	AAGAB AHI1 CXCR2 LIME1 PACSIN1 TMEM180 ZBTB38
Cardiovascular Disease	1.6	16	6	13.3	-0.71	6.7e-04	AAGAB ADCY3 ATP5G1 BCKDK CDK6 DCAF16 DDX42 HSD3B7 MFSD10 NCAPG NCOA1 NOP58 RP11-1055B8.4 RP11-538P18.2 SMARCD2 VKORC1
Hypothyroidism (self reported)	1.3	7	5	11.1	-0.22	6.4e-01	AHI1 ARMS2 HORMAD2 MTMR3 PLEKHA1 SEPT2 SIK3
Respiratory disease	1.7	7	3	6.7	-0.67	6.7e-02	AAGAB AHI1 CTD-3074O7.12 LIME1 NOA1 ZNF169 ZNF76
Type 2 Diabetes (T2D) (2018)	1.5	5	1	2.2	-0.30	6.2e-01	CENPW CLEC18A DMPK MAN2C1 NOB1
Lung FEV1/FVC ratio	4.7	61	45	100.0	-0.44	9.3e-05	ABLIM3 AC103965.1 ADCY3 ANKRD13B ARMS2 ATP13A2 C10orf11 CCDC171 CDC123 CDK5RAP3 CENPW CEP120 CROCC CTA-85E5.10 CTC-228N24.3 DNAJC9-AS1 DRAM1 EFEMP1 EIF2AK4 ERC1 FEZ2 GDF5 GNA12 GPR126 HSD3B7 INTS12 LMCD1 LOXL1-AS1 LRRC37A MST1L MST1P2 MTERFD2 MYO1F NCOA1 NDST2 NMBR NOA1 NOV OTUD4 PIP4K2B PLEKHA1 PLEKHM1P PPA2 PSMA4 PTCH1 PTRHD1 RCN2 RP11-108M9.5 RP11-182J1.14 RP11-435O5.5 RP11-443B20.1 RPL10A RPS20 SEPT2 SHKBP1 TCP11 TEAD3 WHAMM ZBTB38 ZFAS1 ZNF76
Lung FVC	6.2	145	112	248.9	0.89	6.8e-60	AAGAB ABLIM3 ABO AC073834.3 AC092667.2 AHI1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARL17B ARMS2 ATP13A2 BCKDK BCL7C BOK BRAF C10orf11 C12orf48 C2orf54 C9orf3 CACFD1 CCDC126 CCDC171 CCDC87 CD79B CDC123 CDK5RAP3 CENPW CEP120 CLEC18A CLUAP1 COG4 CROCC CTA-85E5.10 CTB-36H16.2 CTC-228N24.3 DARS DCAF16 DCXR DDX27 DHDDS DIRAS3 DLG1 DOK7 EBPL EFEMP1 EIF2AK4 EML3 ERC1 EYA2 FAM136A FAM26F FEZ2 FOXP1 GALNT12 GDF5 GSDMC GSK3A HMBS HORMAD2 HSD3B7 INTS12 IPO8 JAG1 KANSL1 KCNK7 LIME1 LMCD1 LOC285733 LOC644172 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 LRRC37A4 MAN2C1 MFSD10 MGC57346 MIR4519 MST1L MST1P2 NCAPG NCOA1 NDST2 NDUFB2 NFAT5 NOA1 NOB1 NOP58 NOV PDXDC2 PLCD3 PLEKHM1P PLK1S1 PPA2 PSMA4 PTCH1 QSOX2 RAD9A RIN3 RNF123 RP11-1055B8.4 RP11-108M9.5 RP11-425D10.10 RP11-435O5.5 RP11-538P18.2 RP11-73O6.3 RP11-967K21.1 RP11-977G19.11 RPL10A RPS20 RPS6KA1 RPS6KB2 SAR1B SCMH1 SEP15 SEPT2 SF3B2 SHKBP1 SHROOM3 SIK3 SLC25A21 SLC38A2 SNAI3-AS1 STX1B STX4 SURF1 SUSD5 TCP11 TCP11L1 TEAD3 TRIM63 TULP4 UBXN2A USP14 VKORC1 WHAMM WNT4 ZBTB38 ZFAS1 ZMAT2 ZNF213 ZNF438 ZNF500
Neuroticism	1.9	14	9	20.0	-0.39	1.3e-01	AAGAB ARL17B BCL7C CENPW HORMAD2 HSD3B7 KANSL1 LRRC37A LRRC37A2 MGC57346 PRPS1P2 PTCH1 STX1B STX4
Chronotype (morning person)	1.2	1	1	2.2	0.00	1.0e+00	CYB561
Hair Pigment	1.8	24	22	48.9	-0.12	5.5e-01	ADCY3 ARL17B BRAF CCDC87 CHMP1A DCXR E2F1 EDNRB FAM136A GDF5 HMBS KANSL1 LRRC37A MRGPRF NOA1 RP11-73O6.3 RPS6KB2 SLC38A2 SNAI3-AS1 TP53INP2 TPCN2 TULP4 ZBTB38 ZNF76
Tanning	1.3	8	7	15.6	0.58	8.0e-02	ADCY3 CHMP1A E2F1 GDF5 RP11-443B20.1 RP5-966M1.6 SNAI3-AS1 TP53INP2
Hand grip strength (left)	4.6	46	26	57.8	0.97	3.3e-39	ADCY3 AOC1 AP000580.1 ARFGEF2 AXIN2 BRAF C12orf48 C1QTNF4 CCDC87 CD79B CHMP1A CLEC18A CTD-3074O7.12 CYB561 DARS DCAF16 DLG5 FER FOXP1 GDF5 H1FX JAG1 KANSL1 LOXL1-AS1 LRRC37A LRRC37A2 NCAPG NCOA1 NOB1 PDXDC2 PIGF PIP4K2B PRPS1P2 PTRHD1 RAD9A RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 SLC38A2 TBX6 TCP11 TMEM180 TRA2A ZBTB38 ZCCHC24 ZNF500
Number of treatments/medications taken	1.6	2	0	0.0	0.00	1.0e+00	DCAF16 NCAPG
Sensitivity / hurt feelings	1.9	6	5	11.1	-0.68	6.3e-02	ARL17B KANSL1 LRRC37A LRRC37A2 MGC57346 PTCH1
Frequency of depressed mood in last 2 weeks	1.4	2	0	0.0	0.00	1.0e+00	LRRC37A2 ZFAS1
Hearing difficulty/problems: Yes	1.5	1	1	2.2	0.00	1.0e+00	ABLIM3
Relative age of first facial hair	2.0	9	5	11.1	-0.48	1.3e-01	ARL17B CHMP1A KANSL1 LEMD3 LRRC37A LRRC37A2 RP11-179B2.2 RP11-65J21.3 ZBTB38
Systolic blood pressure, automated reading	1.8	15	5	11.1	-0.44	5.3e-02	ADCY3 ATP5G1 CDK6 DCAF16 DOK7 EFEMP1 FER FHL3 LRRC37A2 NCAPG NOV PPA2 RP11-1055B8.4 RP11-538P18.2 ZNF500
Diabetes (mother)	1.6	1	0	0.0	0.00	1.0e+00	SNRPD2
Pack years adult smoking proportion	2.2	3	1	2.2	0.00	1.0e+00	CYB561 PIAS4 PSMA4
Impedance of leg (right)	2.4	46	28	62.2	-0.05	7.2e-01	ABO AC103965.1 ADCY3 AOC1 AP3B1 ATP13A2 CD79B CDK6 CDO1 CEP120 CRIPAK CROCC CTC-228N24.3 CTD-3074O7.5 CTD-3076O17.1 CYBRD1 EDNRB GDF5 H1FX LOXL1-AS1 MAP3K1 MRGPRF MST1L MST1P2 MTERFD2 NDST2 NUDT3 OTUD4 PACSIN1 PASK PTCH1 RAD9A RIN3 RP11-108M9.5 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 RPS20 SLC38A2 SNAI3-AS1 TBX6 TCP11L1 WNT4
Leg fat-free mass (left)	5.2	98	73	162.2	0.92	2.4e-48	ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DDX42 DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LOXL1-AS1 MFGE8 MPHOSPH6 MRGPRF MRPL42 MYO1F NARFL NCAPG NMBR NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.5 RP11-73O6.3 RPL10A RPS20 SCMH1 SEPT2 SLC38A2 SMARCD2 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF500 ZNF76
Trunk fat percentage	2.5	35	27	60.0	-0.24	1.4e-01	AAGAB AC103965.1 ADCY3 AP3B1 ARFGEF2 BCKDK C1QTNF4 CCDC171 CENPW CLEC18A CTD-3076O17.1 DARS DLG1 EFEMP1 EML3 FEZ2 FOXP1 GNA12 HSD3B7 LIME1 LRRC37A2 NOB1 OTUD4 PACSIN1 PASK PIAS4 PTRHD1 RAD9A RIN3 RP11-182J1.14 RP11-443B20.1 STX1B TEAD3 VKORC1 ZBTB38
