Best TWAS P=2.54e-10 · Best GWAS P=2.75e-13 conditioned to 6.12e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | KLC1 | 0.15 | 0.03 | lasso | 3 | 0.06 | 4.6e-03 | 4.7 | 5.3 | 1.2e-07 | -0.03 | 0.03 | 0.62 | TRUE |
| 2 | GTEx | Esophagus Muscularis | KLC1 | 0.07 | 0.01 | enet | 10 | 0.02 | 2.6e-02 | -4.4 | 5.2 | 1.9e-07 | -0.04 | 0.03 | 0.68 | FALSE |
| 3 | METSIM | Adipose | TRAF3 | 0.04 | 0.02 | enet | 7 | 0.04 | 4.5e-06 | 6.3 | 6.3 | 2.5e-10 | 0.79 | 0.04 | 0.96 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C14orf153 | 0.09 | 0.08 | blup | 38 | 0.09 | 6.2e-10 | -4.7 | -5.1 | 3.1e-07 | 0.04 | 0.00 | 0.98 | FALSE |