Hub : Traits :

Diastolic blood pressure, automated reading

2121 significantly associated models · 448 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 7686056 9571422 3 1 4.8e-15 8.8e-13 3.5e-01 98 RERE
2 1 11032827 12600396 5 10 7.6e-35 3.6e-32 NaN NaN C1orf167 CLCN6 MTHFR
3 1 37730550 39147240 1 1 4.0e-08 1.4e-07 1.5e-02 78 SF3A3
4 1 41253185 41957439 1 1 1.8e-07 2.0e-07 3.0e-02 83 SCMH1
5 1 43073464 44618031 10 1 1.7e-11 9.3e-11 3.6e-02 90 HYI
6 1 112312154 114366434 8 2 1.7e-13 1.2e-13 4.5e-08 46 SLC16A1 WNT2B
7 1 183961643 185416670 1 1 3.7e-08 1.5e-06 6.3e-01 99 EDEM3
8 1 201158976 202607593 3 1 1.0e-09 7.0e-13 3.3e-09 32 LMOD1
9 1 230142626 231548480 1 1 3.6e-16 8.9e-13 4.9e-01 99 AGT
10 1 242590540 244359621 3 1 3.8e-22 3.8e-22 1.0e+00 100 RP11-261C10.5
11 2 73169500 74565186 2 1 3.5e-08 1.2e-07 3.4e-01 97 NAT8
12 2 95420294 98024837 16 1 1.5e-13 3.0e-13 1.0e+00 100 ADRA2B
13 2 112143413 113572357 1 1 1.9e-08 3.9e-09 4.9e-04 65 TMEM87B
14 2 134513621 137435625 6 1 5.2e-09 4.5e-08 9.2e-01 100 LOC100129961
15 2 147905651 149475737 3 1 6.7e-08 5.8e-08 1.0e+00 100 ACVR2A
16 2 158332890 160006143 2 1 2.4e-10 8.2e-12 9.9e-03 86 CCDC148
17 2 171867383 173555880 3 1 5.8e-09 5.3e-09 1.0e+00 100 DYNC1I2
18 2 182305254 184084221 1 1 2.3e-11 1.7e-17 2.1e-08 57 PDE1A
19 2 189930854 192525536 7 2 5.0e-12 1.1e-07 6.5e-01 99 GLS MSTN
20 3 40537829 42967174 3 2 2.5e-23 6.9e-21 1.0e+00 100 CTNNB1 ULK4
21 3 47204518 50833360 23 2 3.3e-14 3.3e-11 7.0e-01 100 NME6 RNF123
22 3 57294295 58854266 2 1 3.7e-12 1.7e-11 2.2e-01 97 FLNB
23 3 107181540 108633112 1 1 2.8e-07 1.7e-07 1.0e+00 100 IFT57
24 3 121346656 122821385 4 1 3.5e-08 9.3e-09 5.7e-05 51 CSTA
25 3 123792729 125314016 1 1 2.4e-10 2.4e-09 4.9e-01 99 ITGB5
26 3 133088362 134770520 2 2 1.4e-07 4.2e-08 3.2e-01 97 RPL39P5 RYK
27 3 157125828 159106064 3 1 1.2e-10 1.6e-09 7.4e-01 100 RSRC1
28 4 17104059 18507692 2 1 8.4e-10 4.0e-08 1.1e-01 92 DCAF16
29 4 80488345 82578407 2 1 2.5e-10 2.3e-34 7.5e-26 26 C4orf22
30 4 101698032 102513322 1 1 3.0e-09 6.5e-10 1.4e-02 84 PPP3CA
31 4 102868793 104374596 1 1 6.4e-08 1.6e-19 4.8e-21 -9 MANBA
32 4 119605671 120922444 1 1 2.2e-07 2.2e-08 4.9e-03 75 C4orf3
33 5 60903201 62529686 3 1 4.9e-12 2.3e-11 1.0e+00 100 IPO11
34 5 87104604 88677293 1 1 1.3e-08 6.3e-09 1.9e-01 95 LINC00461
35 5 95519506 97065386 2 1 1.7e-09 9.6e-09 6.9e-01 100 ERAP2
36 5 122045488 123649166 3 1 3.9e-13 2.9e-13 1.4e-03 81 KRT8P33
37 5 172620700 174088123 1 1 4.7e-17 1.5e-17 1.0e+00 100 CPEB4
38 6 25285943 26689223 1 1 1.9e-10 2.6e-15 4.2e-12 23 U91328.21
39 6 51230788 52198802 1 1 9.0e-09 2.5e-13 5.9e-06 62 PKHD1
40 6 78880271 81763771 4 3 2.8e-12 1.7e-12 8.7e-02 94 BCKDHB IRAK1BP1
41 6 108994161 110396540 1 1 2.2e-07 2.1e-08 1.3e-03 67 CD164
42 6 118089396 119728438 2 1 3.7e-08 3.8e-08 2.4e-01 95 CEP85L
43 6 146826657 148410391 2 1 4.3e-09 4.0e-08 2.5e-01 96 STXBP5
44 7 6502367 7988091 1 1 3.8e-09 2.6e-08 4.8e-01 98 C1GALT1
45 7 27049529 27533292 1 1 2.0e-07 4.0e-09 2.5e-03 74 EVX1
46 7 45709404 46210616 1 1 1.3e-07 8.6e-13 1.3e-06 54 IGFBP3
47 7 73017005 75842792 9 2 4.8e-11 8.4e-08 3.3e-01 97 NCF1 STAG3L1
48 7 89096541 90699073 4 1 4.9e-11 1.9e-10 4.8e-01 99 STEAP1
49 7 98915958 101185166 14 8 1.7e-14 1.3e-12 1.0e+00 100 ACHE GIGYF1 STAG3 TRIP6 ZKSCAN1
50 7 149563894 150920503 2 1 1.3e-10 1.5e-11 8.0e-09 27 GIMAP7
51 8 8092025 13120332 37 2 2.7e-19 4.1e-19 9.0e-03 91 MSRA NEIL2
52 8 22687572 24094711 1 1 4.0e-08 8.0e-08 2.2e-01 95 SLC25A37
53 8 95139766 96825195 4 1 5.1e-10 3.9e-10 2.9e-02 88 C8orf38
54 8 119737284 121136001 1 1 1.0e-17 6.1e-18 1.0e+00 100 NOV
55 9 135883620 136399075 1 1 1.9e-10 2.2e-10 3.8e-03 79 ABO
56 9 138875850 140268976 1 1 3.1e-07 1.7e-10 6.4e-11 -5 AGPAT2
57 10 18221643 19637020 2 2 6.0e-11 3.2e-17 2.4e-14 18 CACNB2 NSUN6
58 10 21123825 22724472 1 1 2.9e-08 5.5e-08 6.3e-02 88 MLLT10
59 10 63856856 66034105 5 3 1.8e-21 7.4e-17 2.0e-01 98 NRBF2 REEP3 RP11-436D10.3
60 10 95379543 96818402 1 1 5.2e-10 1.0e-13 1.3e-06 57 NOC3L
61 10 103572925 105850787 6 1 2.4e-17 9.5e-17 4.3e-02 94 NT5C2
62 10 114740745 116183647 3 3 2.6e-17 7.0e-22 8.3e-09 64 ADRB1 C10orf118 CASP7
63 11 1242690 2640824 3 3 5.1e-12 2.4e-11 NaN NaN LSP1 TNNI2 TNNT3
64 11 9003306 11027552 2 2 1.1e-12 5.5e-15 2.2e-02 91 ADM SWAP70
65 11 12611333 14105497 1 1 9.5e-08 5.5e-10 5.4e-04 69 ARNTL
66 11 46570859 48783497 10 1 1.4e-10 4.7e-10 8.0e-03 82 ACP2
67 11 56774260 58178587 1 1 5.4e-08 1.2e-06 4.7e-02 83 MED19
68 11 64721908 66333072 6 8 7.9e-13 4.8e-11 NaN NaN CTSW FIBP MAP3K11 SIPA1 SNX32
69 11 76673980 78578480 8 3 1.1e-08 7.4e-08 1.0e+00 100 C11orf67 INTS4 RP11-91P24.7
70 11 94199272 95663017 1 1 3.7e-10 3.2e-11 1.9e-02 88 SESN3
71 11 99859184 101559718 2 1 2.1e-36 4.8e-35 1.0e+00 100 ARHGAP42
72 11 106485489 107882823 1 1 8.2e-08 6.9e-10 4.1e-04 67 RP11-819C21.1
73 11 129575976 130992111 1 1 5.4e-16 3.5e-16 4.7e-02 94 ADAMTS8
74 12 49780778 51912062 7 1 1.9e-15 1.8e-15 1.0e+00 100 CERS5
75 12 52742148 54146451 1 1 3.8e-08 1.4e-08 1.1e-01 92 TENC1
76 12 89286081 90799212 2 2 6.6e-09 8.9e-16 1.1e-06 63 ATP2B1 LOC338758
77 12 109973273 113517494 22 12 7.0e-41 1.7e-54 NaN NaN ADAM1A ALDH2 BRAP ERP29 GPN3 NAA25 PPTC7 SH2B3 VPS29
78 12 120498862 120999127 1 1 2.2e-09 1.8e-06 5.0e-01 98 SIRT4
79 12 122625212 124715313 13 7 1.8e-14 5.9e-13 1.0e+00 100 ABCB9 MPHOSPH9 PITPNM2 RP11-282O18.3 SETD8
80 13 114259570 114762917 1 1 1.5e-07 5.6e-08 1.9e-02 81 FAM70B
81 14 22722491 24125886 1 1 7.4e-09 7.4e-07 2.0e-06 8 HAUS4
82 14 55273730 56741515 1 1 2.6e-07 1.9e-08 4.2e-03 74 KTN1-AS1
83 15 39530508 43198430 20 8 3.7e-14 8.9e-13 1.0e+00 100 CHP1 EHD4 EIF2AK4 EXD1 INO80 JMJD7-PLA2G4B RP11-23P13.4 RPAP1
84 15 48352252 49794848 1 1 1.3e-11 1.9e-08 2.8e-01 96 CEP152
85 15 70697945 72771648 1 1 3.2e-08 3.7e-09 3.7e-02 88 THSD4
86 15 73933444 76108550 13 1 3.1e-28 1.0e-27 7.3e-03 94 MPI
87 15 77888924 79802863 2 1 2.6e-12 5.5e-12 3.7e-02 91 ADAMTS7
88 15 80743350 81292020 1 1 2.9e-07 2.4e-10 1.7e-04 65 FAM108C1
