TWAS hub - BTBD2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1500	0.0310	3.8e-09	0.117	0.064	0.094	0.095	0.111	4.7e-14	2.7e-08	1.7e-11	1.4e-11	2.0e-13
2	GTEx	Adipose Subcutaneous	0.1240	0.0400	2.0e-03	0.088	NA	0.078	NA	0.074	1.2e-07	NA	6.5e-07	NA	1.3e-06
3	GTEx	Artery Tibial	0.1410	0.0444	1.0e-03	0.106	NA	0.059	NA	0.102	1.2e-08	NA	2.0e-05	NA	2.2e-08
4	GTEx	Cells Transformed fibroblasts	0.2420	0.0550	1.1e-05	0.011	NA	0.048	NA	0.037	4.3e-02	NA	1.6e-04	NA	9.0e-04
5	GTEx	Esophagus Muscularis	0.1710	0.0510	2.1e-04	0.071	NA	0.062	NA	0.089	3.9e-05	NA	1.2e-04	NA	4.5e-06
6	GTEx	Nerve Tibial	0.2590	0.0617	1.2e-05	0.234	NA	0.255	NA	0.277	1.4e-16	NA	4.3e-18	NA	8.1e-20
7	GTEx	Thyroid	0.1790	0.0520	1.3e-04	0.011	NA	0.045	NA	0.060	4.5e-02	NA	2.4e-04	NA	2.4e-05
8	YFS	Blood	0.0897	0.0227	2.7e-07	0.017	0.029	0.033	0.033	0.013	1.6e-06	5.5e-10	4.5e-11	5.0e-11	3.3e-05
9	TCGA	Lung Adenocarcinoma	0.0625	0.0321	7.6e-04	0.022	0.020	0.012	NA	0.019	1.3e-03	1.8e-03	1.4e-02	NA	2.4e-03
10	TCGA	Prostate Adenocarcinoma	0.0380	0.0188	1.3e-03	0.023	0.028	0.005	NA	0.018	1.8e-03	5.5e-04	8.8e-02	NA	5.2e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Overall health rating	5.7	12.3	31.5	3.5	-3.1	-3.2	-3.8	-3.8	-1.2	-5.6	-0.0	-2.5	-4.8
Reason for reducing amount of alcohol drunk: Health precaution	4.6	5.4	11.6	-2.7	1.8	2.4	-0.5	2.5	-1.6	3.4	-1.6	2.1	3.2
Heart attack	4.2	5.4	10.5	2.3	-2.1	-2.4	-2.0	-2.7	-2.3	-2.3	0.5	-2.3	-3.2
Glaucoma (self-reported)	4.1	4.8	12.5	-2.1	2.3	2.0	2.8	2.3	1.2	1.2	1.6	3.5	2.0
Waist circumference	3.7	13.5	30.1	4.0	-4.1	-4.0	-2.5	-4.6	-0.6	-5.5	-0.1	-3.1	-4.3
Angina (self-reported)	3.7	4.8	10.1	2.3	-2.0	-2.2	-1.8	-2.6	-1.5	-2.7	0.5	-2.1	-3.2
Angina	3.6	4.7	10.1	2.2	-2.1	-2.2	-1.5	-2.5	-1.4	-2.9	0.6	-2.0	-3.2
Prostate Cancer	3.5	4.9	8.6	-2.7	1.9	2.6	0.7	2.5	1.7	2.9	-1.4	1.9	2.7
Commuting to job workplace: Walk	3.5	3.8	7.2	-2.3	2.3	2.7	-0.3	2.0	0.2	1.2	-2.1	2.5	2.0
Unable to work because of sickness or disability	3.4	4.4	8.5	2.6	-0.9	-2.1	-1.5	-2.6	0.0	-2.8	1.8	-1.6	-2.9
Heart attack/myocardial infarction (self-reported)	3.4	4.4	8.9	2.0	-1.9	-2.1	-1.9	-2.5	-2.1	-2.1	0.1	-2.1	-3.0
Body mass index (BMI)	3.1	13.4	28.0	3.9	-4.2	-4.0	-1.7	-4.5	-0.4	-5.3	0.2	-3.4	-4.7
Alcohol usually taken with meals	3.1	5.1	9.2	-2.6	2.7	2.6	0.6	3.0	0.2	2.6	-0.9	2.7	2.3
BMI	3.0	17.1	30.8	4.6	-4.7	-4.7	-2.5	-5.5	-1.2	-5.1	0.5	-3.9	-5.1
Arm fat mass (right)	2.9	12.1	23.6	3.9	-4.0	-3.9	-2.3	-4.2	-0.4	-4.9	0.1	-3.2	-4.2
Arm fat mass (left)	2.9	12.1	23.4	3.9	-4.1	-3.9	-2.2	-4.2	-0.2	-4.8	0.0	-3.2	-4.1
Ever depressed for a whole week	2.9	3.6	6.4	-2.2	1.3	2.3	-0.3	2.5	0.6	2.0	-1.3	2.4	2.4
Cholesterol lowering medication	2.9	4.3	8.5	2.4	-2.2	-2.2	0.1	-2.9	0.2	-2.0	-1.8	-2.8	-2.0
Wheeze or whistling in the chest in last year	2.8	4.9	12.6	2.2	-1.5	-2.0	-1.8	-3.5	0.6	-3.4	-0.6	-1.7	-2.6
Medication: Gliclazide	2.8	3.2	8.6	1.4	-1.7	-1.6	-1.4	-1.2	-2.1	-1.8	-2.9	-1.1	-2.0
Health satisfaction	2.7	3.5	6.6	2.6	-2.4	-2.3	-1.5	-1.8	-0.3	-2.4	1.0	-0.6	-2.1
Maternal smoking around birth	2.6	3.8	13.2	1.7	-2.0	-1.6	-2.0	-2.1	-0.7	-3.6	-0.1	-1.4	-2.1
Hip circumference	2.6	11.3	23.2	4.0	-3.8	-3.7	-2.9	-3.6	-0.0	-4.8	0.3	-2.9	-3.9
Arm fat percentage (left)	2.6	10.3	19.8	3.3	-3.7	-3.4	-1.9	-4.3	-1.1	-4.5	-0.2	-3.0	-3.9
Medication for cholesterol	2.6	3.9	6.7	-2.5	1.9	2.4	0.9	2.6	0.4	2.3	0.9	1.9	2.4
Pack years of smoking	2.6	3.7	6.2	2.2	-2.3	-2.2	-1.6	-2.5	-0.7	-1.7	-0.5	-2.5	-1.9
Rheumatoid Arthritis	2.5	3.4	7.3	2.4	-2.6	-2.7	0.0	-2.5	-1.0	-2.6	0.0	0.0	0.0
Arm fat percentage (right)	2.5	10.0	20.5	3.3	-3.6	-3.4	-1.8	-4.1	-1.2	-4.5	0.1	-2.9	-3.8
Leg pain on walking	2.5	3.2	8.7	1.9	-1.8	-1.8	-1.2	-2.5	-0.2	-3.0	-0.4	-1.2	-2.0
Townsend deprivation index at recruitment	2.4	3.4	11.8	1.5	-1.8	-1.3	-2.2	-2.0	-0.9	-3.4	1.1	0.1	-1.9
