Best TWAS P=7.34e-10 · Best GWAS P=1.38e-08 conditioned to 0.0798
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | DCAF16 | 0.10 | 0.01 | enet | 6 | 0.02 | 4.7e-02 | 4.7 | -5.9 | 4.4e-09 | 0.61 | 0.12 | 0.50 | FALSE |
| 2 | GTEx | Breast Mammary Tissue | DCAF16 | 0.12 | 0.08 | lasso | 4 | 0.10 | 6.4e-06 | -4.7 | -5.5 | 5.2e-08 | 0.71 | 0.13 | 0.68 | FALSE |
| 3 | GTEx | Spleen | DCAF16 | 0.35 | 0.02 | lasso | 5 | 0.11 | 8.5e-04 | -4.6 | -5.5 | 4.1e-08 | 0.74 | 0.04 | 0.69 | FALSE |
| 4 | GTEx | Thyroid | DCAF16 | 0.11 | 0.02 | lasso | 5 | 0.03 | 2.3e-03 | -4.6 | -5.7 | 1.5e-08 | 0.79 | 0.05 | 0.92 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DCAF16 | 0.09 | 0.02 | lasso | 3 | 0.04 | 5.2e-05 | -4.5 | -5.7 | 1.1e-08 | 0.72 | 0.22 | 0.43 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DCAF16 | 0.04 | 0.04 | blup | 31 | 0.04 | 2.2e-05 | -4.6 | -6.2 | 7.3e-10 | 0.73 | 0.18 | 0.48 | TRUE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | DCAF16 | 0.07 | 0.04 | blup | 31 | 0.07 | 4.9e-07 | -4.4 | -5.3 | 1.1e-07 | 0.68 | 0.27 | 0.57 | FALSE |