Best TWAS P=1.62e-10 · Best GWAS P=7.45e-13 conditioned to 0.000983
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | PCCB | 0.12 | 0.03 | enet | 11 | 0.09 | 2.0e-05 | -6.8 | 5.8 | 8.7e-09 | -0.79 | 0.12 | 0.83 | FALSE |
| 2 | GTEx | Brain Cerebellar Hemisphere | RP11-731C17.2 | 0.16 | 0.02 | enet | 24 | 0.09 | 3.0e-03 | -5.9 | 6.4 | 1.6e-10 | -0.85 | 0.08 | 0.67 | TRUE |
| 3 | GTEx | Brain Hippocampus | RP11-731C17.2 | 0.19 | 0.06 | enet | 24 | 0.11 | 1.8e-03 | -2.6 | 5.8 | 6.7e-09 | -0.72 | 0.10 | 0.68 | FALSE |
| 4 | GTEx | Esophagus Mucosa | RP11-85F14.5 | 0.13 | 0.10 | lasso | 3 | 0.11 | 5.1e-08 | -5.2 | 5.2 | 1.7e-07 | -0.64 | 0.99 | 0.01 | FALSE |
| 5 | GTEx | Lung | RP11-85F14.5 | 0.07 | 0.05 | lasso | 19 | 0.05 | 8.8e-05 | -5.2 | 5.6 | 2.2e-08 | -0.67 | 0.92 | 0.04 | FALSE |
| 6 | GTEx | Thyroid | RP11-85F14.5 | 0.07 | 0.00 | lasso | 7 | 0.01 | 4.7e-02 | -5.2 | 6.3 | 3.3e-10 | -0.70 | 0.07 | 0.52 | FALSE |
| 7 | ROSMAP | Brain Pre-frontal Cortex | PCCB | 0.10 | 0.07 | lasso | 4 | 0.10 | 4.2e-13 | 3.3 | 5.7 | 9.0e-09 | -0.78 | 0.24 | 0.76 | FALSE |
| 8 | YFS | Blood | NCK1 | 0.01 | 0.02 | enet | 4 | 0.02 | 2.2e-06 | -5.2 | 5.2 | 1.8e-07 | -0.64 | 0.97 | 0.01 | FALSE |
| 9 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | PCCB | 0.07 | 0.06 | blup | 53 | 0.06 | 2.1e-04 | 2.3 | 5.2 | 1.7e-07 | -0.69 | 0.10 | 0.63 | FALSE |
| 10 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | PCCB | 0.13 | 0.02 | blup | 53 | 0.02 | 4.4e-02 | 1.5 | 5.4 | 5.1e-08 | -0.70 | 0.02 | 0.33 | FALSE |