[Hub]/) : Traits : Waist circumference : ← →

chr12:121,194,565-124,162,750

Best TWAS P=3.39e-10 · Best GWAS P=5.07e-11 conditioned to 0.00548

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	TMEM120B	0.11	0.04	lasso	3	0.08	1.9e-09	4.7	6.2	6.4e-10	0.72	0.06	0.94	TRUE
2	GTEx	Brain Cerebellum	TMEM120B	0.28	0.06	enet	18	0.04	2.6e-02	6.6	-5.2	2.4e-07	-0.63	0.00	0.93	FALSE
3	GTEx	Cells Transformed fibroblasts	BCL7A	0.06	0.01	lasso	4	0.01	3.1e-02	4.1	-5.8	8.4e-09	-0.23	0.09	0.07	FALSE
4	GTEx	Colon Transverse	MLXIP	0.20	0.18	enet	23	0.14	5.8e-07	5.6	5.6	2.6e-08	0.11	0.47	0.53	FALSE
5	GTEx	Esophagus Mucosa	KDM2B	0.11	0.04	enet	22	0.10	4.1e-07	2.2	6.3	3.4e-10	0.03	0.91	0.02	TRUE
6	GTEx	Esophagus Mucosa	HIP1R	0.21	0.05	lasso	5	0.07	1.5e-05	3.2	5.1	2.9e-07	0.02	0.57	0.10	FALSE
7	GTEx	Nerve Tibial	AC084018.1	0.18	0.09	lasso	3	0.11	4.8e-08	4.0	-5.2	2.2e-07	-0.62	0.96	0.03	FALSE
8	GTEx	Skin Sun Exposed Lower leg	WDR66	0.19	0.10	lasso	5	0.08	5.5e-07	4.1	5.3	1.1e-07	0.35	0.85	0.14	TRUE
9	GTEx	Stomach	RP11-347I19.8	0.22	0.09	lasso	7	0.11	4.2e-06	3.9	-5.5	4.1e-08	-0.64	0.29	0.70	FALSE
10	METSIM	Adipose	ABCB9	0.04	0.03	enet	19	0.03	7.7e-05	-3.3	-5.3	1.2e-07	-0.05	0.11	0.53	TRUE
11	YFS	Blood	PSMD9	0.04	0.03	bslmm	324	0.05	8.2e-15	-5.1	5.8	6.7e-09	0.57	0.90	0.10	FALSE
12	The Cancer Genome Atlas	Colon Adenocarcinoma	LOC338799	0.06	0.03	blup	31	0.05	5.2e-04	4.7	-5.8	5.3e-09	-0.71	0.04	0.48	FALSE
13	The Cancer Genome Atlas	Colon Adenocarcinoma	MLXIP	0.06	0.04	lasso	7	0.02	2.7e-02	5.4	5.2	2.1e-07	0.05	0.02	0.93	FALSE
14	The Cancer Genome Atlas	Esophageal Carcinoma	LOC338799	0.10	0.02	blup	30	0.06	6.9e-03	6.3	-6.1	1.1e-09	-0.78	0.00	0.77	TRUE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LOC338799	0.06	0.09	lasso	6	0.10	2.1e-11	3.9	-5.7	1.5e-08	-0.74	0.24	0.76	FALSE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	LOC338799	0.04	0.02	blup	29	0.04	3.5e-05	3.9	-5.6	1.8e-08	-0.66	0.14	0.59	FALSE
17	The Cancer Genome Atlas	Stomach Adenocarcinoma	MLXIP	0.06	0.02	blup	68	0.04	1.2e-03	5.5	5.9	2.8e-09	0.05	0.02	0.87	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	VPS33A	0.06	0.00	enet	8	0.03	9.6e-04	4.3	-5.3	1.4e-07	-0.08	0.05	0.92	TRUE