Best TWAS P=2.65e-08 · Best GWAS P=6.48e-09 conditioned to 0.00975
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | FAM172A | 0.06 | 0.07 | lasso | 1 | 0.06 | 9.6e-08 | 5.1 | -5.1 | 2.8e-07 | -0.66 | 0.26 | 0.74 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | FAM172A | 0.05 | 0.04 | lasso | 3 | 0.06 | 3.0e-07 | 5.4 | -5.6 | 2.6e-08 | -0.72 | 0.12 | 0.88 | TRUE |