Best TWAS P=1.82e-09 · Best GWAS P=2.15e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C3orf38 | 0.08 | 0.00 | enet | 14 | 0.04 | 2.3e-05 | -5.1 | -5.8 | 7.3e-09 | 0.63 | 0.05 | 0.90 | FALSE |
| 2 | GTEx | Artery Aorta | C3orf38 | 0.06 | 0.06 | lasso | 7 | 0.05 | 6.0e-04 | -5.2 | 5.2 | 2.4e-07 | -0.80 | 0.30 | 0.56 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | ZNF654 | 0.08 | 0.09 | enet | 6 | 0.10 | 3.1e-08 | -5.9 | -6.0 | 1.8e-09 | 0.99 | 0.01 | 0.99 | TRUE |
| 4 | GTEx | Esophagus Mucosa | C3orf38 | 0.11 | 0.06 | lasso | 7 | 0.07 | 1.5e-05 | -5.1 | 5.6 | 1.7e-08 | -0.91 | 0.10 | 0.90 | FALSE |
| 5 | GTEx | Nerve Tibial | C3orf38 | 0.09 | 0.05 | lasso | 4 | 0.04 | 6.3e-04 | -5.1 | 5.2 | 2.5e-07 | -0.80 | 0.33 | 0.55 | FALSE |
| 6 | GTEx | Testis | C3orf38 | 0.11 | 0.01 | enet | 12 | 0.00 | 1.9e-01 | -5.5 | 5.3 | 9.0e-08 | -0.42 | 0.09 | 0.41 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | ZNF654 | 0.03 | 0.04 | lasso | 3 | 0.03 | 4.6e-04 | -5.1 | -5.1 | 2.7e-07 | 0.80 | 0.02 | 0.93 | FALSE |