Hand grip strength (right)	4.7	43	26	57.8	0.96	1.2e-33	ACPL2 ADCY3 AOC1 AP000580.1 ARFGEF2 AXIN2 C12orf48 C1QTNF4 CD79B CLEC18A CRIPAK CYB561 CYBRD1 DARS DCAF16 DLG5 GDF5 H1FX HABP4 JAG1 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 NCAPG NCOA1 NOB1 PDXDC2 PIP4K2B PLCD3 PRPS1P2 PTRHD1 RAD9A RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 SCMH1 TBX6 TMEM180 TRA2A TULP4 ZBTB38 ZCCHC24
Townsend deprivation index at recruitment	1.2	2	0	0.0	0.00	1.0e+00	BCKDK GPR126
Current tobacco smoking	1.2	2	2	4.4	0.00	1.0e+00	LIME1 PRPS1P2
Fed-up feelings	1.4	4	3	6.7	-0.94	1.8e-02	HORMAD2 KANSL1 LRRC37A LRRC37A2
Relative age voice broke	1.8	6	4	8.9	-0.86	1.2e-02	ARL17B KANSL1 LRRC37A LRRC37A2 RP11-65J21.3 SCMH1
Taking other prescription medications	1.3	1	0	0.0	0.00	1.0e+00	AHI1
Age when periods started (menarche)	2.0	12	8	17.8	0.51	4.3e-02	ADCY3 C1QTNF4 CAMLG CENPW CLEC18A NFAT5 NOB1 PDXDC2 RP11-179B2.2 RP11-65J21.3 SAR1B SCMH1
Bilateral oophorectomy (both ovaries removed)	1.2	1	1	2.2	0.00	1.0e+00	WNT4
Heel bone mineral density (BMD) T-score, automated (left)	2.0	12	7	15.6	-0.48	5.8e-02	CDK6 CRIPAK DLEU2 EBPL FHL3 JAG1 MRGPRF RP11-435O5.5 TPCN2 WNT4 ZNF169 ZNF438
Qualifications: CSEs or equivalent	1.2	1	0	0.0	0.00	1.0e+00	KANSL1
High blood pressure	1.5	8	4	8.9	-0.32	3.4e-01	ADCY3 BCKDK DCAF16 LRRC37A2 NCAPG NCOA1 PIAS4 RP11-538P18.2
Hayfever, allergic rhinitis or eczema	1.1	4	3	6.7	-0.30	6.2e-01	AHI1 LIME1 TMEM180 ZBTB38
Medication: Levothyroxine sodium	1.1	2	1	2.2	0.00	1.0e+00	HORMAD2 SEPT2
Sitting height	9.6	174	150	333.3	0.93	1.2e-88	ABO AC073834.3 AC103965.1 ACPL2 ADCY3 ANAPC10 AOC1 AP3B1 ARFGEF2 ARL17B ATP13A2 ATP5G1 AXIN2 BCKDHB BOK C12orf60 C1QTNF4 C20orf199 C2orf52 C9orf3 CAMLG CCDC126 CCDC171 CCDC47 CD79B CDK6 CDO1 CENPW CEP120 CHMP1A CLEC18A CLK3 CMIP COG4 CRIPAK CROCC CSE1L CTD-3076O17.1 CXCR2 CYBRD1 DCAF16 DCXR DDX27 DDX42 DHDDS DLEU2 DLG5 DMPK DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 ERC1 ERCC6L2 ESPNP EYA2 FAM136A FAM26F FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC GSK3A H1FX HABP4 HAPLN3 HORMAD2 IGFBP3 ILF3-AS1 JAG1 KANSL1 KCNK7 KLHL7 LEMD3 LOC644172 LOXL1-AS1 LRRC37A LRRC37A2 LRRC37A4 MAN2C1 MAP3K1 MFGE8 MGC57346 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTERFD2 MTMR3 MTTP MYO1F MYO9A NARFL NCAPG NCOA1 NFAT5 NMBR NOB1 NOV NUDC NUDT3 OTUD4 PACSIN1 PASK PDXDC2 PIGF PIP4K2B PLCD3 PLEKHA1 PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 PTRHD1 QSOX2 RAB24 RAD9A RCN2 RP11-1055B8.4 RP11-108M9.5 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-538P18.2 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RP11-967K21.1 RP5-966M1.6 RPL10A RPS20 RPS6KA1 RSPH6A SAR1B SCMH1 SEPT2 SERPINF1 SLC25A21 SLC38A2 SMARCD2 SNAI3-AS1 SNRPD2 SURF1 TBX6 TEAD3 TMED6 TMEM180 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 TULP4 UBXN2A WAC-AS1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF169 ZNF76
Chronic bronchitis/emphysema (father)	1.5	1	1	2.2	0.00	1.0e+00	PSMA4
Body mass index (BMI)	2.5	34	19	42.2	-0.60	3.9e-05	AC092667.2 ADCY3 AP3B1 ARFGEF2 ATP13A2 BCKDK C1QTNF4 CCDC171 CCDC87 CDK5RAP3 CEP120 CLEC18A CXCR2 DCAF16 FOXP1 HSD3B7 NOB1 NUDC NUDT3 OTUD4 PACSIN1 PDXDC2 PIAS4 PIGF PTRHD1 RP11-179B2.2 RP11-443B20.1 RP5-966M1.6 RPL10A SAR1B TBX6 TMED6 VKORC1 ZFAS1
Impedance of leg (left)	2.4	49	28	62.2	0.07	5.9e-01	ABO AC103965.1 ADCY3 AOC1 AP3B1 ATP13A2 CD79B CDO1 CEP120 CHMP1A CROCC CTC-228N24.3 CTD-3074O7.12 CTD-3074O7.5 CTD-3076O17.1 CXCR2 CYBRD1 EDNRB GDF5 GPR126 H1FX KANSL1 LOXL1-AS1 LRRC37A2 MAP3K1 MRGPRF MST1L MST1P2 MTERFD2 NDST2 NUDT3 OTUD4 PACSIN1 PASK PPA2 PTCH1 RAD9A RIN3 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 RPS20 SEPT2 SLC38A2 TBX6 WNT4
Leg predicted mass (left)	5.2	98	73	162.2	0.92	6.1e-49	ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DDX42 DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LOXL1-AS1 MFGE8 MPHOSPH6 MRGPRF MRPL42 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.5 RP11-73O6.3 RPL10A RPS20 SCMH1 SEPT2 SLC38A2 SMARCD2 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF500 ZNF76
Trunk fat mass	2.6	43	33	73.3	0.35	1.4e-02	AAGAB AC103965.1 ADCY3 ANAPC10 AP3B1 BCKDK C1QTNF4 CCDC171 CDK6 CEP120 CLEC18A CTD-3076O17.1 DLG1 E2F1 EFEMP1 EIF2AK4 FEZ2 FOXP1 GDF5 GNA12 GPR126 H1FX HAPLN3 HSD3B7 LIME1 LRRC37A2 NOB1 OTUD4 PACSIN1 PIAS4 PLEKHA1 RAD9A RP11-179B2.2 RP11-182J1.14 RP11-443B20.1 RP11-73O6.3 RPL10A STX1B TBX6 TP53INP2 VKORC1 ZBTB38 ZNF500
Waist circumference	2.1	27	22	48.9	-0.11	5.6e-01	AAGAB AC092667.2 ADCY3 AP3B1 BCKDK C1QTNF4 CCDC171 CDK5RAP3 CDK6 CEP120 CLEC18A HSD3B7 LIME1 NOB1 NUDT3 OTUD4 PACSIN1 PIAS4 RAD9A RP11-179B2.2 RP11-443B20.1 RPL10A SAR1B STX1B TBX6 VKORC1 ZBTB38
Number of incorrect matches in round	1.7	3	2	4.4	0.00	1.0e+00	BCKDK TBX6 VKORC1
Past tobacco smoking	1.4	5	1	2.2	0.52	3.7e-01	NOA1 NOB1 PRPS1P2 RP11-977G19.11 TMEM180
Alcohol usually taken with meals	1.3	1	1	2.2	0.00	1.0e+00	FOXP1
Nervous feelings	1.5	6	1	2.2	-0.82	2.4e-02	CENPW CTA-85E5.10 LRRC37A LRRC37A2 RP5-966M1.6 TBX6
Frequency of tenseness / restlessness in last 2 weeks	1.4	4	2	4.4	-1.00	2.1e-04	ARL17B KANSL1 LRRC37A LRRC37A2
Hearing difficulty/problems with background noise	1.4	1	0	0.0	0.00	1.0e+00	LRRC37A2
Hair/balding pattern: Pattern 2	1.3	2	2	4.4	0.00	1.0e+00	C10orf11 LRRC37A2
Had other major operations	1.2	1	0	0.0	0.00	1.0e+00	PPA2