89 15 90712555 92135418 3 2 4.0e-28 4.8e-24 9.3e-01 100 FES FURIN
90 16 1381714 2713729 1 1 7.8e-08 1.8e-08 8.3e-02 90 SLC9A3R2
91 16 3301360 4696654 1 1 2.8e-07 3.0e-08 2.7e-02 84 RP11-462G12.1
92 16 24614505 25167985 1 1 2.3e-07 2.5e-07 3.0e-01 96 SLC5A11
93 16 29850705 31860399 18 2 4.4e-13 4.0e-10 4.1e-01 98 C16orf93 PRSS53
94 16 55526487 57089130 1 1 1.8e-07 8.3e-07 1.5e-01 91 GNAO1
95 16 68523336 70063989 2 1 1.7e-09 4.6e-08 8.3e-02 90 SNTB2
96 16 81230341 84527021 2 2 1.1e-11 8.3e-13 5.9e-03 85 CDH13 CMIP
97 17 1508522 2923933 3 1 4.9e-11 1.6e-09 1.0e+00 100 SRR
98 17 3208350 5323989 4 2 7.2e-09 7.1e-10 3.0e-04 66 ANKFY1 ARRB2
99 17 6397773 8484683 12 3 1.5e-10 3.7e-10 1.0e+00 100 C17orf81 CYB5D1 EIF5A
100 17 14714000 16109675 1 1 2.6e-07 1.0e-07 3.4e-02 84 AC005517.3
101 17 42413481 43570226 5 1 1.6e-12 1.4e-11 2.7e-01 97 NMT1
102 17 46888301 48347817 2 1 8.2e-10 4.0e-10 2.0e-05 54 RP5-1029K10.2
103 17 56487887 57889985 1 1 2.9e-07 1.5e-07 5.9e-02 87 AC099850.1
104 17 76087754 77462467 1 1 5.8e-08 2.1e-08 1.0e+00 100 USP36
105 19 16914952 17430915 1 1 2.5e-07 3.3e-08 4.0e-02 86 HAUS8
106 19 21206463 22643745 1 1 2.1e-07 3.3e-06 9.3e-02 87 ZNF100
107 19 29606361 31013761 1 1 3.6e-19 6.3e-19 6.5e-02 96 CCNE1
108 20 9925555 11347455 1 1 4.9e-10 2.6e-22 2.5e-19 14 JAG1
109 20 18506005 20398583 1 1 4.0e-09 1.3e-09 1.1e-01 93 SLC24A3
110 20 29833609 31312916 2 1 1.3e-10 2.1e-07 2.6e-01 95 C20orf160
111 20 46551079 48140682 1 1 2.4e-09 3.2e-11 5.6e-13 -18 PREX1
112 20 56858751 58262841 4 2 5.6e-11 4.8e-18 3.7e-05 77 TH1L ZNF831
113 20 61522825 62912463 10 3 1.1e-10 1.5e-10 1.0e+00 100 GMEB2 LIME1 TCEA2
114 22 27445437 28889735 1 1 2.3e-07 1.1e-09 1.0e-03 71 MN1
115 22 40195017 41004384 2 1 3.2e-08 1.7e-08 2.0e-02 83 ADSL

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Bipolar Disorder or Schizophrenia 2.02 12 4 8.9 0.09 7.8e-01 C1orf167 CERS5 FES FURIN GIGYF1 MSRA NAT8 NT5C2 RP11-261C10.5 RP11-282O18.3 SETD8 U91328.21
Depressed Affect (Nagel 2018) 1.74 8 4 8.9 -0.28 5.1e-01 ACP2 ARNTL LINC00461 MPHOSPH9 PPTC7 RERE RNF123 RP11-261C10.5
Depression (Nagel 2018) 1.48 1 0 0.0 0.00 1.0e+00 RERE
Intelligence (Savage-Jansen 2018) 1.54 13 6 13.3 -0.71 6.3e-03 ABCB9 CTNNB1 DCAF16 ERAP2 IRAK1BP1 LINC00461 LMOD1 MPHOSPH9 NAT8 RNF123 RP11-282O18.3 SETD8 SLC5A11
Neuroticism (Nagel 2018) 1.41 6 3 6.7 -0.47 3.5e-01 ACP2 ADM ARNTL FURIN LINC00461 RERE
Schizophrenia (2018) 2.11 6 4 8.9 -0.36 4.9e-01 ABCB9 FES FURIN NT5C2 RP11-261C10.5 U91328.21
Schizophrenia vs Biploar Disorder 1.84 2 0 0.0 0.00 1.0e+00 GPN3 PPTC7
Worry (Nagel 2018) 1.18 2 0 0.0 0.00 1.0e+00 ADM NT5C2
Alzheimer’s Disease (including proxy) 1.49 4 3 6.7 -1.00 3.7e-03 C16orf93 PRSS53 STAG3 ZKSCAN1
Crohns Disease (2017) 1.90 6 4 8.9 0.48 3.4e-01 AGPAT2 ERAP2 LIME1 RNF123 RP11-436D10.3 SNX32
Irritable Bowel Disease (IBD) 1.96 10 4 8.9 0.66 3.9e-02 AGPAT2 ERAP2 GIGYF1 GMEB2 LIME1 LSP1 RNF123 RP11-436D10.3 TNNI2 TRIP6
Ulcerative Colitis (UC) 1.66 4 3 6.7 -0.87 1.3e-01 LIME1 LSP1 RNF123 TNNI2
Major Depression (MDD) 1.28 1 0 0.0 0.00 1.0e+00 NT5C2
Reaction Time 1.87 6 4 8.9 0.99 2.4e-04 ADAM1A ALDH2 BRAP ERP29 NAA25 SH2B3
Verbal and Numeric Reasoning (VNR) 1.64 9 4 8.9 -0.81 7.6e-03 ABCB9 DCAF16 IRAK1BP1 LINC00461 MPHOSPH9 NAT8 RNF123 SLC5A11 U91328.21
Breast Cancer 2.13 9 5 11.1 0.20 6.1e-01 ADSL CPEB4 FES FIBP FURIN MLLT10 RP11-436D10.3 SNX32 TNNT3
Ovarian Cancer 1.07 2 1 2.2 0.00 1.0e+00 ABO MLLT10
Prostate Cancer 1.59 1 0 0.0 0.00 1.0e+00 LIME1
Age at First Birth 1.74 1 1 2.2 0.00 1.0e+00 RNF123
Body Mass Index (BMI) (2010) 1.84 1 0 0.0 0.00 1.0e+00 STAG3L1
Coronary Artery Disease (CAD) 2.46 4 2 4.4 0.34 6.6e-01 ABO ADAMTS7 ALDH2 BRAP
Crohns Disease (2012) 1.80 4 3 6.7 0.51 4.9e-01 ERAP2 LIME1 RNF123 RP11-436D10.3
Fasting Glucose 1.41 1 1 2.2 0.00 1.0e+00 ACP2
HbA1C 1.18 1 0 0.0 0.00 1.0e+00 ADAM1A
HDL Cholesterol 1.72 5 1 2.2 -0.48 4.1e-01 ACP2 ADRB1 CTSW SIPA1 SNX32
LDL Cholesterol 1.76 5 4 8.9 -0.94 1.6e-02 ABO ALDH2 BRAP ERP29 SH2B3
Neuroticism (2016) 1.56 4 1 2.2 -0.57 4.3e-01 ADM LINC00461 MSRA RP11-462G12.1
Primary Biliary Cirrhosis 1.65 4 1 2.2 0.73 2.7e-01 ALDH2 ERP29 MANBA SH2B3
Rheumatoid Arthritis 1.28 1 0 0.0 0.00 1.0e+00 SH2B3
Schizophrenia (2014) 2.08 13 4 8.9 -0.12 6.7e-01 ABCB9 CERS5 DYNC1I2 FES FURIN GIGYF1 MPHOSPH9 MSRA NT5C2 RERE RP11-261C10.5 RP11-282O18.3 SETD8
Triglycerides 1.34 3 1 2.2 0.00 1.0e+00 MSRA NRBF2 PRSS53
Ulcerative Colitis 1.59 4 2 4.4 -0.70 3.0e-01 LIME1 LSP1 RNF123 TNNI2
Blood Eosinophil Count 5.48 37 30 66.7 0.65 2.6e-06 ABCB9 ABO ACVR2A ADAM1A ADRA2B ALDH2 ARRB2 BRAP C16orf93 CD164 CERS5 CPEB4 CTSW EHD4 ERAP2 ERP29 FIBP GIGYF1 GIMAP7 GPN3 HAUS4 MAP3K11 MED19 MPHOSPH9 NAA25 PITPNM2 PPTC7 PRSS53 RERE RP11-282O18.3 RP5-1029K10.2 RPAP1 SH2B3 SIPA1 SNX32 VPS29 ZNF831
Blood Platelet Count 3.10 48 42 93.3 0.16 2.4e-01 ABCB9 ADAM1A ADAMTS7 ALDH2 ANKFY1 C11orf67 C16orf93 C20orf160 C4orf3 CD164 CERS5 CLCN6 CTSW DCAF16 EDEM3 ERP29 FIBP FLNB GMEB2 GPN3 HAUS8 IPO11 IRAK1BP1 KRT8P33 LIME1 LINC00461 MPHOSPH9 MTHFR NAA25 NMT1 NOV NRBF2 PITPNM2 PPTC7 REEP3 RP11-282O18.3 RP11-436D10.3 RP11-462G12.1 RP11-91P24.7 RP5-1029K10.2 SETD8 SH2B3 SIPA1 SLC25A37 SNX32 STXBP5 TH1L VPS29
Blood Red Count 2.68 49 33 73.3 0.60 7.3e-07 ABCB9 ABO ACHE ACVR2A ADAM1A ADM ALDH2 ARNTL BRAP C20orf160 C4orf22 C8orf38 CCNE1 CD164 CLCN6 CPEB4 CYB5D1 ERP29 EXD1 GIGYF1 GMEB2 GPN3 HYI INO80 LIME1 LINC00461 LOC100129961 LSP1 MPI NAA25 NAT8 NME6 NT5C2 PKHD1 PPTC7 PRSS53 REEP3 RNF123 RP11-23P13.4 SETD8 SH2B3 SLC9A3R2 SNX32 TH1L TMEM87B ULK4 USP36 VPS29 ZNF100
Blood White Count 3.26 41 28 62.2 0.62 8.9e-06 ABO ADAM1A ALDH2 ARHGAP42 ARRB2 BRAP C10orf118 C16orf93 C4orf3 CD164 CEP85L CERS5 CMIP CYB5D1 DCAF16 ERAP2 ERP29 FES FIBP FLNB FURIN GPN3 LIME1 LSP1 NAA25 NRBF2 NT5C2 PPTC7 PRSS53 REEP3 RERE RNF123 RP11-23P13.4 RP5-1029K10.2 SH2B3 SLC5A11 SLC9A3R2 SRR TMEM87B TNNI2 VPS29
