Best TWAS P=5.49e-08 · Best GWAS P=6.36e-07 conditioned to 0.439
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue | RSRC1 | 0.14 | 0.10 | lasso | 6 | 0.13 | 4.9e-07 | 4.5 | -5.4 | 7.4e-08 | -0.74 | 0.02 | 0.95 | FALSE |
2 | GTEx | Esophagus Mucosa | RP11-538P18.2 | 0.12 | 0.10 | lasso | 5 | 0.14 | 1.9e-09 | 4.5 | -5.2 | 1.8e-07 | -0.69 | 0.05 | 0.90 | FALSE |
3 | YFS | Blood | RSRC1 | 0.13 | 0.13 | enet | 26 | 0.17 | 8.8e-54 | 4.7 | -5.4 | 5.5e-08 | -0.84 | 0.02 | 0.97 | TRUE |