Best TWAS P=1.52e-07 · Best GWAS P=1.63e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | UTP6 | 0.07 | 0.02 | lasso | 3 | 0.02 | 5.9e-03 | 5.1 | -5.1 | 3.0e-07 | -0.85 | 0.03 | 0.94 | FALSE |
| 2 | GTEx | Breast Mammary Tissue | CTC-542B22.2 | 0.07 | 0.01 | enet | 8 | 0.03 | 1.7e-02 | 5.1 | 5.2 | 1.9e-07 | 0.87 | 0.04 | 0.88 | FALSE |
| 3 | GTEx | Cells EBV-transformed lymphocytes | RHOT1 | 0.10 | 0.01 | lasso | 13 | 0.01 | 1.1e-01 | 5.2 | -5.2 | 2.4e-07 | -0.85 | 0.03 | 0.75 | FALSE |
| 4 | GTEx | Cells Transformed fibroblasts | CTC-542B22.2 | 0.12 | 0.03 | lasso | 6 | 0.05 | 2.1e-04 | 5.2 | 5.2 | 1.8e-07 | 0.96 | 0.02 | 0.97 | FALSE |
| 5 | GTEx | Esophagus Mucosa | RHOT1 | 0.07 | 0.00 | lasso | 14 | 0.00 | 1.5e-01 | 5.1 | -5.2 | 2.4e-07 | -0.88 | 0.03 | 0.52 | FALSE |
| 6 | GTEx | Testis | COPRS | 0.31 | 0.26 | enet | 11 | 0.28 | 4.3e-13 | 5.2 | 5.2 | 1.7e-07 | 0.97 | 0.03 | 0.97 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Adenocarcinoma | LRRC37B | 0.02 | 0.02 | blup | 23 | 0.02 | 3.5e-03 | 5.1 | 5.1 | 3.1e-07 | 0.86 | 0.02 | 0.85 | FALSE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C17orf79 | 0.07 | 0.04 | lasso | 2 | 0.03 | 1.5e-04 | 5.2 | -5.2 | 1.5e-07 | -0.99 | 0.00 | 0.99 | TRUE |