Best TWAS P=3.27e-08 · Best GWAS P=7.97e-09 conditioned to 7.73e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue (Female) | CEP192 | 0.34 | 0.23 | lasso | 11 | 0.26 | 2.4e-08 | 4.8 | 5.3 | 1.5e-07 | 0.17 | 0.21 | 0.77 | FALSE |
2 | GTEx | Cells EBV-transformed lymphocytes | CEP192 | 0.52 | 0.34 | lasso | 5 | 0.36 | 1.6e-12 | 4.6 | 5.5 | 3.3e-08 | 0.38 | 0.27 | 0.71 | TRUE |
3 | GTEx | Liver | CEP192 | 0.41 | 0.29 | lasso | 6 | 0.41 | 1.6e-12 | 4.8 | 5.2 | 2.3e-07 | 0.17 | 0.19 | 0.80 | FALSE |
4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | CEP192 | 0.09 | 0.07 | blup | 84 | 0.09 | 2.1e-06 | 4.4 | 5.1 | 2.8e-07 | 0.15 | 0.03 | 0.95 | FALSE |