[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) :

chr12:27,616,589-29,042,392

Best TWAS P=2.27e-10 · Best GWAS P=2.02e-09 conditioned to 0.38

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-967K21.1 0.08 0.02 lasso 8 0.01 2.1e-02 -5.9 -6.3 2.3e-10 0.88 0.02 0.96 TRUE
2 GTEx Adrenal Gland RP11-967K21.1 0.22 0.02 lasso 4 0.02 6.5e-02 -5.6 -5.5 3.2e-08 0.83 0.04 0.66 FALSE
3 GTEx Artery Coronary RP11-967K21.1 0.18 0.12 lasso 7 0.07 1.8e-03 -5.6 -5.9 4.3e-09 0.95 0.04 0.94 FALSE
4 GTEx Artery Tibial RP11-967K21.1 0.09 0.10 lasso 11 0.07 2.4e-06 -6.0 -6.0 2.1e-09 0.97 0.01 0.99 FALSE
5 GTEx Colon Transverse RP11-967K21.1 0.12 0.07 lasso 8 0.05 1.6e-03 -6.0 -5.9 3.5e-09 0.94 0.02 0.97 FALSE
6 GTEx Esophagus Muscularis RP11-967K21.1 0.07 0.06 lasso 5 0.04 2.2e-03 -6.0 -5.9 3.9e-09 0.95 0.02 0.95 FALSE
7 GTEx Thyroid RP11-967K21.1 0.05 0.00 enet 7 0.00 2.8e-01 -3.2 -5.1 2.6e-07 0.66 0.05 0.66 FALSE