[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (left) : ← →

chr6:44,079,216-46,043,561

Best TWAS P=4.35e-19 · Best GWAS P=8.11e-26 conditioned to 1.9e-12

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Visceral Omentum	SUPT3H	0.27	0.10	lasso	7	0.06	3.4e-04	6.7	-8.2	2.3e-16	0.42	0.96	0.02	FALSE
2	GTEx	Artery Tibial	SUPT3H	0.13	0.01	enet	21	0.02	1.9e-02	-7.0	-7.5	6.5e-14	0.60	0.02	0.96	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	SUPT3H	0.20	0.08	lasso	6	0.10	3.0e-04	7.0	-5.7	1.1e-08	0.09	0.42	0.03	FALSE
4	GTEx	Cells Transformed fibroblasts	SUPT3H	0.15	0.10	lasso	4	0.13	8.8e-10	6.9	-5.9	4.0e-09	0.04	1.00	0.00	FALSE
5	GTEx	Esophagus Gastroesophageal Junction	SUPT3H	0.27	0.01	lasso	3	0.00	2.7e-01	-7.0	-7.5	4.3e-14	0.40	0.10	0.25	FALSE
6	GTEx	Esophagus Mucosa	SUPT3H	0.08	0.09	lasso	3	0.08	6.4e-06	6.7	-7.5	8.4e-14	0.29	0.84	0.05	FALSE
7	GTEx	Esophagus Muscularis	SUPT3H	0.10	0.03	enet	20	0.02	1.3e-02	-7.0	-5.7	9.4e-09	0.36	0.13	0.45	FALSE
8	GTEx	Lung	SUPT3H	0.10	0.06	enet	21	0.03	1.3e-03	6.9	-7.3	2.1e-13	0.24	0.84	0.02	FALSE
9	GTEx	Nerve Tibial	SUPT3H	0.17	0.12	lasso	5	0.10	2.2e-07	6.9	-6.9	4.9e-12	0.20	1.00	0.00	FALSE
10	GTEx	Pancreas	SUPT3H	0.11	0.07	lasso	2	0.05	3.6e-03	6.8	-6.8	9.4e-12	0.18	0.36	0.05	FALSE
11	GTEx	Skin Sun Exposed Lower leg	SUPT3H	0.07	0.03	lasso	5	0.04	4.2e-04	6.9	-8.0	1.8e-15	0.35	0.47	0.07	FALSE
12	GTEx	Spleen	SUPT3H	0.32	0.06	enet	12	0.11	9.5e-04	6.2	-7.5	4.5e-14	0.23	0.26	0.29	FALSE
13	GTEx	Thyroid	SUPT3H	0.29	0.07	lasso	8	0.07	7.3e-06	-7.6	-7.0	2.6e-12	0.65	0.89	0.05	FALSE
14	METSIM	Adipose	SUPT3H	0.11	0.04	bslmm	657	0.06	2.7e-09	7.0	-6.1	1.0e-09	0.26	1.00	0.00	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	SUPT3H	0.02	0.01	blup	191	0.01	3.0e-03	6.7	-6.6	4.3e-11	0.18	0.86	0.00	FALSE
16	The Cancer Genome Atlas	Colon Adenocarcinoma	SUPT3H	0.08	0.01	blup	191	0.05	1.0e-03	6.9	-8.4	5.0e-17	0.37	0.28	0.08	FALSE
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SUPT3H	0.04	0.01	blup	191	0.02	6.5e-03	-1.3	-5.5	3.8e-08	0.15	0.67	0.01	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	SUPT3H	0.07	0.05	enet	12	0.08	1.1e-09	-1.7	-5.2	2.0e-07	0.03	1.00	0.00	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	SUPT3H	0.03	0.03	lasso	2	0.02	8.9e-04	6.9	-6.6	4.7e-11	0.19	0.30	0.08	FALSE
20	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SUPT3H	0.12	0.08	blup	191	0.09	2.8e-04	6.8	-8.1	5.4e-16	0.30	0.67	0.03	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	SUPT3H	0.06	0.04	lasso	4	0.05	2.1e-05	7.0	-8.9	4.3e-19	0.49	0.70	0.08	TRUE