Best TWAS P=6.7e-08 · Best GWAS P=3.13e-08 conditioned to 1.3e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | DMXL2 | 0.17 | 0.13 | lasso | 3 | 0.06 | 4.2e-03 | 5.5 | 5.3 | 1.3e-07 | 0.47 | 0.05 | 0.90 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | TMOD2 | 0.09 | 0.10 | enet | 8 | 0.10 | 3.0e-08 | -5.2 | -5.1 | 3.0e-07 | -0.20 | 0.08 | 0.92 | FALSE |
| 3 | GTEx | Muscle Skeletal | LYSMD2 | 0.23 | 0.23 | lasso | 4 | 0.21 | 1.6e-20 | -5.3 | 5.4 | 6.7e-08 | 0.24 | 0.06 | 0.94 | TRUE |
| 4 | GTEx | Skin Sun Exposed Lower leg | TMOD3 | 0.07 | 0.07 | enet | 22 | 0.06 | 6.0e-06 | -5.2 | 5.3 | 9.8e-08 | 0.20 | 0.06 | 0.94 | FALSE |