Heel bone mineral density (BMD) T-score, automated (right)	2.0	16	8	17.8	-0.56	1.7e-02	CDK6 CRIPAK DCAF16 DLEU2 EBPL FHL3 MRGPRF NCAPG NOA1 RP11-435O5.5 TPCN2 WNT4 ZBTB38 ZNF169 ZNF438 ZNF76
Ever unenthusiastic/disinterested for a whole week	1.4	2	0	0.0	0.00	1.0e+00	KANSL1 ZMAT2
Qualifications: None of the above	1.3	4	0	0.0	-0.98	2.1e-02	ATP5G1 FOXP1 PPA2 RNF123
Allergy	1.3	9	6	13.3	0.29	4.2e-01	AAGAB ABO AHI1 AP000580.1 CTD-3074O7.12 CTD-3074O7.5 LIME1 TMEM180 ZBTB38
Diabetes (self-reported)	1.6	2	0	0.0	0.00	1.0e+00	CLUAP1 MAN2C1
Medication: Simvastatin	1.6	2	1	2.2	0.00	1.0e+00	ABO DCAF16
Fluid intelligence score	1.8	8	2	4.4	0.89	2.9e-04	C1QTNF4 CSE1L DCAF16 FOXP1 NCAPG PPA2 RNF123 U91328.21
Illnesses of siblings	1.6	2	0	0.0	0.00	1.0e+00	BCKDK VKORC1
Neuroticism score	1.7	11	9	20.0	-0.29	3.4e-01	ARL17B BCL7C HORMAD2 HSD3B7 KANSL1 LRRC37A LRRC37A2 MGC57346 PTCH1 STX1B STX4
Weight	3.7	73	52	115.6	0.75	8.0e-17	AAGAB AC103965.1 ADCY3 ANAPC10 AP3B1 ARMS2 BCKDHB BCKDK BOK C12orf60 CCDC171 CD79B CDK6 CENPW CEP120 CRIPAK CTD-3076O17.1 CYBRD1 DCAF16 DDX42 DLEU2 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 GDF5 GNA12 GPR126 H1FX HAPLN3 HORMAD2 HSD3B7 ILF3-AS1 LIME1 MPHOSPH6 MRGPRF MRPL42 MYO1F NARFL NCAPG NMBR NUDT3 OTUD4 PACSIN1 PLEKHA1 PPA2 RAD9A RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-435O5.5 RP11-443B20.1 RP11-73O6.3 RPL10A RPS20 SCMH1 SEPT2 SERPINF1 SLC38A2 TBX6 TCP11 TEAD3 TMEM180 TP53INP2 TRA2A VKORC1 WNT4 ZBTB38 ZCCHC24 ZNF500 ZNF76
Impedance of arm (right)	2.1	41	29	64.4	0.16	2.8e-01	AAGAB AC103965.1 AOC1 ATP13A2 BCKDK CD79B CENPW CEP120 CRIPAK CTD-3076O17.1 CYBRD1 EFEMP1 EML3 FER FEZ2 GPR126 LOXL1-AS1 LRPAP1 LRRC37A2 MFGE8 MRPL42 MST1L MST1P2 MTERFD2 NUDT3 PACSIN1 PASK PLK1S1 RIN3 RP11-108M9.5 RP11-179B2.2 RP11-182J1.14 RP11-73O6.3 RP5-966M1.6 RPL10A RPS20 SAR1B SCMH1 SLC38A2 TBX6 VKORC1
Arm fat percentage (right)	3.0	37	24	53.3	-0.80	3.9e-11	AAGAB ABO ADCY3 ANKRD13B AP3B1 ARFGEF2 BCKDK C1QTNF4 CCDC171 CCDC87 CD79B CDK5RAP3 CENPW CLEC18A CTD-3074O7.12 CTD-3074O7.5 DCAF16 DDX27 DLG1 FOXP1 HABP4 HSD3B7 LIME1 NCAPG NOB1 NOP58 NOV PDXDC2 PIAS4 PIGF PTRHD1 RP11-443B20.1 SAR1B TBX6 TEAD3 VKORC1 ZFAS1
Trunk fat-free mass	7.3	128	98	217.8	0.93	7.9e-67	ACPL2 ADCY3 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP13A2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 C9orf3 CCDC47 CD79B CDK6 CENPW CEP120 CHMP1A CRIPAK CSE1L CXCR2 CYB561 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FAM136A FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MST1L MTMR3 MYO1F MYO9A NARFL NCAPG NCOA1 NDUFB2 NMBR NOA1 NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 PTRHD1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SAR1B SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SNAI3-AS1 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF213 ZNF500 ZNF76
Hip circumference	3.0	53	35	77.8	0.44	5.3e-04	AC103965.1 ADCY3 ANAPC10 AP3B1 BCKDK BCL7C BOK C1QTNF4 C2orf54 CCDC171 CD79B CDK6 CEP120 CLEC18A CYBRD1 DLEU2 E2F1 EFEMP1 EIF2AK4 EYA2 FEZ2 GDF5 GNA12 GPR126 H1FX HSD3B7 LIME1 NARFL NOB1 NUDT3 OTUD4 PACSIN1 PLEKHA1 RAD9A RP11-179B2.2 RP11-182J1.14 RP11-435O5.5 RP11-443B20.1 RP11-73O6.3 RPL10A RPS20 SCMH1 SEPT2 SLC38A2 STX1B STX4 TBX6 TEAD3 TP53INP2 TPCN2 VKORC1 WNT4 ZBTB38
Father's age at death	1.2	1	1	2.2	0.00	1.0e+00	PSMA4
Worrier / anxious feelings	1.6	6	3	6.7	-0.12	8.0e-01	HSD3B7 LRRC37A2 PTCH1 RP5-966M1.6 STX1B TMEM180
Frequency of tiredness / lethargy in last 2 weeks	1.4	3	0	0.0	0.00	1.0e+00	ATP5G1 DDX27 ZFAS1
Hair/balding pattern: Pattern 3	2.1	6	5	11.1	0.71	7.2e-02	ARL17B CENPW KANSL1 LOC644172 LRRC37A LRRC37A2
Number of live births	1.2	2	1	2.2	0.00	1.0e+00	LRRC37A WNT4
Forced expiratory volume in 1-second (FEV1)	10.3	205	154	342.2	0.98	1.3e-181	ABLIM3 ABO AC073834.3 AC092667.2 AC103965.1 ADAMTS6 ADCY3 AHI1 ANAPC10 AOC1 AP000580.1 AP3B1 ARFGEF2 ARL17B ATP13A2 AXIN2 BCKDHB BCKDK BCL7C BOK BRAF C10orf11 C12orf48 C12orf60 C1QTNF4 C2orf52 CACFD1 CAMLG CCDC126 CCDC171 CCDC87 CD79B CDC123 CDK6 CDO1 CENPW CEP120 CHMP1A CLEC18A CLK3 CLUAP1 CMIP COG4 CRIPAK CTA-85E5.10 CTB-36H16.2 CTD-3074O7.12 CTD-3074O7.5 CTD-3076O17.1 CXCR2 CYB561 CYBRD1 DARS DCAF16 DCXR DDX27 DDX42 DHDDS DIRAS3 DLEU2 DLG1 DLG5 DNAJC9-AS1 DOK7 EBPL EFEMP1 EIF2AK4 EML3 ERCC6L2 EYA2 FAM136A FAM26F FAM35A FER FHL3 FILIP1 FNDC3B FOXP1 GALNT12 GDF5 GSDMC GSK3A H1FX HABP4 HAPLN3 HMBS HORMAD2 HP HSD3B7 IGFBP3 ILF3-AS1 INTS12 IPO8 JAG1 KANSL1 KIAA1468 LDHA LEMD3 LIME1 LOC285733 LOC644172 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 LRRC37A4 MAN2C1 MAP3K1 MFGE8 MFSD10 MGC57346 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTMR3 MTTP MYO9A NARFL NCAPG NCOA1 NDST2 NFAT5 NOA1 NOB1 NOV NUDC NUDT3 OTUD4 PACSIN1 PDXDC2 PIAS4 PLCD3 PLEKHM1P PNKD PPA2 PRPS1P2 PSMA4 PTCH1 QSOX2 RAB24 RAD9A RIN3 RNF123 RP11-1055B8.4 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-538P18.2 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RP11-967K21.1 RP5-966M1.6 RPL10A RPS20 RPS6KA1 RPS6KB2 RSPH6A SAR1B SCMH1 SERPINF1 SF3B2 SLC25A21 SLC38A2 SLCO1C1 SMARCD2 SNAI3-AS1 STX1B STX4 SURF1 SUSD5 TCP11 TCP11L1 TEAD3 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 TULP4 U91328.21 UBXN2A VKORC1 WAC-AS1 WHAMM WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF169 ZNF213 ZNF438 ZNF500 ZNF76
