Best TWAS P=3.64e-09 · Best GWAS P=9.98e-08 conditioned to 0.414
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Nucleus accumbens basal ganglia | AC073834.3 | 0.16 | 0.01 | enet | 33 | 0.05 | 2.1e-02 | -4.9 | -5.5 | 4.0e-08 | 0.69 | 0.05 | 0.88 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Male) | AC073834.3 | 0.22 | 0.13 | enet | 18 | 0.07 | 8.7e-03 | -3.7 | -5.1 | 2.9e-07 | 0.88 | 0.06 | 0.79 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | AC073834.3 | 0.13 | 0.16 | lasso | 2 | 0.16 | 6.7e-12 | -5.0 | -5.2 | 1.8e-07 | 0.75 | 0.04 | 0.96 | FALSE |
| 4 | GTEx | Pituitary | AC073834.3 | 0.18 | 0.18 | lasso | 7 | 0.12 | 7.2e-04 | -5.2 | -5.5 | 3.8e-08 | 0.97 | 0.04 | 0.86 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | AC073834.3 | 0.07 | 0.07 | lasso | 3 | 0.06 | 9.5e-06 | -5.0 | -5.1 | 2.9e-07 | 0.73 | 0.05 | 0.93 | FALSE |
| 6 | GTEx | Spleen | AC073834.3 | 0.17 | 0.08 | enet | 22 | 0.08 | 3.6e-03 | -4.9 | -5.9 | 3.6e-09 | 0.82 | 0.05 | 0.82 | TRUE |