Heel T-Score 2.35 52 38 84.4 0.15 2.7e-01 ABCB9 ABO ACHE ACP2 ADRA2B ADSL ANKFY1 ARHGAP42 C11orf67 C16orf93 C17orf81 C20orf160 CASP7 CD164 CMIP CPEB4 CTNNB1 CTSW CYB5D1 DCAF16 EVX1 FLNB GIGYF1 GLS JAG1 KRT8P33 LOC338758 MAP3K11 MPHOSPH9 NMT1 NT5C2 PDE1A PITPNM2 PRSS53 RERE RNF123 RP11-282O18.3 RP11-462G12.1 SCMH1 SETD8 SF3A3 SIPA1 SLC5A11 SLC9A3R2 SNTB2 SNX32 SRR TH1L THSD4 TMEM87B TRIP6 WNT2B
BMI 2.61 43 26 57.8 0.71 4.9e-08 ABCB9 ADSL ANKFY1 ARNTL C16orf93 C17orf81 C20orf160 C4orf22 CCNE1 CHP1 CLCN6 CPEB4 CTNNB1 CTSW DYNC1I2 EDEM3 FAM108C1 FIBP GPN3 IFT57 LIME1 LINC00461 LMOD1 LOC100129961 MANBA MLLT10 NCF1 NRBF2 NT5C2 PITPNM2 PPTC7 PRSS53 REEP3 RNF123 RP11-462G12.1 SLC25A37 SLC5A11 SLC9A3R2 SNX32 SRR STAG3L1 STXBP5 USP36
Height 2.03 71 56 124.4 -0.29 1.2e-02 ABCB9 ABO ACHE ACP2 ADM ADRB1 AGPAT2 ALDH2 ARHGAP42 BCKDHB BRAP C11orf67 C16orf93 CCNE1 CD164 CEP152 CERS5 CHP1 CTNNB1 CTSW DCAF16 DYNC1I2 EDEM3 EIF5A ERP29 EVX1 EXD1 FES FURIN GIGYF1 GIMAP7 HYI INO80 JAG1 KRT8P33 KTN1-AS1 LSP1 MED19 MN1 MPHOSPH9 MSTN NMT1 NOV PDE1A PITPNM2 PPTC7 REEP3 RNF123 RP11-282O18.3 RP11-436D10.3 RP11-462G12.1 RP11-91P24.7 RP5-1029K10.2 RPAP1 RPL39P5 RSRC1 RYK SCMH1 SETD8 SF3A3 SH2B3 SLC24A3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 TNNT3 TRIP6 USP36 WNT2B ZNF831
Waist Hip Ratio (WHR) 1.88 22 15 33.3 0.41 4.7e-02 ABCB9 ADAM1A ADAMTS8 ADM ANKFY1 BCKDHB CMIP CPEB4 CTSW DYNC1I2 EHD4 EIF5A HAUS8 JMJD7-PLA2G4B MAP3K11 MPHOSPH9 RP11-23P13.4 RP11-282O18.3 SETD8 SIPA1 SWAP70 TCEA2
Systolic Blood Pressure 11.66 113 99 220.0 0.88 3.4e-43 AC099850.1 ACP2 ADAM1A ADAMTS8 ADM ADRB1 AGT ALDH2 ARHGAP42 ARNTL ATP2B1 BRAP C10orf118 C17orf81 C1GALT1 C1orf167 C20orf160 C4orf22 C4orf3 CACNB2 CCDC148 CDH13 CERS5 CHP1 CLCN6 CMIP CPEB4 CSTA CTSW CYB5D1 DCAF16 EDEM3 EHD4 EIF2AK4 ERAP2 ERP29 EVX1 EXD1 FAM108C1 FES FIBP FURIN GIMAP7 GLS GMEB2 GPN3 HAUS4 HAUS8 HYI IGFBP3 INO80 IPO11 IRAK1BP1 ITGB5 JMJD7-PLA2G4B KRT8P33 LIME1 LOC100129961 LOC338758 LSP1 MAP3K11 MED19 MPI MSTN MTHFR NAA25 NME6 NMT1 NOC3L NOV NRBF2 NSUN6 NT5C2 PDE1A PPP3CA PPTC7 REEP3 RERE RNF123 RP11-23P13.4 RP11-436D10.3 RP11-819C21.1 RP5-1029K10.2 RPAP1 RPL39P5 RSRC1 RYK SCMH1 SH2B3 SIPA1 SIRT4 SLC16A1 SLC24A3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 SRR STAG3L1 STXBP5 SWAP70 TCEA2 TENC1 TH1L TMEM87B TNNI2 TNNT3 ULK4 USP36 VPS29 WNT2B ZNF100 ZNF831
Smoking Status 1.44 9 3 6.7 0.22 5.7e-01 ADAM1A CPEB4 CTSW FES MLLT10 RERE SLC5A11 SNX32 SRR
Allergy or Eczema 2.43 18 9 20.0 0.47 5.0e-02 ABCB9 ABO ADAM1A CHP1 CLCN6 EXD1 GMEB2 INO80 LIME1 MANBA MAP3K11 MPHOSPH9 MPI RERE RP11-282O18.3 RP5-1029K10.2 RPAP1 SRR
Cardiovascular Disease 8.44 83 58 128.9 0.97 8.0e-62 ACP2 ADAM1A ADRB1 AGT ALDH2 ANKFY1 ARHGAP42 ARNTL ATP2B1 BRAP C10orf118 C16orf93 C1GALT1 C1orf167 C20orf160 C4orf22 C8orf38 CACNB2 CCDC148 CERS5 CHP1 CLCN6 CMIP CPEB4 CTSW CYB5D1 DCAF16 EHD4 ERP29 EVX1 EXD1 FAM108C1 FES FURIN GIMAP7 GMEB2 HAUS8 INO80 IRAK1BP1 ITGB5 LIME1 LOC338758 LSP1 MANBA MAP3K11 MPHOSPH9 MPI MTHFR NAA25 NCF1 NME6 NMT1 NOC3L NRBF2 NSUN6 NT5C2 PDE1A PKHD1 PRSS53 RP11-23P13.4 RP11-261C10.5 RP11-436D10.3 RP11-462G12.1 RP11-819C21.1 RP5-1029K10.2 RPAP1 RYK SH2B3 SIPA1 SNX32 STAG3 STAG3L1 SWAP70 TCEA2 TH1L TNNI2 TNNT3 USP36 VPS29 WNT2B ZKSCAN1 ZNF100 ZNF831
Hypothyroidism (self reported) 3.75 10 8 17.8 0.66 9.7e-03 ADAM1A ALDH2 BRAP ERP29 GIGYF1 NAA25 RERE SH2B3 SLC25A37 VPS29
Respiratory disease 1.51 6 3 6.7 0.99 1.9e-04 CHP1 GMEB2 LIME1 NMT1 RERE RP5-1029K10.2
Type 2 Diabetes (T2D) (2018) 2.41 7 3 6.7 0.93 3.0e-04 ANKFY1 C1GALT1 CTSW MPHOSPH9 RNF123 SH2B3 SNX32
Lung FEV1/FVC ratio 3.07 30 18 40.0 0.19 3.2e-01 ABO ADM ADSL ANKFY1 ARHGAP42 ATP2B1 C16orf93 C1GALT1 CACNB2 CD164 CPEB4 CTNNB1 CYB5D1 EHD4 HAUS4 JMJD7-PLA2G4B KRT8P33 MLLT10 NRBF2 RERE RP11-23P13.4 RP11-436D10.3 RP5-1029K10.2 RPAP1 SLC24A3 STAG3 STEAP1 THSD4 ULK4 ZKSCAN1
Lung FVC 1.53 19 12 26.7 -0.09 7.1e-01 ABCB9 ANKFY1 C1GALT1 CHP1 DCAF16 EXD1 GMEB2 INO80 JAG1 LIME1 LOC100129961 MLLT10 MPHOSPH9 NRBF2 PRSS53 RP11-282O18.3 RSRC1 SETD8 THSD4
Neuroticism 1.39 7 2 4.4 -0.56 1.9e-01 ADM ARNTL CASP7 DYNC1I2 FURIN LINC00461 RERE
Chronotype (morning person) 1.30 5 1 2.2 0.98 2.7e-03 ADAM1A ALDH2 BRAP ERP29 NAA25
Hair Pigment 0.41 26 22 48.9 -0.21 2.6e-01 ABCB9 ACHE ACP2 ADM ALDH2 ATP2B1 BRAP C20orf160 C4orf22 CTSW ERP29 FES GIGYF1 INTS4 LOC100129961 MAP3K11 MPHOSPH9 RERE RP11-282O18.3 RP11-91P24.7 SETD8 SH2B3 SIPA1 SNX32 TRIP6 ZNF831
Tanning 0.24 5 2 4.4 0.40 5.0e-01 ALDH2 ERP29 NRBF2 RP11-436D10.3 SH2B3
Hand grip strength (left) 1.59 7 4 8.9 -0.13 7.9e-01 ADSL DCAF16 JAG1 LOC100129961 SLC5A11 SLC9A3R2 WNT2B
Number of treatments/medications taken 3.14 14 6 13.3 0.95 2.3e-07 ADAM1A ALDH2 ARHGAP42 C1GALT1 CHP1 DCAF16 EHD4 ERP29 FAM108C1 MANBA MLLT10 RNF123 SH2B3 ZNF831
Sensitivity / hurt feelings 1.46 4 2 4.4 -0.96 3.9e-02 AC099850.1 FES FURIN MSRA
Hearing difficulty/problems: Yes 0.84 1 0 0.0 0.00 1.0e+00 C17orf81
Relative age of first facial hair 1.08 3 1 2.2 0.00 1.0e+00 C4orf22 MAP3K11 REEP3
Ever had hysterectomy (womb removed) 1.35 1 0 0.0 0.00 1.0e+00 MLLT10
Systolic blood pressure, automated reading 9.68 92 73 162.2 0.90 3.6e-38 AC099850.1 ACP2 ADAM1A ADAMTS8 ADM ADRB1 AGT ALDH2 ARHGAP42 ARNTL ATP2B1 BRAP C17orf81 C1orf167 C4orf22 CACNB2 CCDC148 CD164 CERS5 CHP1 CLCN6 CPEB4 CTSW DCAF16 DYNC1I2 EDEM3 EIF2AK4 ERP29 EVX1 EXD1 FAM108C1 FES FIBP FURIN GIMAP7 GMEB2 HAUS4 HAUS8 HYI IGFBP3 INO80 IPO11 IRAK1BP1 ITGB5 LIME1 LOC100129961 LOC338758 LSP1 MAP3K11 MED19 MPI MSRA MSTN MTHFR NAA25 NCF1 NEIL2 NME6 NMT1 NOC3L NOV NRBF2 NSUN6 NT5C2 PPTC7 RERE RNF123 RP11-23P13.4 RP11-436D10.3 RP11-819C21.1 RP5-1029K10.2 RSRC1 SCMH1 SH2B3 SIPA1 SLC16A1 SLC5A11 SLC9A3R2 SNX32 SRR STAG3L1 STXBP5 SWAP70 TCEA2 TH1L TMEM87B TNNI2 TNNT3 ULK4 USP36 WNT2B ZNF831
Angina 1.85 3 3 6.7 0.00 1.0e+00 ADAMTS7 FES FURIN
Vitamin and mineral supplements 1.19 1 0 0.0 0.00 1.0e+00 REEP3
Medication: Metformin 1.82 2 0 0.0 0.00 1.0e+00 MANBA MPHOSPH9
Pack years adult smoking proportion 1.51 1 1 2.2 0.00 1.0e+00 ADAMTS7