Pulse rate	1.2	2	2	4.4	0.00	1.0e+00	CEP120 ZBTB38
Happiness	1.2	1	0	0.0	0.00	1.0e+00	ZFAS1
Qualifications: A levels/AS levels or equivalent	1.4	4	0	0.0	0.94	6.2e-02	DCAF16 GDF5 LRRC37A2 RNF123
Mouth/teeth dental problems: Dentures	1.4	3	0	0.0	0.00	1.0e+00	ADCY3 PSMA4 RP11-1055B8.4
Asthma	1.7	5	3	6.7	-0.67	1.4e-01	AAGAB AHI1 CTD-3074O7.12 U91328.21 ZNF76
Medication: Ibuprofen (e.g. Nurofen)	1.3	1	0	0.0	0.00	1.0e+00	U91328.21
Medication: Cholesterol lowering	1.6	3	1	2.2	0.00	1.0e+00	ABO HP NOP58
Lung cancer (father)	1.3	1	1	2.2	0.00	1.0e+00	PSMA4
Illnesses of mother	1.3	1	0	0.0	0.00	1.0e+00	ATP5G1
Forced expiratory volume in 1-second (FEV1), Best measure	9.8	180	115	255.6	0.98	1.8e-154	ABLIM3 ABO AC073834.3 AC092667.2 AC103965.1 ADAMTS6 ADCY3 AHI1 ANAPC10 AOC1 AP3B1 ARFGEF2 ARL17B ATP13A2 AXIN2 BCKDHB BCKDK BCL7C BOK BRAF C10orf11 C12orf48 C12orf60 C1QTNF4 C2orf52 C2orf54 CACFD1 CAMLG CCDC87 CD79B CDC123 CDK6 CDO1 CENPW CEP120 CLEC18A CLK3 CLUAP1 CMIP COG4 CRIPAK CTA-85E5.10 CTB-36H16.2 CTD-3074O7.12 CTD-3076O17.1 CXCR2 CYB561 CYBRD1 DARS DCAF16 DCXR DDX27 DDX42 DHDDS DIRAS3 DLEU2 DLG1 DLG5 DNAJC9-AS1 EBPL EFEMP1 EML3 ERCC6L2 FAM136A FAM26F FER FEZ2 FHL3 FILIP1 FNDC3B FOXP1 GALNT12 GDF5 GSDMC GSK3A H1FX HABP4 HAPLN3 HORMAD2 HSD3B7 ILF3-AS1 INTS12 IPO8 JAG1 KANSL1 KIAA1468 LEMD3 LIME1 LOC285733 LOC644172 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 LRRC37A4 MAN2C1 MGC57346 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTMR3 MTTP MYO1F MYO9A NCAPG NCOA1 NDST2 NFAT5 NOA1 NOB1 NUDC OTUD4 PACSIN1 PDXDC2 PIAS4 PLCD3 PLEKHM1P PNKD PPA2 PSMA4 QSOX2 RAB24 RAD9A RIN3 RNF123 RP11-1055B8.4 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-443B20.1 RP11-538P18.2 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RP11-967K21.1 RP11-977G19.11 RP5-966M1.6 RPL10A RPS20 RPS6KA1 SAR1B SCMH1 SERPINF1 SHKBP1 SLC25A21 SLC38A2 SMARCD2 SNAI3-AS1 STX1B STX4 TCP11 TCP11L1 TEAD3 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 U91328.21 UBXN2A VKORC1 WAC-AS1 WHAMM WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF169 ZNF213 ZNF438 ZNF500 ZNF76
Impedance of arm (left)	2.1	42	28	62.2	0.26	7.5e-02	AC103965.1 AOC1 ATP13A2 BCKDK CD79B CENPW CEP120 CTD-3076O17.1 EFEMP1 EML3 FER FEZ2 GNA12 GPR126 KANSL1 LOXL1-AS1 LRRC37A LRRC37A2 MAP3K1 MFGE8 MGC57346 MRPL42 MST1L MST1P2 MTERFD2 NUDT3 PACSIN1 PASK PLK1S1 RIN3 RP11-108M9.5 RP11-179B2.2 RP11-182J1.14 RP11-73O6.3 RP5-966M1.6 RPL10A RPS20 SAR1B SCMH1 SHKBP1 SLC38A2 TBX6
Arm fat mass (right)	2.2	30	22	48.9	-0.13	4.7e-01	AAGAB AC092667.2 ADCY3 AP3B1 BCKDK C1QTNF4 CCDC171 CCDC87 CDK6 CEP120 CLEC18A FEZ2 FOXP1 HSD3B7 LIME1 NOB1 NUDT3 OTUD4 PACSIN1 PDXDC2 PIAS4 PTRHD1 RP11-179B2.2 RP11-443B20.1 RP11-73O6.3 RPL10A TBX6 TP53INP2 VKORC1 ZBTB38
Trunk predicted mass	7.3	126	99	220.0	0.94	2.5e-68	ACPL2 ADCY3 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP13A2 ATP5G1 AXIN2 BCKDHB BOK C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 C9orf3 CCDC47 CD79B CDK6 CENPW CEP120 CHMP1A CRIPAK CSE1L CXCR2 CYB561 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FAM136A FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MST1L MTMR3 MYO1F MYO9A NARFL NCAPG NCOA1 NDUFB2 NMBR NOA1 NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 PTRHD1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SNAI3-AS1 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF213 ZNF500 ZNF76
Standing height	10.7	197	173	384.4	0.94	8.2e-111	AAGAB AC103965.1 ACPL2 ADAMTS6 ADCY3 ANAPC10 ANKRD13B ANKRD9 AOC1 AP000580.1 AP3B1 ARFGEF2 ARMS2 ATP13A2 ATP5G1 AXIN2 BCKDHB BOK BRAF C12orf60 C1QTNF4 C20orf199 C2orf52 C9orf3 CAMLG CCDC126 CCDC47 CCDC87 CD79B CDK6 CDO1 CENPW CEP120 CHMP1A CLEC18A CLK3 CMIP COG4 CRIPAK CROCC CSE1L CTA-85E5.10 CTD-3074O7.12 CTD-3074O7.5 CTD-3076O17.1 CXCR2 CYB561 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DMPK DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 ERC1 ERCC6L2 ESPNP FAM136A FAM26F FAM35A FER FEZ2 FHL3 FILIP1 FNDC3B GDF5 GNA12 GPR126 GSDMC GSK3A H1FX HABP4 HAPLN3 HMBS HORMAD2 HP IGFBP3 ILF3-AS1 IPO8 JAG1 KCNK7 KIAA1468 KLHL7 LDHA LEMD3 LOC285733 LOXL1-AS1 LRRC37A2 MAN2C1 MAP3K1 MFGE8 MFSD10 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTERFD2 MTMR3 MTTP MYO1F MYO9A NARFL NCAPG NCOA1 NDUFB2 NFAT5 NMBR NOA1 NOB1 NOP58 NOV NUDC NUDT3 OTUD4 PACSIN1 PASK PDXDC2 PIAS4 PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 PTRHD1 QSOX2 RAB24 RAD9A RCN2 RNF40 RP11-1055B8.4 RP11-108M9.5 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-538P18.2 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RP11-977G19.11 RP5-966M1.6 RPL10A RPS20 RPS6KA1 RPS6KB2 SAR1B SCMH1 SEPT2 SERPINF1 SF3B2 SIK3 SLC25A21 SLC38A2 SLCO1C1 SMARCD2 SNAI3-AS1 SUSD5 TBX6 TCP11 TEAD3 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 WAC-AS1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZNF169 ZNF213 ZNF500 ZNF76
Breastfed as a baby	1.2	1	0	0.0	0.00	1.0e+00	RCN2
