Best TWAS P=1.47e-07 · Best GWAS P=4e-07 conditioned to 0.45
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | CYP2D6 | 0.33 | 0.18 | lasso | 5 | 0.29 | 5.6e-18 | -5.1 | -5.3 | 1.5e-07 | 0.90 | 0.00 | 0.99 | TRUE |
| 2 | GTEx | Thyroid | SLC25A5P1 | 0.11 | 0.08 | enet | 13 | 0.07 | 3.2e-06 | -4.5 | 5.2 | 1.6e-07 | -0.85 | 0.03 | 0.93 | FALSE |