[Hub]/) : Traits : Diastolic blood pressure, automated reading : ← →

chr2:189,930,854-192,525,536

Best TWAS P=5.01e-12 · Best GWAS P=1.11e-07 conditioned to 0.645

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum GLS 0.13 0.08 lasso 4 0.07 1.5e-04 -4.7 -5.4 8.4e-08 0.31 0.17 0.71 TRUE
2 GTEx Artery Coronary MFSD6 0.23 0.07 lasso 7 0.05 6.3e-03 -5.2 -5.2 2.2e-07 0.94 0.04 0.72 FALSE
3 GTEx Artery Tibial AC005540.3 0.10 0.09 lasso 4 0.08 7.4e-07 -4.6 5.3 1.5e-07 -0.25 0.24 0.71 FALSE
4 GTEx Brain Cerebellar Hemisphere MFSD6 0.14 0.20 lasso 4 0.13 2.8e-04 -5.3 -5.2 2.5e-07 0.97 0.02 0.93 FALSE
5 GTEx Brain Cerebellum RP11-455J20.3 0.49 0.17 enet 33 0.29 3.3e-09 3.8 -5.3 1.4e-07 0.02 0.08 0.60 FALSE
6 GTEx Brain Hypothalamus MSTN 0.24 -0.01 enet 18 0.09 4.8e-03 -2.7 -6.9 5.0e-12 0.47 0.04 0.59 TRUE
7 GTEx Small Intestine Terminal Ileum HIBCH 0.20 0.07 enet 25 0.07 1.1e-02 -3.2 5.3 1.0e-07 -0.54 0.18 0.38 FALSE
8 GTEx Thyroid AC005540.3 0.09 0.07 enet 5 0.04 2.5e-04 -4.6 5.1 3.1e-07 -0.21 0.20 0.72 FALSE
9 YFS Blood GLS 0.08 0.08 lasso 8 0.08 4.7e-26 -4.6 -5.2 2.4e-07 0.22 0.22 0.77 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma GLS 0.02 0.01 enet 6 0.02 9.6e-05 4.4 -5.1 2.7e-07 0.24 0.03 0.84 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TMEM194B 0.06 0.06 lasso 6 0.06 2.4e-07 -5.2 -5.2 2.5e-07 0.52 0.01 0.99 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma TMEM194B 0.03 0.04 lasso 2 0.04 4.5e-05 -5.2 -5.2 2.0e-07 0.97 0.01 0.96 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma MFSD6 0.06 0.05 enet 6 0.06 3.9e-06 -4.6 -5.1 2.8e-07 0.91 0.01 0.98 FALSE