Tense / 'highly strung'	1.4	5	0	0.0	0.99	7.3e-04	BCKDK BCL7C HSD3B7 STX1B STX4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2	0	0.0	0.00	1.0e+00	CCDC87 U91328.21
Hair/balding pattern: Pattern 4	3.1	14	12	26.7	0.22	4.0e-01	ARL17B C10orf11 CENPW CTB-36H16.2 DLG5 FAM136A KANSL1 LOC285733 LOC644172 LRRC37A LRRC37A2 LRRC37A4 MGC57346 ZBTB38
Birth weight of first child	2.5	11	7	15.6	0.97	2.2e-09	ANAPC10 DCAF16 DCXR FEZ2 IPO8 OTUD4 PPA2 RPL10A TEAD3 WNT4 ZBTB38
Peak expiratory flow (PEF)	5.0	49	26	57.8	0.95	4.6e-29	ABO ANAPC10 ARFGEF2 ARL17B BOK C10orf11 C12orf48 CACFD1 CCDC87 CD79B CDC123 CLEC18A CTA-85E5.10 CTD-3074O7.12 DCAF16 DHDDS DLEU2 DLG1 EFEMP1 GDF5 GSDMC H1FX KANSL1 LRRC37A LRRC37A2 MPHOSPH6 MRGPRF NCAPG NOA1 OTUD4 PIAS4 PNKD PPA2 PRPS1P2 RAD9A RNF123 RP11-179B2.2 RP11-425D10.10 RP11-65J21.3 RPL10A RPS6KA1 SF3B2 TCP11 TCP11L1 TP53INP2 TRIM63 UBXN2A ZHX2 ZNF76
Qualifications: O levels/GCSEs or equivalent	1.3	1	0	0.0	0.00	1.0e+00	ZNF500
Blood clot in the leg (DVT)	1.5	2	2	4.4	0.00	1.0e+00	ABO CACFD1
Medication: Paracetamol	1.7	5	4	8.9	-0.64	1.7e-01	ARL17B KANSL1 LRRC37A LRRC37A2 U91328.21
Headache pain in last month	1.6	7	5	11.1	-0.75	3.3e-02	ARL17B KANSL1 LRRC37A LRRC37A2 MGC57346 NOA1 U91328.21
Hypothyroidism/myxoedema (self-reported)	1.2	6	3	6.7	-0.40	4.4e-01	AHI1 HORMAD2 MTMR3 PLEKHA1 SEPT2 SIK3
Medication: Ventolin 100micrograms inhaler	1.1	1	0	0.0	0.00	1.0e+00	AAGAB
Birth weight	2.8	19	7	15.6	0.90	2.4e-09	ANAPC10 C1QTNF4 CDK6 CENPW DCAF16 EDNRB GNA12 GPR126 HORMAD2 NCAPG PPA2 RP11-425D10.10 RP11-435O5.5 RP11-73O6.3 TEAD3 TRA2A TULP4 UBXN2A WNT4
Chronic bronchitis/emphysema (mother)	1.5	1	1	2.2	0.00	1.0e+00	PSMA4
High blood pressure (siblings)	1.5	1	1	2.2	0.00	1.0e+00	BCKDK
Forced vital capacity (FVC), Best measure	12.2	246	202	448.9	1.00	2.7e-321	AAGAB ABLIM3 ABO AC073834.3 AC092667.2 AC103965.1 ACPL2 ADAMTS6 ADCY3 AHI1 ANAPC10 ANKRD13B AOC1 AP000580.1 AP3B1 ARFGEF2 ARL17B ARMS2 ATP13A2 ATP5G1 AXIN2 BCKDHB BCKDK BCL7C BOK BRAF C10orf11 C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 C2orf54 C9orf3 CACFD1 CAMLG CCDC126 CCDC171 CCDC47 CCDC87 CD79B CDC123 CDK5RAP3 CDK6 CDO1 CENPW CEP120 CHMP1A CLEC18A CLK3 CLUAP1 CMIP COG4 CRIPAK CROCC CSE1L CTA-85E5.10 CTB-36H16.2 CTC-228N24.3 CTD-3074O7.12 CTD-3074O7.5 CTD-3076O17.1 CXCR2 CYB561 CYBRD1 DARS DCAF16 DCXR DDX27 DDX42 DHDDS DIRAS3 DLEU2 DLG1 DLG5 DMPK DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EML3 ERC1 ERCC6L2 ESPNP EYA2 FAM136A FAM26F FER FEZ2 FHL3 FILIP1 FNDC3B FOXP1 GALNT12 GDF5 GNA12 GPR126 GSDMC GSK3A H1FX HABP4 HAPLN3 HMBS HORMAD2 HP HSD3B7 ILF3-AS1 INTS12 IPO8 JAG1 KANSL1 KCNK7 KIAA1468 LDHA LEMD3 LIME1 LMCD1 LOC285733 LOC644172 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 LRRC37A4 MAN2C1 MFGE8 MGC57346 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTERFD2 MTMR3 MTTP MYO1F MYO9A NARFL NCAPG NCOA1 NDST2 NDUFB2 NFAT5 NMBR NOA1 NOB1 NOP58 NOV NUDC NUDT3 OTUD4 PACSIN1 PASK PDXDC2 PIAS4 PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PSMA4 PTCH1 PTRHD1 QSOX2 RAB24 RAD9A RCN2 RIN3 RNF123 RNF40 RP11-1055B8.4 RP11-108M9.5 RP11-109N23.6 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-538P18.2 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RP11-967K21.1 RP11-977G19.11 RP5-966M1.6 RPL10A RPS20 RPS6KA1 RPS6KB2 RSPH6A SAR1B SCMH1 SEPT2 SERPINF1 SF3B2 SHKBP1 SHROOM3 SIK3 SLC25A21 SLC38A2 SLCO1C1 SMARCD2 SNAI3-AS1 SNRPD2 STX1B STX4 SURF1 SUSD5 TBX6 TCP11 TCP11L1 TEAD3 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 U91328.21 UBXN2A UIMC1 USP14 VKORC1 WAC-AS1 WHAMM WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF169 ZNF213 ZNF438 ZNF500 ZNF76
Body fat percentage	2.7	38	23	51.1	-0.55	1.0e-04	AAGAB AC073834.3 AC103965.1 ADCY3 ANKRD13B AP3B1 ARFGEF2 BCKDK C1QTNF4 CCDC171 CD79B CENPW CLEC18A CTD-3076O17.1 DARS DCAF16 DLG1 EML3 FEZ2 FOXP1 HABP4 HMBS HSD3B7 LIME1 LRRC37A2 NOB1 NOV PIAS4 PTRHD1 RIN3 RP11-182J1.14 RP11-443B20.1 SAR1B STX1B TEAD3 VKORC1 ZBTB38 ZFAS1
Leg fat percentage (right)	3.0	46	26	57.8	-0.88	4.1e-18	AAGAB AC073834.3 ADCY3 ANKRD13B ARFGEF2 BCKDK BCL7C C1QTNF4 CCDC171 CD79B CDK5RAP3 CENPW CLEC18A CTC-228N24.3 DARS DCAF16 DDX27 DDX42 DLG1 FOXP1 GDF5 GSK3A HABP4 HMBS HSD3B7 LIME1 NCAPG NOB1 NOP58 NOV PIAS4 PIGF PLEKHM1P PTRHD1 RIN3 RP11-182J1.14 RP11-435O5.5 RP11-443B20.1 SAR1B SMARCD2 SNAI3-AS1 STX1B STX4 TEAD3 VKORC1 ZFAS1
Arm fat-free mass (right)	6.0	104	84	186.7	0.93	3.4e-54	ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 CD79B CDK6 CENPW CEP120 CHMP1A CRIPAK CXCR2 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F NARFL NCAPG NCOA1 NDUFB2 NMBR NOV NUDT3 OTUD4 PACSIN1 PLEKHA1 PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 UBXN2A UIMC1 VKORC1 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF76
Comparative body size at age 10	4.0	16	6	13.3	-0.78	1.7e-05	ADCY3 AP3B1 BCKDK C1QTNF4 CMIP DMPK ERCC6L2 HSD3B7 KANSL1 NCOA1 PTRHD1 RP11-443B20.1 STX1B U91328.21 UIMC1 VKORC1
Number of full brothers	1.2	1	0	0.0	0.00	1.0e+00	LRRC37A2
Worry too long after embarrassment	1.6	3	0	0.0	0.00	1.0e+00	AHI1 LRRC37A2 PPA2
Wheeze or whistling in the chest in last year	1.7	3	1	2.2	0.00	1.0e+00	CCDC171 LIME1 NDST2
