[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr13:49,557,805-51,390,447

Best TWAS P=1.77e-15 · Best GWAS P=3.35e-15 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Nerve Tibial	DLEU2	0.11	0.05	lasso	3	0.02	7.8e-03	7.9	8.0	1.8e-15	0.98	0.01	0.98	TRUE
9	GTEx	Testis	EBPL	0.33	0.17	lasso	6	0.24	8.4e-11	6.0	-7.4	1.7e-13	-0.32	0.58	0.42	TRUE
11	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DLEU2	0.03	0.01	blup	61	0.02	2.4e-03	7.8	7.4	1.7e-13	0.91	0.01	0.96	TRUE
5	GTEx	Pancreas	EBPL	0.18	0.10	enet	5	0.09	1.6e-04	7.5	-5.6	2.1e-08	-0.22	0.12	0.71	TRUE
12	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	EBPL	0.28	0.18	blup	59	0.19	4.3e-08	6.0	-5.2	2.0e-07	-0.23	0.01	0.98	TRUE
10	GTEx	Thyroid	EBPL	0.36	0.14	enet	33	0.30	5.1e-23	5.9	-5.1	2.9e-07	-0.31	0.48	0.52	TRUE
8	GTEx	Skin Sun Exposed Lower leg	EBPL	0.28	0.21	lasso	5	0.20	2.5e-16	6.0	-6.3	2.5e-10	-0.31	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	TRIM13	0.15	0.04	lasso	5	0.12	1.1e-14	7.8	-6.2	5.2e-10	-0.81	0.01	0.99	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	EBPL	0.34	0.26	enet	12	0.30	4.0e-17	6.0	-6.1	9.0e-10	-0.25	0.93	0.07	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	EBPL	0.08	0.01	blup	59	0.04	6.4e-05	6.0	-6.0	1.6e-09	-0.27	0.01	0.89	FALSE
3	GTEx	Esophagus Gastroesophageal Junction	EBPL	0.27	0.24	enet	14	0.26	4.6e-10	5.9	-6.0	2.0e-09	-0.29	0.90	0.09	FALSE
6	GTEx	Pituitary	EBPL	0.44	0.32	enet	29	0.37	3.1e-10	6.0	-5.7	1.3e-08	-0.36	0.62	0.33	FALSE
2	GTEx	Brain Cerebellum	EBPL	0.50	0.30	enet	23	0.36	1.8e-11	7.5	-5.3	1.1e-07	-0.24	0.19	0.78	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	TRIM13	0.04	0.00	blup	26	0.02	8.5e-03	7.9	-5.3	1.2e-07	-0.65	0.00	0.46	FALSE