Best TWAS P=3.33e-08 · Best GWAS P=4.08e-07 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adrenal Gland | MYLK4 | 0.38 | 0.28 | lasso | 2 | 0.27 | 3.0e-10 | -5.1 | -5.5 | 3.3e-08 | 0.96 | 0 | 1.00 | TRUE |
2 | GTEx | Esophagus Mucosa | MYLK4 | 0.27 | 0.26 | lasso | 2 | 0.29 | 1.1e-19 | -5.1 | -5.5 | 3.4e-08 | 0.96 | 0 | 1.00 | FALSE |
3 | GTEx | Heart Left Ventricle | MYLK4 | 0.30 | 0.14 | lasso | 6 | 0.14 | 6.9e-08 | -5.1 | -5.3 | 1.1e-07 | 0.98 | 0 | 1.00 | FALSE |
4 | GTEx | Nerve Tibial | MYLK4 | 0.35 | 0.28 | lasso | 5 | 0.30 | 2.6e-21 | -5.1 | -5.4 | 6.7e-08 | 0.98 | 0 | 1.00 | FALSE |
5 | GTEx | Skin Sun Exposed Lower leg | MYLK4 | 0.30 | 0.07 | lasso | 6 | 0.16 | 4.4e-13 | -5.1 | -5.2 | 1.7e-07 | 0.80 | 0 | 1.00 | FALSE |
6 | GTEx | Spleen | MYLK4 | 0.61 | 0.10 | lasso | 19 | 0.08 | 4.3e-03 | -5.1 | -5.3 | 1.1e-07 | 0.85 | 0 | 0.88 | FALSE |
7 | GTEx | Thyroid | MYLK4 | 0.45 | 0.29 | enet | 43 | 0.31 | 2.4e-24 | -5.1 | -5.2 | 2.0e-07 | 0.85 | 0 | 1.00 | FALSE |