[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr12:30,084,002-31,526,510

Best TWAS P=5.63e-12 · Best GWAS P=1.51e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous IPO8 0.13 0.09 lasso 6 0.12 2.7e-10 4.5 -6.1 1.2e-09 0.79 0.30 0.70 FALSE
2 GTEx Artery Tibial IPO8 0.17 0.14 lasso 4 0.14 4.5e-11 4.4 -5.2 2.2e-07 0.67 0.65 0.35 FALSE
3 GTEx Cells EBV-transformed lymphocytes IPO8 0.22 0.14 lasso 4 0.14 2.5e-05 -7.0 -6.2 4.6e-10 0.88 0.02 0.97 FALSE
4 GTEx Esophagus Muscularis IPO8 0.24 0.19 lasso 6 0.18 5.7e-11 4.8 -5.2 2.6e-07 0.60 0.97 0.03 FALSE
5 GTEx Lung IPO8 0.07 0.06 lasso 5 0.07 7.5e-06 4.5 -6.4 1.7e-10 0.77 0.10 0.90 FALSE
6 GTEx Nerve Tibial IPO8 0.21 0.16 lasso 6 0.15 1.3e-10 -6.9 -6.9 5.6e-12 1.00 0.02 0.98 TRUE
7 GTEx Skin Sun Exposed Lower leg IPO8 0.23 0.08 lasso 10 0.13 1.1e-10 -7.0 -6.7 2.5e-11 0.87 0.02 0.98 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma IPO8 0.05 0.03 lasso 3 0.03 1.3e-06 4.5 -5.3 1.0e-07 0.64 0.72 0.28 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma IPO8 0.06 0.04 blup 58 0.04 1.5e-05 4.7 -5.7 1.4e-08 0.74 0.35 0.63 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IPO8 0.04 0.03 blup 58 0.03 9.7e-05 4.5 -5.7 1.2e-08 0.72 0.31 0.52 FALSE