Financial difficulties in last 2 years	2.4	3.2	9.0	1.7	-1.4	-1.7	-1.9	-2.0	-0.7	-3.0	1.9	0.5	-1.9
Medication: Metformin	2.3	3.2	5.5	1.4	-1.8	-1.5	-1.7	-1.5	-2.2	-2.2	-1.8	-1.1	-2.4
Impedance of leg (right)	2.3	11.2	20.6	-3.7	3.9	4.0	1.5	4.2	-0.3	3.8	-0.4	3.4	4.5
Impedance of leg (left)	2.3	11.0	20.2	-3.7	3.8	4.0	1.5	4.3	0.1	3.8	-0.3	3.2	4.5
Diabetes (self-reported)	2.3	3.6	5.8	1.9	-1.8	-2.0	-2.2	-1.9	-1.4	-2.4	-0.2	-1.9	-2.2
Weight	2.3	11.5	22.8	4.0	-3.8	-3.9	-2.5	-3.8	0.7	-4.8	-0.1	-3.0	-4.0
Worry too long after embarrassment	2.3	3.8	9.7	-2.3	1.4	2.0	1.5	3.1	2.0	1.4	0.7	1.0	2.8
Qualifications: NVQ or HND or HNC or equivalent	2.3	2.8	7.2	1.3	-1.8	-1.3	-1.1	-1.3	-2.1	-2.7	0.4	-1.3	-2.2
Diabetes diagnosed by doctor	2.3	3.8	8.0	2.0	-1.5	-2.1	-2.1	-2.0	-1.9	-2.3	-0.5	-1.5	-2.8
Medication: Levothyroxine sodium	2.2	3.8	7.2	2.5	-2.3	-2.5	-1.1	-2.1	0.1	-1.6	1.0	-2.7	-2.1
Qualifications: None of the above	2.2	4.7	8.5	2.6	-2.5	-2.5	-1.3	-2.5	-1.3	-2.4	-1.0	-1.7	-2.9
Whole body fat mass	2.2	9.1	19.8	3.4	-3.5	-3.3	-1.8	-3.5	-0.4	-4.5	-0.1	-2.9	-3.6
Age at last live birth	2.2	3.1	6.6	-1.5	2.4	1.3	2.6	1.7	0.7	1.6	1.7	2.0	1.4
Average weekly beer plus cider intake	2.2	3.2	6.4	2.1	-1.9	-1.9	-1.1	-1.6	-1.1	-2.4	-0.8	-1.5	-2.5
Trunk fat mass	2.1	9.1	17.8	3.3	-3.4	-3.3	-2.2	-3.6	-0.5	-4.2	-0.3	-3.0	-3.6
Qualifications: A levels/AS levels or equivalent	2.1	4.6	8.9	-2.4	2.3	2.5	0.6	3.0	-0.5	2.7	1.1	1.9	2.8
Birth weight of first child	2.1	3.8	8.2	1.8	-2.1	-2.1	-0.2	-2.9	-1.1	-2.4	0.6	-2.3	-2.2
Long-standing illness, disability or infirmity	2.1	3.2	8.5	2.2	-2.1	-2.0	-1.0	-1.3	-1.4	-2.1	-0.6	-0.9	-2.9
Pain type(s) experienced in last month: Hip pain	2.1	2.6	8.5	1.2	-0.6	-1.0	-2.1	-1.9	1.0	-2.9	0.7	-0.6	-2.3
Ovarian Cancer	2.0	2.6	6.5	2.6	-1.4	-2.5	-0.3	-1.8	1.0	-0.7	-0.0	-0.0	-2.5
Type 2 Diabetes (T2D) (2018)	2.0	3.7	7.2	2.0	-1.7	-2.3	-1.6	-2.2	-1.7	-2.7	-0.2	-1.3	-2.3
Pack years adult smoking proportion	2.0	3.0	5.1	2.1	-2.0	-2.0	-1.7	-2.2	-0.6	-1.5	-0.5	-2.0	-1.8
Frequency of tiredness / lethargy in last 2 weeks	2.0	3.3	12.0	1.4	-1.8	-1.2	-1.7	-1.8	-0.7	-3.5	1.1	-1.2	-2.1
Qualifications: College or University degree	2.0	6.3	12.7	-2.2	2.5	1.9	2.0	3.0	0.4	3.6	0.9	3.2	3.3
Leg fat-free mass (left)	1.9	10.2	16.9	3.9	-3.5	-3.8	-2.3	-3.5	1.3	-4.1	0.0	-3.0	-3.8
Leg predicted mass (left)	1.9	10.1	16.2	3.9	-3.5	-3.8	-2.3	-3.5	1.2	-4.0	0.1	-3.1	-3.8
Length of working week for main job	1.9	2.1	9.1	-1.1	1.7	1.4	0.9	1.2	1.1	-0.1	3.0	1.1	1.0
Exposure to tobacco smoke outside home	1.9	2.5	5.6	1.2	-1.4	-0.9	-2.4	-1.4	-1.5	-2.0	-0.3	-1.5	-2.2
Age at first live birth	1.9	3.4	8.7	-1.6	2.3	1.2	2.9	1.6	1.1	2.5	1.1	1.3	1.7
Leg fat mass (right)	1.9	7.4	19.5	2.9	-3.0	-2.8	-1.6	-3.0	-0.6	-4.4	-0.0	-2.5	-3.3
Had major operations	1.9	2.3	3.9	-1.6	1.8	1.7	1.3	1.4	-0.9	1.2	-1.6	2.0	1.3
Leg fat-free mass (right)	1.9	10.1	15.5	3.9	-3.5	-3.8	-2.4	-3.4	1.4	-3.9	0.1	-3.1	-3.8
Leg predicted mass (right)	1.9	10.1	15.2	3.9	-3.5	-3.8	-2.3	-3.4	1.5	-3.9	0.1	-3.2	-3.8
Leg fat mass (left)	1.9	7.6	18.7	3.0	-3.1	-2.9	-1.7	-3.0	-0.3	-4.3	0.0	-2.6	-3.4
Impedance of whole body	1.8	9.0	17.5	-3.5	3.5	3.8	1.0	3.2	-0.7	3.8	-0.2	2.6	4.2
Medication: Simvastatin	1.7	2.4	3.5	1.7	-1.7	-1.5	-1.4	-1.6	-1.7	-0.8	-1.4	-1.9	-1.6
Hearing aid user	1.7	2.0	3.5	1.5	-1.5	-1.6	-1.9	-1.1	-1.7	-1.1	-0.2	-1.3	-1.5
Trunk fat percentage	1.6	6.4	13.5	2.6	-2.8	-2.6	-1.6	-3.3	-0.8	-3.7	0.0	-2.6	-3.0
Body fat percentage	1.6	6.4	15.4	2.5	-2.8	-2.5	-1.5	-3.2	-0.9	-3.9	0.1	-2.4	-3.0
Wears glasses or contact lenses	1.6	1.8	4.3	-1.7	0.8	1.6	-0.6	1.7	-2.1	1.2	-1.1	1.0	1.1
Illnesses of father: High blood pressure	1.6	2.0	6.6	-1.3	1.1	1.4	2.6	2.1	1.6	-0.3	0.1	1.0	0.7
Basal metabolic rate	1.6	8.7	15.3	3.8	-3.2	-3.6	-2.3	-3.0	1.6	-3.9	-0.1	-2.5	-3.4
