[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr9:138,403,706-139,836,362

Best TWAS P=2.94e-15 · Best GWAS P=2.38e-12 conditioned to 0.912

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Cells Transformed fibroblasts	QSOX2	0.40	0.25	enet	11	0.30	5.2e-23	-7.0	7.9	2.9e-15	-0.89	0.00	1.00	TRUE
11	The Cancer Genome Atlas	Prostate Adenocarcinoma	QSOX2	0.08	0.07	lasso	4	0.08	1.2e-08	-7.0	7.9	3.9e-15	-0.92	0.00	1.00	FALSE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	QSOX2	0.04	0.01	enet	4	0.03	3.6e-04	-7.0	7.7	1.4e-14	-0.87	0.00	0.98	FALSE
9	The Cancer Genome Atlas	Brain Lower Grade Glioma	QSOX2	0.06	0.05	lasso	2	0.05	2.5e-06	6.4	7.6	2.1e-14	-0.72	0.01	0.97	FALSE
1	CommonMind	Brain Pre-frontal Cortex	QSOX2	0.18	0.11	lasso	4	0.10	1.0e-12	6.4	7.6	3.6e-14	-0.71	0.08	0.92	FALSE
10	The Cancer Genome Atlas	Lung Adenocarcinoma	QSOX2	0.05	0.05	enet	4	0.05	2.7e-06	-7.0	7.4	1.4e-13	-0.94	0.00	1.00	FALSE
5	The Cancer Genome Atlas	Breast Invasive Carcinoma	QSOX2	0.05	0.03	blup	32	0.03	2.8e-07	-7.0	7.4	1.8e-13	-0.76	0.00	1.00	FALSE
12	The Cancer Genome Atlas	Skin Cutaneous Melanoma	QSOX2	0.28	0.01	enet	4	0.05	1.6e-02	-7.0	7.3	2.2e-13	-0.88	0.00	0.65	FALSE
8	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	QSOX2	0.10	0.11	lasso	2	0.10	1.6e-06	-7.0	7.1	1.2e-12	-1.00	0.00	1.00	FALSE
6	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	QSOX2	0.10	0.03	enet	6	0.06	3.4e-07	5.7	7.0	1.9e-12	-0.74	0.01	0.99	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	QSOX2	0.06	0.01	blup	32	0.05	1.6e-05	5.7	6.6	4.0e-11	-0.62	0.01	0.85	FALSE
3	GTEx	Esophagus Muscularis	QSOX2	0.16	0.07	lasso	4	0.06	1.4e-04	6.3	5.6	2.5e-08	-0.35	0.15	0.73	FALSE
4	GTEx	Nerve Tibial	QSOX2	0.22	0.12	enet	12	0.17	4.6e-12	5.5	5.4	8.6e-08	-0.43	0.70	0.30	FALSE