Best TWAS P=1.15e-09 · Best GWAS P=4.38e-08 conditioned to 2.75e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | EIF2AK4 | 0.31 | 0.08 | enet | 29 | 0.17 | 1.8e-09 | -3.4 | 6.1 | 1.1e-09 | -0.14 | 0.66 | 0.17 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | EIF2AK4 | 0.33 | 0.12 | enet | 49 | 0.21 | 8.2e-16 | -1.5 | 5.2 | 1.9e-07 | -0.14 | 0.84 | 0.00 | FALSE |