[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) :

chr22:29,585,080-31,171,274

Best TWAS P=3.11e-16 · Best GWAS P=8.43e-17 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CTA-85E5.10 0.10 0.04 lasso 9 0.03 1.9e-03 7.42 -8.2 3.1e-16 -0.96 0.01 0.98 TRUE
2 GTEx Adipose Visceral Omentum MTMR3 0.22 0.11 enet 17 0.10 1.1e-05 -4.92 -5.1 2.8e-07 -0.19 1.00 0.00 TRUE
3 GTEx Breast Mammary Tissue MTMR3 0.33 0.26 lasso 6 0.29 2.0e-15 -4.94 -5.2 2.2e-07 -0.15 1.00 0.00 FALSE
4 GTEx Lung MTMR3 0.15 0.07 lasso 5 0.11 1.7e-08 -4.45 -5.2 2.6e-07 -0.17 1.00 0.00 FALSE
5 GTEx Lung CTA-85E5.10 0.09 0.01 enet 16 0.02 2.3e-02 -4.89 -6.0 2.2e-09 -0.52 0.06 0.55 TRUE
6 GTEx Muscle Skeletal MTMR3 0.07 0.04 lasso 3 0.03 5.5e-04 -4.94 -5.3 1.5e-07 -0.20 0.71 0.01 FALSE
7 GTEx Prostate MTMR3 0.62 0.29 lasso 14 0.24 9.3e-07 -4.94 -5.4 8.1e-08 -0.19 0.92 0.01 TRUE
8 GTEx Testis MTMR3 0.27 0.17 enet 13 0.26 8.9e-12 -3.55 -5.3 1.2e-07 -0.25 1.00 0.00 TRUE
9 The Cancer Genome Atlas Brain Lower Grade Glioma ASCC2 0.04 0.00 blup 48 0.01 1.1e-02 0.13 -5.9 4.6e-09 -0.57 0.01 0.62 TRUE
10 The Cancer Genome Atlas Thyroid Carcinoma HORMAD2 0.06 0.04 enet 10 0.07 5.7e-07 5.21 -5.5 3.9e-08 -0.42 0.99 0.01 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma MTMR3 0.21 0.08 blup 72 0.16 2.5e-15 5.38 -5.3 1.3e-07 -0.22 1.00 0.00 FALSE