Best TWAS P=3.54e-09 · Best GWAS P=1.36e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | ZNF605 | 0.23 | 0.07 | lasso | 9 | 0.06 | 4.5e-03 | 6.4 | 5.9 | 3.5e-09 | 0.96 | 0.01 | 0.96 | TRUE |
| 2 | GTEx | Muscle Skeletal | ANKLE2 | 0.06 | 0.01 | enet | 17 | 0.03 | 8.8e-04 | 6.4 | 5.9 | 4.8e-09 | 0.74 | 0.00 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ANKLE2 | 0.04 | 0.02 | lasso | 2 | 0.02 | 5.8e-06 | 6.3 | 5.8 | 7.4e-09 | 0.96 | 0.00 | 1.00 | FALSE |