Best TWAS P=1.71e-09 · Best GWAS P=4.6e-08 conditioned to 0.083
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | SNTB2 | 0.12 | 0.01 | enet | 20 | 0.00 | 4.9e-01 | -5.4 | 6.0 | 1.7e-09 | -0.70 | 0.01 | 0.91 | TRUE |
| 5 | GTEx | Skin Sun Exposed Lower leg | SNTB2 | 0.10 | 0.09 | lasso | 6 | 0.07 | 9.7e-07 | -5.4 | 5.5 | 3.9e-08 | -0.99 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Esophagus Mucosa | SNTB2 | 0.09 | 0.06 | lasso | 2 | 0.04 | 1.0e-03 | -5.3 | 5.3 | 1.2e-07 | -0.93 | 0.01 | 0.98 | FALSE |
| 4 | GTEx | Lung | SNTB2 | 0.08 | 0.05 | enet | 12 | 0.04 | 2.8e-04 | -5.5 | 5.3 | 1.3e-07 | -0.86 | 0.02 | 0.96 | FALSE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SNTB2 | 0.02 | 0.02 | lasso | 3 | 0.01 | 1.0e-03 | -5.4 | 5.3 | 1.3e-07 | -0.97 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | NIP7 | 0.06 | 0.06 | lasso | 2 | 0.06 | 5.3e-05 | -5.4 | 5.3 | 1.5e-07 | -0.97 | 0.01 | 0.98 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | SNTB2 | 0.05 | 0.01 | blup | 41 | 0.04 | 6.9e-05 | 2.5 | 5.2 | 2.5e-07 | -0.88 | 0.02 | 0.91 | FALSE |