Best TWAS P=7.21e-08 · Best GWAS P=3.51e-07 conditioned to 0.0764
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Not Sun Exposed Suprapubic | TMEM194B | 0.16 | 0.04 | enet | 22 | 0.09 | 1.8e-05 | -3.5 | -5.2 | 2.6e-07 | 0.78 | 0.04 | 0.94 | FALSE |
2 | GTEx | Whole Blood | TMEM194B | 0.04 | 0.00 | lasso | 2 | 0.01 | 5.7e-02 | 5.1 | -5.2 | 1.7e-07 | 0.62 | 0.01 | 0.93 | FALSE |
3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | TMEM194B | 0.09 | 0.02 | blup | 41 | 0.04 | 6.0e-03 | 4.9 | -5.4 | 7.2e-08 | 0.72 | 0.01 | 0.70 | TRUE |