Diabetes (mother)	1.5	2.0	4.0	1.9	-1.5	-2.0	-0.8	-1.8	-0.9	-0.9	-0.8	-0.8	-1.6
Pulse wave reflection index	1.5	1.9	6.1	-1.1	1.9	1.2	0.3	0.9	1.3	-0.4	2.5	2.0	0.0
Emphysema/chronic bronchitis	1.5	1.6	2.7	1.6	-1.0	-1.7	-1.3	-1.3	0.7	-1.5	-0.4	-1.5	-1.3
Ever taken oral contraceptive pill	1.5	1.6	3.9	-1.0	0.5	1.0	0.6	1.3	1.6	2.0	0.4	1.3	1.9
Age at First Birth	1.4	2.1	4.2	-1.5	1.5	1.4	1.3	1.9	0.9	1.6	-0.1	2.1	1.2
Diverticular disease/diverticulitis (self-reported)	1.4	1.7	3.6	1.0	-1.1	-1.0	-1.1	-1.9	-1.3	-1.9	-1.2	-0.5	-1.4
Pain all over the body in last month	1.4	1.5	4.1	1.1	-1.0	-1.0	-0.5	-1.8	-0.4	-2.0	-0.2	-1.5	-1.3
Breastfed as a baby	1.4	1.7	8.4	0.3	-0.6	-0.3	-2.9	-0.2	-1.7	0.8	-1.9	0.5	-0.9
Qualifications: O levels/GCSEs or equivalent	1.4	2.3	4.4	-2.1	1.9	2.0	0.1	1.7	-0.5	1.1	1.2	0.6	2.0
Commuting to job workplace: Car/motor vehicle	1.4	1.6	3.8	1.6	-1.1	-1.5	0.0	-1.5	-1.1	-0.7	0.6	-1.1	-2.0
Whole body water mass	1.4	7.9	13.3	3.6	-3.0	-3.5	-2.2	-2.7	1.8	-3.6	-0.3	-2.5	-3.2
Arm fat-free mass (left)	1.4	6.9	13.6	3.4	-2.8	-3.2	-1.9	-2.3	1.8	-3.7	0.2	-2.2	-3.0
Hearing difficulty/problems: Yes	1.3	2.0	3.5	1.9	-1.7	-1.7	-1.6	-1.7	0.3	-1.1	0.7	-0.4	-1.9
Had menopause	1.3	1.7	11.7	-1.1	0.4	1.2	-0.2	0.2	-1.3	0.5	-3.4	-0.3	0.5
Arm predicted mass (right)	1.3	6.8	11.8	3.3	-2.9	-3.1	-1.9	-2.4	1.9	-3.4	-0.1	-2.3	-3.0
Whole body fat-free mass	1.3	7.4	12.5	3.5	-2.8	-3.3	-2.1	-2.6	1.8	-3.5	-0.2	-2.3	-3.1
Loneliness, isolation	1.3	1.7	4.0	1.4	-1.2	-1.4	-1.4	-1.3	0.8	-2.0	1.2	-0.5	-1.5
Friendships satisfaction	1.3	1.6	3.7	-1.3	0.2	1.4	-1.9	1.6	-0.2	0.4	-0.8	1.9	1.5
Back pain experienced in last month	1.3	1.9	4.3	1.4	-0.7	-1.2	-1.9	-1.6	0.3	-2.1	-0.3	-0.8	-2.0
Eye problems/disorders: Glaucoma	1.3	1.6	4.0	-1.5	1.5	1.3	1.3	1.6	0.3	-0.2	0.8	2.0	0.5
Medication: Paracetamol	1.3	2.0	10.0	1.1	-0.6	-1.5	0.1	-1.1	0.2	-1.2	3.2	-0.0	-1.7
Leg fat percentage (left)	1.3	4.6	13.0	2.0	-2.4	-1.9	-1.3	-2.3	-0.8	-3.6	-0.1	-2.0	-2.9
Blood Platelet Count	1.2	13.6	47.1	2.6	-3.3	-3.0	-3.6	-3.7	-6.9	-1.9	-1.4	-1.7	-5.2
Lung FVC	1.2	5.9	11.8	-3.4	2.1	2.7	3.1	2.4	-0.9	1.7	-0.4	3.4	2.1
Ever used hormone-replacement therapy (HRT)	1.2	1.5	10.7	-0.2	-0.7	0.2	-1.4	-0.5	-1.1	0.1	-3.3	-0.8	-0.1
Supplements: Glucosamine	1.2	1.6	2.8	-1.6	1.2	1.6	1.2	1.7	-0.8	0.3	0.8	1.2	1.4
Medication: Paracetamol	1.2	2.1	8.1	1.6	-1.0	-1.8	-0.2	-1.3	0.4	-0.9	2.8	-0.5	-1.6
Leg fat percentage (right)	1.2	4.2	13.2	1.8	-2.2	-1.7	-1.2	-2.2	-1.1	-3.6	-0.1	-1.8	-2.6
Shortness of breath walking on level ground	1.2	1.4	3.8	1.3	-1.3	-1.2	-1.2	-1.1	1.9	-1.3	0.0	0.1	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	3.5	1.2	-0.8	-1.3	0.1	-1.9	-0.6	-1.2	0.5	-1.1	-1.8
High cholesterol (Self-reported)	1.2	2.2	4.0	1.5	-1.5	-1.4	-0.7	-1.9	-0.5	-1.1	-1.7	-2.0	-1.8
Arm predicted mass (left)	1.2	6.3	12.7	3.3	-2.5	-3.1	-1.7	-2.1	2.0	-3.6	0.4	-2.1	-2.8
HbA1C	1.1	1.2	4.1	1.2	-1.2	-1.4	-1.2	-0.0	-0.3	-0.1	2.0	-1.1	-0.7
Neuroticism (2016)	1.1	1.6	2.6	1.2	-1.6	-0.9	-1.3	-1.2	0.2	-1.4	-1.6	-1.2	-1.3
Hand grip strength (left)	1.1	2.8	8.8	2.2	-1.5	-2.0	0.4	-1.5	3.0	-1.3	1.7	-0.7	-0.8
Ever had hysterectomy (womb removed)	1.1	1.2	2.9	0.8	-1.0	-0.8	-1.4	-1.1	-1.7	-1.5	0.8	-0.7	-0.9
Relative age voice broke	1.1	1.8	4.8	-1.0	0.8	0.7	0.8	1.4	2.2	0.9	1.1	2.0	1.3
Chronic bronchitis/emphysema (father)	1.1	1.3	7.0	-0.9	1.3	0.9	0.3	0.4	1.0	2.6	0.1	-0.2	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.5	7.6	-2.3	1.8	1.9	-0.3	2.2	-0.1	2.3	0.6	2.8	2.1
Birth weight	1.1	2.5	5.8	1.4	-1.2	-1.8	1.1	-2.2	-0.7	-1.5	0.4	-2.4	-1.8
Arm fat-free mass (right)	1.1	5.4	10.3	3.0	-2.4	-2.7	-1.6	-2.0	2.0	-3.2	-0.3	-2.1	-2.6
Ever had bowel cancer screening	1.1	1.3	2.5	-1.2	1.0	1.4	-0.0	0.6	-1.1	0.5	-1.5	1.6	1.4
Osteoarthritis (self-reported)	1.1	1.4	2.6	1.6	-1.2	-1.4	-0.7	-1.3	-0.0	-1.0	-0.3	-1.6	-1.4