Impedance of leg (right) 2.06 37 26 57.8 -0.18 2.7e-01 ADM ADRA2B ADSL ARHGAP42 C16orf93 C4orf3 CCNE1 CERS5 CTSW FAM108C1 FES FIBP FURIN GIMAP7 GNAO1 HAUS8 IGFBP3 JMJD7-PLA2G4B KRT8P33 LINC00461 LMOD1 MSRA NCF1 NMT1 NOC3L NT5C2 PRSS53 RNF123 RP11-23P13.4 RP11-462G12.1 RP5-1029K10.2 SNX32 SRR STAG3L1 SWAP70 TH1L ULK4
Leg fat-free mass (left) 2.32 41 29 64.4 0.23 1.6e-01 ADM ADSL ALDH2 BCKDHB C10orf118 C16orf93 CCNE1 CD164 CPEB4 CTNNB1 DCAF16 DYNC1I2 FAM108C1 FURIN GPN3 KRT8P33 LINC00461 LMOD1 MLLT10 MPHOSPH9 MSRA NMT1 NOV NT5C2 PDE1A PPTC7 PRSS53 RNF123 RP11-282O18.3 RP11-436D10.3 RP11-462G12.1 SCMH1 SF3A3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 ULK4 USP36 VPS29
Trunk fat percentage 2.41 30 16 35.6 0.76 1.4e-06 ABO ADM ARNTL C16orf93 C17orf81 CCDC148 CCNE1 CHP1 CLCN6 CTNNB1 CTSW EDEM3 EVX1 LIME1 LINC00461 LMOD1 LOC100129961 MLLT10 NCF1 NOC3L PITPNM2 PRSS53 RERE RNF123 RP11-462G12.1 RPAP1 SLC25A37 SLC5A11 SNX32 STAG3L1
Hand grip strength (right) 1.73 12 4 8.9 -0.12 6.9e-01 ACHE C11orf67 DCAF16 JAG1 LOC100129961 MLLT10 NMT1 SCMH1 SLC5A11 SLC9A3R2 TRIP6 WNT2B
Current tobacco smoking 1.63 2 0 0.0 0.00 1.0e+00 MSRA SLC5A11
Average weekly fortified wine intake 1.12 1 0 0.0 0.00 1.0e+00 SLC5A11
Maternal smoking around birth 1.59 4 1 2.2 0.99 5.6e-03 C20orf160 MLLT10 RNF123 SLC5A11
Fed-up feelings 1.92 10 3 6.7 -0.43 2.2e-01 ALDH2 ARNTL BRAP ERP29 LINC00461 MPHOSPH9 MSRA RNF123 SH2B3 SLC5A11
Taking other prescription medications 1.88 5 2 4.4 0.98 4.4e-03 ADAM1A ALDH2 ERP29 RNF123 SH2B3
Age when periods started (menarche) 1.83 11 5 11.1 -0.99 2.2e-11 ARNTL CTSW EXD1 FIBP INO80 LSP1 NCF1 SNX32 STAG3L1 STXBP5 TNNI2
Bilateral oophorectomy (both ovaries removed) 1.38 1 0 0.0 0.00 1.0e+00 MLLT10
Heel bone mineral density (BMD) T-score, automated (left) 1.88 8 5 11.1 0.39 3.4e-01 CMIP CYB5D1 JAG1 MAP3K11 MSRA RERE RNF123 SIPA1
High blood pressure 8.83 82 55 122.2 0.97 1.6e-57 ABO ACP2 ADAM1A ADRB1 AGT ALDH2 ARHGAP42 ARNTL ATP2B1 BRAP C10orf118 C16orf93 C1GALT1 C1orf167 C20orf160 C4orf22 CACNB2 CCDC148 CCNE1 CERS5 CHP1 CLCN6 CMIP CTSW CYB5D1 DCAF16 EDEM3 ERP29 EVX1 EXD1 FAM108C1 FES FURIN GMEB2 HAUS8 INO80 IRAK1BP1 ITGB5 LIME1 LOC338758 LSP1 MANBA MLLT10 MPI MSRA MTHFR NAA25 NCF1 NEIL2 NME6 NMT1 NOC3L NRBF2 NSUN6 NT5C2 PDE1A PPTC7 PRSS53 REEP3 RERE RP11-261C10.5 RP11-436D10.3 RP5-1029K10.2 RPAP1 RSRC1 RYK SH2B3 SIPA1 SLC25A37 SLC5A11 SNX32 SRR STAG3 STAG3L1 SWAP70 TCEA2 TH1L TNNI2 TNNT3 WNT2B ZKSCAN1 ZNF831
Hayfever, allergic rhinitis or eczema 2.14 10 5 11.1 0.81 4.5e-03 ABCB9 ADAM1A CHP1 EXD1 INO80 LIME1 MPHOSPH9 PITPNM2 RERE RP11-282O18.3
Multivitamins +/- minerals 1.25 1 1 2.2 0.00 1.0e+00 REEP3
Supplements: Glucosamine 1.62 2 1 2.2 0.00 1.0e+00 NRBF2 REEP3
Medication: Atenolol 3.31 8 2 4.4 0.97 5.0e-05 ALDH2 ARHGAP42 BRAP CLCN6 ERP29 FES FURIN SH2B3
Medication: Levothyroxine sodium 3.69 8 8 17.8 0.86 7.7e-04 ADAM1A ALDH2 BRAP ERP29 GIGYF1 NAA25 SH2B3 VPS29
Sitting height 2.14 34 23 51.1 -0.23 1.8e-01 ABCB9 ADM ADRB1 AGPAT2 BCKDHB C10orf118 C20orf160 CCNE1 CD164 CERS5 CHP1 CTNNB1 DCAF16 EXD1 FAM108C1 FLNB IGFBP3 JAG1 KRT8P33 MN1 MPHOSPH9 NMT1 NOV PITPNM2 RP11-282O18.3 RP11-436D10.3 RP5-1029K10.2 RPL39P5 RSRC1 SCMH1 SETD8 SF3A3 SLC9A3R2 ZNF831
High blood pressure (mother) 3.77 8 2 4.4 0.93 1.2e-04 AGT ARHGAP42 CLCN6 FES FURIN ITGB5 TNNT3 ZNF831
Body mass index (BMI) 2.84 32 18 40.0 0.84 4.5e-10 ABCB9 ADSL ARNTL C16orf93 C17orf81 CCDC148 CCNE1 CTSW DYNC1I2 EDEM3 FIBP GPN3 IFT57 LINC00461 LMOD1 LOC100129961 MLLT10 MSRA NCF1 PITPNM2 PPTC7 PRSS53 REEP3 RERE RNF123 RP11-462G12.1 SLC25A37 SLC5A11 SLC9A3R2 SNX32 SRR STAG3L1
Impedance of leg (left) 2.01 35 25 55.6 -0.18 2.7e-01 ADM ADRA2B ADSL ARHGAP42 C16orf93 C4orf3 CCNE1 CERS5 CTSW FAM108C1 FES FIBP FURIN GIMAP7 GNAO1 HAUS8 IGFBP3 JMJD7-PLA2G4B KRT8P33 LINC00461 LMOD1 MSRA NMT1 NOC3L NT5C2 PRSS53 RNF123 RP11-23P13.4 RP11-462G12.1 RP5-1029K10.2 SNX32 SRR STAG3L1 SWAP70 ULK4
Leg predicted mass (left) 2.32 41 27 60.0 0.23 1.5e-01 ADM ADSL ALDH2 BCKDHB C10orf118 C16orf93 CCNE1 CD164 CPEB4 CTNNB1 DCAF16 DYNC1I2 FAM108C1 FURIN GPN3 KRT8P33 LINC00461 LMOD1 MLLT10 MPHOSPH9 MSRA NMT1 NOV NT5C2 PDE1A PPTC7 PRSS53 RNF123 RP11-282O18.3 RP11-436D10.3 RP11-462G12.1 SCMH1 SF3A3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 ULK4 USP36 VPS29
Trunk fat mass 2.46 31 21 46.7 0.77 2.6e-07 ARNTL C16orf93 C17orf81 C8orf38 CCNE1 CTNNB1 CTSW DYNC1I2 EDEM3 EIF5A EVX1 GPN3 LIME1 LINC00461 LMOD1 LOC100129961 MLLT10 MSRA NCF1 PITPNM2 PPTC7 PRSS53 RERE RNF123 RP11-462G12.1 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 USP36
Waist circumference 2.67 26 16 35.6 0.92 3.6e-12 ADSL ARNTL C16orf93 C17orf81 CCDC148 CCNE1 CMIP CTNNB1 CTSW FAM108C1 FIBP IFT57 LIME1 LINC00461 LMOD1 MLLT10 NCF1 PRSS53 RNF123 RP11-462G12.1 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 USP36
Number of incorrect matches in round 1.23 4 2 4.4 -1.00 4.0e-03 FES FURIN LOC100129961 PRSS53
Past tobacco smoking 1.74 7 1 2.2 -0.78 2.1e-02 ADAM1A ALDH2 BRAP ERP29 MLLT10 SH2B3 SRR
Nervous feelings 1.23 3 1 2.2 0.00 1.0e+00 ADM ARNTL MSRA
Hair/balding pattern: Pattern 2 1.18 1 1 2.2 0.00 1.0e+00 C4orf22
Had menopause 1.66 3 0 0.0 0.00 1.0e+00 CHP1 EXD1 INO80
Forced vital capacity (FVC) 1.83 18 11 24.4 -0.09 7.3e-01 ACHE BCKDHB C11orf67 CTNNB1 DCAF16 FLNB GMEB2 JAG1 LIME1 LOC100129961 MLLT10 MN1 NOV RP11-91P24.7 RSRC1 SCMH1 TRIP6 U91328.21
Heel bone mineral density (BMD) T-score, automated (right) 1.87 9 5 11.1 0.40 2.9e-01 ACP2 CYB5D1 DCAF16 MAP3K11 MSRA RERE RNF123 SIPA1 WNT2B
Qualifications: None of the above 1.72 7 6 13.3 0.99 4.2e-07 ABCB9 IRAK1BP1 MPHOSPH9 RNF123 RP11-282O18.3 SETD8 SLC5A11
Financial difficulties in last 2 years 1.22 1 0 0.0 0.00 1.0e+00 PRSS53
Mouth/teeth dental problems 1.42 2 0 0.0 0.00 1.0e+00 NCF1 RP11-261C10.5
Heart attack 1.99 1 1 2.2 0.00 1.0e+00 FES
Allergy 2.24 14 8 17.8 -0.62 1.7e-02 ABCB9 ABO CHP1 EXD1 FES GMEB2 INO80 LIME1 MANBA MPHOSPH9 RERE RP11-282O18.3 RP5-1029K10.2 SETD8
Diabetes (self-reported) 1.76 3 1 2.2 0.00 1.0e+00 C1GALT1 MPHOSPH9 RNF123
