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chr4:47,802,595-53,472,171

Best TWAS P=8.79e-13 · Best GWAS P=5.09e-13 conditioned to 0.105

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adrenal Gland	OCIAD1	0.10	-0.01	enet	11	0.02	5.5e-02	-6.1	-6.6	3.4e-11	-0.84	0.05	0.67	FALSE
2	GTEx	Artery Aorta	OCIAD1	0.09	0.10	lasso	4	0.10	2.4e-06	6.9	-6.8	1.3e-11	-0.92	0.07	0.93	FALSE
3	GTEx	Artery Tibial	OCIAD1	0.09	0.12	enet	6	0.11	1.1e-08	7.0	-6.8	8.2e-12	-0.91	0.08	0.92	FALSE
4	GTEx	Brain Cerebellum	OCIAD1	0.10	0.04	lasso	5	0.02	1.1e-01	6.9	-6.3	2.6e-10	-0.83	0.06	0.44	FALSE
5	GTEx	Breast Mammary Tissue	DCUN1D4	0.08	0.02	enet	11	0.04	2.4e-03	4.8	5.2	2.3e-07	0.40	0.05	0.87	FALSE
6	GTEx	Colon Sigmoid	OCIAD1	0.08	0.04	lasso	8	0.02	8.6e-02	7.1	-6.5	6.0e-11	-0.87	0.06	0.70	FALSE
7	GTEx	Colon Transverse	OCIAD1	0.07	0.07	lasso	5	0.05	2.8e-03	7.0	-6.9	5.2e-12	-0.91	0.07	0.87	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	OCIAD2	0.07	0.01	lasso	4	0.02	8.3e-02	-5.5	-5.3	1.2e-07	-0.74	0.06	0.58	FALSE
9	GTEx	Esophagus Mucosa	OCIAD1	0.07	0.06	lasso	4	0.06	9.9e-05	6.8	-7.1	1.4e-12	-0.95	0.08	0.92	FALSE
10	GTEx	Esophagus Mucosa	OCIAD1-AS1	0.11	0.01	lasso	7	0.01	1.2e-01	-5.6	5.6	1.8e-08	0.54	0.07	0.30	FALSE
11	GTEx	Esophagus Muscularis	OCIAD1	0.12	0.16	lasso	6	0.17	9.1e-11	7.0	-7.2	8.8e-13	-0.92	0.09	0.91	TRUE
12	GTEx	Nerve Tibial	OCIAD1	0.14	0.04	enet	25	0.03	3.7e-03	7.2	-5.4	7.1e-08	-0.79	0.05	0.94	FALSE
13	GTEx	Ovary	FRYL	0.12	-0.01	enet	21	0.03	7.2e-02	7.1	7.1	9.6e-13	0.96	0.05	0.63	FALSE
14	GTEx	Skin Sun Exposed Lower leg	FRYL	0.05	0.01	enet	19	0.02	8.6e-03	-5.7	5.8	6.5e-09	0.69	0.13	0.64	FALSE
15	GTEx	Testis	OCIAD2	0.19	0.09	lasso	3	0.10	3.2e-05	-5.6	5.7	1.5e-08	0.56	0.21	0.22	FALSE
16	NTR	Blood	OCIAD1	0.01	0.01	bslmm	207	0.00	1.8e-02	6.9	-6.8	8.3e-12	-0.86	0.08	0.90	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	OCIAD1	0.06	0.07	enet	13	0.07	3.8e-09	7.0	-6.1	1.0e-09	-0.79	0.08	0.92	FALSE
18	YFS	Blood	OCIAD2	0.05	0.05	lasso	5	0.04	1.8e-14	-5.7	5.9	3.8e-09	0.60	0.98	0.02	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	OCIAD1	0.05	0.03	enet	8	0.04	1.0e-05	7.0	-6.0	1.4e-09	-0.77	0.02	0.92	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	SLC10A4	0.05	0.07	blup	36	0.07	6.0e-08	7.0	6.7	1.8e-11	0.87	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SLC10A4	0.05	0.02	blup	36	0.03	6.3e-03	-5.4	6.3	2.8e-10	0.86	0.03	0.55	FALSE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	FRYL	0.03	0.03	enet	8	0.03	3.2e-04	7.0	7.0	2.8e-12	0.89	0.05	0.82	FALSE
23	The Cancer Genome Atlas	Testicular Germ Cell Tumors	SLC10A4	0.09	0.04	lasso	4	0.05	7.5e-03	7.1	7.1	1.6e-12	0.94	0.01	0.88	FALSE
24	The Cancer Genome Atlas	Thyroid Carcinoma	FRYL	0.02	0.01	blup	93	0.01	3.6e-02	7.0	7.1	1.6e-12	0.97	0.04	0.71	FALSE