Financial situation satisfaction	1.1	1.3	3.8	1.1	-1.3	-1.2	-1.9	-0.1	-2.0	0.2	1.1	0.3	-0.5
Risk taking	1.1	1.6	6.9	0.8	-0.4	-0.7	0.6	-1.7	-0.2	-2.6	1.5	-0.9	-1.3
Mean Putamen Volume	1.0	1.1	2.4	-1.5	0.7	1.5	0.5	0.9	0.5	0.9	0.3	1.5	1.3
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	2.6	1.6	-1.5	-1.5	-0.8	-1.1	-0.6	-0.3	-0.1	-1.6	-0.7
Hayfever, allergic rhinitis or eczema	1.0	2.1	4.3	-1.4	1.4	1.4	0.6	1.2	1.7	1.3	1.6	1.4	2.1
Impedance of arm (right)	1.0	4.5	9.6	-2.4	2.5	2.5	0.4	1.8	-1.5	2.8	-0.4	1.8	3.1
Father’s age at death	1.0	1.3	2.4	-0.7	1.0	0.8	1.0	1.5	1.1	1.5	-1.6	0.7	1.4
Impedance of arm (left)	1.0	4.7	10.9	-2.5	2.4	2.6	0.1	1.7	-1.3	3.3	-0.6	1.7	3.0
Ever highly irritable/argumentative for 2 days	1.0	1.2	3.2	1.1	-1.0	-1.0	-1.0	-1.2	-1.1	-1.5	1.8	-0.1	-0.3
Medication: Blood pressure	1.0	1.7	6.5	-0.3	0.2	0.4	-0.8	-0.6	-2.4	-2.5	-1.6	0.2	-1.3
Qualifications: nursing, teaching	1.0	1.6	5.7	-0.6	0.4	0.6	2.4	0.8	0.3	2.0	-1.7	0.1	1.4
Alcohol drinker status: Never	1.0	1.2	4.1	0.7	-0.3	-0.4	-1.9	-0.7	-2.0	-0.9	0.5	-0.4	-1.3
Ever had prostate specific antigen (PSA) test	1.0	1.1	2.9	-0.9	0.1	0.8	-1.1	1.2	-1.7	1.3	-1.2	0.7	0.9
Intelligence (Savage-Jansen 2018)	0.9	2.7	10.7	-1.3	0.8	1.1	-0.6	2.0	-0.3	3.3	-1.2	-0.5	2.5
Blood Eosinophil Count	0.9	6.9	14.4	3.6	-3.2	-3.8	-2.3	-2.0	-0.9	-1.7	0.0	-2.1	-3.7
Medication: Atenolol	0.9	1.2	4.2	-1.5	2.0	1.5	0.2	0.5	0.2	-0.9	-0.6	1.0	0.6
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	4.5	-0.7	-0.2	0.7	-1.7	1.1	-0.8	0.2	-0.7	2.1	0.7
Trunk fat-free mass	0.9	5.2	9.4	3.1	-2.3	-2.8	-2.1	-1.9	1.7	-2.9	-0.7	-1.6	-2.5
Noisy workplace	0.9	1.1	3.1	1.6	-1.2	-1.8	-0.0	-1.4	0.2	-0.1	0.7	-0.4	-0.9
Mouth/teeth dental problems: Dentures	0.9	1.6	8.4	0.7	-1.1	-0.7	0.5	-0.7	-0.9	-2.9	-0.5	-1.3	-1.3
Trunk predicted mass	0.9	5.3	9.7	3.1	-2.3	-2.9	-2.1	-1.9	1.7	-3.0	-0.6	-1.7	-2.5
Forced vital capacity (FVC), Best measure	0.9	3.3	7.4	-2.0	1.7	1.9	0.6	2.3	0.9	2.0	0.3	2.7	2.1
Number of full brothers	0.9	1.2	3.6	1.3	-1.9	-1.1	-0.9	-0.3	-1.4	-0.5	0.6	-0.6	-1.0
Alcohol intake frequency.	0.9	2.0	5.0	1.5	-0.5	-1.1	-0.9	-1.4	0.3	-2.2	1.8	-0.8	-2.2
Mineral and other dietary supplements	0.9	1.2	2.1	1.2	-0.8	-1.2	-0.1	-1.4	1.2	-1.3	0.4	-1.3	-1.2
Osteoporosis (self-reported)	0.9	1.1	3.2	-0.9	1.2	1.0	1.2	1.1	-0.1	0.6	1.8	0.3	1.3
Average weekly champagne plus white wine intake	0.9	1.2	2.9	-1.4	0.9	1.4	0.9	0.8	-1.0	0.5	-1.7	1.2	0.1
Systolic Blood Pressure	0.8	3.8	13.6	-1.9	3.7	2.2	2.1	1.6	0.5	0.2	1.6	1.9	1.4
Average weekly spirits intake	0.8	1.0	2.6	1.1	-0.6	-1.2	0.6	-1.6	-0.8	-0.5	0.2	-1.5	-1.1
Fed-up feelings	0.8	1.4	3.2	1.5	-1.8	-1.5	-0.0	-0.7	0.8	-1.7	-0.3	-0.9	-1.1
Qualifications: CSEs or equivalent	0.8	1.0	2.5	1.3	-1.6	-1.3	0.0	-0.9	1.4	-1.0	-0.6	-0.1	-0.8
Forced vital capacity (FVC)	0.8	3.2	6.4	-2.1	1.6	1.9	0.6	2.2	0.6	1.9	0.3	2.5	2.3
Alcohol intake versus 10 years previously	0.8	1.1	2.9	1.0	-0.6	-0.9	-1.7	-1.5	-0.9	-0.8	1.4	-0.3	-0.8
Asthma	0.8	1.6	7.5	1.5	-0.2	-1.3	-0.1	-1.5	1.3	0.2	2.7	-0.2	-0.3
Lung cancer (father)	0.8	0.9	3.4	-0.7	0.5	0.9	-1.8	-0.3	-1.3	-0.6	-1.4	0.2	-0.7
Pulse wave Arterial Stiffness index	0.8	0.9	2.4	1.5	-0.4	-1.2	0.5	-0.4	1.1	0.1	0.8	-1.1	-1.3
Headache pain in last month	0.8	1.4	6.1	-0.7	1.3	0.6	1.2	0.0	2.0	0.2	2.5	0.0	0.5
Medication: Amlodipine	0.8	1.2	3.3	1.4	-0.5	-1.3	0.5	-1.2	-0.2	-0.8	0.8	-1.3	-1.8
Pulse wave peak to peak time	0.8	0.9	2.2	-1.5	0.5	1.2	-0.7	0.3	-1.1	-0.1	-0.8	0.9	1.4
Eye problems/disorders: None of the above	0.8	1.0	3.8	0.9	-1.3	-0.6	-1.2	-0.1	-0.4	0.3	-2.0	-1.0	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.8	5.5	-0.8	1.0	1.1	-0.5	1.5	1.2	1.9	0.3	1.2	2.3
Fasting Glucose	0.7	0.8	4.3	-0.2	0.9	0.2	1.4	-0.0	0.3	0.7	2.1	0.1	0.7
Allergy or Eczema	0.7	1.7	4.0	-1.3	1.3	1.2	0.4	1.2	1.4	2.0	-0.1	1.7	1.5
