[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr9:138,403,706-139,836,362

Best TWAS P=2.94e-15 · Best GWAS P=2.38e-12 conditioned to 0.912

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex QSOX2 0.18 0.11 lasso 4 0.10 1.0e-12 6.4 7.6 3.6e-14 -0.71 0.08 0.92 FALSE
2 GTEx Cells Transformed fibroblasts QSOX2 0.40 0.25 enet 11 0.30 5.2e-23 -7.0 7.9 2.9e-15 -0.89 0.00 1.00 TRUE
3 GTEx Esophagus Muscularis QSOX2 0.16 0.07 lasso 4 0.06 1.4e-04 6.3 5.6 2.5e-08 -0.35 0.15 0.73 FALSE
4 GTEx Nerve Tibial QSOX2 0.22 0.12 enet 12 0.17 4.6e-12 5.5 5.4 8.6e-08 -0.43 0.70 0.30 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma QSOX2 0.05 0.03 blup 32 0.03 2.8e-07 -7.0 7.4 1.8e-13 -0.76 0.00 1.00 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma QSOX2 0.10 0.03 enet 6 0.06 3.4e-07 5.7 7.0 1.9e-12 -0.74 0.01 0.99 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma QSOX2 0.04 0.01 enet 4 0.03 3.6e-04 -7.0 7.7 1.4e-14 -0.87 0.00 0.98 FALSE
8 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma QSOX2 0.10 0.11 lasso 2 0.10 1.6e-06 -7.0 7.1 1.2e-12 -1.00 0.00 1.00 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma QSOX2 0.06 0.05 lasso 2 0.05 2.5e-06 6.4 7.6 2.1e-14 -0.72 0.01 0.97 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma QSOX2 0.05 0.05 enet 4 0.05 2.7e-06 -7.0 7.4 1.4e-13 -0.94 0.00 1.00 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma QSOX2 0.08 0.07 lasso 4 0.08 1.2e-08 -7.0 7.9 3.9e-15 -0.92 0.00 1.00 FALSE
12 The Cancer Genome Atlas Skin Cutaneous Melanoma QSOX2 0.28 0.01 enet 4 0.05 1.6e-02 -7.0 7.3 2.2e-13 -0.88 0.00 0.65 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma QSOX2 0.06 0.01 blup 32 0.05 1.6e-05 5.7 6.6 4.0e-11 -0.62 0.01 0.85 FALSE