Medication: Ramipril 3.01 4 1 2.2 1.00 1.8e-03 ADAM1A ARHGAP42 CMIP FES
Medication: Simvastatin 2.21 3 1 2.2 0.00 1.0e+00 ABO FES ZNF831
Fluid intelligence score 1.55 7 2 4.4 -0.98 1.4e-04 DCAF16 LMOD1 MPHOSPH9 RNF123 RP11-282O18.3 SETD8 U91328.21
Illnesses of siblings 3.00 5 1 2.2 -0.96 2.6e-03 CLCN6 FES PRSS53 SH2B3 SLC5A11
Neuroticism score 1.64 7 3 6.7 -0.62 1.4e-01 ADM ARNTL CASP7 LINC00461 MPHOSPH9 MSRA RERE
Weight 2.55 41 29 64.4 0.49 9.0e-04 ADSL ALDH2 BCKDHB BRAP C10orf118 C16orf93 C17orf81 C8orf38 CCNE1 CD164 CTNNB1 CTSW DCAF16 DYNC1I2 EIF5A FAM108C1 FIBP GPN3 IFT57 KRT8P33 LIME1 LINC00461 LMOD1 MLLT10 MSRA NCF1 PPTC7 PRSS53 RNF123 RP11-282O18.3 RP11-436D10.3 RP11-462G12.1 SCMH1 SF3A3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 USP36 VPS29
Impedance of arm (right) 2.13 29 16 35.6 -0.38 3.3e-02 ABO ADAMTS8 ADM ADSL CERS5 CMIP CTSW EVX1 FIBP GPN3 HAUS8 KTN1-AS1 LMOD1 LSP1 MANBA MLLT10 MSRA NOC3L NRBF2 PDE1A PPTC7 PRSS53 RNF123 RP11-462G12.1 RP5-1029K10.2 SLC9A3R2 SNX32 STAG3L1 VPS29
Arm fat percentage (right) 2.60 34 23 51.1 0.79 1.0e-08 ABCB9 ABO ADM ARNTL C16orf93 C17orf81 CCDC148 CCNE1 CHP1 CLCN6 CTSW DCAF16 EDEM3 EVX1 EXD1 IFT57 LINC00461 LMOD1 LOC100129961 MLLT10 MSRA NCF1 PITPNM2 PRSS53 RERE RNF123 RP11-462G12.1 RPAP1 SLC25A37 SLC5A11 SNX32 SRR STAG3L1 STXBP5
Trunk fat-free mass 2.39 42 34 75.6 -0.12 4.3e-01 ABCB9 ABO ADM ADSL ALDH2 BCKDHB BRAP C10orf118 C16orf93 CCNE1 CD164 CTNNB1 DCAF16 DYNC1I2 ERP29 FAM108C1 GPN3 HAUS8 KRT8P33 LMOD1 MN1 MPHOSPH9 NMT1 NOV PDE1A PPTC7 PRSS53 RNF123 RP11-282O18.3 RP11-436D10.3 RP11-462G12.1 RPL39P5 SCMH1 SETD8 SF3A3 SH2B3 SLC25A37 SLC5A11 SLC9A3R2 ULK4 USP36 VPS29
Hip circumference 2.53 35 23 51.1 0.24 1.5e-01 ALDH2 BRAP C16orf93 C17orf81 CCNE1 CLCN6 CPEB4 CTNNB1 DCAF16 DYNC1I2 EIF5A ERP29 FAM108C1 GPN3 IFT57 LIME1 LINC00461 LMOD1 LOC100129961 MLLT10 MSRA NCF1 PPTC7 PRSS53 RNF123 RP11-282O18.3 RP11-462G12.1 SH2B3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 USP36 VPS29
Alcohol intake versus 10 years previously 1.53 1 1 2.2 0.00 1.0e+00 RNF123
Father's age at death 2.56 4 2 4.4 -0.73 2.7e-01 ABO FES MPHOSPH9 SH2B3
Worrier / anxious feelings 1.48 3 1 2.2 0.00 1.0e+00 ARNTL MSRA RP11-462G12.1
Frequency of tiredness / lethargy in last 2 weeks 1.47 3 0 0.0 0.00 1.0e+00 BRAP LMOD1 RERE
Hair/balding pattern: Pattern 3 1.55 1 1 2.2 0.00 1.0e+00 C4orf22
Forced expiratory volume in 1-second (FEV1) 1.87 20 11 24.4 -0.17 4.6e-01 ARHGAP42 BCKDHB C11orf67 C1GALT1 CD164 CTNNB1 DCAF16 FLNB JAG1 LIME1 LOC100129961 MN1 MSRA NRBF2 PRSS53 RSRC1 SCMH1 THSD4 U91328.21 ULK4
Pulse rate 3.50 7 5 11.1 0.98 8.1e-07 AC005517.3 ACHE CEP85L CTNNB1 GIGYF1 STAG3 TRIP6
Qualifications: A levels/AS levels or equivalent 2.18 10 6 13.3 -0.95 2.5e-06 ABCB9 DCAF16 MPHOSPH9 MSRA RNF123 RP11-261C10.5 RP11-282O18.3 SETD8 SLC5A11 STAG3L1
Mouth/teeth dental problems: Dentures 1.41 2 0 0.0 0.00 1.0e+00 MSRA RNF123
Asthma 1.57 4 1 2.2 0.62 3.8e-01 LIME1 RERE RP5-1029K10.2 U91328.21
Medication: Ibuprofen (e.g. Nurofen) 1.52 1 0 0.0 0.00 1.0e+00 U91328.21
Medication: Cholesterol lowering 2.37 6 1 2.2 0.54 2.7e-01 ABO ARHGAP42 CHP1 CLCN6 FES ZNF831
Depression (self-reported) 1.00 1 0 0.0 0.00 1.0e+00 RERE
Lung cancer (father) 1.36 1 0 0.0 0.00 1.0e+00 ADAMTS7
Illnesses of mother 2.26 1 1 2.2 0.00 1.0e+00 FES
Forced expiratory volume in 1-second (FEV1), Best measure 1.84 17 9 20.0 -0.12 6.4e-01 ABO BCKDHB C1GALT1 CTNNB1 DCAF16 FLNB JAG1 KRT8P33 LIME1 LOC100129961 MN1 NRBF2 PRSS53 RSRC1 SCMH1 THSD4 U91328.21
Pulse wave Arterial Stiffness index 1.97 1 1 2.2 0.00 1.0e+00 ADAM1A
Impedance of arm (left) 2.13 32 17 37.8 -0.35 4.2e-02 ABO ADAMTS8 ADM ADSL ALDH2 CERS5 CMIP CTSW EVX1 FAM108C1 FIBP GPN3 KTN1-AS1 LMOD1 LSP1 MANBA MLLT10 MSRA NOC3L NRBF2 PDE1A PPTC7 PRSS53 RNF123 RP11-462G12.1 RP5-1029K10.2 SH2B3 SLC9A3R2 SNX32 STAG3L1 TNNT3 VPS29
Arm fat mass (right) 2.68 35 17 37.8 0.79 7.3e-09 ADSL ARNTL C16orf93 C17orf81 CCNE1 CLCN6 CTNNB1 CTSW DYNC1I2 EDEM3 EIF5A FIBP GPN3 IFT57 LIME1 LINC00461 LMOD1 LOC100129961 MLLT10 MSRA NCF1 PITPNM2 PPTC7 PRSS53 RERE RNF123 RP11-462G12.1 SLC25A37 SLC5A11 SLC9A3R2 SNX32 SRR STAG3L1 STXBP5 USP36
Trunk predicted mass 2.39 42 34 75.6 -0.13 4.1e-01 ABCB9 ABO ADM ADSL ALDH2 BCKDHB BRAP C10orf118 C16orf93 CCNE1 CD164 CTNNB1 DCAF16 DYNC1I2 ERP29 FAM108C1 GPN3 HAUS8 KRT8P33 LMOD1 MN1 MPHOSPH9 NMT1 NOV PDE1A PPTC7 PRSS53 RNF123 RP11-282O18.3 RP11-436D10.3 RP11-462G12.1 RPL39P5 SCMH1 SETD8 SF3A3 SH2B3 SLC25A37 SLC5A11 SLC9A3R2 ULK4 USP36 VPS29
Standing height 1.96 53 35 77.8 -0.28 3.7e-02 ABCB9 ACHE ACP2 ACVR2A ADM ADRB1 AGPAT2 ALDH2 BCKDHB BRAP C10orf118 C11orf67 CCNE1 CD164 CEP152 CERS5 CHP1 CTNNB1 CTSW DCAF16 DYNC1I2 EDEM3 EXD1 INO80 JAG1 KRT8P33 MN1 MPHOSPH9 MSRA NMT1 NOV PDE1A PITPNM2 REEP3 RP11-282O18.3 RP11-436D10.3 RP11-462G12.1 RP11-91P24.7 RP5-1029K10.2 RPL39P5 RYK SCMH1 SETD8 SF3A3 SH2B3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 TRIP6 USP36 WNT2B ZNF831
Tense / 'highly strung' 1.39 3 1 2.2 0.00 1.0e+00 MSRA NT5C2 RERE
Seen doctor (GP) for nerves, anxiety, tension or depression 1.40 1 0 0.0 0.00 1.0e+00 U91328.21
Hair/balding pattern: Pattern 4 1.55 4 3 6.7 0.48 5.2e-01 C4orf22 CERS5 CTNNB1 SRR
Birth weight of first child 2.88 12 7 15.6 -0.96 7.0e-10 ALDH2 BRAP C1orf167 CLCN6 DCAF16 ERP29 FES FURIN MTHFR SH2B3 SLC25A37 STAG3L1
Peak expiratory flow (PEF) 1.63 7 5 11.1 0.06 8.9e-01 ABO C1GALT1 DCAF16 FLNB MSRA SLC9A3R2 THSD4
Pulse wave reflection index 1.48 1 0 0.0 0.00 1.0e+00 ADAMTS8
Qualifications: O levels/GCSEs or equivalent 1.64 5 3 6.7 -0.98 2.7e-03 ABCB9 MPHOSPH9 RNF123 RP11-282O18.3 SETD8
Blood clot in the leg (DVT) 3.11 1 1 2.2 0.00 1.0e+00 ABO
Medication: Paracetamol 1.72 3 2 4.4 0.00 1.0e+00 MLLT10 RP11-261C10.5 U91328.21
Headache pain in last month 1.77 6 2 4.4 -0.29 5.7e-01 ALDH2 BRAP MED19 RP11-261C10.5 SLC24A3 U91328.21
Medication for cholesterol, blood pressure or diabetes 4.65 17 6 13.3 -0.96 1.3e-11 ARHGAP42 ATP2B1 C4orf22 CHP1 CLCN6 CTSW FAM108C1 FES FURIN LOC338758 MPI MTHFR NME6 RNF123 SH2B3 TH1L ZNF831
