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Forced expiratory volume in 1-second (FEV1)
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chr9:97,520,168-99,734,369
Best TWAS P=1.61e-08 · Best GWAS P=3.28e-10 conditioned to 0.0168
97.5M
98M
98.5M
99M
99.5M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
GTEx
Liver
PTCH1
0.25
0.06
enet
11
0.03
4.9e-02
6.1
5.6
1.6e-08
0.91
0.01
0.92
TRUE
3
GTEx
Esophagus Muscularis
ERCC6L2
0.15
0.10
lasso
6
0.08
8.8e-06
4.8
5.4
7.1e-08
-0.01
0.80
0.09
TRUE
5
GTEx
Nerve Tibial
HSD17B3
0.14
0.00
enet
20
0.00
2.4e-01
4.4
5.1
2.8e-07
0.04
0.04
0.63
TRUE
2
GTEx
Breast Mammary Tissue
ERCC6L2
0.17
0.02
lasso
4
0.03
1.2e-02
4.7
5.4
8.8e-08
-0.03
0.27
0.05
FALSE
1
GTEx
Artery Tibial
ERCC6L2
0.22
0.18
enet
39
0.18
5.2e-14
4.7
5.2
2.1e-07
-0.05
0.91
0.09
FALSE