Hypothyroidism (self reported)	0.7	1.6	4.3	1.3	-1.5	-1.3	-1.3	-1.4	1.1	-0.8	0.7	-2.1	-0.7
Medication for hormone replacement therapy	0.7	0.8	3.7	0.3	-1.0	-0.4	-0.4	-0.6	-0.1	-1.9	-1.4	-0.3	-0.5
Age when periods started (menarche)	0.7	1.8	5.8	-1.6	0.5	1.6	-0.4	0.8	-0.2	-1.6	1.6	2.4	0.6
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	4.2	-0.5	0.3	0.5	0.6	1.0	-0.1	-2.0	0.9	0.7	0.1
Stomach or abdominal pain in last month	0.7	0.8	3.0	0.6	-0.3	-0.7	-0.5	-1.0	-0.5	-1.7	1.5	0.2	-0.6
Had other major operations	0.7	0.9	1.9	1.0	-0.9	-1.0	0.2	-0.9	-0.5	-0.8	1.4	-0.5	-1.3
Allergy	0.7	1.7	4.5	0.7	-1.1	-0.8	-0.7	-0.7	-1.9	-1.5	-1.4	-0.9	-2.1
Time employed in main current job	0.7	0.8	2.0	1.0	-1.2	-1.0	-1.4	-0.1	-0.6	1.2	-0.5	-0.6	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	3.6	0.2	-0.2	-0.4	1.9	0.6	1.4	-0.1	0.0	1.5	0.3
Depression (self-reported)	0.7	0.8	3.3	-0.1	0.4	0.1	-0.6	0.7	-0.5	1.8	0.8	1.2	1.2
Loud music exposure frequency	0.7	0.8	2.0	-0.8	-0.1	0.7	-0.2	0.8	0.9	-0.7	1.3	1.4	0.9
Comparative body size at age 10	0.7	2.1	4.3	0.6	-1.8	-1.0	0.5	-2.1	-1.0	-1.4	-1.7	-1.9	-1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	2.9	-0.7	1.5	0.6	1.2	-0.0	1.7	0.1	0.8	0.7	0.5
Supplements: Vitamin C	0.7	0.8	2.4	0.2	-0.1	-0.4	-1.6	-1.2	-0.1	-1.3	-1.0	-0.8	-0.8
Asthma (self-reported)	0.7	1.4	6.3	1.4	-0.2	-1.2	0.0	-1.5	1.3	0.0	2.5	-0.2	-0.2
Mother’s age at death	0.7	0.8	6.5	0.6	-0.1	-0.4	0.6	0.4	-0.3	2.5	-0.7	0.2	0.5
Supplements: Fish oil (including cod liver oil)	0.7	0.8	1.8	-1.0	0.6	1.0	-0.2	0.9	-0.3	1.4	-0.9	1.4	0.8
Medication: Bendroflumethiazide	0.7	1.0	2.8	-0.7	1.7	1.0	-0.3	1.2	0.2	1.2	0.1	1.4	0.8
Age started oral contraceptive pill	0.7	0.9	2.0	-0.7	-0.4	0.7	-0.1	1.4	0.2	1.4	-1.3	0.9	0.9
Supplements: Calcium	0.7	0.8	3.7	1.0	-1.0	-1.0	-0.6	-0.5	-0.2	-0.2	-0.5	-1.9	-0.3
Basal cell carcinoma (self-reported)	0.7	0.8	4.0	-0.3	-0.9	0.2	-1.6	0.4	-2.0	0.1	0.4	0.7	0.3
Reaction Time	0.6	1.2	3.1	-1.4	0.8	1.5	-0.9	0.8	1.3	0.1	1.1	-0.0	1.8
Supplements: Zinc	0.6	0.6	1.5	1.0	-0.8	-1.1	-0.5	-0.8	-0.2	-0.6	-0.7	-0.5	-1.2
Average weekly fortified wine intake	0.6	0.7	3.4	-0.8	-0.0	0.7	0.9	1.0	-0.3	-0.5	-1.9	-0.2	0.7
Taking other prescription medications	0.6	0.9	2.7	-1.0	1.6	1.2	0.6	0.9	-0.1	0.9	-0.1	1.3	0.2
Number of incorrect matches in round	0.6	0.9	2.4	0.7	-0.1	-0.4	1.0	0.4	1.5	1.0	1.4	1.3	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	2.0	-1.3	0.9	1.3	-0.5	1.3	-0.1	0.6	0.8	1.4	0.8
Hearing difficulty/problems with background noise	0.6	1.0	3.0	-0.4	-0.0	0.6	-0.8	1.3	0.9	0.5	1.5	1.7	0.8
Worrier / anxious feelings	0.6	1.2	3.2	-0.9	0.8	1.0	-1.1	1.5	0.5	1.8	-1.2	0.3	0.8
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	3.5	-1.7	1.3	1.4	-0.4	1.7	-0.5	1.7	0.2	1.9	1.7
Exposure to tobacco smoke at home	0.6	0.7	2.4	0.2	-0.4	-0.2	-1.6	-0.6	1.0	-1.0	-0.4	-0.3	-1.4
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	1.8	-0.8	0.6	0.9	-1.3	0.6	-0.5	0.1	1.0	1.4	0.8
Medication for cholesterol, blood pressure or diabetes	0.6	1.1	4.1	0.4	-0.5	-0.6	0.8	0.0	2.0	0.7	1.6	-0.9	1.2
Neck or shoulder pain in last month	0.6	0.9	4.3	0.9	0.2	-0.8	-0.1	-0.3	0.9	-0.5	2.1	-0.7	-1.0
Migraine (self-reported)	0.6	0.7	2.2	-1.1	1.5	0.8	-0.5	0.7	-0.5	1.0	0.6	0.6	0.6
Heart disease (mother)	0.6	0.7	1.3	1.0	-1.0	-0.9	0.1	-0.8	0.9	0.0	1.0	-1.1	-0.6
Number of full sisters	0.6	0.8	2.1	-0.9	1.4	0.9	0.2	0.1	0.7	-0.4	1.2	1.4	-0.2
Chest pain or discomfort	0.6	0.9	1.9	0.8	-0.7	-1.1	0.5	-0.6	0.6	-1.4	1.3	-0.9	-0.9
Illnesses of father: Heart disease	0.6	0.8	1.3	1.2	-0.9	-1.1	-0.7	-0.8	0.7	-1.1	0.5	-1.0	-0.5
Illnesses of siblings: Diabetes	0.6	0.7	2.5	-1.1	0.6	1.2	0.7	0.5	0.9	-0.2	0.0	-0.2	1.6
Smoking status: Current	0.6	0.9	3.4	0.3	-0.4	-0.3	-0.8	-1.2	0.3	-1.6	-1.8	0.5	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	5.2	-0.4	-0.0	-0.1	-0.3	0.7	-2.3	1.7	-0.5	1.8	-0.5