Gout (self-reported) 1.50 2 0 0.0 0.00 1.0e+00 SH2B3 SIPA1
Hypothyroidism/myxoedema (self-reported) 3.52 9 9 20.0 0.63 2.2e-02 ADAM1A ALDH2 BRAP ERP29 GIGYF1 MSRA NAA25 SH2B3 VPS29
Medication: Amlodipine 4.12 11 6 13.3 0.92 1.7e-06 ARHGAP42 C1orf167 CLCN6 FAM108C1 FES LSP1 MTHFR SIPA1 TNNI2 TNNT3 WNT2B
Birth weight 2.64 12 10 22.2 -0.52 6.7e-02 ADAM1A ADRB1 ALDH2 BRAP C17orf81 DCAF16 ERP29 FES FURIN SH2B3 SRR TMEM87B
High blood pressure (siblings) 3.71 8 3 6.7 0.97 3.6e-07 ACP2 ARHGAP42 CLCN6 FES NRBF2 PRSS53 SH2B3 TNNT3
Forced vital capacity (FVC), Best measure 1.74 19 9 20.0 -0.22 3.6e-01 ACHE ACP2 BCKDHB C11orf67 CTNNB1 DCAF16 FLNB GMEB2 JAG1 LIME1 LOC100129961 MLLT10 MN1 NOV PRSS53 RSRC1 SCMH1 TRIP6 U91328.21
Body fat percentage 2.65 34 18 40.0 0.79 1.5e-08 ABCB9 ABO ADM ARNTL C16orf93 C17orf81 CCDC148 CCNE1 CHP1 CLCN6 CTSW DCAF16 EDEM3 EVX1 EXD1 LIME1 LINC00461 LMOD1 LOC100129961 MLLT10 MSRA NCF1 NOC3L PITPNM2 PRSS53 RERE RNF123 RP11-462G12.1 RPAP1 SLC25A37 SLC5A11 SNX32 STAG3L1 STXBP5
Leg fat percentage (right) 2.93 37 20 44.4 0.83 7.4e-11 ABCB9 ADM ARNTL C17orf81 C8orf38 CCDC148 CCNE1 CHP1 CLCN6 CTSW DCAF16 EDEM3 EXD1 FIBP GPN3 LIME1 LINC00461 LMOD1 LOC100129961 MLLT10 MPHOSPH9 MSRA NCF1 NMT1 PITPNM2 PRSS53 REEP3 RERE RNF123 RP11-462G12.1 RPAP1 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 STXBP5
Arm fat-free mass (right) 2.54 46 35 77.8 0.07 6.6e-01 ABO ADM ADSL ALDH2 BCKDHB BRAP C10orf118 C16orf93 CCNE1 CD164 CTNNB1 CTSW DCAF16 DYNC1I2 EIF5A ERP29 FAM108C1 FIBP GPN3 HAUS8 KRT8P33 LINC00461 LMOD1 MLLT10 MPHOSPH9 MSRA NMT1 NOV PDE1A PPTC7 PRSS53 RNF123 RP11-282O18.3 RP11-462G12.1 RPL39P5 SCMH1 SETD8 SF3A3 SH2B3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 USP36 VPS29
Comparative body size at age 10 1.75 12 4 8.9 0.30 3.4e-01 ADRA2B ADSL C16orf93 CERS5 CTSW MAP3K11 MSRA NME6 RP11-462G12.1 SIPA1 SRR U91328.21
Worry too long after embarrassment 1.46 2 2 4.4 0.00 1.0e+00 ARNTL MSRA
Wheeze or whistling in the chest in last year 1.61 4 2 4.4 0.98 1.6e-02 GMEB2 LIME1 RERE RNF123
Age at first live birth 1.66 2 1 2.2 0.00 1.0e+00 DCAF16 RNF123
Pulse wave peak to peak time 1.83 1 1 2.2 0.00 1.0e+00 ADAM1A
Health satisfaction 1.38 1 0 0.0 0.00 1.0e+00 LMOD1
Shortness of breath walking on level ground 1.08 2 0 0.0 0.00 1.0e+00 LMOD1 USP36
Qualifications: College or University degree 1.96 16 9 20.0 -0.85 6.6e-06 ABCB9 CCDC148 DCAF16 EDEM3 HAUS4 LIME1 LINC00461 LMOD1 MLLT10 MPHOSPH9 RNF123 RP11-261C10.5 RP11-282O18.3 SETD8 SLC5A11 SNX32
Medication for pain relief, constipation, heartburn 1.97 5 2 4.4 -0.94 1.9e-02 C20orf160 FAM108C1 MPHOSPH9 RP11-261C10.5 U91328.21
Medication: Blood pressure 5.88 32 18 40.0 0.97 4.7e-24 ACP2 ADAM1A ADRB1 ALDH2 ARHGAP42 ATP2B1 BRAP C1orf167 C20orf160 C4orf22 CLCN6 CMIP CTSW CYB5D1 DCAF16 ERP29 FAM108C1 FES FURIN LOC338758 LSP1 MANBA MPI MTHFR NME6 NOC3L SH2B3 TH1L TNNI2 TNNT3 WNT2B ZNF831
Angina (self-reported) 1.84 3 2 4.4 0.00 1.0e+00 ADAMTS7 FES FURIN
Migraine (self-reported) 1.40 2 0 0.0 0.00 1.0e+00 NT5C2 SLC24A3
Medication: Allopurinol 1.41 1 0 0.0 0.00 1.0e+00 CYB5D1
Mean time to correctly identify matches 1.84 6 5 11.1 0.98 3.7e-04 ADAM1A ALDH2 BRAP ERP29 NAA25 SH2B3
Heart disease (mother) 1.85 1 0 0.0 0.00 1.0e+00 ALDH2
Whole body fat mass 2.66 34 23 51.1 0.79 8.2e-09 ANKFY1 ARNTL C16orf93 C17orf81 CCDC148 CCNE1 CTNNB1 CTSW DYNC1I2 EDEM3 EIF5A EVX1 FIBP GPN3 LIME1 LINC00461 LMOD1 LOC100129961 MLLT10 MSRA NCF1 PITPNM2 PPTC7 PRSS53 RERE RNF123 RP11-462G12.1 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 STXBP5 USP36
Leg fat mass (right) 2.91 35 21 46.7 0.78 1.0e-08 ADSL ARNTL C16orf93 C17orf81 C8orf38 CCNE1 CTNNB1 CTSW DYNC1I2 EDEM3 EIF5A FIBP GPN3 IFT57 LIME1 LINC00461 LMOD1 LOC100129961 MLLT10 MSRA NCF1 PITPNM2 PPTC7 PRSS53 RERE RNF123 RP11-462G12.1 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 STXBP5 USP36 VPS29
Arm predicted mass (right) 2.57 44 34 75.6 0.07 6.6e-01 ABO ADM ADSL ALDH2 BCKDHB BRAP C10orf118 C16orf93 CCNE1 CD164 CMIP CTNNB1 DCAF16 DYNC1I2 EIF5A ERP29 FAM108C1 FIBP GPN3 KRT8P33 LINC00461 LMOD1 MLLT10 MPHOSPH9 MSRA NMT1 NOV PDE1A PPTC7 PRSS53 RNF123 RP11-282O18.3 RP11-462G12.1 SCMH1 SETD8 SF3A3 SH2B3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 USP36 VPS29
Pulse rate, automated reading 4.96 23 13 28.9 0.82 2.8e-07 ABO AC005517.3 ACHE ACP2 ADRA2B C16orf93 CASP7 CEP85L CSTA CTNNB1 GIGYF1 GPN3 KRT8P33 LINC00461 LMOD1 LOC100129961 MSTN PPTC7 RNF123 STAG3 STAG3L1 TRIP6 ZKSCAN1
Alcohol intake frequency. 1.53 7 3 6.7 0.99 5.5e-06 ABCB9 C16orf93 MPHOSPH9 PRSS53 RNF123 RP11-282O18.3 SETD8
Comparative height size at age 10 1.92 22 16 35.6 -0.51 1.0e-02 ABCB9 ALDH2 BCKDHB BRAP CEP152 CTNNB1 DCAF16 ERP29 FAM108C1 IGFBP3 MN1 MPHOSPH9 NOV RP11-282O18.3 RP11-462G12.1 SCMH1 SETD8 SH2B3 SLC25A37 SLC9A3R2 U91328.21 USP36
Number of full sisters 1.06 1 0 0.0 0.00 1.0e+00 NRBF2
Suffer from 'nerves' 1.17 2 0 0.0 0.00 1.0e+00 MSRA RERE
Overall health rating 2.24 12 8 17.8 0.97 8.0e-09 C11orf67 CCNE1 CTSW LMOD1 MLLT10 MSRA NCF1 PRSS53 RNF123 RP11-261C10.5 SLC5A11 SNX32
Chest pain or discomfort 1.33 1 0 0.0 0.00 1.0e+00 USP36
Age at last live birth 1.47 1 1 2.2 0.00 1.0e+00 RNF123
Leg pain on walking 1.40 1 1 2.2 0.00 1.0e+00 RNF123
Qualifications: NVQ or HND or HNC or equivalent 1.75 2 0 0.0 0.00 1.0e+00 JMJD7-PLA2G4B RNF123
Medication: Aspirin 2.20 1 1 2.2 0.00 1.0e+00 FES
Knee pain experienced in last month 1.46 2 0 0.0 0.00 1.0e+00 PRSS53 RP11-261C10.5
Hypertension (Self-reported) 8.69 81 56 124.4 0.97 2.0e-55 ABO ACP2 ADAM1A ADM ADRB1 AGT ALDH2 ARHGAP42 ARNTL ATP2B1 BRAP C10orf118 C16orf93 C1GALT1 C1orf167 C20orf160 C4orf22 CACNB2 CCDC148 CCNE1 CERS5 CHP1 CLCN6 CMIP CTSW CYB5D1 DCAF16 EDEM3 ERP29 EVX1 EXD1 FAM108C1 FES FURIN GMEB2 HAUS8 INO80 IRAK1BP1 ITGB5 LIME1 LOC338758 LSP1 MANBA MAP3K11 MLLT10 MPI MSRA MTHFR NAA25 NCF1 NEIL2 NME6 NMT1 NOC3L NRBF2 NSUN6 NT5C2 PDE1A PPTC7 PRSS53 RERE RP11-261C10.5 RP11-436D10.3 RPAP1 RSRC1 SH2B3 SIPA1 SLC25A37 SLC5A11 SNX32 SRR STAG3 STAG3L1 SWAP70 TCEA2 TH1L TNNI2 TNNT3 WNT2B ZKSCAN1 ZNF831
