TWAS
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Traits
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Traits
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Forced expiratory volume in 1-second (FEV1)
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chr2:171,683,107-173,114,238
Best TWAS P=3.52e-08 · Best GWAS P=5.98e-07 conditioned to 0.00821
171.6M
171.8M
172M
172.2M
172.4M
172.6M
172.8M
173M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Coronary
CYBRD1
0.29
0.01
enet
44
0.11
2.0e-04
-2.6
5.5
3.5e-08
-0.49
0.02
0.28
TRUE
2
The Cancer Genome Atlas
Thyroid Carcinoma
CYBRD1
0.10
0.06
lasso
4
0.06
6.2e-07
-5.0
5.3
1.0e-07
-0.88
0.00
0.99
FALSE