Best TWAS P=2.27e-10 · Best GWAS P=2.02e-09 conditioned to 0.38
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RP11-967K21.1 | 0.08 | 0.02 | lasso | 8 | 0.01 | 2.1e-02 | -5.9 | -6.3 | 2.3e-10 | 0.88 | 0.02 | 0.96 | TRUE |
| 4 | GTEx | Artery Tibial | RP11-967K21.1 | 0.09 | 0.10 | lasso | 11 | 0.07 | 2.4e-06 | -6.0 | -6.0 | 2.1e-09 | 0.97 | 0.01 | 0.99 | FALSE |
| 5 | GTEx | Colon Transverse | RP11-967K21.1 | 0.12 | 0.07 | lasso | 8 | 0.05 | 1.6e-03 | -6.0 | -5.9 | 3.5e-09 | 0.94 | 0.02 | 0.97 | FALSE |
| 6 | GTEx | Esophagus Muscularis | RP11-967K21.1 | 0.07 | 0.06 | lasso | 5 | 0.04 | 2.2e-03 | -6.0 | -5.9 | 3.9e-09 | 0.95 | 0.02 | 0.95 | FALSE |
| 3 | GTEx | Artery Coronary | RP11-967K21.1 | 0.18 | 0.12 | lasso | 7 | 0.07 | 1.8e-03 | -5.6 | -5.9 | 4.3e-09 | 0.95 | 0.04 | 0.94 | FALSE |
| 2 | GTEx | Adrenal Gland | RP11-967K21.1 | 0.22 | 0.02 | lasso | 4 | 0.02 | 6.5e-02 | -5.6 | -5.5 | 3.2e-08 | 0.83 | 0.04 | 0.66 | FALSE |
| 7 | GTEx | Thyroid | RP11-967K21.1 | 0.05 | 0.00 | enet | 7 | 0.00 | 2.8e-01 | -3.2 | -5.1 | 2.6e-07 | 0.66 | 0.05 | 0.66 | FALSE |