Health satisfaction	1.1	1	0	0.0	0.00	1.0e+00	CCDC87
Qualifications: College or University degree	1.5	16	7	15.6	0.88	3.0e-06	DCAF16 DDX42 EML3 FOXP1 GDF5 HABP4 KANSL1 LOC644172 LRRC37A LRRC37A2 LRRC37A4 MFSD10 PPA2 RNF123 RP11-1055B8.4 SMARCD2
Medication for pain relief, constipation, heartburn	1.7	4	2	4.4	-0.56	3.3e-01	LRRC37A LRRC37A2 PLCD3 U91328.21
Medication: Blood pressure	1.4	1	0	0.0	0.00	1.0e+00	DCAF16
Mean time to correctly identify matches	1.4	4	0	0.0	0.66	3.4e-01	ARFGEF2 CSE1L DDX27 PIAS4
Whole body fat mass	2.4	40	28	62.2	0.23	1.3e-01	AAGAB AC103965.1 ADCY3 ANAPC10 AP3B1 BCKDK C1QTNF4 CCDC171 CDK6 CEP120 CLEC18A CTD-3076O17.1 DLG1 E2F1 EFEMP1 FEZ2 FOXP1 GDF5 GNA12 GPR126 H1FX HSD3B7 LIME1 LRRC37A2 NOB1 NUDT3 OTUD4 PACSIN1 PIAS4 PTRHD1 RAD9A RP11-179B2.2 RP11-182J1.14 RP11-443B20.1 RP11-73O6.3 RPL10A TBX6 TP53INP2 VKORC1 ZBTB38
Leg fat mass (right)	2.2	28	22	48.9	-0.13	4.9e-01	AAGAB ADCY3 AP3B1 BCKDK C1QTNF4 CCDC171 CDK6 CLEC18A DARS FOXP1 HSD3B7 LIME1 NOB1 NUDT3 OTUD4 PACSIN1 PIAS4 PTRHD1 RAD9A RP11-179B2.2 RP11-182J1.14 RP11-443B20.1 RP11-73O6.3 RPL10A SAR1B TBX6 VKORC1 ZBTB38
Arm predicted mass (right)	6.0	101	86	191.1	0.93	2.1e-52	ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CXCR2 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PLEKHA1 PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF76
Pulse rate, automated reading	1.5	13	6	13.3	-0.29	3.1e-01	AC103965.1 CEP120 DARS EML3 FNDC3B HABP4 MYO9A NCOA1 RNF40 RP11-1055B8.4 TRIM63 ZBTB38 ZNF500
Alcohol intake frequency.	1.5	10	7	15.6	-0.79	3.9e-03	AC092667.2 C1QTNF4 FOXP1 KANSL1 LRRC37A LRRC37A2 PPA2 TBX6 TMED6 UBXN2A
Comparative height size at age 10	9.0	145	122	271.1	0.95	2.8e-89	AAGAB AC103965.1 ACPL2 ADAMTS6 ADCY3 ANAPC10 ANKRD13B ANKRD9 AOC1 AP3B1 ARFGEF2 ARMS2 ATP13A2 ATP5G1 AXIN2 BCKDHB BOK C12orf48 C12orf60 C1QTNF4 C20orf199 CCDC126 CCDC47 CD79B CDK6 CDO1 CENPW CEP120 CHMP1A CMIP CRIPAK CROCC CSE1L CTA-85E5.10 CTD-3074O7.12 CTD-3074O7.5 CTD-3076O17.1 CXCR2 CYB561 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DMPK DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 ERCC6L2 ESPNP FAM136A FAM26F FER FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 IGFBP3 ILF3-AS1 KLHL7 LOXL1-AS1 LRRC37A2 MAN2C1 MAP3K1 MFGE8 MPHOSPH6 MRGPRF MRPL42 MST1L MST1P2 MTMR3 MTTP MYO1F MYO9A NARFL NCAPG NCOA1 NMBR NOV OTUD4 PACSIN1 PIAS4 PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PNKD PPA2 PTCH1 PTRHD1 QSOX2 RAB24 RAD9A RP11-108M9.5 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-435O5.5 RP11-443B20.1 RP11-690I21.1 RP11-73O6.3 RP5-966M1.6 RPL10A RPS20 RPS6KA1 RPS6KB2 RSPH6A SCMH1 SEPT2 SERPINF1 SLC25A21 SMARCD2 SUSD5 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 U91328.21 UBXN2A UIMC1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZNF169 ZNF500 ZNF76
Suffer from 'nerves'	1.2	1	1	2.2	0.00	1.0e+00	C1QTNF4
Overall health rating	1.6	12	4	8.9	-0.94	8.1e-06	AP000580.1 BCKDK CCDC87 CTD-3074O7.12 CTD-3074O7.5 DCAF16 FOXP1 MFSD10 PRPS1P2 RP11-1055B8.4 SNRPD2 VKORC1
Family relationship satisfaction	1.3	1	0	0.0	0.00	1.0e+00	ZFAS1
Knee pain experienced in last month	1.6	1	1	2.2	0.00	1.0e+00	GDF5
Hypertension (Self-reported)	1.5	9	4	8.9	-0.40	2.0e-01	ADCY3 BCKDK DCAF16 LRRC37A2 NCAPG NCOA1 PIAS4 RP11-1055B8.4 RP11-538P18.2
Forced expiratory volume in 1-second (FEV1), predicted	7.2	64	39	86.7	0.97	2.4e-48	AC103965.1 ADCY3 ANAPC10 ATP13A2 ATP5G1 BOK C1QTNF4 CD79B CDK6 CENPW CTD-3076O17.1 CYBRD1 DCAF16 DDX42 DLEU2 E2F1 EBPL EFEMP1 ERCC6L2 FER FHL3 GDF5 GNA12 GPR126 GSDMC H1FX ILF3-AS1 LEMD3 LOXL1-AS1 MAN2C1 MFGE8 MRPL42 MST1L MST1P2 MYO1F MYO9A NARFL NCAPG OTUD4 PACSIN1 PIP4K2B PTCH1 RAB24 RAD9A RP11-182J1.14 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-73O6.3 RP11-977G19.11 RP5-966M1.6 RPL10A SCMH1 SMARCD2 TCP11 TEAD3 TMEM180 TP53INP2 TRA2A UIMC1 ZBTB38 ZHX2 ZNF500 ZNF76
Whole body fat-free mass	6.5	116	94	208.9	0.93	1.4e-59	ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 CCDC47 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CXCR2 CYB561 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MTMR3 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SNAI3-AS1 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF213 ZNF500 ZNF76
Leg fat-free mass (right)	5.3	102	74	164.4	0.92	1.4e-50	ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DDX42 DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MTMR3 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-73O6.3 RPL10A RPS20 SCMH1 SEPT2 SLC38A2 SMARCD2 SNAI3-AS1 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF500 ZNF76
Arm fat percentage (left)	3.0	36	26	57.8	-0.79	1.4e-10	AAGAB ABO ADCY3 ANKRD13B AP3B1 ARFGEF2 BCKDK C1QTNF4 CCDC171 CCDC87 CD79B CENPW CLEC18A CTD-3074O7.5 DCAF16 DDX27 DLG1 FOXP1 HABP4 HSD3B7 LIME1 NCAPG NFAT5 NOB1 NOP58 NOV PDXDC2 PIAS4 PIGF PTRHD1 RP11-443B20.1 SAR1B TBX6 TEAD3 VKORC1 ZFAS1
Average weekly red wine intake	1.2	1	1	2.2	0.00	1.0e+00	FOXP1
Handedness (chirality/laterality): Left-handed	1.3	1	1	2.2	0.00	1.0e+00	LRRC37A2
Mood swings	1.6	7	3	6.7	-0.86	6.7e-03	AP000580.1 ARL17B GPR126 KANSL1 LRRC37A LRRC37A2 RP11-179B2.2
