[Hub]/) : Traits : Waist circumference :

chr19:1,127,720-2,732,986

Best TWAS P=1.74e-11 · Best GWAS P=1.57e-12 conditioned to 0.0597

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex REXO1 0.07 0.01 bslmm 391 0.01 1.7e-02 -3.3 6.7 2.8e-11 -0.51 0.13 0.54 TRUE
2 GTEx Esophagus Muscularis KLF16 0.17 0.07 enet 9 0.09 3.7e-06 -5.5 -5.2 1.7e-07 0.50 0.60 0.20 FALSE
3 GTEx Esophagus Muscularis CTB-31O20.6 0.16 0.07 lasso 5 0.05 7.8e-04 -5.5 -5.5 5.1e-08 0.50 0.59 0.05 FALSE
4 GTEx Thyroid BTBD2 0.18 0.01 lasso 4 0.06 2.4e-05 -5.4 -5.5 4.1e-08 0.18 0.64 0.03 TRUE
5 ROSMAP Brain Pre-frontal Cortex KLF16 0.12 0.08 bslmm 372 0.08 1.0e-10 -7.1 -6.1 1.0e-09 0.85 0.00 1.00 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ATP8B3 0.06 0.00 blup 49 0.03 2.7e-04 -2.2 -5.9 3.8e-09 0.54 0.06 0.18 FALSE
7 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ATP8B3 0.04 0.01 blup 49 0.02 2.2e-03 -7.1 -6.7 1.7e-11 0.84 0.00 0.76 TRUE