Best TWAS P=1.03e-21 · Best GWAS P=8.51e-30 conditioned to 1.05e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | RP11-981P6.1 | 0.33 | 0.29 | lasso | 3 | 0.19 | 2.2e-07 | -5.0 | -5.7 | 1.2e-08 | 0.53 | 0.99 | 0.00 | FALSE |
| 2 | GTEx | Artery Tibial | ATP2B1 | 0.08 | 0.01 | enet | 10 | 0.03 | 3.5e-03 | -11.2 | -9.6 | 1.0e-21 | 0.87 | 0.01 | 0.97 | TRUE |
| 3 | GTEx | Colon Sigmoid | RP11-981P6.1 | 0.19 | 0.12 | lasso | 4 | 0.11 | 9.7e-05 | -5.0 | -5.4 | 5.4e-08 | 0.58 | 0.31 | 0.11 | FALSE |
| 4 | GTEx | Lung | RP11-981P6.1 | 0.08 | 0.01 | lasso | 3 | 0.01 | 3.9e-02 | -5.0 | -6.1 | 9.9e-10 | 0.60 | 0.23 | 0.32 | FALSE |
| 5 | GTEx | Prostate | POC1B | 0.25 | 0.00 | enet | 37 | 0.01 | 1.6e-01 | -9.7 | 6.2 | 7.8e-10 | -0.50 | 0.02 | 0.64 | FALSE |
| 6 | GTEx | Spleen | RP11-981P6.1 | 0.28 | 0.18 | lasso | 13 | 0.14 | 2.1e-04 | -4.9 | -5.2 | 2.6e-07 | 0.60 | 0.19 | 0.56 | FALSE |
| 7 | GTEx | Thyroid | RP11-981P6.1 | 0.24 | 0.25 | lasso | 5 | 0.26 | 3.9e-20 | -5.0 | -5.5 | 3.4e-08 | 0.63 | 1.00 | 0.00 | FALSE |
| 8 | METSIM | Adipose | POC1B | 0.07 | 0.03 | bslmm | 381 | 0.03 | 5.2e-05 | -5.0 | 6.5 | 7.1e-11 | -0.55 | 0.90 | 0.03 | FALSE |