Loneliness, isolation	1.5	4	0	0.0	0.98	1.7e-02	ARFGEF2 C1QTNF4 CSE1L DDX27
Long-standing illness, disability or infirmity	1.6	1	1	2.2	0.00	1.0e+00	CCDC171
Diabetes diagnosed by doctor	1.6	2	0	0.0	0.00	1.0e+00	CENPW CLEC18A
Qualifications: nursing, teaching	1.2	1	0	0.0	0.00	1.0e+00	AXIN2
Mouth/teeth dental problems: Mouth ulcers	1.5	4	2	4.4	-0.97	7.3e-03	ARL17B KANSL1 LRRC37A LRRC37A2
Medication for cholesterol	1.6	1	0	0.0	0.00	1.0e+00	ZNF500
Back pain experienced in last month	1.4	1	1	2.2	0.00	1.0e+00	ARMS2
Breast cancer (self-reported)	1.2	1	0	0.0	0.00	1.0e+00	KLHL7
Asthma (self-reported)	1.7	5	3	6.7	-0.65	1.6e-01	AAGAB AHI1 CTD-3074O7.12 U91328.21 ZNF76
Osteoporosis (self-reported)	1.2	1	0	0.0	0.00	1.0e+00	MRGPRF
Smoking status: Current	1.3	2	1	2.2	0.00	1.0e+00	LIME1 PRPS1P2
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.2	40	25	55.6	0.90	6.1e-16	AC073834.3 ARL17B BCKDK BCL7C BOK C10orf11 CDC123 CEP120 CLEC18A CLUAP1 CTA-85E5.10 DHDDS EML3 GPR126 HSD3B7 INTS12 JAG1 KANSL1 LIME1 LRRC37A LRRC37A2 MGC57346 NDST2 NOB1 PPA2 PSMA4 QSOX2 RIN3 RNF123 RP11-538P18.2 RP11-967K21.1 RPL10A STX1B STX4 TEAD3 TRIM63 U91328.21 VKORC1 WHAMM WNT4
Whole body water mass	6.5	116	95	211.1	0.93	2.4e-59	ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C1QTNF4 C20orf199 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CXCR2 CYB561 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MTMR3 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SNAI3-AS1 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF213 ZNF500 ZNF76
Leg predicted mass (right)	5.3	102	74	164.4	0.92	1.1e-50	ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DDX42 DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MTMR3 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-73O6.3 RPL10A RPS20 SCMH1 SEPT2 SLC38A2 SMARCD2 SNAI3-AS1 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF500 ZNF76
Arm fat mass (left)	2.3	31	23	51.1	-0.07	6.9e-01	AAGAB ADCY3 AP3B1 BCKDK C1QTNF4 CCDC171 CCDC87 CDK6 CEP120 CLEC18A FEZ2 FOXP1 GDF5 GNA12 HSD3B7 LIME1 NOB1 NUDT3 OTUD4 PACSIN1 PDXDC2 PIAS4 PTRHD1 RP11-179B2.2 RP11-443B20.1 RP11-73O6.3 RPL10A TBX6 TP53INP2 VKORC1 ZBTB38
Number of self-reported non-cancer illnesses	1.7	3	1	2.2	0.00	1.0e+00	AAGAB CCDC87 CTA-85E5.10
Average weekly champagne plus white wine intake	1.4	3	0	0.0	0.97	3.4e-02	KANSL1 LRRC37A LRRC37A2
Miserableness	1.3	5	2	4.4	-0.98	6.0e-04	HORMAD2 KANSL1 LOXL1-AS1 LRRC37A LRRC37A2
Guilty feelings	1.4	3	0	0.0	0.00	1.0e+00	LRRC37A LRRC37A2 UBXN2A
Medication: Blood pressure	1.4	5	1	2.2	0.51	3.0e-01	ADCY3 CHMP1A LRRC37A2 RP11-1055B8.4 ZNF500
Supplements: Fish oil (including cod liver oil)	1.3	2	0	0.0	0.00	1.0e+00	CCDC87 NFAT5
High cholesterol (Self-reported)	1.9	4	2	4.4	-0.99	5.1e-03	ABO FAM136A NOP58 VKORC1
Medication: Paracetamol	1.6	4	3	6.7	-0.66	2.3e-01	KANSL1 LRRC37A LRRC37A2 U91328.21
Medication: Atorvastatin	1.3	1	0	0.0	0.00	1.0e+00	ABO
Illnesses of father: High blood pressure	1.4	1	0	0.0	0.00	1.0e+00	NCOA1
Ever smoked	1.4	3	1	2.2	0.00	1.0e+00	NOA1 PRPS1P2 PSMA4
Basal metabolic rate	5.8	108	86	191.1	0.92	4.5e-54	ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CXCR2 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DOK7 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FEZ2 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MFGE8 MPHOSPH6 MRGPRF MRPL42 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 TULP4 UBXN2A UIMC1 VKORC1 WNT4 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF500 ZNF76
Leg fat percentage (left)	3.0	43	26	57.8	-0.87	6.6e-17	AAGAB AC073834.3 ADCY3 ANKRD13B ARFGEF2 BCKDK C1QTNF4 CCDC171 CD79B CDK5RAP3 CENPW CLEC18A CTC-228N24.3 DARS DCAF16 DDX27 DDX42 DLG1 FOXP1 GDF5 GSK3A HABP4 HMBS HSD3B7 LIME1 NCAPG NOB1 NOV PIAS4 PIGF PLEKHM1P PTRHD1 RIN3 RP11-182J1.14 RP11-435O5.5 RP11-443B20.1 SAR1B SMARCD2 STX1B STX4 TEAD3 VKORC1 ZFAS1
Arm fat-free mass (left)	5.7	100	80	177.8	0.92	1.2e-50	ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C20orf199 C2orf52 CD79B CDK6 CENPW CEP120 CRIPAK CXCR2 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MTMR3 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PLEKHA1 PLK1S1 PNKD PPA2 PTCH1 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRA2A TRIM63 UBXN2A UIMC1 VKORC1 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF76
Number of operations (self-reported)	1.5	2	1	2.2	0.00	1.0e+00	MTMR3 PPA2
Average weekly beer plus cider intake	1.1	1	0	0.0	0.00	1.0e+00	RNF123
Irritability	1.6	8	5	11.1	-0.30	4.3e-01	ARL17B BCL7C HSD3B7 KANSL1 LRRC37A LRRC37A2 STX1B STX4
Ever had prostate specific antigen (PSA) test	1.4	1	0	0.0	0.00	1.0e+00	ZBTB38
Fractured/broken bones in last 5 years	1.5	3	0	0.0	0.00	1.0e+00	CRIPAK LRRC37A2 VKORC1
Diastolic blood pressure, automated reading	1.6	15	8	17.8	-0.42	8.6e-02	AAGAB ABO ACPL2 BCKDHB CEP120 DARS DCAF16 HSD3B7 JAG1 MYO9A NCAPG NOV RP11-538P18.2 SCMH1 U91328.21
Myopia	1.6	1	1	2.2	0.00	1.0e+00	QSOX2
Vascular/heart problems diagnosed by doctor	1.5	10	2	4.4	0.68	1.0e-02	ADCY3 BCKDK DCAF16 NCAPG NCOA1 NFAT5 PIAS4 RP11-538P18.2 TEAD3 VKORC1
