Best TWAS P=8.24e-08 · Best GWAS P=2.1e-06 conditioned to 0.777
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NDUFA2 | 0.02 | 0.01 | bslmm | 343 | 0.01 | 7.8e-03 | -4.5 | 5.2 | 2.1e-07 | -0.90 | 0.07 | 0.65 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | NDUFA2 | 0.09 | 0.12 | enet | 22 | 0.12 | 1.3e-15 | -4.2 | 5.2 | 1.9e-07 | -0.85 | 0.04 | 0.92 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | ZMAT2 | 0.03 | 0.02 | bslmm | 185 | 0.02 | 6.5e-04 | -4.2 | -5.4 | 8.2e-08 | 0.86 | 0.04 | 0.90 | TRUE |