Best TWAS P=9.56e-08 · Best GWAS P=3.68e-07 conditioned to 0.164
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | TRIM59 | 0.03 | 0.01 | blup | 379 | 0.01 | 0.03130 | 4.8 | -5.2 | 1.7e-07 | -0.86 | 0.04 | 0.92 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TRIM59 | 0.01 | 0.01 | blup | 41 | 0.01 | 0.00078 | -4.2 | -5.1 | 2.9e-07 | -0.77 | 0.05 | 0.58 | FALSE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | IFT80 | 0.03 | 0.02 | blup | 94 | 0.02 | 0.00313 | -4.1 | -5.3 | 9.6e-08 | -0.80 | 0.08 | 0.71 | TRUE |