Best TWAS P=2.61e-12 · Best GWAS P=5.27e-11 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | ZBTB38 | 0.08 | 0.04 | lasso | 4 | 0.03 | 8.1e-04 | 6.5 | 6.6 | 5.1e-11 | 0.51 | 0.03 | 0.96 | FALSE |
2 | GTEx | Testis | ZBTB38 | 0.14 | 0.06 | lasso | 8 | 0.05 | 2.8e-03 | 6.4 | 6.5 | 6.4e-11 | 0.91 | 0.04 | 0.93 | FALSE |
3 | GTEx | Thyroid | ZBTB38 | 0.11 | 0.03 | enet | 32 | 0.04 | 2.9e-04 | 4.7 | 5.7 | 9.1e-09 | 0.57 | 0.12 | 0.86 | FALSE |
4 | NTR | Blood | ZBTB38 | 0.03 | 0.01 | lasso | 3 | 0.01 | 2.2e-05 | 6.4 | 5.8 | 7.9e-09 | 0.43 | 0.02 | 0.98 | FALSE |
5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ZBTB38 | 0.04 | 0.03 | lasso | 3 | 0.04 | 3.0e-03 | 6.6 | 7.0 | 2.6e-12 | 0.97 | 0.02 | 0.76 | TRUE |