Best TWAS P=2.27e-09 · Best GWAS P=8.68e-10 conditioned to 0.00353
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellum | PCGF2 | 0.25 | 0.29 | lasso | 3 | 0.26 | 2.4e-08 | -6.0 | 6.0 | 2.3e-09 | -0.66 | 0.00 | 0.99 | TRUE |
2 | GTEx | Colon Transverse | PCGF2 | 0.29 | 0.21 | lasso | 5 | 0.20 | 6.2e-10 | -5.3 | -5.2 | 2.0e-07 | 0.51 | 0.17 | 0.82 | FALSE |
3 | GTEx | Heart Atrial Appendage | PCGF2 | 0.18 | 0.13 | lasso | 3 | 0.09 | 6.1e-05 | -5.3 | -5.3 | 1.3e-07 | 0.52 | 0.09 | 0.71 | FALSE |
4 | GTEx | Lung | PCGF2 | 0.25 | 0.17 | lasso | 7 | 0.17 | 4.8e-13 | -5.3 | -5.3 | 1.4e-07 | 0.52 | 0.17 | 0.83 | FALSE |
5 | GTEx | Skin Not Sun Exposed Suprapubic | PCGF2 | 0.39 | 0.23 | lasso | 4 | 0.21 | 6.9e-12 | -5.3 | -5.2 | 1.9e-07 | 0.51 | 0.14 | 0.86 | FALSE |
6 | GTEx | Skin Sun Exposed Lower leg | PCGF2 | 0.36 | 0.30 | lasso | 7 | 0.32 | 1.3e-26 | -5.3 | -5.8 | 7.3e-09 | 0.61 | 0.14 | 0.86 | FALSE |
7 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | PCGF2 | 0.13 | 0.06 | blup | 37 | 0.09 | 7.0e-10 | -5.3 | -5.2 | 1.9e-07 | 0.55 | 0.01 | 0.99 | FALSE |
8 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PCGF2 | 0.24 | 0.15 | lasso | 5 | 0.18 | 2.2e-19 | -5.3 | -5.4 | 6.7e-08 | 0.49 | 0.18 | 0.82 | FALSE |
9 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | PCGF2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 1.0e-05 | -4.3 | -5.3 | 1.1e-07 | 0.49 | 0.03 | 0.95 | FALSE |