[Hub]/) : Traits : Waist circumference :

chr3:87,495,550-88,911,119

Best TWAS P=1.82e-09 · Best GWAS P=2.15e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C3orf38 0.08 0.00 enet 14 0.04 2.3e-05 -5.1 -5.8 7.3e-09 0.63 0.05 0.90 FALSE
2 GTEx Artery Aorta C3orf38 0.06 0.06 lasso 7 0.05 6.0e-04 -5.2 5.2 2.4e-07 -0.80 0.30 0.56 FALSE
3 GTEx Cells Transformed fibroblasts ZNF654 0.08 0.09 enet 6 0.10 3.1e-08 -5.9 -6.0 1.8e-09 0.99 0.01 0.99 TRUE
4 GTEx Esophagus Mucosa C3orf38 0.11 0.06 lasso 7 0.07 1.5e-05 -5.1 5.6 1.7e-08 -0.91 0.10 0.90 FALSE
5 GTEx Nerve Tibial C3orf38 0.09 0.05 lasso 4 0.04 6.3e-04 -5.1 5.2 2.5e-07 -0.80 0.33 0.55 FALSE
6 GTEx Testis C3orf38 0.11 0.01 enet 12 0.00 1.9e-01 -5.5 5.3 9.0e-08 -0.42 0.09 0.41 FALSE
7 The Cancer Genome Atlas Thyroid Carcinoma ZNF654 0.03 0.04 lasso 3 0.03 4.6e-04 -5.1 -5.1 2.7e-07 0.80 0.02 0.93 FALSE