[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) :

chr17:29,482,878-31,275,580

Best TWAS P=1.52e-07 · Best GWAS P=1.63e-07 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial UTP6 0.07 0.02 lasso 3 0.02 5.9e-03 5.1 -5.1 3.0e-07 -0.85 0.03 0.94 FALSE
2 GTEx Breast Mammary Tissue CTC-542B22.2 0.07 0.01 enet 8 0.03 1.7e-02 5.1 5.2 1.9e-07 0.87 0.04 0.88 FALSE
3 GTEx Cells EBV-transformed lymphocytes RHOT1 0.10 0.01 lasso 13 0.01 1.1e-01 5.2 -5.2 2.4e-07 -0.85 0.03 0.75 FALSE
4 GTEx Cells Transformed fibroblasts CTC-542B22.2 0.12 0.03 lasso 6 0.05 2.1e-04 5.2 5.2 1.8e-07 0.96 0.02 0.97 FALSE
5 GTEx Esophagus Mucosa RHOT1 0.07 0.00 lasso 14 0.00 1.5e-01 5.1 -5.2 2.4e-07 -0.88 0.03 0.52 FALSE
6 GTEx Testis COPRS 0.31 0.26 enet 11 0.28 4.3e-13 5.2 5.2 1.7e-07 0.97 0.03 0.97 FALSE
7 The Cancer Genome Atlas Lung Adenocarcinoma LRRC37B 0.02 0.02 blup 23 0.02 3.5e-03 5.1 5.1 3.1e-07 0.86 0.02 0.85 FALSE
8 The Cancer Genome Atlas Prostate Adenocarcinoma C17orf79 0.07 0.04 lasso 2 0.03 1.5e-04 5.2 -5.2 1.5e-07 -0.99 0.00 0.99 TRUE