[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (left) :

chr11:26,818,083-28,220,506

Best TWAS P=1.8e-13 · Best GWAS P=4.02e-26 conditioned to 6.52e-16

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta LIN7C 0.14 0.09 lasso 3 0.06 1.9e-04 5.7 -5.2 2.3e-07 -0.21 0.54 0.02 FALSE
2 GTEx Colon Transverse LIN7C 0.13 0.04 enet 19 0.08 1.4e-04 5.3 7.4 1.8e-13 0.46 0.15 0.22 TRUE
3 GTEx Esophagus Mucosa LIN7C 0.10 0.05 enet 14 0.04 1.1e-03 3.9 5.5 3.1e-08 0.19 0.93 0.02 FALSE
4 GTEx Skin Not Sun Exposed Suprapubic LIN7C 0.11 0.03 lasso 4 0.02 3.4e-02 5.3 5.4 7.4e-08 0.28 0.20 0.08 FALSE
5 ROSMAP Brain Pre-frontal Cortex LIN7C 0.10 0.09 lasso 2 0.07 8.1e-10 5.7 5.3 9.6e-08 0.16 1.00 0.00 FALSE
6 The Cancer Genome Atlas Brain Lower Grade Glioma LIN7C 0.09 0.12 lasso 2 0.12 2.6e-13 5.7 5.3 8.7e-08 0.14 0.00 1.00 FALSE
7 The Cancer Genome Atlas Thyroid Carcinoma LIN7C 0.09 0.10 enet 7 0.09 8.1e-09 5.7 5.9 4.6e-09 0.16 0.00 1.00 FALSE