Pain experienced in last month	0.6	0.9	3.2	-0.6	0.0	0.4	1.0	0.8	-1.0	1.8	-1.5	0.3	0.8
Heart disease (siblings)	0.6	0.8	3.0	1.1	-1.7	-1.1	0.4	-0.4	-0.3	-1.1	-0.0	0.3	-0.9
Depressed Affect (Nagel 2018)	0.5	1.0	2.1	1.2	-1.2	-1.0	-1.4	-1.0	-0.4	-0.9	-0.5	-1.1	-0.9
Schizophrenia (2018)	0.5	1.1	6.1	0.0	0.0	1.8	0.0	2.5	0.4	1.1	0.0	0.0	0.0
Primary Biliary Cirrhosis	0.5	0.8	4.2	0.5	-0.5	-0.4	-0.3	-0.3	-1.2	-0.1	-2.0	0.0	-1.1
Chronotype (morning person)	0.5	1.2	6.3	-0.9	0.2	0.9	-1.5	0.9	-2.5	-0.0	-0.4	0.6	0.9
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.6	0.2	0.5	-0.2	0.1	-1.3	-0.4	-1.3	1.2	-0.3	-0.5
Medication: Co-codamol	0.5	0.6	2.3	1.1	-0.2	-1.1	0.4	-0.7	0.2	0.3	0.3	-0.1	-1.5
Severe depression (siblings)	0.5	0.6	1.5	1.2	-1.1	-1.0	-0.9	-0.8	0.3	-0.2	-0.0	-0.4	-0.6
Hand grip strength (right)	0.5	1.5	5.3	1.6	-1.4	-1.3	-1.0	-0.2	2.3	-0.3	1.4	0.2	-0.0
Current tobacco smoking	0.5	0.9	3.5	0.1	-0.3	-0.1	-0.8	-0.9	0.5	-1.7	-1.9	0.6	-0.5
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	2.1	0.1	-0.2	-0.0	-1.4	1.0	-0.9	0.4	-0.1	1.1	0.2
Serious illness, injury or assault to yourself	0.5	0.6	1.2	-0.7	1.1	1.0	-0.4	0.9	-0.8	-0.3	0.5	1.0	0.7
Sitting height	0.5	3.7	7.2	2.7	-1.8	-2.4	-1.8	-1.8	0.5	-2.1	-0.8	-2.4	-1.8
High blood pressure (mother)	0.5	0.6	1.3	1.1	-1.0	-1.1	-0.8	-0.6	0.7	-0.5	-0.2	-0.9	-0.6
Nervous feelings	0.5	0.9	6.1	0.1	0.1	0.1	-0.8	1.0	0.1	2.5	-0.2	-0.2	1.2
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	2.9	-0.9	0.3	0.7	-0.4	0.3	1.1	-0.3	1.0	0.6	1.7
Pulse rate	0.5	0.8	2.4	1.3	-0.9	-1.3	0.1	-1.1	-0.0	-0.2	0.1	-1.6	-0.7
Medication: Lansoprazole	0.5	0.6	3.9	-0.4	0.3	0.4	0.1	-0.9	-0.0	-0.8	-2.0	0.1	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	4.8	-0.4	-0.4	0.8	-2.2	0.0	-0.7	-0.5	-0.6	0.3	0.4
Gout (self-reported)	0.5	0.7	2.9	0.2	-0.2	-0.3	-1.7	-0.5	-1.3	0.7	-0.3	-0.5	0.9
Family relationship satisfaction	0.5	0.7	2.3	-0.0	-0.0	0.1	-1.5	-0.5	-0.6	-1.4	0.5	1.1	0.6
Knee pain experienced in last month	0.5	0.8	3.3	0.6	-0.6	-0.7	0.2	-0.0	1.8	-1.3	1.0	-0.2	-0.6
Smoking status: Previous	0.5	0.7	2.4	-0.9	0.3	1.0	-0.5	0.6	-0.1	0.4	1.6	0.7	1.3
Average weekly red wine intake	0.5	0.7	2.4	-0.5	0.5	0.5	-0.7	0.3	-1.5	1.5	-0.8	0.4	0.7
Handedness (chirality/laterality): Left-handed	0.5	0.6	3.1	-0.3	-0.1	0.4	-0.2	0.3	0.2	0.6	-1.8	-0.9	0.8
Medication: Blood pressure	0.5	0.9	1.9	1.4	-0.3	-1.1	-1.3	-0.8	1.0	-0.3	0.8	-0.6	-1.1
Medication: Atorvastatin	0.5	0.6	3.6	-0.2	0.3	0.2	0.3	-0.5	-0.3	-1.9	-0.8	0.1	-1.1
Alcohol drinker status: Previous	0.5	0.6	1.2	-0.8	0.9	1.1	-0.9	0.7	0.6	-0.4	-0.9	0.9	-0.3
Depression (Nagel 2018)	0.4	0.6	2.1	1.0	-0.6	-0.8	-0.8	-0.5	-1.4	-0.0	0.0	-0.4	-1.0
Alzheimer’s Disease (in father)	0.4	0.5	2.1	-0.8	1.4	0.7	0.2	0.1	-0.6	-0.5	-0.6	-0.1	0.8
Crohns Disease (2017)	0.4	0.8	6.2	-0.7	0.6	0.5	2.5	-0.3	0.2	0.2	-0.2	-0.9	0.0
Breast Cancer	0.4	1.0	2.8	1.0	-0.8	-1.6	-0.1	-1.7	0.0	0.3	-0.4	-1.4	-1.0
Lupus	0.4	0.7	4.7	0.1	-0.1	0.4	-2.2	0.3	-0.2	-0.3	-0.9	-0.6	0.4
Respiratory disease	0.4	0.9	4.1	0.8	0.4	-0.4	0.7	-0.6	1.2	-0.3	2.0	1.0	-0.5
Frequency of depressed mood in last 2 weeks	0.4	0.5	3.3	0.3	0.1	-0.1	-0.3	0.2	-0.5	0.1	1.8	0.8	-0.8
Systolic blood pressure, automated reading	0.4	1.1	2.7	-1.0	1.7	1.3	1.3	1.2	-1.3	0.2	-0.1	0.8	0.4
Vitamin and mineral supplements	0.4	0.5	2.0	-0.4	0.1	0.4	0.5	0.4	-0.4	0.3	1.4	1.2	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	2.2	1.1	-0.5	-1.2	1.1	-1.5	0.3	-1.1	-0.4	0.3	-0.8
Medication: Ramipril	0.4	0.5	2.6	-0.5	0.1	0.6	-0.4	-0.0	0.3	-1.6	-1.3	0.6	-0.2
Happiness	0.4	0.5	2.6	0.1	-0.4	-0.1	-1.2	0.6	0.1	-0.3	0.6	1.6	0.6
Illnesses of mother	0.4	0.5	1.4	-0.8	0.7	0.8	0.2	0.3	-0.8	-1.2	0.8	0.9	-0.5
Medication for pain relief, constipation, heartburn	0.4	0.6	1.5	0.6	-1.0	-0.5	-0.3	-0.1	-1.2	0.3	-1.2	-1.1	0.4
