Best TWAS P=1.23e-08 · Best GWAS P=2.23e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ARFGEF2 | 0.09 | 0.05 | lasso | 8 | 0.10 | 9.2e-13 | 5.6 | -5.3 | 1.4e-07 | -0.83 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Testis | ARFGEF2 | 0.20 | 0.20 | lasso | 7 | 0.24 | 5.4e-11 | 4.7 | -5.4 | 5.7e-08 | -0.93 | 0.02 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARFGEF2 | 0.05 | 0.04 | lasso | 5 | 0.05 | 3.2e-06 | 5.6 | -5.7 | 1.2e-08 | -0.95 | 0.00 | 1.00 | TRUE |