Illnesses of father: Heart disease 2.28 4 3 6.7 0.98 1.7e-02 ABO ADAMTS7 CDH13 FES
Smoking status: Previous 1.83 5 1 2.2 0.97 4.8e-03 ADAM1A ALDH2 BRAP ERP29 SH2B3
Forced expiratory volume in 1-second (FEV1), predicted 1.50 2 1 2.2 0.00 1.0e+00 DCAF16 DYNC1I2
Whole body fat-free mass 2.40 47 35 77.8 0.01 9.7e-01 ABCB9 ADM ADSL ALDH2 BCKDHB BRAP C10orf118 C16orf93 CCNE1 CD164 CPEB4 CTNNB1 DCAF16 DYNC1I2 EIF5A ERP29 FAM108C1 FIBP GPN3 HAUS8 KRT8P33 LINC00461 LMOD1 MPHOSPH9 MSRA NMT1 NOV NT5C2 PDE1A PPTC7 PRSS53 RNF123 RP11-282O18.3 RP11-436D10.3 RP11-462G12.1 SCMH1 SETD8 SF3A3 SH2B3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 ULK4 USP36 VPS29
Leg fat-free mass (right) 2.33 43 30 66.7 0.14 3.8e-01 ADM ADSL ALDH2 BCKDHB C10orf118 C16orf93 CCNE1 CD164 CPEB4 CTNNB1 DCAF16 DYNC1I2 FAM108C1 FES FURIN GPN3 HAUS8 KRT8P33 LINC00461 LMOD1 MPHOSPH9 MSRA NMT1 NOV NT5C2 PDE1A PPTC7 PRSS53 RNF123 RP11-282O18.3 RP11-436D10.3 RP11-462G12.1 SCMH1 SETD8 SF3A3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 ULK4 USP36 VPS29
Arm fat percentage (left) 2.58 32 23 51.1 0.84 8.0e-10 ABCB9 ABO ADM ARNTL C16orf93 C17orf81 CCDC148 CCNE1 CHP1 CTSW DCAF16 EDEM3 EVX1 EXD1 LINC00461 LMOD1 LOC100129961 MLLT10 MSRA NCF1 PITPNM2 PRSS53 RERE RNF123 RP11-462G12.1 RPAP1 SLC25A37 SLC5A11 SNX32 SRR STAG3L1 STXBP5
Average weekly red wine intake 1.72 4 1 2.2 -0.95 5.0e-02 ABCB9 MPI RP11-282O18.3 SETD8
Mood swings 1.63 5 2 4.4 0.52 3.7e-01 ACP2 C11orf67 MSRA RNF123 SLC5A11
Long-standing illness, disability or infirmity 1.95 1 0 0.0 0.00 1.0e+00 CHP1
Ever had bowel cancer screening 1.14 1 0 0.0 0.00 1.0e+00 RNF123
Diabetes diagnosed by doctor 1.98 3 0 0.0 0.00 1.0e+00 CTSW MPHOSPH9 RNF123
Qualifications: nursing, teaching 1.80 5 2 4.4 -1.00 3.4e-04 LMOD1 MPHOSPH9 PKHD1 RNF123 RP11-282O18.3
Eye problems/disorders: Cataract 1.05 1 1 2.2 0.00 1.0e+00 SLC24A3
Mouth/teeth dental problems: Mouth ulcers 1.23 1 0 0.0 0.00 1.0e+00 PREX1
Medication for cholesterol 3.90 11 4 8.9 -0.95 9.9e-06 ALDH2 ARHGAP42 C4orf22 EVX1 FES HAUS8 LSP1 SH2B3 TNNT3 WNT2B ZNF831
Mineral and other dietary supplements 1.51 3 0 0.0 0.00 1.0e+00 NMT1 NRBF2 REEP3
Asthma (self-reported) 1.58 4 1 2.2 0.64 3.6e-01 LIME1 RERE RP5-1029K10.2 U91328.21
Medication: Aspirin 2.17 1 1 2.2 0.00 1.0e+00 FES
Illnesses of father: None of the above (group 1) 2.47 2 1 2.2 0.00 1.0e+00 FES SH2B3
Smoking status: Current 1.64 1 0 0.0 0.00 1.0e+00 MSRA
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.75 6 3 6.7 0.33 5.3e-01 JAG1 LIME1 NRBF2 PRSS53 THSD4 U91328.21
Whole body water mass 2.41 47 37 82.2 0.00 9.9e-01 ABCB9 ADM ADSL ALDH2 BCKDHB BRAP C10orf118 C16orf93 CCNE1 CD164 CTNNB1 DCAF16 DYNC1I2 EIF5A ERP29 FAM108C1 FIBP GPN3 HAUS8 KRT8P33 LINC00461 LMOD1 MPHOSPH9 MSRA NMT1 NOV NT5C2 PDE1A PPTC7 PRSS53 RNF123 RP11-282O18.3 RP11-436D10.3 RP11-462G12.1 RPL39P5 SCMH1 SETD8 SF3A3 SH2B3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 ULK4 USP36 VPS29
Leg predicted mass (right) 2.33 43 30 66.7 0.14 3.8e-01 ADM ADSL ALDH2 BCKDHB C10orf118 C16orf93 CCNE1 CD164 CPEB4 CTNNB1 DCAF16 DYNC1I2 FAM108C1 FES FURIN GPN3 HAUS8 KRT8P33 LINC00461 LMOD1 MPHOSPH9 MSRA NMT1 NOV NT5C2 PDE1A PPTC7 PRSS53 RNF123 RP11-282O18.3 RP11-436D10.3 RP11-462G12.1 SCMH1 SETD8 SF3A3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 ULK4 USP36 VPS29
Arm fat mass (left) 2.62 33 19 42.2 0.84 4.4e-10 ADSL ARNTL C16orf93 C17orf81 CCNE1 CTNNB1 CTSW DYNC1I2 EIF5A FIBP GPN3 IFT57 LIME1 LINC00461 LMOD1 LOC100129961 MLLT10 MSRA NCF1 PITPNM2 PPTC7 PRSS53 RERE RNF123 RP11-462G12.1 SLC25A37 SLC5A11 SLC9A3R2 SNX32 SRR STAG3L1 STXBP5 USP36
Number of self-reported non-cancer illnesses 3.35 13 3 6.7 0.95 6.4e-08 ALDH2 BRAP CCNE1 CLCN6 CYB5D1 ERP29 GMEB2 HAUS8 LIME1 MLLT10 RP5-1029K10.2 SH2B3 ZNF831
Miserableness 1.66 5 2 4.4 -0.34 5.8e-01 ACP2 MSRA RERE RNF123 RP11-261C10.5
Guilty feelings 1.36 2 0 0.0 0.00 1.0e+00 ARNTL MSRA
Financial situation satisfaction 1.03 1 0 0.0 0.00 1.0e+00 RNF123
Medication: Blood pressure 6.64 40 26 57.8 0.95 2.7e-24 ACP2 ADM ADRB1 AGT ALDH2 ARHGAP42 BRAP C1GALT1 C4orf22 CACNB2 CERS5 CHP1 CLCN6 CMIP CTSW CYB5D1 ERP29 EVX1 EXD1 FAM108C1 FES FURIN GMEB2 HAUS8 LIME1 LSP1 MAP3K11 MPI MSRA MTHFR NME6 NRBF2 NT5C2 RP11-436D10.3 SH2B3 SIPA1 TNNI2 TNNT3 WNT2B ZNF831
High cholesterol (Self-reported) 1.98 4 1 2.2 0.59 4.1e-01 ABO ARHGAP42 DCAF16 MPHOSPH9
Medication: Bendroflumethiazide 4.64 19 8 17.8 0.94 4.4e-09 ACP2 ADAMTS7 ADRB1 AGT ARHGAP42 ATP2B1 C16orf93 CACNB2 CCNE1 EVX1 FES LSP1 MPI MSRA RP11-436D10.3 TNNI2 TNNT3 WNT2B ZNF831
Medication: Paracetamol 1.56 3 0 0.0 0.00 1.0e+00 MLLT10 RP11-261C10.5 U91328.21
Medication: Lisinopril 2.95 5 0 0.0 0.96 9.7e-03 ARHGAP42 LSP1 NME6 NRBF2 ZNF831
Medication: Atorvastatin 1.89 1 0 0.0 0.00 1.0e+00 ABO
Illnesses of father: High blood pressure 2.95 2 1 2.2 0.00 1.0e+00 C4orf22 FES
Ever smoked 1.71 1 1 2.2 0.00 1.0e+00 SRR
Basal metabolic rate 2.44 45 35 77.8 0.11 4.6e-01 ADM ADSL ALDH2 BCKDHB BRAP C10orf118 C16orf93 CCNE1 CD164 CPEB4 CTNNB1 CTSW DCAF16 DYNC1I2 EIF5A ERP29 FAM108C1 FIBP GPN3 KRT8P33 LINC00461 LMOD1 MLLT10 MPHOSPH9 MSRA NMT1 NOV PDE1A PPTC7 PRSS53 RNF123 RP11-282O18.3 RP11-436D10.3 RP11-462G12.1 SCMH1 SETD8 SF3A3 SH2B3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 USP36 VPS29
Leg fat percentage (left) 2.98 37 19 42.2 0.79 1.6e-09 ABCB9 ADM ARNTL C17orf81 C8orf38 CCDC148 CCNE1 CHP1 CLCN6 CTSW DCAF16 EDEM3 EXD1 FIBP GPN3 LIME1 LINC00461 LMOD1 LOC100129961 MLLT10 MPHOSPH9 MSRA NCF1 NMT1 PITPNM2 PPTC7 PRSS53 REEP3 RERE RNF123 RP11-462G12.1 RPAP1 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1
Arm fat-free mass (left) 2.57 46 31 68.9 0.08 5.8e-01 ABO ADM ADSL ALDH2 BCKDHB BRAP C10orf118 C16orf93 CCNE1 CD164 CTNNB1 CTSW DCAF16 DYNC1I2 EIF5A ERP29 FAM108C1 FIBP GPN3 KRT8P33 LIME1 LINC00461 LMOD1 MLLT10 MPHOSPH9 MSRA NMT1 NOV PDE1A PPTC7 PRSS53 RNF123 RP11-282O18.3 RP11-462G12.1 RPL39P5 SCMH1 SETD8 SF3A3 SH2B3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 USP36 VPS29
