[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) :

chr17:36,211,659-37,597,185

Best TWAS P=2.27e-09 · Best GWAS P=8.68e-10 conditioned to 0.00353

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellum PCGF2 0.25 0.29 lasso 3 0.26 2.4e-08 -6.0 6.0 2.3e-09 -0.66 0.00 0.99 TRUE
2 GTEx Colon Transverse PCGF2 0.29 0.21 lasso 5 0.20 6.2e-10 -5.3 -5.2 2.0e-07 0.51 0.17 0.82 FALSE
3 GTEx Heart Atrial Appendage PCGF2 0.18 0.13 lasso 3 0.09 6.1e-05 -5.3 -5.3 1.3e-07 0.52 0.09 0.71 FALSE
4 GTEx Lung PCGF2 0.25 0.17 lasso 7 0.17 4.8e-13 -5.3 -5.3 1.4e-07 0.52 0.17 0.83 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic PCGF2 0.39 0.23 lasso 4 0.21 6.9e-12 -5.3 -5.2 1.9e-07 0.51 0.14 0.86 FALSE
6 GTEx Skin Sun Exposed Lower leg PCGF2 0.36 0.30 lasso 7 0.32 1.3e-26 -5.3 -5.8 7.3e-09 0.61 0.14 0.86 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PCGF2 0.13 0.06 blup 37 0.09 7.0e-10 -5.3 -5.2 1.9e-07 0.55 0.01 0.99 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PCGF2 0.24 0.15 lasso 5 0.18 2.2e-19 -5.3 -5.4 6.7e-08 0.49 0.18 0.82 FALSE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PCGF2 0.05 0.03 lasso 3 0.04 1.0e-05 -4.3 -5.3 1.1e-07 0.49 0.03 0.95 FALSE