[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr13:49,557,805-51,390,447

Best TWAS P=1.77e-15 · Best GWAS P=3.35e-15 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TRIM13 0.15 0.04 lasso 5 0.12 1.1e-14 7.8 -6.2 5.2e-10 -0.81 0.01 0.99 FALSE
2 GTEx Brain Cerebellum EBPL 0.50 0.30 enet 23 0.36 1.8e-11 7.5 -5.3 1.1e-07 -0.24 0.19 0.78 FALSE
3 GTEx Esophagus Gastroesophageal Junction EBPL 0.27 0.24 enet 14 0.26 4.6e-10 5.9 -6.0 2.0e-09 -0.29 0.90 0.09 FALSE
4 GTEx Nerve Tibial DLEU2 0.11 0.05 lasso 3 0.02 7.8e-03 7.9 8.0 1.8e-15 0.98 0.01 0.98 TRUE
5 GTEx Pancreas EBPL 0.18 0.10 enet 5 0.09 1.6e-04 7.5 -5.6 2.1e-08 -0.22 0.12 0.71 TRUE
6 GTEx Pituitary EBPL 0.44 0.32 enet 29 0.37 3.1e-10 6.0 -5.7 1.3e-08 -0.36 0.62 0.33 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic EBPL 0.34 0.26 enet 12 0.30 4.0e-17 6.0 -6.1 9.0e-10 -0.25 0.93 0.07 FALSE
8 GTEx Skin Sun Exposed Lower leg EBPL 0.28 0.21 lasso 5 0.20 2.5e-16 6.0 -6.3 2.5e-10 -0.31 1.00 0.00 FALSE
9 GTEx Testis EBPL 0.33 0.17 lasso 6 0.24 8.4e-11 6.0 -7.4 1.7e-13 -0.32 0.58 0.42 TRUE
10 GTEx Thyroid EBPL 0.36 0.14 enet 33 0.30 5.1e-23 5.9 -5.1 2.9e-07 -0.31 0.48 0.52 TRUE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DLEU2 0.03 0.01 blup 61 0.02 2.4e-03 7.8 7.4 1.7e-13 0.91 0.01 0.96 TRUE
12 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma EBPL 0.28 0.18 blup 59 0.19 4.3e-08 6.0 -5.2 2.0e-07 -0.23 0.01 0.98 TRUE
13 The Cancer Genome Atlas Prostate Adenocarcinoma EBPL 0.08 0.01 blup 59 0.04 6.4e-05 6.0 -6.0 1.6e-09 -0.27 0.01 0.89 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma TRIM13 0.04 0.00 blup 26 0.02 8.5e-03 7.9 -5.3 1.2e-07 -0.65 0.00 0.46 FALSE