Number of operations (self-reported) 1.43 1 0 0.0 0.00 1.0e+00 MLLT10
Average weekly beer plus cider intake 1.27 1 0 0.0 0.00 1.0e+00 RNF123
Irritability 1.38 2 2 4.4 0.00 1.0e+00 LINC00461 MSRA
Risk taking 1.40 2 0 0.0 0.00 1.0e+00 MSRA RP11-261C10.5
Age started oral contraceptive pill 1.26 1 0 0.0 0.00 1.0e+00 RNF123
Unable to work because of sickness or disability 1.17 1 0 0.0 0.00 1.0e+00 SLC5A11
Myopia 1.25 1 0 0.0 0.00 1.0e+00 WNT2B
Vascular/heart problems diagnosed by doctor 8.52 79 54 120.0 -0.97 2.5e-58 ABO ACP2 ADAM1A ADRB1 AGT ALDH2 ARHGAP42 ARNTL ATP2B1 BRAP C10orf118 C16orf93 C1GALT1 C1orf167 C20orf160 C4orf22 C8orf38 CACNB2 CCDC148 CERS5 CHP1 CLCN6 CMIP CTSW CYB5D1 DCAF16 EDEM3 ERP29 EVX1 EXD1 FAM108C1 FES FURIN GMEB2 HAUS8 HYI INO80 IRAK1BP1 ITGB5 LIME1 LMOD1 LOC338758 LSP1 MANBA MAP3K11 MLLT10 MPI MSRA MTHFR NAA25 NCF1 NEIL2 NME6 NOC3L NRBF2 NSUN6 NT5C2 PDE1A PRSS53 RERE RP11-261C10.5 RP11-436D10.3 RP5-1029K10.2 RPAP1 RSRC1 RYK SH2B3 SIPA1 SLC5A11 SNX32 STAG3L1 SWAP70 TCEA2 TH1L TNNI2 TNNT3 WNT2B ZKSCAN1 ZNF831
Cholesterol lowering medication 1.92 3 1 2.2 0.00 1.0e+00 ABO DCAF16 PRSS53
Pain experienced in last month 1.64 2 0 0.0 0.00 1.0e+00 ALDH2 RNF123
Heart attack/myocardial infarction (self-reported) 2.03 2 1 2.2 0.00 1.0e+00 FES SH2B3
Deep venous thrombosis (DVT) (self-reported) 3.15 1 1 2.2 0.00 1.0e+00 ABO
Heart disease (siblings) 1.82 1 0 0.0 0.00 1.0e+00 FES
Pack years of smoking 1.54 2 1 2.2 0.00 1.0e+00 ADAMTS7 PPTC7
Impedance of whole body 2.08 32 23 51.1 -0.27 1.2e-01 ABO ADAMTS8 ADM ADSL C4orf3 CCNE1 CERS5 CTSW FAM108C1 FIBP GNAO1 HAUS8 KRT8P33 KTN1-AS1 LINC00461 LMOD1 MANBA MSRA NCF1 NMT1 NOC3L NT5C2 PDE1A PRSS53 RNF123 RP11-23P13.4 RP11-462G12.1 RP5-1029K10.2 SNX32 STAG3L1 SWAP70 VPS29
Leg fat mass (left) 2.94 35 24 53.3 0.76 3.9e-08 ADSL ARNTL C16orf93 C17orf81 C8orf38 CCNE1 CTSW DYNC1I2 EDEM3 EIF5A FAM108C1 FIBP GPN3 IFT57 LIME1 LINC00461 LMOD1 LOC100129961 MLLT10 MSRA NCF1 PITPNM2 PPTC7 PRSS53 RERE RNF123 RP11-462G12.1 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 STXBP5 USP36 VPS29
Arm predicted mass (left) 2.58 44 31 68.9 0.09 5.3e-01 ABO ADM ADSL ALDH2 BCKDHB BRAP C10orf118 C16orf93 CCNE1 CD164 CMIP CTNNB1 DCAF16 DYNC1I2 EIF5A ERP29 FAM108C1 FIBP GPN3 KRT8P33 LINC00461 LMOD1 MLLT10 MPHOSPH9 MSRA NMT1 NOV PDE1A PPTC7 PRSS53 RNF123 RP11-282O18.3 RP11-462G12.1 RPL39P5 SCMH1 SF3A3 SH2B3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 STAG3L1 USP36 VPS29

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 49 1.40 3.2
GTEx Adipose Visceral Omentum 36 1.77 3.5
GTEx Adrenal Gland 22 1.51 3.0
GTEx Artery Aorta 49 1.65 3.6
GTEx Artery Coronary 18 1.52 3.4
GTEx Artery Tibial 68 1.81 3.5
GTEx Brain Caudate basal ganglia 12 1.30 3.4
GTEx Brain Cerebellar Hemisphere 22 1.48 3.2
GTEx Brain Cerebellum 28 1.41 3.4
GTEx Brain Cortex 19 1.84 3.3
GTEx Brain Frontal Cortex BA9 17 1.84 3.5
GTEx Brain Hippocampus 2 0.38 3.1
GTEx Brain Hypothalamus 6 1.02 3.1
GTEx Brain Nucleus accumbens basal ganglia 12 1.39 3.2
GTEx Brain Putamen basal ganglia 9 1.44 3.3
GTEx Breast Mammary Tissue 35 1.77 3.3
GTEx Breast Mammary Tissue (Male) 21 1.76 3.2
GTEx Breast Mammary Tissue (Female) 20 1.22 3.2
GTEx Cells EBV-transformed lymphocytes 18 1.26 3.3
GTEx Cells Transformed fibroblasts 57 1.36 3.2
GTEx Colon Sigmoid 23 1.57 3.3
GTEx Colon Transverse 33 1.60 3.2
GTEx Esophagus Gastroesophageal Junction 25 1.73 3.4
GTEx Esophagus Mucosa 53 1.60 3.2
GTEx Esophagus Muscularis 47 1.45 3.2
GTEx Heart Atrial Appendage 19 1.20 3.2
GTEx Heart Left Ventricle 26 1.70 3.3
GTEx Liver 13 1.81 3.0
GTEx Lung 46 1.60 3.3
GTEx Muscle Skeletal 40 1.38 3.2
GTEx Nerve Tibial 67 1.55 3.2
GTEx Ovary 18 1.98 3.6
GTEx Pancreas 30 1.84 3.5
GTEx Pituitary 16 1.43 3.3
GTEx Prostate 15 1.80 3.7
GTEx Skin Not Sun Exposed Suprapubic 40 1.63 3.4
GTEx Skin Sun Exposed Lower leg 55 1.51 3.3
GTEx Small Intestine Terminal Ileum 8 1.74 3.5
GTEx Spleen 13 0.92 3.2
GTEx Stomach 22 1.51 3.5
GTEx Testis 41 1.30 3.2
GTEx Thyroid 54 1.35 3.2
GTEx Uterus 6 1.06 3.1
GTEx Vagina 10 1.57 3.4
GTEx Whole Blood 28 1.40 3.2
METSIM Adipose 36 0.78 2.8
NTR Blood 21 0.87 2.9
ROSMAP Brain Pre-frontal Cortex 74 1.69 3.1
YFS Blood 49 1.06 2.8
CommonMind Brain Pre-frontal Cortex 62 1.15 2.9
The Cancer Genome Atlas Bladder Urothelial Carcinoma 28 1.69 3.2
The Cancer Genome Atlas Breast Invasive Carcinoma 56 1.27 2.9
The Cancer Genome Atlas Cervical Squamous Cell Carcinoma 10 0.91 3.0
The Cancer Genome Atlas Colon Adenocarcinoma 29 1.40 3.2
The Cancer Genome Atlas Esophageal Carcinoma 8 1.17 2.9
The Cancer Genome Atlas Glioblastoma Multiforme 8 0.78 2.8
The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma 35 1.29 3.0
The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma 51 1.24 2.9
The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma 32 1.56 3.0
The Cancer Genome Atlas Brain Lower Grade Glioma 41 0.95 2.8
The Cancer Genome Atlas Liver Hepatocellular Carcinoma 11 0.99 2.8
The Cancer Genome Atlas Lung Adenocarcinoma 46 1.57 3.0
The Cancer Genome Atlas Lung Squamous Cell Carcinoma 27 1.08 2.8
The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma 19 1.19 2.9
The Cancer Genome Atlas Pancreatic Adenocarcinoma 26 1.57 3.2
The Cancer Genome Atlas Pheochromocytoma and Paraganglioma 21 1.58 3.1
The Cancer Genome Atlas Prostate Adenocarcinoma 50 1.08 2.8
The Cancer Genome Atlas Rectum Adenocarcinoma 8 1.16 3.1
The Cancer Genome Atlas Soft Tissue Sarcoma 9 0.84 2.6
The Cancer Genome Atlas Skin Cutaneous Melanoma 7 1.31 3.0
The Cancer Genome Atlas Stomach Adenocarcinoma 21 1.25 3.0
The Cancer Genome Atlas Testicular Germ Cell Tumors 14 1.09 3.0
The Cancer Genome Atlas Thyroid Carcinoma 51 0.99 2.8
The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma 3 0.59 2.9