Cholesterol lowering medication	1.8	3	0	0.0	0.00	1.0e+00	ABO ANKRD13B VKORC1
Pain experienced in last month	1.4	2	0	0.0	0.00	1.0e+00	CENPW PRPS1P2
Deep venous thrombosis (DVT) (self-reported)	1.5	2	2	4.4	0.00	1.0e+00	ABO CACFD1
Pack years of smoking	2.3	3	1	2.2	0.00	1.0e+00	CYB561 PIAS4 PSMA4
Impedance of whole body	2.2	50	38	84.4	0.08	5.6e-01	AC103965.1 ADCY3 AOC1 ATP13A2 BCKDK CD79B CDO1 CENPW CEP120 CRIPAK CROCC CTC-228N24.3 CTD-3076O17.1 CYBRD1 EDNRB EFEMP1 EML3 GDF5 GPR126 KANSL1 LOXL1-AS1 LRRC37A LRRC37A2 MAP3K1 MRGPRF MRPL42 MST1L MST1P2 MTERFD2 NUDT3 OTUD4 PACSIN1 PASK PLK1S1 PPA2 RAD9A RIN3 RP11-108M9.5 RP11-179B2.2 RP11-182J1.14 RP11-425D10.10 RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 RPL10A RPS20 SCMH1 SLC38A2 TBX6 VKORC1
Leg fat mass (left)	2.2	30	22	48.9	-0.16	3.6e-01	AAGAB ADCY3 AP3B1 BCKDK C1QTNF4 CCDC171 CDK6 CLEC18A DARS DLG1 FOXP1 HSD3B7 LIME1 NOB1 NUDT3 OTUD4 PACSIN1 PIAS4 PTRHD1 RAD9A RP11-179B2.2 RP11-182J1.14 RP11-443B20.1 RP11-73O6.3 RPL10A SAR1B STX4 TBX6 VKORC1 ZBTB38
Arm predicted mass (left)	5.7	101	80	177.8	0.92	9.4e-51	ACPL2 ANAPC10 AOC1 AP3B1 ARFGEF2 ARMS2 ATP5G1 AXIN2 BCKDHB BCKDK BOK C12orf48 C12orf60 C2orf52 CD79B CDK6 CENPW CEP120 CHMP1A CRIPAK CXCR2 CYBRD1 DCAF16 DDX27 DDX42 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 FHL3 FNDC3B GDF5 GNA12 GPR126 GSDMC H1FX HABP4 HAPLN3 HORMAD2 ILF3-AS1 IPO8 LEMD3 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MYO1F NARFL NCAPG NCOA1 NMBR NOV NUDT3 OTUD4 PACSIN1 PLEKHA1 PLK1S1 PNKD PPA2 PRPS1P2 PTCH1 RAB24 RAD9A RIN3 RP11-179B2.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-65J21.3 RP11-690I21.1 RP11-73O6.3 RPL10A RPS20 RPS6KA1 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 TBX6 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TPCN2 TRA2A TRIM63 UBXN2A UIMC1 VKORC1 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF76

Associations by panel

study	tissue	# hits	% hits/tests	avg chisq
GTEx	Adipose Subcutaneous	65	1.9	4.1
GTEx	Adipose Visceral Omentum	48	2.4	4.4
GTEx	Adrenal Gland	29	2.0	3.9
GTEx	Artery Aorta	62	2.1	4.3
GTEx	Artery Coronary	32	2.7	4.6
GTEx	Artery Tibial	75	2.0	4.1
GTEx	Brain Caudate basal ganglia	15	1.6	3.8
GTEx	Brain Cerebellar Hemisphere	34	2.3	4.3
GTEx	Brain Cerebellum	43	2.2	4.3
GTEx	Brain Cortex	28	2.7	4.4
GTEx	Brain Frontal Cortex BA9	19	2.1	4.2
GTEx	Brain Hippocampus	15	2.9	4.5
GTEx	Brain Hypothalamus	19	3.2	4.5
GTEx	Brain Nucleus accumbens basal ganglia	22	2.5	4.5
GTEx	Brain Putamen basal ganglia	11	1.8	4.1
GTEx	Breast Mammary Tissue	44	2.2	4.4
GTEx	Breast Mammary Tissue (Male)	33	2.8	4.8
GTEx	Breast Mammary Tissue (Female)	31	1.9	4.1
GTEx	Cells EBV-transformed lymphocytes	40	2.8	4.7
GTEx	Cells Transformed fibroblasts	81	1.9	3.9
GTEx	Colon Sigmoid	29	2.0	4.3
GTEx	Colon Transverse	47	2.3	4.2
GTEx	Esophagus Gastroesophageal Junction	33	2.3	4.3
GTEx	Esophagus Mucosa	69	2.1	4.1
GTEx	Esophagus Muscularis	75	2.3	4.4
GTEx	Heart Atrial Appendage	39	2.5	4.6
GTEx	Heart Left Ventricle	31	2.0	4.1
GTEx	Liver	18	2.5	4.3
GTEx	Lung	72	2.5	4.2
GTEx	Muscle Skeletal	46	1.6	3.9
GTEx	Nerve Tibial	90	2.1	4.1
GTEx	Ovary	27	3.0	5.2
GTEx	Pancreas	34	2.1	4.2
GTEx	Pituitary	37	3.3	4.8
GTEx	Prostate	14	1.7	4.0
GTEx	Skin Not Sun Exposed Suprapubic	53	2.2	4.2
GTEx	Skin Sun Exposed Lower leg	73	2.0	4.2
GTEx	Small Intestine Terminal Ileum	14	3.0	5.0
GTEx	Spleen	27	1.9	4.4
GTEx	Stomach	35	2.4	4.3
GTEx	Testis	69	2.2	4.3
GTEx	Thyroid	77	1.9	4.1
GTEx	Uterus	19	3.4	5.1
GTEx	Vagina	15	2.4	4.2
GTEx	Whole Blood	40	2.0	3.9
METSIM	Adipose	60	1.3	3.4
NTR	Blood	39	1.6	3.5
ROSMAP	Brain Pre-frontal Cortex	61	1.4	3.4
YFS	Blood	61	1.3	3.3
CommonMind	Brain Pre-frontal Cortex	68	1.3	3.3
The Cancer Genome Atlas	Bladder Urothelial Carcinoma	27	1.6	3.5
The Cancer Genome Atlas	Breast Invasive Carcinoma	66	1.5	3.5
The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	18	1.6	3.7
The Cancer Genome Atlas	Colon Adenocarcinoma	30	1.5	3.5
The Cancer Genome Atlas	Esophageal Carcinoma	15	2.2	4.0
The Cancer Genome Atlas	Glioblastoma Multiforme	24	2.3	4.0
The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	47	1.7	3.6
The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	65	1.6	3.5
The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	27	1.3	3.4
The Cancer Genome Atlas	Brain Lower Grade Glioma	74	1.7	3.5
The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	15	1.4	3.5
The Cancer Genome Atlas	Lung Adenocarcinoma	47	1.6	3.5
The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	42	1.7	3.5
The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	24	1.5	3.4
The Cancer Genome Atlas	Pancreatic Adenocarcinoma	20	1.2	3.4
The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	23	1.7	3.6
The Cancer Genome Atlas	Prostate Adenocarcinoma	65	1.4	3.5
The Cancer Genome Atlas	Rectum Adenocarcinoma	10	1.4	3.7
The Cancer Genome Atlas	Soft Tissue Sarcoma	25	2.3	3.8
The Cancer Genome Atlas	Skin Cutaneous Melanoma	10	1.9	3.7
The Cancer Genome Atlas	Stomach Adenocarcinoma	23	1.4	3.4
The Cancer Genome Atlas	Testicular Germ Cell Tumors	14	1.1	3.2
The Cancer Genome Atlas	Thyroid Carcinoma	78	1.5	3.4
The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	10	2.0	3.9