[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ←

chr22:29,585,080-31,171,274

Best TWAS P=3.11e-16 · Best GWAS P=8.43e-17 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	CTA-85E5.10	0.10	0.04	lasso	9	0.03	1.9e-03	7.42	-8.2	3.1e-16	-0.96	0.01	0.98	TRUE
5	GTEx	Lung	CTA-85E5.10	0.09	0.01	enet	16	0.02	2.3e-02	-4.89	-6.0	2.2e-09	-0.52	0.06	0.55	TRUE
9	The Cancer Genome Atlas	Brain Lower Grade Glioma	ASCC2	0.04	0.00	blup	48	0.01	1.1e-02	0.13	-5.9	4.6e-09	-0.57	0.01	0.62	TRUE
7	GTEx	Prostate	MTMR3	0.62	0.29	lasso	14	0.24	9.3e-07	-4.94	-5.4	8.1e-08	-0.19	0.92	0.01	TRUE
8	GTEx	Testis	MTMR3	0.27	0.17	enet	13	0.26	8.9e-12	-3.55	-5.3	1.2e-07	-0.25	1.00	0.00	TRUE
2	GTEx	Adipose Visceral Omentum	MTMR3	0.22	0.11	enet	17	0.10	1.1e-05	-4.92	-5.1	2.8e-07	-0.19	1.00	0.00	TRUE
10	The Cancer Genome Atlas	Thyroid Carcinoma	HORMAD2	0.06	0.04	enet	10	0.07	5.7e-07	5.21	-5.5	3.9e-08	-0.42	0.99	0.01	FALSE
11	The Cancer Genome Atlas	Thyroid Carcinoma	MTMR3	0.21	0.08	blup	72	0.16	2.5e-15	5.38	-5.3	1.3e-07	-0.22	1.00	0.00	FALSE
6	GTEx	Muscle Skeletal	MTMR3	0.07	0.04	lasso	3	0.03	5.5e-04	-4.94	-5.3	1.5e-07	-0.20	0.71	0.01	FALSE
3	GTEx	Breast Mammary Tissue	MTMR3	0.33	0.26	lasso	6	0.29	2.0e-15	-4.94	-5.2	2.2e-07	-0.15	1.00	0.00	FALSE
4	GTEx	Lung	MTMR3	0.15	0.07	lasso	5	0.11	1.7e-08	-4.45	-5.2	2.6e-07	-0.17	1.00	0.00	FALSE