[Hub]/) : Traits : Peak expiratory flow (PEF) : ← →

chr4:17,104,059-18,507,692

Best TWAS P=9.33e-12 · Best GWAS P=5e-11 conditioned to 0.0301

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta DCAF16 0.10 0.01 enet 6 0.02 4.7e-02 -6.2 6.6 4.0e-11 -0.81 0.05 0.78 FALSE
2 GTEx Breast Mammary Tissue DCAF16 0.12 0.08 lasso 4 0.10 6.4e-06 4.1 5.3 1.1e-07 -0.52 0.10 0.76 FALSE
3 GTEx Breast Mammary Tissue (Male) DCAF16 0.24 0.03 enet 18 -0.01 4.4e-01 -6.3 6.8 9.3e-12 -0.76 0.03 0.66 TRUE
4 GTEx Spleen DCAF16 0.35 0.02 lasso 5 0.11 8.5e-04 3.9 5.9 4.7e-09 -0.66 0.05 0.61 FALSE
5 GTEx Thyroid DCAF16 0.11 0.02 lasso 5 0.03 2.3e-03 3.9 5.7 1.2e-08 -0.54 0.20 0.65 FALSE
6 ROSMAP Brain Pre-frontal Cortex DCAF16 0.04 0.02 bslmm 379 0.01 3.9e-02 -6.3 5.8 6.2e-09 -0.83 0.03 0.89 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma NCAPG 0.08 0.04 blup 34 0.09 1.1e-05 -6.3 -5.5 4.7e-08 0.84 0.01 0.98 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NCAPG 0.14 0.07 lasso 3 0.07 5.2e-08 -6.3 -6.2 7.7e-10 0.84 0.01 0.99 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma DCAF16 0.09 0.02 lasso 3 0.04 5.2e-05 4.1 6.3 2.3e-10 -0.64 0.04 0.91 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma NCAPG 0.02 0.03 lasso 1 0.02 9.0e-04 -6.3 -6.3 4.0e-10 0.88 0.01 0.85 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma DCAF16 0.04 0.04 blup 31 0.04 2.2e-05 3.9 5.6 1.9e-08 -0.58 0.24 0.31 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma NCAPG 0.02 0.02 blup 34 0.02 3.4e-03 -6.0 -5.5 4.0e-08 0.76 0.02 0.69 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma DCAF16 0.07 0.04 blup 31 0.07 4.9e-07 4.1 6.3 2.4e-10 -0.65 0.18 0.73 FALSE