Best TWAS P=3.66e-09 · Best GWAS P=8.3e-10 conditioned to 0.000969
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | NPM3 | 0.13 | 0.15 | lasso | 3 | 0.13 | 2.5e-06 | -5.4 | 5.4 | 6.9e-08 | 0.47 | 0.26 | 0.62 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | NPM3 | 0.02 | 0.03 | lasso | 3 | 0.02 | 9.2e-04 | -5.4 | 5.9 | 3.7e-09 | 0.59 | 0.01 | 0.72 | TRUE |
| 3 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | C10orf76 | 0.19 | 0.20 | lasso | 1 | 0.18 | 4.6e-07 | -5.4 | -5.4 | 8.2e-08 | -0.46 | 0.32 | 0.59 | FALSE |