Medication: Omeprazole	0.4	0.4	2.0	0.6	0.4	-0.5	0.9	-0.1	1.4	0.6	0.2	-0.2	-0.3
Suffer from ‘nerves’	0.4	0.6	1.9	0.6	-0.9	-0.4	-1.4	-0.7	0.1	0.4	-0.7	-1.3	-0.4
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.3	0.3	-0.8	-0.2	0.1	1.1	-0.8	0.6	0.4	1.1	0.5
Commuting to job workplace: Public transport	0.4	0.5	1.3	-0.5	0.6	0.6	-0.8	1.1	-1.1	0.4	-0.6	0.4	0.5
Medication: Lisinopril	0.4	0.5	2.3	0.3	0.2	-0.3	-0.8	-0.9	-0.3	-0.4	1.5	-0.5	-0.5
Ever smoked	0.4	0.7	2.1	-1.0	0.0	1.2	-1.4	0.5	-0.0	-0.3	0.3	0.9	0.9
Number of operations (self-reported)	0.4	0.5	1.7	0.7	-0.3	-0.6	0.7	-1.3	-1.2	-0.4	-0.1	-0.2	-0.6
Commuting to job workplace: Cycle	0.4	0.5	1.4	-0.3	-0.5	0.4	-1.2	1.1	0.1	0.9	-0.1	1.0	0.1
Vascular/heart problems diagnosed by doctor	0.4	1.2	3.0	-0.4	0.2	0.2	1.6	1.0	1.3	1.7	0.5	0.2	1.7
Worry (Nagel 2018)	0.3	0.5	2.0	-0.1	0.2	0.5	-1.3	0.6	-0.6	1.4	-0.4	-0.2	0.7
Alzheimer’s Disease (including proxy)	0.3	0.5	2.2	-0.6	1.5	0.5	0.4	0.1	0.1	0.8	0.3	0.2	1.1
Irritable Bowel Disease (IBD)	0.3	0.7	5.3	0.0	0.8	-0.1	2.3	-0.6	-0.2	0.4	0.4	-0.9	-0.3
Verbal and Numeric Reasoning (VNR)	0.3	0.8	4.1	-0.5	0.7	0.4	-1.0	1.3	-0.2	2.0	-0.1	-0.1	0.6
Blood Red Count	0.3	3.4	25.8	1.4	-0.8	-0.4	-5.1	0.3	-1.3	1.2	0.3	-1.1	-0.8
Waist Hip Ratio (WHR)	0.3	1.2	5.3	0.9	-0.9	-1.2	0.2	-2.3	-0.0	-1.2	0.0	-1.0	-0.9
Smoking Status	0.3	0.7	2.7	0.4	-0.9	-0.2	-1.3	-1.3	0.2	-1.7	-0.2	-0.2	0.0
Cardiovascular Disease	0.3	1.0	2.3	1.1	-0.3	-0.7	-1.4	-1.1	0.5	-1.1	-0.9	-0.2	-1.5
Lung FEV1/FVC ratio	0.3	1.5	4.1	-1.2	0.3	0.8	-2.0	1.2	-1.2	1.2	1.3	0.9	1.5
Diabetes (father)	0.3	0.4	1.6	0.3	0.6	-0.3	0.7	-0.7	-0.7	-1.3	-0.0	0.2	-0.0
High blood pressure	0.3	0.7	2.1	-0.7	0.8	1.1	-1.5	0.1	-1.0	-0.8	-0.6	0.6	-0.5
Past tobacco smoking	0.3	0.6	1.4	0.9	-0.2	-1.1	0.9	-0.6	0.0	0.2	-0.9	-1.2	-1.0
Hair/balding pattern: Pattern 2	0.3	0.4	1.9	0.5	-1.4	-0.4	-0.6	0.1	0.7	0.0	1.1	-0.4	-0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	2.7	0.9	-0.4	-1.1	1.6	-1.2	0.2	-1.1	0.1	-0.0	-0.3
Mouth/teeth dental problems	0.3	0.4	3.6	0.1	0.3	-0.2	0.4	0.1	0.4	1.9	-0.2	-0.5	0.0
Illnesses of siblings	0.3	0.4	2.1	-0.4	0.9	0.1	-1.4	-0.4	-0.3	1.0	-0.0	-0.2	0.4
Falls in the last year	0.3	0.4	1.1	-0.0	0.3	0.1	-0.5	-0.9	0.6	-1.0	-0.6	-0.7	-0.4
Hair/balding pattern: Pattern 3	0.3	0.5	3.1	-0.3	0.4	0.4	0.6	0.7	0.3	-1.8	-0.4	0.2	-0.0
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.1	0.1	-1.0	-0.2	-0.8	-0.1	-0.1	-1.0	0.3	0.3	-0.5
Medication: Cholesterol lowering	0.3	0.4	1.7	0.3	0.1	-0.2	-0.9	-0.2	-1.3	-0.4	-0.4	-0.0	-1.1
Tense / ‘highly strung’	0.3	0.5	2.6	0.4	-0.1	-0.0	-1.6	-0.5	0.2	1.1	0.6	-0.3	0.9
Peak expiratory flow (PEF)	0.3	0.6	1.6	-0.6	0.9	0.4	-0.3	-0.0	-1.1	1.3	-0.4	0.5	1.1
Blood clot in the leg (DVT)	0.3	0.4	0.9	-0.7	0.4	0.7	-0.3	1.0	-0.6	-0.3	-0.6	0.9	0.7
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	2.0	0.3	-0.7	-0.2	-0.8	-0.0	1.3	-0.1	0.7	-1.4	0.0
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.3	-0.5	0.8	0.6	-1.1	0.5	-0.6	-0.3	0.4	0.9	0.1
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.0	-0.5	0.3	0.7	-1.0	-0.6	-1.0	-0.6	-0.1	0.1	0.7
High blood pressure (siblings)	0.3	0.4	1.2	0.6	-1.0	-0.4	1.1	0.4	-0.3	-0.8	-0.1	0.1	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.3	-0.4	0.5	0.7	-1.0	0.2	0.0	0.0	0.3	1.1	0.5
Number of children fathered	0.3	0.3	1.0	0.5	-0.1	-0.1	-1.0	-0.6	0.8	-0.3	0.8	-0.3	0.2
Medication: Allopurinol	0.3	0.3	1.8	0.2	0.1	-0.4	-1.3	-0.6	-0.5	0.3	-0.2	-0.8	0.1
Medication: Seretide 50 evohaler	0.3	0.4	1.1	0.2	-0.4	-0.2	1.0	-0.3	0.6	-1.1	-0.1	0.9	-0.2
Mean time to correctly identify matches	0.3	0.5	1.5	-0.7	-0.0	1.0	-1.2	0.3	0.5	-0.4	-0.2	-0.3	1.1
Pulse rate, automated reading	0.3	0.9	2.6	1.4	-0.5	-1.5	-0.6	-0.7	-0.1	0.4	-0.4	-1.6	-0.7
Comparative height size at age 10	0.3	1.4	8.6	1.6	-1.0	-0.9	-2.9	0.2	-0.0	-0.4	-0.2	-0.7	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.2	-0.3	1.0	0.4	-0.2	0.4	0.4	0.7	-0.5	1.1	0.6
