Best TWAS P=8.28e-10 · Best GWAS P=4.03e-15 conditioned to 1.41e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | CADM2 | 0.05 | 0.06 | lasso | 10 | 0.06 | 1.3e-09 | 4.6 | 5.4 | 6.0e-08 | -0.18 | 1.00 | 0.00 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CADM2 | 0.06 | 0.00 | blup | 339 | 0.00 | 2.7e-01 | -4.8 | -6.0 | 1.5e-09 | 0.67 | 0.04 | 0.44 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | CADM2 | 0.08 | 0.04 | lasso | 4 | 0.05 | 2.1e-06 | 5.5 | 6.1 | 8.3e-10 | -0.36 | 0.98 | 0.01 | TRUE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CADM2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 5.0e-05 | 5.5 | 6.1 | 1.2e-09 | -0.31 | 0.92 | 0.02 | FALSE |