Best TWAS P=1.14e-07 · Best GWAS P=3.04e-07 conditioned to 0.261
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | CYBRD1 | 0.20 | 0.07 | lasso | 2 | 0.14 | 4.5e-05 | -4.5 | 5.2 | 1.9e-07 | -0.78 | 0.05 | 0.43 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | CYBRD1 | 0.37 | 0.16 | lasso | 9 | 0.30 | 3.0e-39 | -4.4 | 5.2 | 1.8e-07 | -0.77 | 0.13 | 0.81 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | CYBRD1 | 0.10 | 0.06 | lasso | 4 | 0.06 | 6.2e-07 | -4.5 | 5.3 | 1.1e-07 | -0.86 | 0.01 | 0.99 | TRUE |