Mood swings	0.3	0.5	1.4	0.5	-0.3	-0.4	-1.0	-0.9	-0.7	-0.7	1.2	-0.0	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.9	0.6	-0.5	-0.4	-1.0	-0.3	-0.1	0.2	1.0	0.7	-0.4
Eye problems/disorders: Cataract	0.3	0.3	0.8	0.4	-0.1	-0.6	0.9	-0.9	-0.0	0.7	-0.2	-0.3	0.4
Breast cancer (self-reported)	0.3	0.4	1.3	0.3	-0.9	-0.4	-0.1	-0.5	-0.7	-1.1	0.8	-0.5	0.2
Medication: Aspirin	0.3	0.4	1.1	-0.0	0.9	-0.1	0.1	-1.0	-0.7	-0.7	0.4	-0.3	-0.8
Number of self-reported non-cancer illnesses	0.3	0.6	1.5	0.5	0.4	-0.3	-1.0	-0.9	-1.2	-0.7	0.5	-0.6	-1.0
Guilty feelings	0.3	0.5	2.4	-0.8	0.0	0.6	0.0	0.4	0.1	0.5	-0.9	0.5	1.5
Irritability	0.3	0.4	2.1	-0.1	0.3	0.3	-1.4	0.7	0.1	1.1	0.1	0.4	0.4
Fractured/broken bones in last 5 years	0.3	0.3	1.6	-0.2	0.6	0.0	0.9	-0.5	-0.4	0.2	0.2	-1.3	0.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.3	0.6	0.3	-0.5	0.8	-0.5	1.1	0.5	0.5	-0.7	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.0	-0.7	0.5	0.6	-0.3	0.9	-0.7	-0.3	-0.2	1.0	0.7
Ulcerative Colitis (UC)	0.2	0.3	0.9	0.7	0.3	-0.6	1.0	-0.5	-0.8	0.2	0.6	-0.2	-0.4
Blood White Count	0.2	1.3	3.6	1.3	-1.1	-1.6	-0.6	-0.6	-0.3	0.6	-1.9	-0.6	-1.6
Heel T-Score	0.2	2.0	17.7	-0.0	-0.1	-0.7	4.2	-0.4	0.7	-0.3	-0.5	0.3	-0.6
Height	0.2	3.7	25.0	1.9	-1.0	-0.8	-5.0	0.4	0.5	-0.0	-2.2	-0.9	0.7
Neuroticism	0.2	0.4	1.5	0.1	-0.2	-0.0	-1.1	-0.2	1.2	-0.1	-0.2	-0.5	0.8
Hair Pigment	0.2	5.3	10.4	2.6	-2.2	-2.9	-2.6	-3.2	-1.9	-0.8	-1.2	-1.3	-2.8
Number of treatments/medications taken	0.2	0.4	1.2	-0.0	0.6	-0.1	-0.0	-0.3	-0.5	-0.8	1.0	0.5	-1.1
Sensitivity / hurt feelings	0.2	0.3	0.7	-0.1	0.6	-0.1	0.7	-0.4	0.6	-0.7	-0.8	0.3	0.6
Relative age of first facial hair	0.2	0.5	1.3	-0.1	-0.0	-0.3	0.8	0.8	0.8	0.8	0.9	1.1	0.2
Fluid intelligence score	0.2	0.5	1.3	-0.9	0.6	0.8	0.0	1.0	0.3	1.1	-0.1	0.3	0.6
Neuroticism score	0.2	0.3	1.2	-0.1	-0.0	0.2	-0.8	0.5	0.9	0.2	0.4	-0.1	1.1
Number of live births	0.2	0.3	0.7	0.2	-0.4	-0.3	-0.7	-0.7	0.3	-0.8	-0.4	0.4	-0.8
Prospective memory result	0.2	0.2	1.1	-0.0	0.6	0.2	-0.1	0.1	1.0	-0.8	0.5	0.1	0.2
Hair/balding pattern: Pattern 4	0.2	0.5	4.0	0.0	0.0	0.1	-0.5	-0.7	-2.0	-0.2	-0.1	0.5	0.5
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.9	0.1	-0.3	0.2	-0.7	0.6	0.1	-0.1	0.7	0.5	0.9
Medication: Ibuprofen	0.2	0.2	1.0	-0.0	-0.7	-0.2	-0.2	-0.3	0.4	-1.0	0.5	-0.1	-0.6
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.7	-0.1	0.0	0.1	0.7	-0.1	0.8	0.5	-0.5	-0.7	-0.4
Medication: Aspirin	0.2	0.3	1.0	-0.2	1.0	0.1	-0.0	-0.7	-0.6	-0.4	0.6	0.2	-0.4
Hypertension (Self-reported)	0.2	0.6	1.8	-0.5	0.8	0.9	-1.4	-0.1	-0.5	-1.0	-0.7	0.5	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.2	0.4	-0.9	-0.3	0.5	-0.3	0.3	-0.3	-0.4	1.1	-0.3
Illnesses of father: None of the above (group 1)	0.2	0.3	1.4	0.1	-0.2	-0.0	-1.2	-0.2	-0.1	0.9	-0.0	0.2	-0.2
Miserableness	0.2	0.4	0.8	0.7	-0.7	-0.6	-0.8	-0.5	-0.1	-0.9	0.8	-0.1	-0.4
Diastolic blood pressure, automated reading	0.2	0.7	3.3	0.0	0.5	0.4	0.6	1.4	0.3	0.5	1.8	0.8	0.4
Myopia	0.2	0.3	1.3	-0.3	-0.6	0.2	-0.6	-0.2	-1.1	-0.2	-0.1	0.4	-0.3
Neuroticism (Nagel 2018)	0.1	0.3	1.0	0.0	-0.0	0.2	-1.0	0.1	-0.2	1.0	-0.7	-0.5	0.7
Alzheimer’s Disease (in mother)	0.1	0.2	0.5	-0.1	0.6	0.0	0.1	-0.6	-0.4	0.7	0.4	-0.2	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.7	0.5	-0.5	-0.2	-0.4	-0.1	-0.1	-0.6	0.8	0.3	-0.2
Multivitamins +/- minerals	0.1	0.1	0.5	0.3	0.2	-0.2	-0.2	0.5	-0.2	0.7	-0.4	-0.5	-0.4
Standing height	0.1	1.3	5.8	0.8	0.4	-0.2	-1.9	1.0	2.4	0.4	-0.8	0.4	0.9
Bipolar Disorder (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder or Schizophrenia	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Tanning	0.0	0.2	0.7	-0.3	-0.1	0.0	0.4	-0.1	0.9	0.0	-0.7	0.8	-0.2

Hub : Genes

BTBD2

Models

Trait associations